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performing operations (69) 69
transporting (69) 69
conveying (61) 61
handling thin or filamentary material (61) 61
packing (61) 61
storing (61) 61
machines, apparatus or devices for, or methods of, packagingarticles or materials (50) 50
unpacking (50) 50
accessories, closures, or fittings therefor (38) 38
containers for storage or transport of articles or materials,e.g. bags, barrels, bottles, boxes, cans, cartons, crates,drums, jars, tanks, hoppers, forwarding containers (38) 38
packages (38) 38
packaging elements (38) 38
human necessities (28) 28
hygiene (26) 26
medical or veterinary science (26) 26
after-treatment of the shaped products, e.g. repairing (18) 18
shaping of material in a plastic state, not otherwise providedfor (18) 18
shaping or joining of plastics (18) 18
working of plastics (18) 18
working of substances in a plastic state, in general (18) 18
baby comforters (16) 16
containers specially adapted for medical or pharmaceuticalpurposes (16) 16
devices for administering food or medicines orally (16) 16
devices for receiving spittle (16) 16
devices or methods specially adapted for bringingpharmaceutical products into particular physical oradministering forms (16) 16
humans (15) 15
index medicus (14) 14
general tagging of cross-sectional technologies spanning over several sections of the ipc (12) 12
general tagging of new technological developments (12) 12
technical subjects covered by former uspc (12) 12
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (12) 12
chemical aspects of bandages, dressings, absorbent pads, orsurgical articles (10) 10
devices for introducing media into, or onto, the body (10) 10
devices for producing or ending sleep or stupor (10) 10
devices for transducing body media or for taking media fromthe body (10) 10
disinfection, sterilisation, or deodorisation of air (10) 10
materials for bandages, dressings, absorbent pads, or surgicalarticles (10) 10
methods or apparatus for sterilising materials or objects ingeneral (10) 10
oncology (10) 10
technical subjects covered by former us classification (10) 10
animals (9) 9
bottles, jars or similar containers (8) 8
cleaning, filling with liquids or semiliquids, or emptying, ofbottles, jars, cans, casks, barrels, or similar containers, nototherwise provided for (8) 8
funnels (8) 8
liquid handling (8) 8
opening, closing (8) 8
cancer (6) 6
female (6) 6
cell line, tumor (5) 5
mice (5) 5
neoplasms - drug therapy (5) 5
phosphatidylinositol 3-kinases - antagonists & inhibitors (5) 5
potent (5) 5
chemistry, medicinal (4) 4
class i phosphatidylinositol 3-kinases (4) 4
models, molecular (4) 4
mutation (4) 4
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protein kinase inhibitors - chemistry (4) 4
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rats (4) 4
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phosphatidylinositol 3-kinases - chemistry (3) 3
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protein kinase inhibitors - pharmacokinetics (3) 3
thiazoles - chemistry (3) 3
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tumors (3) 3
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3-kinase (2) 2
activity index (2) 2
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Journal Article
Journal Article
eLife, ISSN 2050-084X, 05/2015, Volume 4, Issue MAY
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 09/2015, Volume 25, Issue 17, pp. 3575 - 3581
Journal Article
BMC Cancer, ISSN 1471-2407, 12/2011, Volume 11, Issue 1
Journal Article
BMC Cancer, ISSN 1471-2407, 01/2011, Volume 11, p. 24
The JAK2.sup.V617F .sup.mutation plays a major role in the pathogenesis of myeloproliferative neoplasms and is found in the vast majority of patients suffering... 
Care and treatment | Myelofibrosis | Enzyme inhibitors | Patient outcomes | Physiological aspects | Dosage and administration | Cellular signal transduction | Research
Journal Article
eLife, ISSN 2050-084X, 11/2016, Volume 5
Sonkin’s approach would require multiple technologies to measure p53 gene expression and p53 copy number in addition to sequencing the full-length of p53 for... 
Mutation | Gene expression | p53 Protein | Response rates
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 02/2012, Volume 11, Issue 2, pp. 317 - 328
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 10/2017, Volume 80, Issue 4, pp. 869 - 878
Everolimus is a drug used successfully in a number of different oncology indications, but significant on-target toxicities exist. We explored the possibility... 
Medicine & Public Health | PLGA-microparticles | Mini-pumps | Oncology | Cancer Research | Therapeutic index | Pharmacology/Toxicology | Everolimus | MAMMALIAN TARGET | ADVANCED SOLID TUMORS | RAD001 EVEROLIMUS | ANTICANCER ACTIVITY | PHARMACOKINETICS | ONCOLOGY | PATHWAY | IN-VIVO | Minipumps | TUMOR-BEARING RODENTS | PHARMACOLOGY & PHARMACY | EXPOSURE | MTOR INHIBITOR | Lactic Acid - chemistry | Drug Administration Schedule | Administration, Oral | Humans | Biological Availability | Everolimus - administration & dosage | Antineoplastic Agents - administration & dosage | Breast Neoplasms - drug therapy | Antineoplastic Agents - toxicity | Xenograft Model Antitumor Assays | Animals | Everolimus - pharmacokinetics | Mice, Nude | Polyglycolic Acid - chemistry | Inhibitory Concentration 50 | Everolimus - toxicity | Female | Antineoplastic Agents - pharmacokinetics | Mice | Chromatography, Liquid - methods | Kidney Neoplasms - drug therapy | Tandem Mass Spectrometry - methods | Models | Blood cell count | Analysis | Cancer | Animal models | Low concentrations | Toxicity | Syngeneic grafts | Body weight | Blood | Microparticles | Powder | Polylactide-co-glycolide | Allografts | Rodents | Animal tissues | Xenografts | Bioindicators | Drug dosages | Dosing | Effectiveness | Kidneys | Blood cells | Oral administration | Bioavailability | Protein arrays | Equivalence | Biomarkers | Tumors | Plasmas (physics) | Kidney transplantation | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 3934 - 3934
Journal Article
Journal Article
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 08/2016, Volume 7, Issue 8, pp. 735 - 740
Oncogenic MLL fusion proteins aberrantly recruit Dot1L, a histone methyltransferase, to ectopic loci, leading to local hypermethylation of H3K79 and... 
protein structure-based design | mixed lineage leukemia | inhibitor | protein lysine methyltransferase | Dot1L | HISTONE METHYLTRANSFERASE DOT1L | PROTEIN METHYLTRANSFERASES | H3K79 METHYLATION | CELLS | CHEMISTRY, MEDICINAL | SELECTIVE INHIBITORS
Journal Article
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