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1. Full Text Quinolinic acid, the inescapable neurotoxin
by Guillemin, Gilles J
The FEBS journal, ISSN 1742-464X, 04/2012, Volume 279, Issue 8, pp. 1356 - 1365
neurodegeneration | quinolinic acid | kynurenine pathway | neuroinflammation | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Neurotoxicity Syndromes - etiology | Quinolinic Acid - adverse effects | Animals | Humans | Neurotoxins - adverse effects | Methyl aspartate | Nervous system diseases | Brain | Cytotoxicity | Neurotoxicity | Biochemistry | Toxins | Index Medicus
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2. Full Text Kynurenine Pathway Metabolites in Humans: Disease and Healthy States
by Yiquan Chen and Gilles J. Guillemin
International journal of tryptophan research, ISSN 1178-6469, 01/2009, Volume 2009, Issue 2, pp. 1 - 19
Tryptophan | Enzymes | Interferon | Metabolites | Biological response modifiers
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3. Full Text Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?
by Steiner, Johann and Walter, Martin and Gos, Tomasz and Guillemin, Gilles J and Bernstein, Hans-Gert and Sarnyai, Zoltán and Mawrin, Christian and Brisch, Ralf and Bielau, Hendrik and zu Schwabedissen, Louise M and Bogerts, Bernhard and Myint, Aye-Mu
Journal of neuroinflammation, ISSN 1742-2094, 08/2011, Volume 8, Issue 1, pp. 94 - 94
Neurosciences | Immunology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Depressive Disorder, Major - physiopathology | Microglia - metabolism | Synaptic Transmission - physiology | Humans | Middle Aged | Male | Tryptophan - metabolism | Gyrus Cinguli - metabolism | Quinolinic Acid - metabolism | Serotonin - metabolism | Gyrus Cinguli - anatomy & histology | Adult | Female | Aged | Glutamic Acid - metabolism | Depression, Mental | Physiological aspects | Research | Quinolinic acid | Health aspects | Risk factors | Gyrus cinguli | Studies | Enzymes | Brain | Social research | Serotonin | Rodents | Bipolar disorder | Behavior | Forensic medicine | Mass spectrometry | Index Medicus
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4. Full Text The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review
by Manoharan, Shanmugam and Guillemin, Gilles J and Abiramasundari, Rajagopal Selladurai and Essa, Musthafa Mohamed and Akbar, Mohammed and Akbar, Mohammed D
Oxidative medicine and cellular longevity, ISSN 1942-0900, 12/2016, Volume 2016, pp. 8590578 - 15
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Parkinson Disease - pathology | Reactive Oxygen Species - metabolism | Oxidative Stress | Humans | Huntington Disease - pathology | Alzheimer Disease - drug therapy | Parkinson Disease - drug therapy | Huntington Disease - metabolism | Alzheimer Disease - pathology | Alzheimer Disease - metabolism | Parkinson Disease - metabolism | Huntington Disease - drug therapy | Biological Products - therapeutic use | Medicinal plants | Antioxidants | Advertising executives | Medical research | Medicine, Botanic | Medicine, Experimental | Medicine, Herbal | Alzheimer's disease | Huntingtons disease | Oxidative stress | Oxygen | Seeds | Pathogenesis | Parkinsons disease | Lipid peroxidation | Lipids | Metabolism | Studies | Brain research | Neurodegeneration | Natural products | Older people | Cell cycle | Physiology | Alzheimers disease | Dementia | Index Medicus | Review
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5. Full Text Quinolinic acid: neurotoxicity
by Guillemin, Gilles J
The FEBS journal, ISSN 1742-464X, 04/2012, Volume 279, Issue 8, pp. 1355 - 1355
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Neurotoxicity Syndromes - etiology | Quinolinic Acid - adverse effects | Animals | Humans | Index Medicus
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6. Major developments in the design of inhibitors along the kynurenine pathway
by Jacobs, Kelly R and Castellano-González, Gloria and Guillemin, Gilles J and Lovejoy, David B
Current medicinal chemistry, ISSN 0929-8673, 2017, Volume 24, Issue 23, pp. 2471 - 2495
Kynurenine Pathway | Kynurenine 3-monooxygenase | Indoleamine 2,3-dioxygenase | Enzyme inhibitors | Neurodegeneration | Cancer | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Enzyme Inhibitors - metabolism | Kynurenine 3-Monooxygenase - antagonists & inhibitors | Enzyme Inhibitors - chemistry | Humans | Drug Design | Enzyme Inhibitors - pharmacology | Transaminases - metabolism | Transaminases - antagonists & inhibitors | Kynurenine 3-Monooxygenase - metabolism | Kynurenine - metabolism | Indoleamine-Pyrrole 2,3,-Dioxygenase - antagonists & inhibitors | Enzymes | Enzyme activity | Mental disorders | Tryptophan 2,3-dioxygenase | Metabolism | Monooxygenase | Kynurenine-oxoglutarate transaminase | Inhibitors | Molecular modelling | Enzymatic activity | Crystal structure
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