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Journal Article
PLoS ONE, ISSN 1932-6203, 01/2016, Volume 11, Issue 1, p. e0147230
It has been reported that inhibition of RAD52 either by specific shRNA or a small peptide aptamer induced synthetic lethality in tumor cell lines carrying... 
CELLS | REPAIR | DOMAIN | PROTEIN | ENRICHED FRAGMENT LIBRARIES | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | KINASE | BREAKS | LETHAL | CANCER | Small Molecule Libraries - pharmacology | DNA, Single-Stranded - metabolism | Humans | Models, Molecular | Germ-Line Mutation - genetics | Breast Neoplasms - drug therapy | BRCA1 Protein - genetics | Rad52 DNA Repair and Recombination Protein - chemistry | Breast Neoplasms - genetics | Rad52 DNA Repair and Recombination Protein - metabolism | Breast Neoplasms - pathology | Female | Protein Conformation | Molecular Docking Simulation | Tumor Cells, Cultured | BRCA1 Protein - deficiency | Physiological aspects | Genetic aspects | Breast cancer | Research | BRCA mutations | DNA-ligand interactions | Phosphates | Drugs | Carcinoma | Molecular structure | Peptides | Single-stranded DNA | Laboratories | Homologous recombination | Homology | Lethality | Drug development | Kinases | DNA repair | Molecular docking | Proteins | Immunology | Cell cycle | Inhibition | Deoxyribonucleic acid--DNA | Rad52 protein | Binding | BRCA2 protein | Medical research | AMP | BRCA1 protein | Research & development--R&D | Feasibility studies | FDA approval | Tumor cell lines | Medical screening | Medicine | Pharmacy | Aptamers | In vivo methods and tests | Mutation | Molecular biology | Binding sites | Cancer | Tumors | Research & development | Deoxyribonucleic acid | R&D | DNA
Journal Article
Journal Article
Journal Article
Angewandte Chemie, International Edition, ISSN 1433-7851, 2007, Volume 46, Issue 39, pp. 7485 - 7487
Journal Article
Journal Article
Blood, ISSN 0006-4971, 08/2013, Volume 122, Issue 7, pp. 1293 - 1304
Homologous recombination repair (HRR) protects cells from the lethal effect of spontaneous and therapy-induced DNA double-stand breaks. HRR usually depends on... 
GENOMIC INSTABILITY | STEM-CELLS | REPAIR | DNA-DAMAGE | IMATINIB | BREAKS | MYELOID-LEUKEMIA | SELF-RENEWAL | HOMOLOGOUS RECOMBINATION | HEMATOLOGY | CANCER | Peptide Fragments | Cell Proliferation | Oligonucleotide Array Sequence Analysis | Humans | Aptamers, Peptide - chemistry | Gene Expression Profiling | DNA Repair - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Case-Control Studies | Neoplasm Recurrence, Local - pathology | Neoplastic Stem Cells - metabolism | Rad52 DNA Repair and Recombination Protein - metabolism | BRCA1 Protein - metabolism | Biomarkers, Tumor - metabolism | DNA Damage - genetics | Neoplastic Stem Cells - pathology | Recombination, Genetic - genetics | Cell Differentiation | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Rad51 Recombinase - metabolism | Epigenomics | Neoplasm Recurrence, Local - prevention & control | Rad51 Recombinase - genetics | RNA, Messenger - genetics | Models, Molecular | Leukemia, Lymphocytic, Chronic, B-Cell - prevention & control | Mice, SCID | Mutation - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Rad52 DNA Repair and Recombination Protein - genetics | Xenograft Model Antitumor Assays | BRCA1 Protein - genetics | Fusion Proteins, bcr-abl - genetics | Rad52 DNA Repair and Recombination Protein - antagonists & inhibitors | Animals | BRCA2 Protein - metabolism | Aptamers, Peptide - pharmacology | Neoplasm Recurrence, Local - genetics | Biomarkers, Tumor - genetics | Mice | BRCA2 Protein - genetics | Fusion Proteins, bcr-abl - metabolism | Apoptosis | Index Medicus | Abridged Index Medicus | Myeloid Neoplasia
Journal Article
Journal of General Internal Medicine, ISSN 0884-8734, 4/2019, Volume 34, Issue 4, pp. 591 - 597
Journal Article
Vaccine, ISSN 0264-410X, 01/2018, Volume 36, Issue 5, pp. 668 - 674
Journal Article
by Gatsonis, Constantine A and Aberle, Denise R and Berg, Christine D and Black, William C and Church, Timothy R and Fagerstrom, Richard M and Galen, Barbara and Gareen, Ilana F and Goldin, Jonathan and Gohagan, John K and Hillman, Bruce and Jaffe, Carl and Kramer, Barnett S and Lynch, David and Marcus, Pamela M and Schnall, Mitchell and Sullivan, Daniel C and Sullivan, Dorothy and Zylak, Carl J and Cagnon, Christopher and Cody, Dianna and Fletcher, Glenn and Flynn, Michael J and Judy, Philip F and Kruger, Randell and Larke, Frederick J and McNitt-Gray, Michael and Payne, Thomas and Anthony Seibert, J and Wu, Xizeng and Abbott, Gerald and Amorosa, Judith K and Barr, Richard G and Boiselle, Phillip M and Chiles, Caroline and Clark, Robert and Coppage, Lynn and Falk, Robert and Fishman, Elliot K and Gemmel, David and Goldin, Jonathan G and Goodman, Eric and Hart, Eric M and Hazelton, Todd and Johnson, Elizabeth and Kazerooni, Ella and McComb, Barbara and McLennan, Geoffrey and Munden, Reginald F and Ravenel, James and Sullivan, Michael and Swensen, Stephen J and Torigian, Drew A and Vydareny, Kay H and Worrell, John A and Balkin, Peter and Fouad, Mona and Freedman, Matthew T and Garg, Kavita and Gelmann, Edward P and Gierada, David S and Hocking, William and Inampudi, Subbarao and Isaacs, Claudine and Kvale, Paul and Mann, Howard and Manor, William and Nath, Hrudaya and Reding, Douglas and Spizarny, David L and Strollo, Diane C and Waltz, John and Chen, Mei-Hsiu and Duan, Fenghai and Izmirilian, Grant and Pinsky, Paul and Prorok, Philip C and Miller, Anthony B and Edelman, Martin J and Evans, William K and Fontana, Robert S and Machtay, Mitchell and Clark, Kenneth W and Clingan, Kathy L and Ford, Melissa B and Márquez, Guillermo and Moore, Steven M and Ohan, Peter and Payne, Thomas J and Peace, Steven and Rosenbaum, Jennifer L and Barr, Richard and Black, William and Torigian, Drew and Vydareny, Kay and Worrell, John and Young, Robert C and Alberts, David and DeMets, David and Greenwald, Peter and ... and Natl Lung Screening Trial Res Team and National Lung Screening Trial Research Team
Radiology, ISSN 0033-8419, 01/2011, Volume 258, Issue 1, pp. 243 - 253
Journal Article