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by Northcott, Paul A and Shih, David J. H and Peacock, John and Garzia, Livia and Sorana Morrissy, A and Zichner, Thomas and Stútz, Adrian M and Korshunov, Andrey and Reimand, Júri and Schumacher, Steven E and Beroukhim, Rameen and Ellison, David W and Marshall, Christian R and Lionel, Anath C and MacK, Stephen and Dubuc, Adrian and Yao, Yuan and Ramaswamy, Vijay and Luu, Betty and Rolider, Adi and Cavalli, Florence M. G and Wang, Xin and Remke, Marc and Wu, Xiaochong and Chiu, Readman Y. B and Chu, Andy and Chuah, Eric and Corbett, Richard D and Hoad, Gemma R and Jackman, Shaun D and Li, Yisu and Lo, Allan and Mungall, Karen L and Ming Nip, Ka and Qian, Jenny Q and Raymond, Anthony G. J and Thiessen, Nina and Varhol, Richard J and Birol, Inanc and Moore, Richard A and Mungall, Andrew J and Holt, Robert and Kawauchi, Daisuke and Roussel, Martine F and Kool, Marcel and Jones, David T. W and Witt, Hendrick and Fernandez-L, Africa and Kenney, Anna M and Wechsler-Reya, Robert J and Dirks, Peter and Aviv, Tzvi and Grajkowska, Wieslawa A and Perek-Polnik, Marta and Haberler, Christine C and Delattre, Olivier and Reynaud, Stéphanie S and Doz, François F and Pernet-Fattet, Sarah S and Cho, Byung-Kyu and Kim, Seung-Ki and Wang, Kyu-Chang and Scheurlen, Wolfram and Eberhart, Charles G and Fèvre-Montange, Michelle and Jouvet, Anne and Pollack, Ian F and Fan, Xing and Muraszko, Karin M and Yancey Gillespie, G and Di Rocco, Concezio and Massimi, Luca and Michiels, Erna M. C and Kloosterhof, Nanne K and French, Pim J and Kros, Johan M and Olson, James M and Ellenbogen, Richard G and Zitterbart, Karel and Kren, Leos and Thompson, Reid C and Cooper, Michael K and Lach, Boleslaw and McLendon, Roger E and Bigner, Darell D and Fontebasso, Adam and Albrecht, Steffen and Jabado, Nada and Lindsey, Janet C and Bailey, Simon and Gupta, Nalin and Weiss, William A and Bognár, László and Klekner, Almos and Van Meter, Timothy E and Kumabe, Toshihiro and Tominaga, Teiji and Elbabaa, Samer K and Leonard, Jeffrey R and Rubin, Joshua B and ...
Nature, ISSN 0028-0836, 08/2012, Volume 487, Issue 7409, pp. 49 - 56
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 01/2006, Volume 76, Issue 2, pp. 105 - 109
Inhibition of tyrosine kinase (TK) receptors by synthetic small molecules has become a promising new therapy option in oncology. The TK inhibitor imatinib... 
targeted therapy | β | glioblastoma | Medicine & Public Health | c-kit | Oncology | platelet-derived growth factor receptor-α | c-abl and arg | Platelet-derived growth factor receptor-α | Targeted therapy | Glioblastoma | CHRONIC MYELOGENOUS LEUKEMIA | GLIOMAS | platelet-derived growth factor receptor-alpha , -beta | CLINICAL NEUROLOGY | CHRONIC MYELOID-LEUKEMIA | CHROMOSOME | MESSENGER-RNA | FLUORESCENCE | ONCOLOGY | TYROSINE KINASE INHIBITOR | STEM-CELL FACTOR | GASTROINTESTINAL STROMAL TUMORS | EXPRESSION | Immunohistochemistry | Predictive Value of Tests | Homeodomain Proteins - metabolism | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Proto-Oncogene Proteins c-kit - metabolism | Brain Neoplasms - metabolism | Patient Selection | Adult | Female | Glioblastoma - metabolism | Receptor, Platelet-Derived Growth Factor beta - metabolism | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Piperazines - therapeutic use | Brain Neoplasms - drug therapy | Enzyme Inhibitors - therapeutic use | Imatinib Mesylate | Adaptor Proteins, Signal Transducing | Pyrimidines - therapeutic use | Receptors, Platelet-Derived Growth Factor - metabolism | Survival Analysis | Proto-Oncogene Proteins c-abl - metabolism | Aged | Benzamides | Glioblastoma - drug therapy | Cohort Studies | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
