Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (82) 82
Book / eBook (10) 10
Publication (7) 7
Reference (4) 4
Conference Proceeding (3) 3
Book Chapter (2) 2
Newspaper Article (2) 2
Dissertation (1) 1
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (40) 40
biochemistry & molecular biology (27) 27
cell biology (27) 27
chromosomes (25) 25
humans (19) 19
proteins (19) 19
animals (18) 18
adenosine triphosphatases - metabolism (17) 17
mitosis (17) 17
dna-binding proteins - metabolism (16) 16
multiprotein complexes - metabolism (16) 16
cohesin (15) 15
condensin (15) 15
yeast (14) 14
chromosomal proteins, non-histone - metabolism (13) 13
cell cycle proteins - metabolism (12) 12
models, molecular (12) 12
research (12) 12
cell division (11) 11
deoxyribonucleic acid--dna (11) 11
dna (11) 11
chromosomes - metabolism (10) 10
topoisomerase-ii (10) 10
chromosomal proteins, non-histone - chemistry (9) 9
chromosome segregation (9) 9
male (9) 9
saccharomyces cerevisiae proteins - metabolism (9) 9
saccharomyces-cerevisiae (9) 9
sister-chromatid cohesion (9) 9
article (8) 8
cells (8) 8
crystal-structure (8) 8
female (8) 8
genome (8) 8
medicine & public health (8) 8
saccharomyces cerevisiae - genetics (8) 8
saccharomyces cerevisiae - metabolism (8) 8
saccharomyces cerevisiae proteins - chemistry (8) 8
adenosine triphosphatases - chemistry (7) 7
architecture (7) 7
biology (7) 7
cell cycle proteins - chemistry (7) 7
chromatin (7) 7
chromosome condensation (7) 7
chromosomes - chemistry (7) 7
complex (7) 7
dna-binding proteins - chemistry (7) 7
fission yeast (7) 7
gene expression (7) 7
genomes (7) 7
internal medicine (7) 7
multidisciplinary sciences (7) 7
multiprotein complexes - chemistry (7) 7
nuclear proteins - chemistry (7) 7
nuclear proteins - metabolism (7) 7
protein binding (7) 7
protein structure, tertiary (7) 7
smc (7) 7
anaphase (6) 6
binding sites (6) 6
chromatids - metabolism (6) 6
chromosomes, fungal - metabolism (6) 6
dimerization (6) 6
dna-binding proteins - genetics (6) 6
dna-replication (6) 6
hydrolysis (6) 6
life sciences (6) 6
middle aged (6) 6
mitotic chromosome (6) 6
models, biological (6) 6
molecular biology (6) 6
physiological aspects (6) 6
segregation (6) 6
acetylation (5) 5
adenosine triphosphatase (5) 5
adenosine triphosphatases - genetics (5) 5
adenosine triphosphatases - physiology (5) 5
aged (5) 5
analysis (5) 5
budding yeast (5) 5
cell cycle proteins - genetics (5) 5
chromosomal proteins, non-histone - genetics (5) 5
cleavage (5) 5
dna-binding proteins - physiology (5) 5
follow-up studies (5) 5
genomics (5) 5
meiosis (5) 5
multiprotein complexes - genetics (5) 5
organization (5) 5
phosphorylation (5) 5
protein (5) 5
sister chromatids (5) 5
sister-chromatid separation (5) 5
smc proteins (5) 5
13s condensin (4) 4
abc atpase (4) 4
adenosine triphosphate - metabolism (4) 4
amino acid sequence (4) 4
articles (4) 4
biochemistry, genetics and molecular biology (4) 4
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Robarts - Stacks (5) 5
St. Augustine's Seminary - Stacks (4) 4
St. Michael's College (John M. Kelly) - 3rd Floor (4) 4
Pontifical Inst. Mediaeval Studies - Library use only (3) 3
Trinity College (John W Graham) - Stacks (3) 3
Art - Library use only (2) 2
Gerstein Science - Stacks (2) 2
Regis College - Stacks (2) 2
UTL at Downsview - May be requested (2) 2
Collection Dvlpm't (Acquisitions) - Vendor file (1) 1
Royal Ontario Museum - Stacks (1) 1
St. Michael's College (John M. Kelly) - 2nd Floor (1) 1
UofT at Mississauga - Stacks (1) 1
Victoria University E.J. Pratt - Stacks (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Twist to disentangle
by Bisht, S and Haering, CH
NATURE STRUCTURAL & MOLECULAR BIOLOGY, ISSN 1545-9993, 04/2019, Volume 26, Issue 4, pp. 252 - 253
Intertwining of DNA molecules frequently results in the formation of ‘ultrafine bridges’ between sister chromatids that need to be resolved during segregation... 
