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1. Full Text Progress in cancer diagnosis and therapy using new imaging technologies
by Habuchi, Tomonori
Drug Delivery System, ISSN 0913-5006, 12/2014, Volume 29, Issue 4, pp. 271 - 271
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2. Full Text Overall survival of first‐line axitinib in metastatic renal cell carcinoma: Japanese subgroup analysis from phase II study
by Oya, Mototsugu and Tomita, Yoshihiko and Fukasawa, Satoshi and Shinohara, Nobuo and Habuchi, Tomonori and Rini, Brian I and Fujii, Yosuke and Kamei, Yoichi and Umeyama, Yoshiko and Bair, Angel H and Uemura, Hirotsugu
Cancer Science, ISSN 1347-9032, 06/2017, Volume 108, Issue 6, pp. 1231 - 1239
Subgroup analyses of a randomized global phase II study of axitinib showed objective response rate of 66% and median progression‐free survival of 27.6 months... 
renal cell carcinoma | Antiangiogenic agent | Japanese | axitinib | clinical trial phase II | EFFICACY | SAFETY | SORAFENIB | TRIAL | KEY PREDICTIVE FACTORS | INTERFERON-ALPHA | ONCOLOGY | DOSE TITRATION | AXIS | Double-Blind Method | Humans | Middle Aged | Proportional Hazards Models | Male | Treatment Outcome | Kidney Neoplasms - mortality | Carcinoma, Renal Cell - mortality | Disease-Free Survival | Protein Kinase Inhibitors - therapeutic use | Aged, 80 and over | Adult | Axitinib | Female | Aged | Imidazoles - therapeutic use | Carcinoma, Renal Cell - drug therapy | Kidney Neoplasms - drug therapy | Indazoles - therapeutic use | Clinical trials | Carcinoma, Renal cell | Metastasis | Analysis | Patient outcomes | Cell survival | Research funding | Toxicity | Multivariate analysis | Patients | Metastases | Kidney cancer | Response rates | Blood pressure | Vascular endothelial growth factor | Drug dosages | Clear cell-type renal cell carcinoma | Index Medicus | Original
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3. Full Text Single Nucleotide Polymorphisms of microRNA Machinery Genes Modify the Risk of Renal Cell Carcinoma
by Yohei Horikawa and Christopher G. Wood and Hushan Yang and Hua Zhao and Yuanqing Ye and Jian Gu and Jie Lin and Tomonori Habuchi and Xifeng Wu
Clinical Cancer Research, ISSN 1078-0432, 12/2008, Volume 14, Issue 23, pp. 7956 - 7962
Purpose: MicroRNAs (miRNA) are a class of small noncoding RNA molecules that have been implicated in a wide variety of basic cellular functions through... 
molecular epidemiology | renal cell carcinoma | microRNA-machinery gene | cancer susceptibility | single nucleotide polymorphism | OVEREXPRESSION | COMPLEX | VARIANTS | ONCOLOGY | PROGNOSIS | ADENOCARCINOMA | SEQUENCE | DICER | EXPRESSION | HUMAN CANCER | Genetic Predisposition to Disease | Kidney Neoplasms - genetics | Humans | Middle Aged | Carcinoma, Renal Cell - genetics | Female | Genotype | Male | Risk | MicroRNAs - genetics | Polymorphism, Single Nucleotide
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4. Full Text MP29-14 MACROPHAGE INHIBITORY CYTOKINE-1 STIMULATES STROMAL CYTOKINE PRODUCTION IN HIGH-FAT DIET-INDUCED PROSTATE CANCER PROGRESSION
by Huang, Mingguo and Narita, Shintaro and Inoue, Takamitsu and Habuchi, Tomonori
The Journal of Urology, ISSN 0022-5347, 04/2018, Volume 199, Issue 4, pp. e371 - e371
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5. Current status of castration-resistant prostate cancer translational research
by Maeno, Atsushi and Habuchi, Tomonori
Nihon rinsho. Japanese journal of clinical medicine, ISSN 0047-1852, 01/2016, Volume 74, Issue 1, p. 40
Recently, new drugs including abiraterone and enzalutamide have been able to be used for castration resistant prostate cancer(CRPC) patients. However, a subset... 
