Breast Cancer Research and Treatment, ISSN 0167-6806, 8/2019, Volume 176, Issue 3, pp. 495 - 506
Clinical trials investigating therapies for metastatic breast cancer (mBC) generally use progression-free survival (PFS) as primary endpoint, which is not...
Medicine & Public Health | Surrogate validation | Surrogate threshold effect | Oncology | Breast neoplasms | Overall survival | Progression-free survival | 1ST-LINE TREATMENT | SOLID TUMORS | ENDOCRINE THERAPY | PHASE-III TRIAL | GROWTH-FACTOR RECEPTOR | EXEMESTANE | ONCOLOGY | FULVESTRANT | DOUBLE-BLIND | POSTMENOPAUSAL WOMEN | AROMATASE INHIBITORS | Antimitotic agents | Medical research | Care and treatment | Patient outcomes | Medicine, Experimental | Development and progression | Breast cancer | Metastasis | Hormones | Tamoxifen | Antineoplastic agents | Cancer | Review
Medicine & Public Health | Surrogate validation | Surrogate threshold effect | Oncology | Breast neoplasms | Overall survival | Progression-free survival | 1ST-LINE TREATMENT | SOLID TUMORS | ENDOCRINE THERAPY | PHASE-III TRIAL | GROWTH-FACTOR RECEPTOR | EXEMESTANE | ONCOLOGY | FULVESTRANT | DOUBLE-BLIND | POSTMENOPAUSAL WOMEN | AROMATASE INHIBITORS | Antimitotic agents | Medical research | Care and treatment | Patient outcomes | Medicine, Experimental | Development and progression | Breast cancer | Metastasis | Hormones | Tamoxifen | Antineoplastic agents | Cancer | Review
Journal Article
Plant Physiology, ISSN 0032-0889, 9/2013, Volume 163, Issue 1, pp. 43 - 60
Plant phenolics have drawn increasing attention due to their potential nutritional benefits. Although the basic reactions of the phenolics biosynthetic...
Quantitative trait loci | Lignin | Enzymes | Flavonoids | Metabolites | Genes | Biosynthesis | Plants | BIOCHEMISTRY AND METABOLISM | Genotypes | Fruits | FRAGARIA-X-ANANASSA | OCTOPLOID STRAWBERRY | SPECIES REVEALS | PHENOLIC-COMPOUNDS | CULTIVATED STRAWBERRY | GENE-EXPRESSION ANALYSIS | ANTIOXIDANT CAPACITY | CLASS-III PEROXIDASES | NUTRITIONAL QUALITY | DNA MICROARRAYS | PLANT SCIENCES | Amino Acid Sequence | Oligonucleotide Array Sequence Analysis | Plant Proteins - physiology | Down-Regulation | Color | Molecular Sequence Data | Peroxidase - physiology | Anthocyanins - biosynthesis | Biosynthetic Pathways | Fruit - enzymology | Gene Expression Profiling | Acyltransferases - metabolism | Acyltransferases - genetics | Plant Proteins - genetics | Sequence Alignment | Lignin - biosynthesis | Fragaria - enzymology | Peroxidase - genetics | Plant Proteins - metabolism | Quantitative Trait Loci | Peroxidase - metabolism | Anthocyanin | Strawberries | Physiological aspects | Peroxidase | Research
Quantitative trait loci | Lignin | Enzymes | Flavonoids | Metabolites | Genes | Biosynthesis | Plants | BIOCHEMISTRY AND METABOLISM | Genotypes | Fruits | FRAGARIA-X-ANANASSA | OCTOPLOID STRAWBERRY | SPECIES REVEALS | PHENOLIC-COMPOUNDS | CULTIVATED STRAWBERRY | GENE-EXPRESSION ANALYSIS | ANTIOXIDANT CAPACITY | CLASS-III PEROXIDASES | NUTRITIONAL QUALITY | DNA MICROARRAYS | PLANT SCIENCES | Amino Acid Sequence | Oligonucleotide Array Sequence Analysis | Plant Proteins - physiology | Down-Regulation | Color | Molecular Sequence Data | Peroxidase - physiology | Anthocyanins - biosynthesis | Biosynthetic Pathways | Fruit - enzymology | Gene Expression Profiling | Acyltransferases - metabolism | Acyltransferases - genetics | Plant Proteins - genetics | Sequence Alignment | Lignin - biosynthesis | Fragaria - enzymology | Peroxidase - genetics | Plant Proteins - metabolism | Quantitative Trait Loci | Peroxidase - metabolism | Anthocyanin | Strawberries | Physiological aspects | Peroxidase | Research
Journal Article
Plant Cell, Tissue and Organ Culture (PCTOC), ISSN 0167-6857, 6/2013, Volume 113, Issue 3, pp. 375 - 385
Hydroxyphenylpyruvate reductase (HPPR) and rosmarinic acid synthase (RAS) have been described as enzymes involved in rosmarinic acid (RA) biosynthesis. In this...
Life Sciences | Plant Pathology | Hydroxyphenylpyruvate reductase | RNAi | Overexpression | Rosmarinic acid synthase | Rosmarinic acid | Plant Physiology | Coleus blumei | Plant Sciences | Plant Genetics & Genomics | HYDROXYCINNAMOYL-COA | CELL-CULTURES | PLANT SCIENCES | CHALCONE SYNTHASE | INTEGRATION | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SUSPENSION-CULTURES | PURIFICATION | ACYLTRANSFERASES | PLANTS | DEPENDENT HYDROXYPYRUVATE REDUCTASE | Genetic research | Physiological aspects | Enzymes | Genetic engineering | Genes | Viroids | Reductases | Hairy root | Transformation | Acids | Transcription | RNA-mediated interference | Biosynthesis | Reductase
Life Sciences | Plant Pathology | Hydroxyphenylpyruvate reductase | RNAi | Overexpression | Rosmarinic acid synthase | Rosmarinic acid | Plant Physiology | Coleus blumei | Plant Sciences | Plant Genetics & Genomics | HYDROXYCINNAMOYL-COA | CELL-CULTURES | PLANT SCIENCES | CHALCONE SYNTHASE | INTEGRATION | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SUSPENSION-CULTURES | PURIFICATION | ACYLTRANSFERASES | PLANTS | DEPENDENT HYDROXYPYRUVATE REDUCTASE | Genetic research | Physiological aspects | Enzymes | Genetic engineering | Genes | Viroids | Reductases | Hairy root | Transformation | Acids | Transcription | RNA-mediated interference | Biosynthesis | Reductase
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 05/2016, Volume 64, Issue 18, pp. 3688 - 3696
The strawberry fruit proteins Fra a 1.01E–1.08 are homologues of the major birch pollen allergen Bet v 1. Three of the proteins are known to have essential...
allergen | flow cytometry | Fragaria × ananassa | Bet v 1-like strawberry allergen | basophil activation test (BAT) | CONTACT URTICARIA | FOOD ALLERGENS | Fragaria x ananassa | FOOD SCIENCE & TECHNOLOGY | BIRCH POLLEN ALLERGEN | FLAVONOID BIOSYNTHESIS | AGRICULTURE, MULTIDISCIPLINARY | CROSS-REACTIVITY | GENE-EXPRESSION | WOODLAND STRAWBERRY | CHEMISTRY, APPLIED | PROTEINS | BINDING | BASOPHIL ACTIVATION TEST | Fruit - immunology | Humans | Middle Aged | Molecular Sequence Data | Male | Antigens, Plant - chemistry | Young Adult | Food Hypersensitivity - immunology | Immunoglobulin E - immunology | Allergens - immunology | Plant Proteins - chemistry | Protein Isoforms - chemistry | Allergens - chemistry | Adult | Female | Fragaria - chemistry | Fruit - genetics | Amino Acid Sequence | Skin Tests | Fruit - chemistry | Antigens, Plant - immunology | Plant Proteins - immunology | Allergens - genetics | Fragaria - immunology | Antigens, Plant - genetics | Cross Reactions | Plant Proteins - genetics | Sequence Alignment | Fragaria - genetics | Protein Isoforms - immunology | Protein Isoforms - genetics