TOPOISOMERASE-II | BIOPHYSICS | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | CONDENSIN COMPLEX | PICH | REVEALS | CELL BIOLOGY | DNA topoisomerase I | Genetic aspects | Research | Genetic regulation | Helicases | DNA topoisomerase II | Bridges | DNA helicase | Sister chromatids | Chromatids | Ultrafines | Extrusion | Helices | Supercoiling | Topology | Deoxyribonucleic acid--DNA
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Structural Basis of an Asymmetric Condensin ATPase Cycle
by Hassler, Markus and Shaltiel, Indra A and Kschonsak, Marc and Simon, Bernd and Merkel, Fabian and Thärichen, Lena and Bailey, Henry J and Macošek, Jakub and Bravo, Sol and Metz, Jutta and Hennig, Janosch and Haering, Christian H
Molecular Cell, ISSN 1097-2765, 06/2019, Volume 74, Issue 6, pp. 1175 - 1188.e9
The condensin protein complex plays a key role in the structural organization of genomes. How the ATPase activity of its SMC subunits drives large-scale... 
condensin | cohesin | SMC protein complex | ABC ATPase | genome organization | mitotic chromosome | structural biology | DNA loop extrusion | MOLECULAR-REPLACEMENT | FULLY-AUTOMATIC CHARACTERIZATION | STRUCTURE REFINEMENT | DATA-COLLECTION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | COHESIN RING | CHROMOSOME CONDENSATION | PROTEIN COMPLEXES | CRYSTALLOGRAPHY | DNA EXIT GATE | CELL BIOLOGY | Proteins | Atoms | Genomics | Cells | Adenosine triphosphatase
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Solution structure and flexibility of the condensin HEAT-repeat subunit Ycg1
by Manalastas-Cantos, K and Kschonsak, M and Haering, CH and Svergun, DI
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 09/2019, Volume 294, Issue 37, pp. 13822 - 13829
High-resolution structural analysis of flexible proteins is frequently challenging and requires the synergistic application of different experimental... 
condensin | size exclusion chromatography with multiangle static light scattering (SEC-MALS) | SMALL-ANGLE SCATTERING | small-angle X-ray scattering (SAXS) | dynamic light scattering (DLS) | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA binding protein | COMPLEXES | oligomer | X-RAY-SCATTERING | protein flexibility | conformational change | DNA | HEAT-repeat | structural model | CONFERS
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Cohesin: Its roles and mechanisms
by Nasmyth, Kim and Haering, Christian H
Annual Review of Genetics, ISSN 0066-4197, 12/2009, Volume 43, Issue 1, pp. 525 - 558
The cohesin complex is a major constituent of interphase and mitotic chromosomes. Apart from its role in mediating sister chromatid cohesion, it is also... 
Meiosis | Sister chromatid cohesion | ABC ATPase | Mitosis | Structural maintenance of chromosomes (Smc) | Chromosome segregation | SISTER-CHROMATID COHESION | XENOPUS EGG EXTRACTS | ANAPHASE-PROMOTING COMPLEX | meiosis | structural maintenance of chromosomes (Smc) | DOUBLE-STRAND BREAKS | PROTEIN PHOSPHATASE 2A | mitosis | SACCHAROMYCES-CEREVISIAE | chromosome segregation | sister chromatid cohesion | DAMAGE-INDUCED COHESION | MEIOSIS-I DEPENDS | GENETICS & HEREDITY | DE-LANGE-SYNDROME | SPINDLE-ASSEMBLY CHECKPOINT | Animals | Chromosomal Proteins, Non-Histone - metabolism | Models, Biological | Humans | Cell Cycle Proteins - metabolism | Chromosomes - metabolism | DNA - metabolism | Phosphorylation | Proteolysis | Analysis | Research | Chromosomes | DNA repair
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Distinct Roles for Condensin’s Two ATPase Sites in Chromosome Condensation
by Elbatsh, Ahmed M.O and Kim, Eugene and Eeftens, Jorine M and Raaijmakers, Jonne A and van der Weide, Robin H and García-Nieto, Alberto and Bravo, Sol and Ganji, Mahipal and uit de Bos, Jelmi and Teunissen, Hans and Medema, René H and de Wit, Elzo and Haering, Christian H and Dekker, Cees and Rowland, Benjamin D
Molecular Cell, ISSN 1097-2765, 12/2019, Volume 76, Issue 5, pp. 724 - 737.e5
Condensin is a conserved SMC complex that uses its ATPase machinery to structure genomes, but how it does so is largely unknown. We show that condensin’s... 
condensin | cohesin | SMC complexes | ABC ATPase | DNA loop extrusion | chromosome condensation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Two independent modes of chromatin organization revealed by cohesin removal
by Schwarzer, Wibke and Abdennur, Nezar and Goloborodko, Anton and Pekowska, Aleksandra and Fudenberg, Geoffrey and Loe-Mie, Yann and Fonseca, Nuno A and Huber, Wolfgang and Haering, Christian H and Mirny, Leonid and Spitz, Francois
Nature, ISSN 0028-0836, 11/2017, Volume 551, Issue 7678, pp. 51 - 56
Imaging and chromosome conformation capture studies have revealed several layers of chromosome organization, including segregation into megabase-sized active... 
