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Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2005, Volume 15, Issue 20, pp. 4555 - 4559
An SAR study of psilocybin and psilocin derivatives reveals that 1-methylpsilocin is a selective agonist at the h5-HT 2C receptor. The corresponding phosphate... 
Animals | Humans | Serotonin Receptor Agonists - chemistry | Mice | Structure-Activity Relationship | Serotonin 5-HT2 Receptor Agonists | Psilocybin - chemistry | Psilocybin - pharmacology | Serotonin Receptor Agonists - pharmacology
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 01/2006, Volume 49, Issue 1, pp. 135 - 158
Compound 1 was previously reported to be a potent inhibitor of cPLA2α in both artificial monomeric substrate and cell-based assays. However, 1 was inactive in... 
ARACHIDONIC-ACID RELEASE | GASTROINTESTINAL TOXICITY | COLLAGEN-INDUCED ARTHRITIS | CHEMISTRY, MEDICINAL | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | LEUKOTRIENE RECEPTOR ANTAGONIST | CHRONIC ASTHMA | PLATELET-ACTIVATING-FACTOR | RANDOMIZED CONTROLLED-TRIAL | C-3 REDUCTIVE ALKYLATION | GROUP-IV
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2003, Volume 44, Issue 24, pp. 4589 - 4591
General indole C 3 reductive alkylation conditions have been developed. The scope of this reaction includes C 2 unsubstituted indoles, aryl and alkyl... 
CHEMISTRY, ORGANIC
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 10/2005, Volume 15, Issue 20, pp. 4555 - 4559
An SAR study of psilocybin and psilocin derivatives reveals that 1-methylpsilocin is a selective agonist at the h5-HT receptor. The corresponding phosphate... 
3-<2-(CYCLOALKYLAMINO)ETHYL>INDOL-4-OLS | CHEMISTRY, MEDICINAL | UND PSILOCIN | CHEMISTRY, ORGANIC | 5-HYDROXYTRYPTAMINE(2A) RECEPTORS | SEROTONIN | MICE | FENFLURAMINE | IDENTIFICATION | BINDING
Journal Article
11/2019
The invention provides carriers that enhance the absorption, half-life or bioavailability of therapeutic compounds. The carriers comprise targeting groups that... 
HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
02/2018
The invention provides carriers that enhance the absorption, half-life or bioavailability of therapeutic compounds. The carriers comprise targeting groups that... 
HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
09/2019
The invention provides non-hormonal vitamin D conjugated via the third carbon on the vitamin D backbone to parathyroid hormone (PTH) proteins that result in... 
HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
06/2019
The invention provides a parathyroid hormone (PTH) compound comprising a PTH peptide. The PTH compound has a significantly increased bioavailability or... 
HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
11/2018
The invention provides non-hormonal vitamin D conjugated via the third carbon on the vitamin D backbone to parathyroid hormone (PTH) proteins that result in... 
HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
09/2018
The invention provides carriers that enhance the absorption, half-life or bioavailability of therapeutic compounds. The carriers comprise targeting groups that... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
11/2017
Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the... 
METALLURGY | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS
Patent
05/2016
The invention provides carriers that enhance the absorption, half-life or bioavailability of therapeutic compounds. The carriers comprise targeting groups that... 
HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
03/2016
The invention provides carriers that enhance the absorption, half-life or bioavailability of therapeutic compounds. The carriers comprise targeting groups that... 
HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
10/2017
The invention provides non-hormonal vitamin D conjugated to therapeutic RNA compounds that result in the compounds having increased absorption, bioavailability... 
NUCLEOTIDES | HYGIENE | METALLURGY | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | DERIVATIVES THEREOF | NUCLEOSIDES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES | SUGARS | NUCLEIC ACIDS
Patent
11/2015
The invention provides carriers that enhance the absorption, half-life or bioavailability of Ghrelin peptides. The carriers comprise targeting groups that bind... 
HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
08/2017
The invention provides non-hormonal vitamin D conjugated to apelin proteins that result in increased absorption, bioavailability or circulating half-life when... 
HYGIENE | METALLURGY | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES | ACYCLIC OR CARBOCYCLIC COMPOUNDS
Patent
06/2018
The invention provides non-hormonal vitamin D conjugated via the third carbon on the vitamin D backbone to parathyroid hormone (PTH) proteins that result in... 
HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
07/2017
The invention provides carriers that enhance the absorption, half-life or bioavailability of therapeutic compounds. The carriers comprise targeting groups that... 
HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
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