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Nature, ISSN 0028-0836, 09/2016, Volume 537, Issue 7621, pp. 539 - 543
Journal Article
Journal Article
European Journal of Immunology, ISSN 0014-2980, 08/2015, Volume 45, Issue 8, pp. 2389 - 2395
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 5336 - 9
Cish, participates within a multi-molecular E3 ubiquitin ligase complex, which ubiquitinates target proteins. It has an inhibitory effect on T cell activation... 
Ubiquitin | Calcium | CD8 antigen | T cell receptors | Lymphocytes T | Tumor necrosis factor-α | T-cell receptor | Ubiquitination | Cell activation | Lymphocytes | Immunotherapy | γ-Interferon | Ubiquitin-protein ligase | Cytoplasm | Structure-function relationships
Journal Article
Developmental and Comparative Immunology, ISSN 0145-305X, 07/2018, Volume 84, p. 193
Downstream of Kinase (DOK) proteins represent a multigenic family of adaptors that includes negative regulators of immune cell signaling. Using phylogenetics... 
Adaptor proteins | Tyrosine | Regulators | Genes | Biological evolution | Evolutionary genetics | Dok1 protein | Phylogeny | Kinases | Gene expression | Adaptors | Gene sequencing | Proteins | Signal transduction | Vertebrates | Reproduction (copying) | Pattern analysis | Immune system
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2013, Volume 4, p. 80
Phosphoinositides are critical regulators in cell biology. Phosphatidylinositol 4,5-bisphosphate, also known as PI(4,5)P2 or PIP2, was the first variety of... 
PI5P | Phosphoinositide | PtdIns5P | T cell signaling | Dok proteins | Life Sciences | Human health and pathology | Immunology | Infectious diseases | T cell | cell signaling | phospholipid | phosphoinositide
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 06/2019, Volume 10, p. 1307
Women with low levels of vitamin D have a higher risk of developing breast cancer. Numerous studies associated the presence of a CD8+ T cell infiltration with... 
CD8+T cells | immunonutrition | vitamin D | SYSTEMIC IMMUNE ACTIVATION | breast cancer | RISK | IMMUNOLOGY | DIET-INDUCED OBESITY | inflammation | BODY-MASS INDEX | WEIGHT-GAIN | PROGNOSTIC-SIGNIFICANCE | EXPRESSION | T-CELLS | ADIPOSE-TISSUE | LYMPHOCYTES | Vitamin D | Growth | Oncology, Experimental | Development and progression | Calcifediol | Breast cancer | Research | Alfacalcidol | T cells | Cancer | Diagnosis | Health aspects | CD8+ T cells
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2015, Volume 212, Issue 12, pp. 2095 - 2113
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2019, Volume 202, Issue 4, pp. 1250 - 1264
Recent insight into the mechanisms of induction of tissue-resident memory (T-RM) CD8(+) T cells (CD8(+) T-RM) enables the development of novel vaccine... 
MIGRATION | NONLYMPHOID TISSUE | RECALL RESPONSES | RM CELLS | TUMOR-REGRESSION | LOCAL ANTIGEN | INFECTION | SKIN | DIFFERENTIATION | IMMUNOLOGY | CUTTING EDGE
Journal Article
European Journal of Immunology, ISSN 0014-2980, 08/2015, Volume 45, Issue 8, pp. 2389 - 2395
Journal Article
European Journal of Immunology, ISSN 0014-2980, 08/2015, Volume 45, Issue 8, pp. 2389 - 2395
Sos-1 and Sos-2 are ubiquitously expressed Ras-guanine exchange factors involved in Erk-MAP kinase pathway activation. Using mice lacking genes encoding Sos-1... 
Journal Article
Developmental and Comparative Immunology, ISSN 0145-305X, 07/2018, Volume 84, pp. 193 - 198
Downstream of Kinase (DOK) proteins represent a multigenic family of adaptors that includes negative regulators of immune cell signaling. Using phylogenetics... 
Adapter molecules | Immune cell signaling | DOK genes | ACTIVATION | ADAPTERS | IMMUNOLOGY | ALIGNMENTS | REGULATOR | P62(DOK) | FISHERIES | ZOOLOGY | NEURITE OUTGROWTH | NEGATIVE REGULATION | T-CELL-RECEPTOR | DIFFERENTIATION | PROMOTES | Proteins | Tyrosine | Anopheles | Analysis | Genes | Genetic research | Phylogeny | Life Sciences | Immunology
Journal Article
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2018, Volume 8, Issue 5336
Cish, participates within a multi-molecular E3 ubiquitin ligase complex, which ubiquitinates target proteins. It has an inhibitory effect on T cell activation... 
BINDS | PATHWAY | MULTIDISCIPLINARY SCIENCES | INVOLVEMENT | RECEPTOR | CANCER-IMMUNOTHERAPY | SH2-CONTAINING PROTEIN | STAT5 ACTIVATION | Life Sciences
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 03/2017, Volume 8, p. 343
RAS signaling is central to many cellular processes and SOS proteins promote RAS activation. To investigate the role of SOS proteins in T cell biology, we... 
Chondrocyte dysplasia | Cartilage homeostasis | Proliferation | RAS | T cell signaling | SOS | LOCALIZATION | ACTIVATION | cartilage homeostasis | proliferation | PATHWAY | GROWTH | IMMUNOLOGY | T-CELL DEVELOPMENT | chondrocyte dysplasia | Physiological aspects | Cartilage cells | CD4 lymphocytes
Journal Article