Oncogene Proteins, Fusion - metabolism | Receptors, Glucocorticoid - antagonists & inhibitors | Receptors, Androgen - genetics | Neoplasm Invasiveness | Oncogene Proteins, Fusion - genetics | Humans | Receptors, Prostaglandin E, EP4 Subtype - antagonists & inhibitors | Male | Receptors, Glucocorticoid - metabolism | Translational Medical Research - methods | Prostatic Neoplasms, Castration-Resistant - genetics | Prostatic Neoplasms, Castration-Resistant - pathology
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6. Current status of castration-resistant prostate cancer translational research
by Maeno, Atsushi and Habuchi, Tomonori
Nihon rinsho. Japanese journal of clinical medicine, ISSN 0047-1852, 01/2016, Volume 74, Issue 1, pp. 40 - 44
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7. Full Text PD33-12 THE ROLE OF FATTY ACID BINDING PROTEIN 4 IN PROSTATE STROMAL TUMOR MICROENVIRONMENT AND PROSTATE CANCER PROGRESSION
by Huang, Mingguo and Koizumi, Atsushi and Inoue, Takamitsu and Narita, Shintaro and Habuchi, Tomonori
Journal of Urology, The, ISSN 0022-5347, 2017, Volume 197, Issue 4, pp. e598 - e598
Urology | Development and progression | Prostate cancer | Fatty acids | Tumors | Protein binding
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8. Laparoscopic radical nephrectomy : Standard method
by Habuchi, Tomonori
Japanese Journal of Clinical Urology, ISSN 0385-2393, 11/2012, Volume 66, Issue 12, pp. 931 - 940
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9. Full Text Origin of multifocal carcinomas of the bladder and upper urinary tract: Molecular analysis and clinical implications
by HABUCHI, TOMONORI
International Journal of Urology, ISSN 0919-8172, 08/2005, Volume 12, Issue 8, pp. 709 - 716
The simultaneous or metachronous development of multifocal tumors with identical or variable histological features in the urothelial tract in a single patient... 
molecular genetics | recurrence | multifocality | urothelial cancer | bladder cancer | Multifocality | Recurrence | Urothelial cancer | Molecular genetics | Bladder cancer | LONG-TERM | MICROSATELLITE ANALYSIS | SENSITIVE DETECTION | NATURAL-HISTORY | COMMON CLONAL ORIGIN | RANDOMIZED TRIAL | TRANSITIONAL-CELL-CARCINOMA | P53 GENE-MUTATIONS | UROLOGY & NEPHROLOGY | TRANSURETHRAL RESECTION | UROTHELIAL CARCINOMAS | Neoplasm Recurrence, Local - pathology | Neoplasms, Multiple Primary - genetics | Urinary Bladder Neoplasms - genetics | Humans | Urinary Bladder Neoplasms - pathology | Neoplasm Recurrence, Local - genetics | Neoplasms, Multiple Primary - pathology | Urothelium - pathology
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10. Full Text A novel strategy for evasion of NK cell immunity by tumours expressing core2 O- glycans
by Saitoh, Hisao and Horikawa, Yohei and Nakamura, Toshiya and Yamaya, Kanemitsu and Ohyama, Chikara and Habuchi, Tomonori and Funyu, Tomihisa and Hiraoka, Nobuyoshi and Hashimoto, Yasuhiro and Koie, Takuya and Sutoh, Mihoko and Hatakeyama, Shingo and Tsuboi, Shigeru and Yoneyama, Takahiro and Mori, Kazuyuki and Fukuda, Minoru
The EMBO Journal, ISSN 0261-4189, 08/2011, Volume 30, Issue 15, pp. 3173 - 3185
The O‐glycan branching enzyme, core2 β‐1,6‐N‐acetylglucosaminyltransferase (C2GnT), forms O‐glycans containing an N‐acetylglucosamine branch connected to... 
NKG2D | MICA | core2 O‐glycans | NK cell immunity | tumour metastasis | core2 O-glycans | BLADDER-CANCER | COMPLEX | MEDIATED CYTOTOXICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | ACTIVATING IMMUNORECEPTOR NKG2D | LIGANDS | POLYLACTOSAMINE | PROSTATE-CANCER | MICE | GALECTINS | PROGRESSION | Histocompatibility Antigens Class I - metabolism | Immune Evasion | NK Cell Lectin-Like Receptor Subfamily K - metabolism | Urinary Bladder Neoplasms - enzymology | Galectin 3 - metabolism | Urinary Bladder Neoplasms - immunology | Killer Cells, Natural - immunology | Urinary Bladder Neoplasms - chemistry | N-Acetylglucosaminyltransferases - metabolism | Polysaccharides - metabolism | Bladder | Enzymes | Metastasis | Molecular biology | Gene expression | Tumors
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11. Full Text Urological laparoendoscopic single‐site and reduced port surgery: A nationwide survey in Japan
by Narita, Mitsuhiro and Kageyama, Susumu and Okegawa, Takatsugu and Kinoshita, Hidefumi and Sato, Fuminori and Nakagawa, Ken and Habuchi, Tomonori and Hoshi, Akio and Matsubara, Akio and Yoshimura, Koji and Terachi, Toshiro and Mimata, Hiromitsu and Kawauchi, Akihiro
International Journal of Urology, ISSN 0919-8172, 03/2018, Volume 25, Issue 3, pp. 263 - 268
Objectives To evaluate the current status of urological laparoendoscopic single‐site and reduced port surgery in Japan. Methods Of the 152 institutions to... 
laparoendoscopic single‐site surgery | Japan | reduced port surgery | urology | laparoendoscopic single-site surgery | METAANALYSIS | INITIAL-EXPERIENCE | CONVENTIONAL LAPAROSCOPIC NEPHRECTOMY | UROLOGY & NEPHROLOGY | MULTIINSTITUTIONAL ANALYSIS | COMPLICATIONS | ADRENALECTOMY | Surveys | Surgery | Adrenalectomy | Laparoscopy | Nephrectomy
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12. Full Text MP73-18 SARCOPENIC OBESITY ASSOCIATED WITH ANDROGEN DEPRIVATION THERAPY IN PATIENTS WITH PROSTATE CANCER
by Mitsuzuka, Koji and Kyan, Atsushi and Orikasa, Kazuhiko and Sato, Tomonori and Miyazato, Minoru and Narita, Shintaro and Koie, Takuya and Habuchi, Tomonori and Ohyama, Chikara and Arai, Yoichi
Journal of Urology, The, ISSN 0022-5347, 2015, Volume 193, Issue 4, pp. e937 - e937
Urology | Obesity | Care and treatment | Cancer patients | Prostate cancer
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13. Common genetic polymorphisms and prognosis of sporadic cancers: Prostate cancer as a model
by Habuchi, Tomonori
Future Oncology, ISSN 1479-6694, 04/2006, Volume 2, Issue 2, pp. 233 - 245
To date, most molecular epidemiological studies on gene polymorphisms in cancer have focused on the risk of development and susceptibility to cancer. However,... 
Prognosis | Androgen | Genetics | Microenvironment | Prostate cancer | Growth factor | Polymorphism | Genetic Predisposition to Disease | Prostatic Neoplasms - genetics | Humans | Male | Prostatic Neoplasms - diagnosis | Neoplasm Proteins - genetics | Polymorphism, Genetic
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14. Full Text Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study
by Kote-Jarai, Zsofia and Olama, Ali Amin Al and Giles, Graham G and Severi, Gianluca and Schleutker, Johanna and Weischer, Maren and Campa, Daniele and Riboli, Elio and Key, Tim and Gronberg, Henrik and Hunter, David J and Kraft, Peter and Thun, Michael J and Ingles, Sue and Chanock, Stephen and Albanes, Demetrius and Hayes, Richard B and Neal, David E and Hamdy, Freddie C and Donovan, Jenny L and Pharoah, Paul and Schumacher, Fredrick and Henderson, Brian E and Stanford, Janet L and Ostrander, Elaine A and Sorensen, Karina Dalsgaard and Dörk, Thilo and Andriole, Gerald and Dickinson, Joanne L and Cybulski, Cezary and Lubinski, Jan and Spurdle, Amanda and Clements, Judith A and Chambers, Suzanne and Aitken, Joanne and Gardiner, R. A. Frank and Thibodeau, Stephen N and Schaid, Dan and John, Esther M and Maier, Christiane and Vogel, Walther and Cooney, Kathleen A and Park, Jong Y and Cannon-Albright, Lisa and Brenner, Hermann and Habuchi, Tomonori and Zhang, Hong-Wei and Lu, Yong-Jie and Kaneva, Radka and Muir, Ken and Benlloch, Sara and Leongamornlert, Daniel A and Saunders, Edward J and Tymrakiewicz, Malgorzata and Mahmud, Nadiya and Guy, Michelle and O'Brien, Lynne T and Wilkinson, Rosemary A and Hall, Amanda L and Sawyer, Emma J and Dadaev, Tokhir and Morrison, Jonathan and Dearnaley, David P and Horwich, Alan and Huddart, Robert A and Khoo, Vincent S and Parker, Christopher C and Van As, Nicholas and Woodhouse, Christopher J and Thompson, Alan and Christmas, Tim and Ogden, Chris and Cooper, Colin S and Lophatonanon, Aritaya and Southey, Melissa C and Hopper, John L and English, Dallas R and Wahlfors, Tiina and Tammela, Teuvo L. J and Klarskov, Peter and Nordestgaard, Børge G and Røder, M Andreas and Tybjarg-Hansen, Anne and Bojesen, Stig E and Travis, Ruth and Canzian, Federico and Kaaks, Rudolf and Wiklund, Fredrik and Aly, Markus and Lindstrom, Sara and Diver, W Ryan and Gapstur, Susan and Stern, Mariana C and Corral, Roman and Virtamo, Jarmo and Cox, Angela and Haiman, Christopher A and Le Marchand, Loic and Fitzgerald, Liesel and Kolb, Suzanne and ... and UK ProtecT Study Collaborators and Australian Prostate Canc BioResour and PRACTCTICAL Consortium and UK Genetic Prostate Canc Study Col and PRACTICAL Consortium and UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and UK ProtecT Study Collaborators, The Australian Prostate Cancer BioResource and The PRACTICAL Consortium and The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and The UK ProtecT Study Collaborators, The Australian Prostate Cancer BioResource
Nature Genetics, ISSN 1061-4036, 08/2011, Volume 43, Issue 8, pp. 785 - 791
Prostate cancer (PrCa) is the most frequently diagnosed male cancer in developed countries. We conducted a multi-stage genome-wide association study for PrCa... 