HUMAN GENOME | MAPS | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | CRE RECOMBINASE | ARCHITECTURE | DYNAMICS | REORGANIZATION | TOPOLOGICAL DOMAINS | CTCF BINDING | PRINCIPLES | Chromosome Positioning | Chromatin - metabolism | Chromosomal Proteins, Non-Histone - metabolism | Epigenesis, Genetic | Liver - metabolism | Transcription Factors - deficiency | Cell Cycle Proteins - metabolism | Transcription Factors - genetics | Transcription Factors - metabolism | Animals | Transcription, Genetic | Enhancer Elements, Genetic - genetics | Mice | Chromatin - genetics | Chromatin - chemistry | Physiological aspects | Epigenetic inheritance | Chromatin | Observations | Cohesion | Enhancers | Clonal deletion | Transcription | Liver | Genomes | Cohesin | Gene expression | Chromosomes | Conformation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text The structure and function of SMC and kleisin complexes
by Nasmyth, Kim and Haering, Christian H
Annual Review of Biochemistry, ISSN 0066-4154, 2005, Volume 74, Issue 1, pp. 595 - 648
Protein complexes consisting of structural maintenance of chromosomes (SMC) and kleisin subunits are crucial for the faithful segregation of chromosomes during... 
Structural maintenance of chromosomes | Cohesin | MukB | ABC ATPase | Condensin | SISTER-CHROMATID COHESION | XENOPUS EGG EXTRACTS | FISSION YEAST | condensin | MITOTIC CHROMOSOME ARCHITECTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | STRAND-BREAK REPAIR | ESCHERICHIA-COLI | CELL-CYCLE CONTROL | SACCHAROMYCES-CEREVISIAE | cohesin | MEIOSIS-I DEPENDS | structural maintenance of chromosomes | UBIQUITOUS PROTEIN FAMILY | Fungal Proteins - chemistry | Cell Proliferation | Mitosis | Bacterial Proteins - chemistry | Multiprotein Complexes - genetics | Cell Cycle Proteins - chemistry | DNA-Binding Proteins - metabolism | Multiprotein Complexes - metabolism | Cell Cycle Proteins - genetics | Chromosomes - metabolism | Nuclear Proteins - genetics | Chromosomal Proteins, Non-Histone - metabolism | Bacterial Proteins - genetics | Cell Cycle Proteins - metabolism | Adenosine Triphosphatases - metabolism | Models, Molecular | Nuclear Proteins - metabolism | Fungal Proteins - genetics | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Chromosomal Proteins, Non-Histone - genetics | Multiprotein Complexes - chemistry | Animals | Models, Biological | Adenosine Triphosphatases - chemistry | Bacterial Proteins - metabolism | Adenosine Triphosphatases - genetics | Chromosomes - chemistry | Chromosomal Proteins, Non-Histone - chemistry | Fungal Proteins - metabolism | Cell proliferation | Protein research | Research | Chromosomes | Proteins | Eukaryotes | Chromatin | Cells
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Shaping mitotic chromosomes: From classical concepts to molecular mechanisms
by Kschonsak, Marc and Haering, Christian H
BioEssays, ISSN 0265-9247, 07/2015, Volume 37, Issue 7, pp. 755 - 766
How eukaryotic genomes are packaged into compact cylindrical chromosomes in preparation for cell divisions has remained one of the major unsolved questions of... 
topoisomerase II | cohesin | condensin | chromosome segregation | SMC complex | mitosis | chromosome condensation | Chromosome condensation | Mitosis | Cohesin | Chromosome segregation | Condensin | Topoisomerase II | SISTER-CHROMATID COHESION | XENOPUS EGG EXTRACTS | AURORA-B KINASE | CONDENSIN-I | TOPOISOMERASE-II-ALPHA | BIOCHEMISTRY & MOLECULAR BIOLOGY | X-RAY-DIFFRACTION | HISTONE H3 PHOSPHORYLATION | NUCLEOSOME CORE PARTICLE | METAPHASE CHROMOSOMES | LINKER HISTONE | BIOLOGY | Chromosomes - ultrastructure | DNA-Binding Proteins - physiology | Animals | Humans | Chromatin Assembly and Disassembly | Nucleosomes - physiology | Adenosine Triphosphatases - physiology | Chromosomes - physiology | Multiprotein Complexes - physiology | Molecular genetics | Physiological aspects | Genetic research | Genetic aspects | Research | Chromosomes | Prospects & Overviews
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Real-time imaging of DNA loop extrusion by condensin
by Ganji, Mahipal and Shaltiel, Indra A and Bisht, Shveta and Kim, Eugene and Kalichava, Ana and Haering, Christian H and Dekker, Cees
Science, ISSN 0036-8075, 2018, Volume 360, Issue 6384, pp. 102 - 105
It has been hypothesized that SMC protein complexes such as condensin and cohesin spatially organize chromosomes by extruding DNA into large loops. We directly... 
