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Journal Article
Nature, ISSN 0028-0836, 01/2012, Volume 481, Issue 7381, pp. 380 - 384
Journal Article
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 2011, Volume 7, Issue 1, pp. 523 - n/a
Oncogenes such as K‐ras mediate cellular and metabolic transformation during tumorigenesis. To analyze K‐Ras‐dependent metabolic alterations, we employed 13C... 
cancer | metabolism | transcriptional analysis | metabolic flux analysis | Ras | MOUSE FIBROBLASTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIAL METABOLISM | TRANSFORMED FIBROBLASTS | LINES | P53 | FLUX ANALYSIS | DATABASE | AEROBIC GLYCOLYSIS | GENE-EXPRESSION | MUTATIONS | Neoplasms - metabolism | NIH 3T3 Cells | Cell Proliferation | Gas Chromatography-Mass Spectrometry | Oligonucleotide Array Sequence Analysis | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Gene Expression Regulation, Neoplastic | Glutamine - metabolism | Gene Expression Profiling | Flow Cytometry | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Isotope Labeling | Fibroblasts - metabolism | Proto-Oncogene Proteins p21(ras) - metabolism | Cell Transformation, Neoplastic - metabolism | Citric Acid Cycle | Animals | Cell Line, Tumor | Glucose - metabolism | Glycolysis | Fibroblasts - cytology | Mice | Neoplasms - pathology | Cell Line, Transformed | Tricarboxylic acid cycle | Biotechnology | Reactive oxygen species | Transformation | Profiling | Transcription | Change detection | Downstream effects | Oxidative metabolism | Genes | Amino acids | Intracellular signalling | Pyruvic acid | Biosynthesis | Myc protein | Glucose | Kinases | Proteins | Glucose metabolism | Mitochondria | Metabolic flux | Alterations | Metabolites | Stable isotopes | Carbon 13 | Fluctuations | Adenine | Tumor cell lines | Fluxes | Metabolism | Nutrient uptake | Gene expression | Nitrogen | Carbon | Intermediates | Carbon cycle | Organic chemistry | Decoupling | Computer applications | Intracellular | Lactic acid | Apoptosis | Tracers | Glutamine | Cancer | System effectiveness
Journal Article
Immunity, ISSN 1074-7613, 04/2017, Volume 46, Issue 4, pp. 675 - 689
Activated T cells produce reactive oxygen species (ROS), which trigger the antioxidative glutathione (GSH) response necessary to buffer rising ROS and prevent... 
Gclc | glutathione | Myc | glycolysis | reactive oxygen species | ROS | mTOR | metabolism | T cells | GSH | metabolic reprogramming | NFAT | MAMMALIAN TARGET | CANCER-CELLS | GLUTAMINE REQUIREMENT | RECEPTOR STIMULATION | SIGNALING PATHWAY | LYMPHOCYTE ACTIVATION | C-MYC | COMPLEX 1 | INDUCED DEATH | IMMUNOLOGY | KINASE ACTIVATION | Reactive Oxygen Species - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Glutamate-Cysteine Ligase - deficiency | TOR Serine-Threonine Kinases - metabolism | Glutathione - metabolism | Mice, Inbred C57BL | NFATC Transcription Factors - metabolism | Glutamine - metabolism | Immunoblotting | Signal Transduction - genetics | Proto-Oncogene Proteins c-myc - metabolism | Mice, Knockout | Inflammation - metabolism | Animals | T-Lymphocytes - metabolism | Glycolysis | Inflammation - genetics | Glutamate-Cysteine Ligase - genetics | Encephalomyelitis, Autoimmune, Experimental - genetics | Energy Metabolism - genetics | Antiviral agents | Glucose metabolism | Cysteine | Thiols | Ligases | Physiological aspects | Glutamate | Cells | Inflammation | TOR protein | Transcription factors | Phosphorylation | Homeostasis | Lymphocytes T | Myc protein | NF-AT protein | Antiinfectives and antibacterials | Cell activation | Energy utilization | Cell growth | Gene targeting | Lymphocytes | Cell cycle | Physiology | Glutathione | Antigens | Integration | Rapamycin | T cell receptors | Metabolism | Ablation | Apoptosis
Journal Article
Analytical Chemistry, ISSN 0003-2700, 05/2009, Volume 81, Issue 9, pp. 3429 - 3439
Journal Article
Movement Disorders, ISSN 0885-3185, 05/2018, Volume 33, Issue 5, pp. 856 - 856
Journal Article
Journal Article