SEQUENCE VARIANTS | GENETICS & HEREDITY | Genome-Wide Association Study | Disease Susceptibility | Chromosomes, Human - genetics | Humans | Middle Aged | Genotype | Male | Case-Control Studies | Randomized Controlled Trials as Topic | Prostatic Neoplasms - genetics | Telomerase - genetics | Aged, 80 and over | Polymorphism, Single Nucleotide - genetics | Adult | Aged | Genome, Human | Cohort Studies | Disease susceptibility | Genomes | Genetic aspects | Research | Single nucleotide polymorphisms | Prostate cancer | Risk factors | Genetics | Gene loci | Regression analysis
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15. Full Text MP50-15 ASSOCIATION BETWEEN WEIGHT GAIN AND SARCOPENIC OBESITY IN PATIENTS WITH PROSTATE CANCER TREATED WITH ANDROGEN DEPRIVATION THERAPY
by Mitsuzuka, Koji and Kyan, Atsushi and Sato, Tomonori and Orikasa, Kazuhiko and Aoki, Hiroshi and Miyazato, Minoru and Narita, Shintaro and Koie, Takuya and Habuchi, Tomonori and Ohyama, Chikara and Arai, Yoichi
Journal of Urology, The, ISSN 0022-5347, 2016, Volume 195, Issue 4, pp. e678 - e678
Urology | Obesity | Care and treatment | Cancer patients | Prostate cancer
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16. Full Text Does androgen deprivation therapy impair renal function in patients with prostate cancer?
by Mitsuzuka, Koji and Kyan, Atsushi and Sato, Tomonori and Orikasa, Kazuhiko and Miyazato, Minoru and Kakoi, Narihiko and Narita, Shintaro and Koie, Takuya and Habuchi, Tomonori and Ohyama, Chikara and Arai, Yoichi and Tohoku Evidence-Based Medicine Study Group and Michinoku Urological Cancer Study Group
Journal of Clinical Oncology, ISSN 0732-183X, 01/2016, Volume 34, Issue 2_suppl, pp. 323 - 323
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17. Full Text Impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations and incidence of rejection in Japanese renal transplant recipients receiving different tacrolimus formulations
by Niioka, Takenori and Kagaya, Hideaki and Saito, Mitsuru and Inoue, Takamitsu and Numakura, Kazuyuki and Yamamoto, Ryohei and Habuchi, Tomonori and Satoh, Shigeru and Miura, Masatomo
Clinical and Experimental Nephrology, ISSN 1342-1751, 10/2017, Volume 21, Issue 5, pp. 787 - 796
We investigated the impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations (C 0h/D) and the incidence of rejection in... 
Rejection | Nephrology | Medicine & Public Health | Tacrolimus | Formulation | Renal transplantation | CYP3A5 genotype | Dose-adjusted trough concentration | Urology | POPULATION | DETERMINANTS | TWICE-DAILY TACROLIMUS | INTRAPATIENT VARIABILITY | PHARMACODYNAMICS | PHARMACOKINETICS | KIDNEY-TRANSPLANTATION | UROLOGY & NEPHROLOGY | ABCB1 POLYMORPHISMS | PHARMACOGENETICS | SINGLE NUCLEOTIDE POLYMORPHISMS | Japan - epidemiology | Multivariate Analysis | Calcineurin Inhibitors - pharmacokinetics | Humans | Immunosuppressive Agents - pharmacokinetics | Asian Continental Ancestry Group - genetics | Incidence | Calcineurin Inhibitors - blood | Drug Dosage Calculations | Immunosuppressive Agents - blood | Cytochrome P-450 CYP3A - genetics | Drug Compounding | Pharmacogenomic Variants | Odds Ratio | Immunosuppressive Agents - administration & dosage | Tacrolimus - administration & dosage | Pharmacogenetics | Calcineurin Inhibitors - administration & dosage | Graft Rejection - prevention & control | Risk Factors | Genotype | Logistic Models | Treatment Outcome | Tacrolimus - pharmacokinetics | Chi-Square Distribution | Tacrolimus - adverse effects | Calcineurin Inhibitors - adverse effects | Cytochrome P-450 CYP3A - metabolism | Graft Rejection - ethnology | Immunosuppressive Agents - adverse effects | Graft Rejection - immunology | Drug Monitoring | Graft Rejection - genetics | Graft Survival - drug effects | Kidney Transplantation - adverse effects | Kidneys | Analysis | Organ transplant recipients | Genetic aspects | Transplantation | Kidney diseases | Transplants & implants | Alleles | Health risk assessment | Gene polymorphism | Graft rejection | Kidney transplantation
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18. Full Text The impact of obesity and adiponectin signaling in patients with renal cell carcinoma: A potential mechanism for the "obesity paradox"
by Ito, Ryuichi and Narita, Shintaro and Huang, Mingguo and Nara, Taketoshi and Numakura, Kazuyuki and Takayama, Koichiro and Tsuruta, Hiroshi and Maeno, Atsushi and Saito, Mitsuru and Inoue, Takamitsu and Tsuchiya, Norihiko and Satoh, Shigeru and Habuchi, Tomonori
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, p. e0171615
Although obesity increases the risk of renal cell carcinoma (RCC), obese patients with RCC experience longer survival than non-obese patients. However, the... 