ORGANIZATION | CHROMOSOME | COMPACTION | MECHANISM | SINGLE-MOLECULE | MULTIDISCIPLINARY SCIENCES | SMC COMPLEXES | Hydrolysis | DNA - chemistry | Multiprotein Complexes - chemistry | Time Factors | Adenosine Triphosphatases - chemistry | Single Molecule Imaging - methods | Adenosine Triphosphate - chemistry | Nucleic Acid Conformation | DNA-Binding Proteins - chemistry | Saccharomyces cerevisiae Proteins - chemistry | Cellular proteins | DNA | Imaging systems | Genetic research | Genetic aspects | Research | Methods | Yeast | Energy use | Base pairs | Genomes | Reels | Real time | Condensin | Anchors | Extrusion rate | Imaging | Extrusion | Cohesin | Chromosomes | ATP | Adenosine triphosphate | Deoxyribonucleic acid--DNA
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Condensin structures chromosomal DNA through topological links
by Cuylen, Sara and Metz, Jutta and Haering, Christian H
Nature Structural and Molecular Biology, ISSN 1545-9993, 08/2011, Volume 18, Issue 8, pp. 894 - 901
The multisubunit condensin complex is essential for the structural organization of eukaryotic chromosomes during their segregation by the mitotic spindle, but... 
TOPOISOMERASE-II | PROTEIN | BUDDING YEAST | BIOCHEMISTRY & MOLECULAR BIOLOGY | COHESIN | SEGREGATION | 13S CONDENSIN | CELL BIOLOGY | MITOSIS | IN-VITRO | BIOPHYSICS | NON-SMC SUBUNITS | SISTER-CHROMATID SEPARATION | DNA-Binding Proteins - physiology | Saccharomyces cerevisiae - genetics | Adenosine Triphosphatases - metabolism | DNA, Fungal - chemistry | DNA-Binding Proteins - chemistry | Protein Subunits - metabolism | Multiprotein Complexes - physiology | DNA-Binding Proteins - metabolism | Multiprotein Complexes - metabolism | Chromosomes, Fungal - chemistry | Multiprotein Complexes - chemistry | Chromosomes, Fungal - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Chromosome Segregation - physiology | Adenosine Triphosphatases - chemistry | Protein Subunits - chemistry | Saccharomyces cerevisiae Proteins - physiology | Protein Subunits - physiology | Adenosine Triphosphatases - physiology | Binding Sites | Saccharomyces cerevisiae Proteins - chemistry | Polymerase chain reaction | Usage | DNA | Physiological aspects | Research | Chromosomes | Adenosine triphosphatase | Cell division | Eukaryotes | Yeast | Molecular structure | Molecular biology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text The condensin complex is a mechanochemical motor that translocates along DNA
by Terakawa, Tsuyoshi and Bisht, Shveta and Eeftens, J.M and Dekker, C and Haering, Christian H and Greene, Eric C
Science, ISSN 0036-8075, 11/2017, Volume 358, Issue 6363, pp. 672 - 676
Condensin plays crucial roles in chromosome organization and compaction, but the mechanistic basis for its functions remains obscure. We used single-molecule... 
ORGANIZATION | MITOSIS | COMPACTION | MECHANISM | MULTIDISCIPLINARY SCIENCES | ARCHITECTURE | COHESIN | CHROMOSOMES | SMC FAMILY | BINDING | GENOME | Saccharomyces cerevisiae - genetics | Adenosine Triphosphatases - metabolism | Adenosine Triphosphate | Single Molecule Imaging | Protein Transport | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Multiprotein Complexes - metabolism | Chromosomes, Fungal - metabolism | DNA, Fungal - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Molecular Motor Proteins - metabolism | Nucleotide sequencing | Translocation (Genetics) | Observations | Methods | DNA sequencing | Translocation | Coils | Yeast | Base pairs | Motor activity | Genomes | Compaction | Saccharomyces | Condensin | Hydrolysis | Compacting | Saccharomyces cerevisiae | ATP | Adenosine triphosphate | Deoxyribonucleic acid--DNA
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights