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Annals of the Rheumatic Diseases, ISSN 0003-4967, 04/2017, Volume 76, Issue 4, pp. 773 - 778
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 2018, Volume 17, Issue 8, pp. 588 - 606
Danger signals are a hallmark of many common inflammatory diseases, and these stimuli can function to activate the cytosolic innate immune signalling receptor... 
GASDERMIN D | IL-1-BETA SECRETION | DENDRITIC CELLS | BAY 11-7082 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | AMYLOID-BETA | ACTIVATION DOWNSTREAM | PHARMACOLOGY & PHARMACY | MURINE MODELS | NF-KAPPA-B | HUMAN MONOCYTES | NALP3 INFLAMMASOME | NLRP3 | Care and treatment | Inflammation | Models | Research | Inflammatory diseases
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2013, Volume 110, Issue 50, pp. 20224 - 20229
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2013, Volume 110, Issue 50, p. 20224
  Wnt signaling is one of the key oncogenic pathways in multiple cancers, and targeting this pathway is an attractive therapeutic approach. However,... 
Molecules | Phosphorylation | Membranes | Inhibitor drugs | Breast cancer | Gene expression
Journal Article
NATURE REVIEWS DRUG DISCOVERY, ISSN 1474-1776, 09/2018, Volume 17, Issue 9, p. 688
This corrects the article DOI: 10.1038/nrd.2018.97. 
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PHARMACOLOGY & PHARMACY
Journal Article
Organic Geochemistry, ISSN 0146-6380, 05/2010, Volume 41, Issue 5, p. 482
We investigated the stable carbon and hydrogen isotopic signatures of methane, CO.sub.2 and water during microbial formation of methane from mineral... 
Methane | Biogeochemistry | Analysis | Fatty acids | Aquifers
Journal Article
Organic Geochemistry, ISSN 0146-6380, 05/2010, Volume 41, Issue 5, pp. 482 - 490
We investigated the stable carbon and hydrogen isotopic signatures of methane, CO sub(2) and water during microbial formation of methane from mineral... 
Journal Article
Organic Geochemistry, ISSN 0146-6380, 2010, Volume 41, Issue 5, pp. 482 - 490
We investigated the stable carbon and hydrogen isotopic signatures of methane, CO and water during microbial formation of methane from mineral oil-related... 
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 09/2018, Volume 17, Issue 9, pp. 688 - 688
Journal Article
Nature Communications, ISSN 2041-1723, 10/2015, Volume 6, Issue 1, p. 8372
Journal Article
Nature Communications, 10/2015, Volume 6, p. 8372
  Insufficient pancreatic β-cell mass or function results in diabetes mellitus. While significant progress has been made in regulating insulin secretion from... 
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, p. e0131071
Emerging approaches to treat immune disorders target positive regulatory kinases downstream of antigen receptors with small molecule inhibitors. Here we... 
STIM1 | MULTIDISCIPLINARY SCIENCES | T-CELL-ACTIVATION | 1,4,5-TRISPHOSPHATE 3-KINASE B | PORE SUBUNIT | ORAI1 | DEATH | 1,3,4,5-TETRAKISPHOSPHATE | SELECTION | MICE LACKING | CRAC CHANNEL | Autoimmune Diseases - enzymology | Calcium Channels - metabolism | Apoptosis - drug effects | Jurkat Cells | Humans | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Rats, Inbred Lew | Apoptosis - genetics | ORAI1 Protein | Mice, Knockout | Phosphotransferases (Alcohol Group Acceptor) - metabolism | CD4-Positive T-Lymphocytes - immunology | Gene Expression Regulation - drug effects | Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors | Animals | Calcium Signaling - drug effects | HEK293 Cells | Autoimmune Diseases - therapy | Protein Kinase Inhibitors - pharmacology | Calcium Signaling - genetics | Inositol Phosphates - metabolism | Autoimmune Diseases - pathology | CD4-Positive T-Lymphocytes - drug effects | Inositol | Calcium channels | B cells | T cells | Phosphotransferases | Phosphates | Calcium | Genomics | STIM1 protein | Lymphocytes T | Arthritis | Activation | Kinases | Calcium signalling | Receptors | Cell activation | Clonal deletion | Lymphocytes | Deletion | Inhibition | Immune system | Antigens | Calcium (intracellular) | T cell receptors | Pharmacology | Gene expression | Orai1 protein | Molecular chains | Inhibitors | FasL protein | Cell death | Respiratory diseases | Intracellular | Receptor mechanisms | Autoimmune diseases | Endoplasmic reticulum | BIM protein | Calcium ions | Apoptosis | Pharmaceuticals
Journal Article
CLIMATE OF THE PAST, ISSN 1814-9324, 2016, Volume 12, Issue 3, pp. 713 - 727
Clay mineral assemblages in a sediment core from the distal Nile discharge plume off Israel have been used to reconstruct the late Quaternary Nile sediment... 
MEDITERRANEAN SEA | AEGEAN SEA | GEOSCIENCES, MULTIDISCIPLINARY | LATE QUATERNARY | CELL PROVENANCE | SURFACE SEDIMENTS | NORTHERN ISRAEL | HUMID PERIOD | SAPROPEL FORMATION | LATE PLEISTOCENE | METEOROLOGY & ATMOSPHERIC SCIENCES | CLAY MINERAL DISTRIBUTIONS
Journal Article
Cancer Research, ISSN 0008-5472, 02/2016, Volume 76, Issue 3 Supplement, pp. IA35 - IA35
Journal Article
Organic Geochemistry, ISSN 0146-6380, 05/2010, Volume 41, Issue 5, pp. 482 - 490
We investigated the stable carbon and hydrogen isotopic signatures of methane, CO and water during microbial formation of methane from mineral oil-related... 
CRUDE-OIL BIODEGRADATION | GEOCHEMISTRY & GEOPHYSICS | IN-SITU BIODEGRADATION | ANAEROBIC OXIDATION | CONTAMINATED AQUIFER | ACETATE FERMENTATION | CARBON-ISOTOPE | FATTY-ACIDS | ECKERNFORDE BAY | SULFATE-REDUCING BACTERIA | N-ALKANES
Journal Article