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1. Full Text Expression of HLA-G by mast cells is associated with hepatitis C virus-induced liver fibrosis
by Amiot, Laurence and Vu, Nicolas and Rauch, Michel and L’Helgoualc’h, Annie and Chalmel, Frédéric and Gascan, Hugues and Turlin, Bruno and Guyader, Dominique and Samson, Michel
Journal of Hepatology, ISSN 0168-8278, 2013, Volume 60, Issue 2, pp. 245 - 252
Background & Aims Infection with hepatitis C virus is a worldwide health problem. An inadequate Th2 cytokine response promotes the fibrosis-cirrhosis fate.... 
Gastroenterology and Hepatology | IFN-α | Liver | Fibrosis | HCV | Mast cell | Hepatitis C | HLA-G | CHEMOTAXIS | CD4(+) T-CELLS | G MOLECULES | DISORDERS | HUMAN TROPHOBLASTS | INDUCTION | IFN-alpha | MESSENGER-RIBONUCLEIC-ACID | HUMAN CYTOMEGALOVIRUS-INFECTION | ANTIGEN-PRESENTING CELLS | GASTROENTEROLOGY & HEPATOLOGY | MODULATION | Immunohistochemistry | Liver Cirrhosis - immunology | Liver - pathology | Humans | Middle Aged | Male | Th2 Cells - immunology | Hepatitis C, Chronic - complications | Liver - immunology | Aged, 80 and over | Adult | Female | HLA-G Antigens - genetics | Cytokines - genetics | Liver Cirrhosis - genetics | Interferon-alpha - metabolism | Liver Cirrhosis - etiology | Mast Cells - immunology | Gene Expression | Chemokines - genetics | Disease Progression | Mast Cells - pathology | Hepatitis C, Chronic - immunology | Aged | Hepatitis C, Chronic - genetics | HLA-G Antigens - metabolism | Virus diseases | Histocompatibility antigens | HLA histocompatibility antigens | Hepatitis C virus | Health aspects | Liver cirrhosis | Life Sciences | Human health and pathology | Infectious diseases
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2. Full Text Selected Alkylating Agents Can Overcome Drug Tolerance of G(0)-like Tumor Cells and Eradicate BRCA1-Deficient Mammary Tumors in Mice
by Pajic, M and Blatter, S and Guyader, C and Gonggrijp, M and Kersbergen, A and Kucukosmanoglu, A and Sol, W and Drost, R and Jonkers, J and Borst, P and Rottenberg, S
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 11/2017, Volume 23, Issue 22, pp. 7020 - 7033
Purpose: We aimed to characterize and target drug-tolerant BRCA1-deficient tumor cells that cause residual disease and subsequent tumor relapse. Experimental... 
BREAST-CANCER | REPAIR | THERAPY | CISPLATIN | ONCOLOGY | DNA | RESISTANCE | ANTICANCER DRUGS | BRCA1 | INDUCTION | CHEMOTHERAPY
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3. Full Text Selected Alkylating Agents Can Overcome Drug Tolerance of G 0 -like Tumor Cells and Eradicate BRCA1-Deficient Mammary Tumors in Mice
by Pajic, Marina and Blatter, Sohvi and Guyader, Charlotte and Gonggrijp, Maaike and Kersbergen, Ariena and Küçükosmanoğlu, Aslι and Sol, Wendy and Drost, Rinske and Jonkers, Jos and Borst, Piet and Rottenberg, Sven
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 11/2017, Volume 23, Issue 22, p. 7020
We aimed to characterize and target drug-tolerant BRCA1-deficient tumor cells that cause residual disease and subsequent tumor relapse. We studied responses to... 
Humans | Antineoplastic Agents, Alkylating - pharmacology | Cisplatin - pharmacology | Breast Neoplasms - drug therapy | Mice, Knockout | Dose-Response Relationship, Drug | Nimustine - pharmacology | Drug Resistance, Neoplasm - genetics | Genes, p53 | Animals | Breast Neoplasms - genetics | Resting Phase, Cell Cycle - genetics | Breast Neoplasms - pathology | Breast Neoplasms - mortality | Female | Resting Phase, Cell Cycle - drug effects | Mice | Genes, BRCA1 | Disease Models, Animal
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4. Full Text Global surveillance of cancer survival 1995–2009: analysis of individual data for 25 676 887 patients from 279 population-based registries in 67 countries (CONCORD-2)
by Allemani, Claudia, PhD and Weir, Hannah K, PhD and Carreira, Helena, MPH and Harewood, Rhea, MSc and Spika, Devon, MSc and Wang, Xiao-Si, PhD and Bannon, Finian, PhD and Ahn, Jane V, MSc and Johnson, Christopher J, MPH and Bonaventure, Audrey, MD and Marcos-Gragera, Rafael, PhD and Stiller, Charles, MSc and Azevedo e Silva, Gulnar, Prof and Chen, Wan-Qing, PhD and Ogunbiyi, Olufemi J, Prof and Rachet, Bernard, FFPH and Soeberg, Matthew J, PhD and You, Hui, MAppStats and Matsuda, Tomohiro, PhD and Bielska-Lasota, Magdalena, Prof and Storm, Hans, MD and Tucker, Thomas C, Prof and Coleman, Michel P, Prof and CONCORD Working Grp and CONCORD Working Group
Lancet, The, ISSN 0140-6736, 2015, Volume 385, Issue 9972, pp. 977 - 1010
Summary Background Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of... 
