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Trends in Molecular Medicine, ISSN 1471-4914, 07/2016, Volume 22, Issue 7, pp. 545 - 564
Autoinflammatory skin disorders are a group of heterogeneous diseases that include diseases such as cryopyrin-associated periodic syndrome (CAPS) and familial... 
autoimmune | IL-1 | inflammasome | Sharpin | inflammatory | NLRP3 | Ptpn6 | CAPS | FMF | Skin diseases | Analysis | Skin
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 8/2016, Volume 73, Issue 16, pp. 3035 - 3051
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 06/2018, Volume 103, Issue 6, pp. 1165 - 1177
Inflammasomes are multimeric protein complexes that promote inflammation (through specific cleavage and production of bioactive IL‐1β and IL‐18) and pyroptotic... 
negative regulation | ASC | NLRP3 | caspase‐1 | inflammasome | caspase-1 | ACTIVATION | DOMAIN | PROTEIN | IMMUNOLOGY | NALP3 INFLAMMASOME | CELL BIOLOGY | GASDERMIN D | INHIBITION | IL-1-BETA | HEMATOLOGY | NF-KAPPA-B
Journal Article
Cellular Microbiology, ISSN 1462-5814, 09/2015, Volume 17, Issue 9, pp. 1286 - 1294
Journal Article
Cellular Microbiology, ISSN 1462-5814, 09/2015, Volume 17, Issue 9, pp. 1286 - 1294
Summary Leishmaniasis is a major health problem that affects more than 300 million people throughout the world. The morbidity associated with the disease... 
TLR | complement | NLR | Leishmania | Complement | HUMAN-SERUM | DONOVANI PROMASTIGOTES | MICROBIOLOGY | MACROPHAGE ACTIVATION | CELL BIOLOGY | NATURAL MODEL | PROTECTIVE IMMUNITY | MAJOR PROMASTIGOTES | TOLL-LIKE RECEPTORS | LIPOPHOSPHOGLYCAN LPG | VISCERAL LEISHMANIASIS | Leishmaniasis - immunology | Immunity, Innate | Leishmania - immunology | Humans | Parasitic diseases | Tropical diseases
Journal Article
Nature, ISSN 0028-0836, 12/2014, Volume 516, Issue 7530, pp. 246 - 249
The incidences of chronic inflammatory disorders have increased considerably over the past three decades(1). Recent shifts in dietary consumption may have... 
HOMEOSTASIS | ACTIVATION | MULTIDISCIPLINARY SCIENCES | INFLAMMASOME | DEFICIENT | PROTEINASE-3 | IL-1-BETA | CASPASE-8 | MICE | RECEPTORS | CELL | Intestines - drug effects | Inflammation - pathology | Inflammasomes - metabolism | Cytoskeletal Proteins - genetics | Caspase 8 - metabolism | Microbiota - drug effects | Body Weight - drug effects | Male | Intestines - immunology | Cytoskeletal Proteins - deficiency | Interleukin-1beta - blood | Caspase 8 - genetics | Inflammation - diet therapy | Myeloblastin - deficiency | Interleukin-1beta - metabolism | Diet, High-Fat | Osteomyelitis - pathology | Prevotella - growth & development | Female | Neutrophils - metabolism | Osteomyelitis - diet therapy | Disease Models, Animal | Pancreatic Elastase - deficiency | Neutrophils - drug effects | Animals | Intestines - microbiology | Caspase 1 - genetics | Adaptor Proteins, Signal Transducing - deficiency | Adaptor Proteins, Signal Transducing - genetics | Caspase 1 - deficiency | Cholesterol - pharmacology | Mice | Mice, Inbred BALB C | Prevotella - isolation & purification | Physiological aspects | Physiological research | Inflammation | Research | Microbiota (Symbiotic organisms) | Diet | Microorganisms | Bone diseases | Antibiotics | Rodents | Inflammatory diseases | Index Medicus | caspase-8 | NLR | inflammasome | autoinflammation | Pstpip2 | IL-1β | RIP3 | caspase-1 | microbiome | neutrophils | dysbiosis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2016, Volume 113, Issue 16, p. 4452
  Missense mutation in the proline-serine-threonine phosphatase-interacting protein 2 (Pstpip2) gene results in the development of spontaneous chronic bone... 
Proteins | Bones | Inflammation | Mutation
Journal Article