allergen | flow cytometry | Fragaria × ananassa | Bet v 1-like strawberry allergen | basophil activation test (BAT) | CONTACT URTICARIA | FOOD ALLERGENS | Fragaria x ananassa | FOOD SCIENCE & TECHNOLOGY | BIRCH POLLEN ALLERGEN | FLAVONOID BIOSYNTHESIS | AGRICULTURE, MULTIDISCIPLINARY | CROSS-REACTIVITY | GENE-EXPRESSION | WOODLAND STRAWBERRY | CHEMISTRY, APPLIED | PROTEINS | BINDING | BASOPHIL ACTIVATION TEST | Fruit - immunology | Humans | Middle Aged | Molecular Sequence Data | Male | Antigens, Plant - chemistry | Young Adult | Food Hypersensitivity - immunology | Immunoglobulin E - immunology | Allergens - immunology | Plant Proteins - chemistry | Protein Isoforms - chemistry | Allergens - chemistry | Adult | Female | Fragaria - chemistry | Fruit - genetics | Amino Acid Sequence | Skin Tests | Fruit - chemistry | Antigens, Plant - immunology | Plant Proteins - immunology | Allergens - genetics | Fragaria - immunology | Antigens, Plant - genetics | Cross Reactions | Plant Proteins - genetics | Sequence Alignment | Fragaria - genetics | Protein Isoforms - immunology | Protein Isoforms - genetics
Journal Article
Plant Physiology, ISSN 0032-0889, 9/2013, Volume 163, Issue 1, pp. 43 - 60
Metabolite profiling and quantitative genetics analyses uncover a strawberry peroxidase gene as an important factor controlling the flux to soluble...
Biochemistry and Metabolism
Biochemistry and Metabolism
Journal Article
Phytochemistry, ISSN 0031-9422, 2009, Volume 70, Issue 15, pp. 1663 - 1679
Enzymes of rosmarinic acid biosynthesis are discussed and compared to enzymes involved in the formation of chlorogenic acid and caffeoylshikimate. Rosmarinic...
CYP98A | Rosmarinic acid | Chlorogenic acid | Caffeoylshikimic acid | Acyltransferase | Phenylpropanoid metabolism | HYDROXYCINNAMOYL-COA | COLEUS-BLUMEI | TYROSINE AMINOTRANSFERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FUNCTIONAL-CHARACTERIZATION | HYDROXYPHENYLPYRUVATE REDUCTASE | CELL-CULTURES | LITHOSPERMUM-ERYTHRORHIZON | PLANT SCIENCES | SUBSTRATE-SPECIFICITY | CAFFEIC ACID | Shikimic Acid - chemistry | Depsides - metabolism | Cytochrome P-450 Enzyme System - metabolism | Depsides - chemistry | Shikimic Acid - metabolism | Acyltransferases - metabolism | Acyltransferases - genetics | Plants - enzymology | Plants - metabolism | Shikimic Acid - analogs & derivatives | Plants - genetics | Chlorogenic Acid - metabolism | Cinnamates - metabolism | Cytochrome P-450 Enzyme System - genetics | Molecular Structure | Cinnamates - chemistry | Evolution, Molecular
CYP98A | Rosmarinic acid | Chlorogenic acid | Caffeoylshikimic acid | Acyltransferase | Phenylpropanoid metabolism | HYDROXYCINNAMOYL-COA | COLEUS-BLUMEI | TYROSINE AMINOTRANSFERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FUNCTIONAL-CHARACTERIZATION | HYDROXYPHENYLPYRUVATE REDUCTASE | CELL-CULTURES | LITHOSPERMUM-ERYTHRORHIZON | PLANT SCIENCES | SUBSTRATE-SPECIFICITY | CAFFEIC ACID | Shikimic Acid - chemistry | Depsides - metabolism | Cytochrome P-450 Enzyme System - metabolism | Depsides - chemistry | Shikimic Acid - metabolism | Acyltransferases - metabolism | Acyltransferases - genetics | Plants - enzymology | Plants - metabolism | Shikimic Acid - analogs & derivatives | Plants - genetics | Chlorogenic Acid - metabolism | Cinnamates - metabolism | Cytochrome P-450 Enzyme System - genetics | Molecular Structure | Cinnamates - chemistry | Evolution, Molecular
Journal Article
Journal of Berry Research, ISSN 1878-5093, 2013, Volume 3, Issue 4, pp. 197 - 201
Journal Article
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