Internal Medicine | BREAST-CANCER | MEDICINE, GENERAL & INTERNAL | RECTAL-CANCER | CHILDHOOD-CANCER | BENCHMARKING PARTNERSHIP | EUROPE 1999-2007 | HIGH-RESOLUTION | NORDIC COUNTRIES | OVARIAN-CANCER | NET SURVIVAL | HIGH-INCOME COUNTRIES | Age Distribution | Global Health | Humans | Middle Aged | Child, Preschool | Neoplasms - mortality | Infant | Male | Young Adult | Adolescent | Survival Analysis | Aged, 80 and over | Sex Distribution | Adult | Female | Registries | Aged | Child | Infant, Newborn | Prevention | Patient outcomes | Analysis | Cancer | Medical research | Global health | Survival analysis | Surveillance | Mortality | Population | Medical and Health Sciences | Medicin och hälsovetenskap | Mathematics | Klinisk medicin | Natural Sciences | Sannolikhetsteori och statistik | Probability Theory and Statistics | Clinical Medicine | Naturvetenskap | Neoplasms/mortality | Cancer and Oncology | Matematik | Cancer och onkologi
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5. Full Text Ledipasvir-sofosbuvir with or without ribavirin to treat patients with HCV genotype 1 infection and cirrhosis non-responsive to previous protease-inhibitor therapy: a randomised, double-blind, phase 2 trial (SIRIUS)
by Bourlière, Marc, Dr and Bronowicki, Jean-Pierre, MD and de Ledinghen, Victor, MD and Hézode, Christophe, MD and Zoulim, Fabien, MD and Mathurin, Philippe, MD and Tran, Albert, MD and Larrey, Dominique G, MD and Ratziu, Vlad, MD and Alric, Laurent, MD and Hyland, Robert H, DPhil and Jiang, Deyuan, PhD and Doehle, Brian, PhD and Pang, Phillip S, MD and Symonds, William T, PharmD and Subramanian, G Mani, MD and McHutchison, John G, MD and Marcellin, Patrick, MD and Habersetzer, François, MD and Guyader, Dominique, MD and Grangé, Jean-Didier, MD and Loustaud-Ratti, Véronique, MD and Serfaty, Lawrence, MD and Metivier, Sophie, MD and Leroy, Vincent, MD and Abergel, Armand, MD and Pol, Stanislas, MD
Lancet Infectious Diseases, The, ISSN 1473-3099, 2015, Volume 15, Issue 4, pp. 397 - 404
Summary Background Patients with cirrhosis resulting from chronic hepatitis C virus (HCV) infection are at risk of life-threatening complications, but... 
Infectious Disease | SUSTAINED VIROLOGICAL RESPONSE | FIBROSIS | INFECTIOUS DISEASES | TREATMENT-NAIVE | TELAPREVIR | HEPATITIS-C VIRUS | PLUS SOFOSBUVIR | ACCESS PROGRAM | TREATMENT-EXPERIENCED PATIENTS | PEGYLATED INTERFERON | BOCEPREVIR | Humans | Middle Aged | Fluorenes - therapeutic use | Hepacivirus - genetics | Hepatitis C, Chronic - virology | Male | RNA, Viral - blood | Hepatitis C, Chronic - complications | Viral Load | Young Adult | Adult | Female | France | Placebos - administration & dosage | Benzimidazoles - therapeutic use | Uridine Monophosphate - therapeutic use | Hepacivirus - isolation & purification | Liver Cirrhosis - drug therapy | Double-Blind Method | Antiviral Agents - therapeutic use | Ribavirin - therapeutic use | Genotype | Treatment Outcome | Hepatitis C, Chronic - drug therapy | Liver Cirrhosis - virology | Uridine Monophosphate - analogs & derivatives | Adolescent | Aged | Hepacivirus - classification | Care and treatment | Proteases | Clinical trials | Product development | Genetic aspects | Hepatitis C virus | Hepatitis C | Health aspects | Liver cirrhosis | Ribavirin | Genotype & phenotype | Liver cancer | Interferon | Mortality | Life Sciences
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6. Full Text The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways
by Li, Yang and Liu, Ying and Fu, Yujian and Wei, Taotao and Le Guyader, Laurent and Gao, Ge and Liu, Ru-Shi and Chang, Yan-Zhong and Chen, Chunying
Biomaterials, ISSN 0142-9612, 2011, Volume 33, Issue 2, pp. 402 - 411
Abstract With the development of nanotechnology and the wide use of graphene, it has become necessary to assess the potential biological adverse effects of... 
