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British Journal of Clinical Pharmacology, ISSN 0306-5251, 04/2014, Volume 77, Issue 4, pp. 587 - 596
Journal Article
Journal Article
BioSpektrum, ISSN 0947-0867, 09/2010, Volume 16, Issue 5, pp. 527 - 529
Journal Article
Pharmacogenetics and Genomics, ISSN 1744-6872, 03/2012, Volume 22, Issue 3, pp. 198 - 205
Journal Article
European Journal of Clinical Pharmacology, ISSN 0031-6970, 4/2012, Volume 68, Issue 4, pp. 389 - 395
The cytotoxic drug cyclophosphamide (CP) is bioactivated into 4-hydroxy-cyclophosphamide (4-OH-CP) through cytochrome P450 enzymes and cleared through aldehyde... 
ALDH3A1 | Pharmacogenetics | Cyclophosphamide | Biomedicine | GSTA1 | Pharmacology/Toxicology | CYP2C19 | 4-Hydroxycyclophosphamide | POLYMORPHISMS | CYP2B6 | 4-HYDROXYCYCLOPHOSPHAMIDE | PHARMACOKINETICS | GLUTATHIONE | BIOACTIVATION | PHARMACOLOGY & PHARMACY | TOXICITY | PHARMACOGENETICS | CHEMOTHERAPY | IFOSFAMIDE ACTIVATION | Doxorubicin - therapeutic use | Cyclophosphamide - administration & dosage | Cyclophosphamide - analogs & derivatives | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antineoplastic Agents, Alkylating - administration & dosage | Cyclophosphamide - therapeutic use | Breast Neoplasms - metabolism | Fluorouracil - therapeutic use | Glutathione Transferase - genetics | Antineoplastic Agents, Alkylating - blood | Adult | Female | Leukocyte Count | Aldehyde Dehydrogenase - genetics | Genotype | Antineoplastic Agents, Alkylating - pharmacokinetics | Breast Neoplasms - drug therapy | Doxorubicin - pharmacokinetics | Cyclophosphamide - blood | Breast Neoplasms - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cytochrome P-450 Enzyme System - genetics | Aged | Cyclophosphamide - pharmacokinetics | Fluorouracil - pharmacokinetics | Women | Enzymes | Medical colleges | Care and treatment | Anthracyclines | Cytochrome P-450 | Breast cancer | Antineoplastic agents | Aldehydes | Biopharmaceutics | Antimitotic agents | Cancer patients | Chemotherapy | Glutathione transferase | Analysis | Universities and colleges | Health aspects | Cancer | Genotype & phenotype | Side effects | Pharmacology
Journal Article
Pharmacogenetics and Genomics, ISSN 1744-6872, 04/2008, Volume 18, Issue 4, pp. 357 - 365
OBJECTIVESTo evaluate whether ABCC2 gene polymorphisms are associated with expression and/or function of the efflux pump. METHODSWe investigated the allele... 
Multidrug resistance related protein 2 | Pharmacogenetics | Rifampicin | Talilonol | Induction | Membrane transport | rifampicin | HEALTHY JAPANESE SUBJECTS | multidrug resistance related protein 2 | FUNCTIONAL-CHARACTERIZATION | ORGANIC ANION-TRANSPORTER | P-GLYCOPROTEIN ABCB1 | SUBSTRATE-SPECIFICITY | induction | DRUG TRANSPORTERS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | talilonol | DUBIN-JOHNSON-SYNDROME | GENETICS & HEREDITY | membrane transport | PHARMACOLOGY & PHARMACY | RESISTANCE-ASSOCIATED PROTEIN-2 | pharmacogenetics | MRP2 ABCC2 | SINGLE NUCLEOTIDE POLYMORPHISMS | Intestines - drug effects | Nucleic Acid Synthesis Inhibitors - pharmacology | Humans | Antihypertensive Agents - administration & dosage | Biological Availability | Male | Intestines - metabolism | Propanolamines - pharmacokinetics | RNA, Messenger - metabolism | Membrane Transport Proteins - genetics | Duodenum - metabolism | Adult | Female | Membrane Transport Proteins - metabolism | Multidrug Resistance-Associated Proteins - genetics | Administration, Oral | Gene Frequency | RNA, Messenger - genetics | Genotype | Antihypertensive Agents - pharmacokinetics | DNA Primers | Reverse Transcriptase Polymerase Chain Reaction | Polymorphism, Single Nucleotide - genetics | Infusions, Intravenous | Propanolamines - administration & dosage | Rifampin - pharmacology | Multidrug Resistance-Associated Proteins - metabolism | Duodenum - drug effects
Journal Article
Pharmacological Reports, ISSN 1734-1140, 09/2015, Volume 67, pp. 21 - 21
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2015, Volume 77, pp. 127 - 140
Journal Article