by Sturm, Dominik and Orr, Brent A and Toprak, Umut H and Hovestadt, Volker and Jones, David T.W and Jones, Chris and Capper, David and Sill, Martin and Buchhalter, Ivo and Northcott, Paul A and Leis, Irina and Ryzhova, Marina and Koelsche, Christian and Pfaff, Elke and Allen, Sariah J and Balasubramanian, Gnanaprakash and Worst, Barbara C and Pajtler, Kristian W and Brabetz, Sebastian and Johann, Pascal D and Sahm, Felix and Reimand, Jüri and Mackay, Alan and Carvalho, Diana M and Remke, Marc and Phillips, Joanna J and Perry, Arie and Cowdrey, Cynthia and Drissi, Rachid and Fouladi, Maryam and Giangaspero, Felice and Łastowska, Maria and Grajkowska, Wiesława and Scheurlen, Wolfram and Pietsch, Torsten and Hagel, Christian and Gojo, Johannes and Lötsch, Daniela and Berger, Walter and Slavc, Irene and Haberler, Christine and Jouvet, Anne and Holm, Stefan and Hofer, Silvia and Prinz, Marco and Keohane, Catherine and Fried, Iris and Mawrin, Christian and Scheie, David and Mobley, Bret C and Schniederjan, Matthew J and Santi, Mariarita and Buccoliero, Anna M and Dahiya, Sonika and Kramm, Christof M and von Bueren, André O and von Hoff, Katja and Rutkowski, Stefan and Herold-Mende, Christel and Frühwald, Michael C and Milde, Till and Hasselblatt, Martin and Wesseling, Pieter and Rößler, Jochen and Schüller, Ulrich and Ebinger, Martin and Schittenhelm, Jens and Frank, Stephan and Grobholz, Rainer and Vajtai, Istvan and Hans, Volkmar and Schneppenheim, Reinhard and Zitterbart, Karel and Collins, V. Peter and Aronica, Eleonora and Varlet, Pascale and Puget, Stephanie and Dufour, Christelle and Grill, Jacques and Figarella-Branger, Dominique and Wolter, Marietta and Schuhmann, Martin U and Shalaby, Tarek and Grotzer, Michael and van Meter, Timothy and Monoranu, Camelia-Maria and Felsberg, Jörg and Reifenberger, Guido and Snuderl, Matija and Forrester, Lynn Ann and Koster, Jan and Versteeg, Rogier and Volckmann, Richard and van Sluis, Peter and Wolf, Stephan and Mikkelsen, Tom and Gajjar, Amar and Aldape, Kenneth and Moore, Andrew S and Taylor, Michael D and ...
Cell, ISSN 0092-8674, 02/2016, Volume 164, Issue 5, pp. 1060 - 1072
Journal Article
by Capper, David and Jones, David T. W and Sill, Martin and Hovestadt, Volker and Schrimpf, Daniel and Sturm, Dominik and Koelsche, Christian and Sahm, Felix and Chavez, Lukas and Reuss, David E and Kratz, Annekathrin and Wefers, Annika K and Huang, Kristin and Pajtler, Kristian W and Schweizer, Leonille and Stichel, Damian and Olar, Adriana and Engel, Nils W and Lindenberg, Kerstin and Harter, Patrick N and Braczynski, Anne K and Plate, Karl H and Dohmen, Hildegard and Garvalov, Boyan K and Coras, Roland and Hölsken, Annett and Hewer, Ekkehard and Bewerunge-Hudler, Melanie and Schick, Matthias and Fischer, Roger and Beschorner, Rudi and Schittenhelm, Jens and Staszewski, Ori and Wani, Khalida and Varlet, Pascale and Pages, Melanie and Temming, Petra and Lohmann, Dietmar and Selt, Florian and Witt, Hendrik and Milde, Till and Witt, Olaf and Aronica, Eleonora and Giangaspero, Felice and Rushing, Elisabeth and Scheurlen, Wolfram and Geisenberger, Christoph and Rodriguez, Fausto J and Becker, Albert and Preusser, Matthias and Haberler, Christine and Bjerkvig, Rolf and Cryan, Jane and Farrell, Michael and Deckert, Martina and Hench, Jürgen and Frank, Stephan and Serrano, Jonathan and Kannan, Kasthuri and Tsirigos, Aristotelis and Brück, Wolfgang and Hofer, Silvia and Brehmer, Stefanie and Seiz-Rosenhagen, Marcel and Hänggi, Daniel and Hans, Volkmar and Rozsnoki, Stephanie and Hansford, Jordan R and Kohlhof, Patricia and Kristensen, Bjarne W and Lechner, Matt and Lopes, Beatriz and Mawrin, Christian and Ketter, Ralf and Kulozik, Andreas and Khatib, Ziad and Heppner, Frank and Koch, Arend and Jouvet, Anne and Keohane, Catherine and Mühleisen, Helmut and Mueller, Wolf and Pohl, Ute and Prinz, Marco and Benner, Axel and Zapatka, Marc and Gottardo, Nicholas G and Driever, Pablo Hernáiz and Kramm, Christof M and Müller, Hermann L and Rutkowski, Stefan and Von Hoff, Katja and Frühwald, Michael C and Gnekow, Astrid and Fleischhack, Gudrun and Tippelt, Stephan and Calaminus, Gabriele and Monoranu, Camelia-Maria and Perry, Arie and Jones, Chris and ...