Advanced Basic Science | Dentistry | Mitogen activated protein kinase | TGF-beta | Graphene | Apoptosis | Macrophage | CELLS | OXIDATIVE STRESS | MATERIALS SCIENCE, BIOMATERIALS | OXIDE | G/M ARREST | ENGINEERING, BIOMEDICAL | TRANSDUCTION | CARBON NANOTUBES | TITANIUM-DIOXIDE PARTICLES | MICE | GROWTH-FACTOR | MEMBRANE PERMEABILIZATION | Cell Line | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | bcl-2-Associated X Protein - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Membrane Potential, Mitochondrial - drug effects | Blotting, Western | Macrophages - metabolism | Animals | MAP Kinase Signaling System - genetics | Transforming Growth Factor beta - genetics | Caspase 3 | Macrophages - drug effects | Mice | Mice, Inbred BALB C | Graphite - pharmacology | Real-Time Polymerase Chain Reaction | Transforming Growth Factor beta - metabolism | Biological products | Graphite | Genetic research | Biological apparatus and supplies | Bone morphogenetic proteins | Macrophages
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7. Full Text Worldwide comparison of ovarian cancer survival: Histological group and stage at diagnosis (CONCORD-2)
by Matz, Melissa and Coleman, Michel P and Carreira, Helena and Salmerón, Diego and Chirlaque, Maria Dolores and Allemani, Claudia and CONCORD Working Grp and CONCORD Working Group
Gynecologic Oncology, ISSN 0090-8258, 2016, Volume 144, Issue 2, pp. 396 - 404
Abstract Objective Ovarian cancer comprises several histological groups with widely differing levels of survival. We aimed to explore international variation... 
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | epidemiology | stage | morphology | histology | ovarian cancer | survival | POPULATION | OBSTETRICS & GYNECOLOGY | PATHOGENESIS | EUROPE | ORIGIN | COUNTRY | ONCOLOGY | Humans | Middle Aged | Adolescent | Ovarian Neoplasms - pathology | Aged, 80 and over | Adult | Female | Aged | Ovarian Neoplasms - mortality | Neoplasm Staging | Comparative analysis | Diagnosis | Ovarian cancer | Epidemiology | Analysis
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8. Full Text Worldwide comparison of survival from childhood leukaemia for 1995–2009, by subtype, age, and sex (CONCORD-2): a population-based study of individual data for 89 828 children from 198 registries in 53 countries
by Bonaventure, Audrey, Dr and Harewood, Rhea, MSc and Stiller, Charles A, MSc and Gatta, Gemma, MD and Clavel, Jacqueline, MD and Stefan, Daniela C, MD and Carreira, Helena, MSc and Spika, Devon, MSc and Marcos-Gragera, Rafael, PhD and Peris-Bonet, Rafael, Prof and Piñeros, Marion, MD and Sant, Milena, MD and Kuehni, Claudia E, MD and Murphy, Michael F G, MSc and Coleman, Michel P, Prof and Allemani, Claudia, PhD and CONCORD Working Grp and CONCORD Working Group
The Lancet Haematology, ISSN 2352-3026, 2017, Volume 4, Issue 5, pp. e202 - e217
Summary Background Global inequalities in access to health care are reflected in differences in cancer survival. The CONCORD programme was designed to assess... 
Hematology, Oncology and Palliative Medicine | CANCER SURVIVAL | GLOBAL BURDEN | EUROPE | MORTALITY | MIDDLE-INCOME COUNTRIES | ABANDONMENT | ADOLESCENTS | HEMATOLOGY | Healthcare Disparities - statistics & numerical data | Hematologic Neoplasms - mortality | Humans | Child, Preschool | Neoplasms - mortality | Infant | Male | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Leukemia, Myeloid, Acute - mortality | Adolescent | Survival Analysis | Female | Registries | Healthcare Disparities - trends | Child | Research Design | Infant, Newborn | Leukemia | Leucèmia en els infants | Leukemia in children | Leucèmia | Life Sciences | Hematologic Neoplasms/mortality | Medical and Health Sciences | Medicin och hälsovetenskap | Leukemia, Myeloid, Acute/mortality | Klinisk medicin | Healthcare Disparities/statistics & numerical data | Clinical Medicine | Precursor Cell Lymphoblastic Leukemia-Lymphoma/mortality | Neoplasms/mortality | Cancer and Oncology | Cancer och onkologi
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