SURVIVAL | APOPTOSIS | MULTIDISCIPLINARY SCIENCES | BODY-MASS INDEX | RECEPTOR | PROLIFERATION | PROSTATE-CANCER PROGRESSION | EXPRESSION | SERUM ADIPONECTIN | Immunohistochemistry | Cell Proliferation | Humans | Middle Aged | Male | Young Adult | Aged, 80 and over | Adiponectin - metabolism | Adult | Female | Carcinoma, Renal Cell - etiology | Body Mass Index | Signal Transduction | Obesity - complications | Patient Outcome Assessment | Disease Progression | Obesity - metabolism | Adiponectin - blood | Carcinoma, Renal Cell - metabolism | Carcinoma, Renal Cell - diagnosis | Survival Analysis | Biomarkers | Carcinoma, Renal Cell - therapy | Cell Line, Tumor | Aged | Neoplasm Staging | Apoptosis | Obesity | Complications and side effects | Cellular proteins | Care and treatment | Development and progression | Genetic aspects | Cellular signal transduction | Carcinoma, Renal cell | Health aspects
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19. Full Text Increased fatty acyl saturation of phosphatidylinositol phosphates in prostate cancer progression
by Koizumi, A and Narita, S and Nakanishi, H and Ishikawa, M and Eguchi, S and Kimura, H and Takasuga, S and Huang, MG and Inoue, T and Sasaki, J and Yoshioka, T and Habuchi, T and Sasaki, T
SCIENTIFIC REPORTS, ISSN 2045-2322, 09/2019, Volume 9, Issue 1, pp. 1 - 8
Phosphoinositides (PIPs) participate in many cellular processes, including cancer progression; however, the metabolic features of PIPs associated with prostate... 
SUPPRESSOR | INPP4B | INHIBITION | DE-NOVO LIPOGENESIS | MULTIDISCIPLINARY SCIENCES | CELL-PROLIFERATION | ACID SYNTHASE | DECREASED EXPRESSION | Phosphoinositides | Phosphatidylinositol 3,4,5-triphosphate | Hyperplasia | Cell lines | Mass spectroscopy | Tumor cell lines | Phosphatidylinositol 4,5-diphosphate | Prostate cancer | PTEN protein | Phosphatidylinositol phosphates
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20. Full Text A comparison of laparoendoscopic single-site surgery versus conventional procedures for laparoscopic donor nephrectomy: a Japanese multi-institutional retrospective study
by Inoue, Takamitsu and Miura, Masayoshi and Yanishi, Masaaki and Furukawa, Junya and Sato, Fuminori and Nitta, Masahiro and Yoshimura, Koji and Hagiuda, Jun and Shinoda, Kazunobu and Kobayashi, Takashi and Miyajima, Akira and Nakagawa, Ken and Oya, Mototsugu and Ogawa, Osamu and Mimata, Hiromitsu and Kanayama, Hiro-omi and Fujisawa, Masato and Terachi, Toshiro and Matsuda, Tadashi and Habuchi, Tomonori and LESS and RPS Research Group in Japanese Society of Endourology
Surgical Endoscopy, ISSN 0930-2794, 09/2019
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