Nature, ISSN 0028-0836, 03/2018, Volume 555, Issue 7697, pp. 469 - 474
Journal Article
Acta neuropathologica communications, ISSN 2051-5960, 08/2016, Volume 4, Issue 1, p. 88
Journal Article
Science, ISSN 0036-8075, 04/2018, Volume 360, Issue 6386, pp. 331 - 335
Journal Article
SpringerPlus, ISSN 2193-1801, 12/2014, Volume 3, Issue 1, pp. 1 - 9
Despite some progress in the treatment of glioblastoma, most patients experience tumor recurrence. Imatinib mesylate, a tyrosine kinase inhibitor of platelet... 
Tyrosine kinase | c-kit | Cytokine | Glioblastoma | Markers | c-Abl | c-Fms | Inatinib | Arg kinase | Platelet derived growth factor | Science, general | GROWTH-FACTOR-RECEPTOR | MULTIDISCIPLINARY SCIENCES | PHASE-II | CANCER | EGFR | ADJUVANT TEMOZOLOMIDE | MESYLATE | HETEROGENEITY | MALIGNANT GLIOMAS | RADIOTHERAPY
Journal Article
by Bertozzi, A. I and Munzer, C and Fouyssac, F and Andre, N and Boetto, S and Leblond, P and Bourdeaut, F and Dufour, C and Deshpande, R. K and Bhat, K. G and Mahalingam, S and Muscat, A and Cain, J and Ferguson, M and Popovski, D and Algar, E and Rossello, F. J and Jayasekara, S and Watkins, D. N and Hodge, J and Ashley, D and Hishii, M and Saito, M and Arai, H and Han, Z. Y and Richer, W and Lucchesi, C and Freneaux, P and Nicolas, A and Grison, C and Pierron, G and Delattre, O and Epari, S and TS, N and Gupta, T and Chinnaswamy, G and Sastri, J. G and Shetty, P and Moiyadi, A and Jalali, R and Fay-McClymont, T and Johnston, D and Janzen, L and Guger, S and Scheinemann, K and Fleming, A and Fryer, C and Hukin, J and Mabbott, D and Huang, A and Bouffet, E and Lafay-Cousin, L and Kawamura, A and Yamamoto, K and Nagashima, T and Bartelheim, K and Benesch, M and Buchner, J and Gerss, J and Hasselblatt, M and Kortmann, R.-D and Fleischack, G and Quiroga, E and Reinhard, H and Schneppenheim, R and Seeringer, A and Siebert, R and Timmermann, B and Warmuth-Metz, M and Schmid, I and Fruhwald, M. C and Kerl, K and Klingebiel, T and Al-Kofide, A and Khafaga, Y and Al-Hindi, H and Dababo, M and Ul-Haq, A and Anas, M and Barria, M. G and Siddiqui, K and Hassounah, M and Ayas, M and Al-Shail, E and Jeibmann, A and Eikmeier, K and Linge, A and Johann, P and Koos, B and Kool, M and Pfister, S. M and Paulus, W and Schuller, U and Junckerstorff, R and Rosenblum, M. K and Alassiri, A. H and Rossi, S and Gottardo, N and Toledano, H and Viscardi, E and ...
Neuro-Oncology, ISSN 1522-8517, 06/2014, Volume 16, Issue suppl 1, pp. i1 - i9
Journal Article
by Hoffman, L. M and Donson, A. M and Nakachi, I and Griesinger, A. M and Birks, D. K and Amani, V and Hemenway, M. S and Liu, A. K and Wang, M and Hankinson, T. C and Handler, M. H and Foreman, N. K and Zakrzewska, M and Zakrzewski, K and Fendler, W and Stefanczyk, L and Liberski, P. P and Massimino, M and Gandola, L and Ferroli, P and Valentini, L and Biassoni, V and Garre, M. L and Sardi, I and Genitori, L and Giussani, C and Massimi, L and Bertin, D and Mussano, A and Viscardi, E and Modena, P and Mastronuzzi, A and Barra, S and Scarzello, G and Cinalli, G and Peretta, P and Giangaspero, F and Boschetti, L and Schiavello, E and Calareso, G and Antonelli, M and Pecori, E and Di Meco, F and Migliorati, R and Taborelli, A and Witt, H and Sill, M and Wani, K and Mack, S. C and Capper, D and Pajtler, K and Lambert, S and Tzaridis, T and Milde, T and Northcott, P. A and Kulozik, A. E and Witt, O and Collins, V. P and Ellison, D. W and Taylor, M. D and Kool, M and Jones, D. T. W and Korshunov, A and Ken, A and Pfister, S. M and Makino, K and Nakamura, H and Kuroda, J.-i and Kuratsu, J.-i and Toledano, H and Margolin, Y and Ohali, A and Michowiz, S and Johann, P and Tabori, U and Walker, E and Hawkins, C and Taylor, M and Yaniv, I and Avigad, S and Hoffman, L and Plimpton, S. R and Stence, N. V and Vibhakar, R and Lourdusamy, A and Rahman, R and Ward, J and Rogers, H and Grundy, R and Punchihewa, C and Lee, R and Lin, T and Orisme, W and Dalton, J and Aronica, E and Smith, A and Gajjar, A and Onar, A and Pounds, S and Tatevossian, R and ...
Neuro-Oncology, ISSN 1522-8517, 06/2014, Volume 16, Issue suppl 1, pp. i17 - i25
Journal Article