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Nature Medicine, ISSN 1078-8956, 08/2015, Volume 21, Issue 8, pp. 914 - 921
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2018, Volume 24, Issue 5, pp. 563 - 571
Journal Article
Nature, ISSN 0028-0836, 06/2018, Volume 558, Issue 7709, pp. 307 - 312
Cancer immunotherapy based on genetically redirecting T cells has been used successfully to treat B cell malignancies(1-3). In this strategy, the T cell genome... 
B-CELL | 5-METHYLCYTOSINE | CONVERSION | MULTIDISCIPLINARY SCIENCES | 5-HYDROXYMETHYLCYTOSINE | MUTATIONS | PROTEINS | CD28 COSTIMULATION | DNA INTEGRATION | 5-FORMYLCYTOSINE | LYMPHOCYTES | Clone Cells - cytology | Dioxygenases - metabolism | Immunotherapy - methods | Epigenesis, Genetic | Humans | Male | Adoptive Transfer | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Recombinant Fusion Proteins - metabolism | T-Lymphocytes - transplantation | T-Lymphocytes - metabolism | Clone Cells - immunology | HEK293 Cells | Cell Differentiation | Transgenes | Leukemia, Lymphocytic, Chronic, B-Cell - immunology | Antigens, CD19 - immunology | Clinical Trials as Topic | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Leukemia, Lymphocytic, Chronic, B-Cell - therapy | Dioxygenases - genetics | 5-Methylcytosine - metabolism | T-Lymphocytes - cytology | Alleles | Recombinant Fusion Proteins - genetics | T-Lymphocytes - immunology | Aged | Mutation | Genetic engineering | Research | T cells | Immunotherapy | Oncology, Experimental | Cancer | Leukemia | Differentiation (biology) | Insertion | Genomes | Lymphocytes T | Lymph nodes | Anticancer properties | Proteins | Infusion | Receptors | Lymphocytes | Peripheral blood | Bone marrow | Remission | Oxidation | Bioinformatics | Deoxyribonucleic acid--DNA | Dioxygenase | Antigens | Chronic lymphatic leukemia | Phenotypes | Transposons | CD19 antigen | Cloning | T cell receptors | Cell differentiation | Patients | Progeny | Lymphocytes B | Stem cells | Epigenetics | Tumors
Journal Article
Molecular Therapy, ISSN 1525-0016, 01/2018, Volume 26, Issue 1, pp. 269 - 279
Journal Article
Science Translational Medicine, ISSN 1946-6234, 08/2013, Volume 5, Issue 197, pp. 197ra103 - 197ra103
Journal Article
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2016, Volume 75, Issue 5, pp. 1054 - 1057
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 699 - 699
Abstract We recently demonstrated that sustained remission in 41 CLL patients treated with the CD19-specific, 4-1BB/CD3zeta-signaling chimeric antigen receptor... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 5702 - 5702
Abstract Neurologic toxicity has been observed with anti-CD19 chimeric antigen receptor (CAR) T cells and the anti-CD19 BiTE blinatumomab. Both focal (e.g.,... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 974 - 974
Abstract Background: Though CD19 is expressed only rarely on multiple myeloma (MM) plasma cells (PC), rare CD19+ B cells can be identified in MM patients that... 
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 163 - 163
Abstract Background Recent advances in T cell engineering have enabled clinical trials to evaluate the potential for adoptive transfer of T cells to target... 
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 766 - 766
Abstract Background Despite recent therapeutic advances, multiple myeloma (MM) remains primarily an incurable cancer. Patients experiencing rapid recovery of T... 
Journal Article
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