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by Davies, Gail and Lam, M and Harris, Sarah and Trampush, J.W and Luciano, Michelle and Hill, W.D and Hagenaars, Saskia and Ritchie, S.J and Marioni, Riccardo and Fawns-Ritchie, C and Liewald, D.C.M and Okely, J.A and Ahola-Olli, A.V and Barnes, C.L.K and Bertram, Lars and Bis, Joshua and Burdick, K.E and Christoforou, Anea and Derosse, P and Djurovic, Srdjan and Espeseth, Thomas and Giakoumaki, S and Giddaluru, Sudheer and Gustavson, D.E and Hayward, Caroline and Hofer, Edith and Ikram, Arfan and Karlsson, Robert and Knowles, E and Lahti, Jari and Leber, Isabelle and Li, S and Mather, R and Melle, Ingrid and Morris, D and Oldmeadow, Christopher and Palviainen, T and Payton, Antony and Pazoki, Raha and Petrovic, Katja and Reynolds, C and Sargurupremraj, M and Scholz, Markus and Smith, Jennifer A and Smith, Albert and Terzikhan, Natalie and Thalamuthu, Anbupalam and Trompet, Stella and Lee, Sven and Ware, Erin B and Windham, B Gwen and Wright, M.J and Yang, J and Yu, J and Ames, David and Amin, Najaf and Amouyel, Philippe and Aneassen, Ole and Armstrong, Nicola J and Assareh, A.A and Attia, John and Attix, D and Avramopoulos, D and Bennett, David and Böhmer, Marcel and Boyle, P.A and Brodaty, Henry and Campbell, Harry and Cannon, T.D and Cirulli, E.T and Congdon, E and Conley, E.D and Corley, J and Cox, Simon R and Dale, Anders and Dehghan, Abbas and Dick, D and Dickinson, D and Hagen, Knut and Evangelou, Evangelos and Faul, Jessica D and Ford, Ian and Freimer, N.A and Gao, H and Giegling, Ina and Gillespie, N.A and Gordon, Scott D and Gottesman, Rebecca and Griswold, Michael and Gudnason, V and Harris, Tamara and Hartmann, Annette M and Hatzimanolis, A and Heiss, Gerardo and Holliday, Elizabeth and Joshi, Peter and Kähönen, Mika and Kardia, S.L.R and Karlsson, I and Kleineidam, L and ...
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2098 - 16
textabstractGeneral cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine... 
COMMON VARIANTS | METAANALYSIS | REACTION-TIME | PROCESSING SPEED | MULTIDISCIPLINARY SCIENCES | INTELLIGENCE DIFFERENCES | SCHIZOPHRENIA | DCDC2 | DISCOVERY | GENOME-WIDE ASSOCIATION | REVEALS | Multifactorial Inheritance - genetics | Genetic Predisposition to Disease | Humans | Middle Aged | Genetic Loci - genetics | Neurodegenerative Diseases - genetics | Neurodevelopmental Disorders - genetics | Reaction Time - genetics | Young Adult | Mental Disorders - genetics | Adolescent | Aged, 80 and over | Cognition - physiology | Polymorphism, Single Nucleotide - genetics | Adult | Aged | Hypertension | Brain | Cognitive ability | Genomes | Gene expression | Neurodevelopmental disorders | Loci | Consortia | Illnesses | Mathematical analysis | Reaction time | Heritability | Gene loci | Polygenic inheritance | brain cortex | Medical and Health Sciences | Medicin och hälsovetenskap | major clinical study | osteoarthritis | Article | heart infarction | Klinisk medicin | lung cancer | identification method | longevity | grip strength | angina pectoris | genetic correlation | human | major depression | Neurologi | cognition | data set | aged | brain | gene locus | Clinical Medicine | Neurology | genome | vision | genetic analysis | controlled study | response time | adolescent | nervous system disorder | adult | hypertension | gene expression
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1470 - 10
Journal Article
JAMA Psychiatry, ISSN 2168-622X, 2019, Volume 76, Issue 5, pp. 470 - 472
Journal Article
PLoS Genetics, ISSN 1553-7390, 02/2017, Volume 13, Issue 2, p. e1006594
Male pattern baldness can have substantial psychosocial effects, and it has been phenotypically linked to adverse health outcomes such as prostate cancer and... 
REGULATOR | ANDROGENETIC ALOPECIA | PROSTATE-CANCER | HAIR LOSS | MEN | GENETICS & HEREDITY | DYSPLASIA | RISK | DIFFERENTIATION | HERITABILITY | GENOME-WIDE ASSOCIATION | Alopecia | Baldness | Gene mutations | Analysis | Genetic aspects | Research | Risk factors | Medical research | Funding | Cardiovascular disease | Genomes | Metabolism | Epidemiology | Medicine | Studies | Councils | Aging | Genetics | Hair loss | Prostate cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 2018, Volume 13, Issue 6, p. e0198187
Neurodegenerative disorders are associated with impaired cognitive function and worse physical health outcomes. This study aims to test whether polygenic risk... 
E280A PRESENILIN-1 MUTATION | UK BIOBANK | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | FRONTOTEMPORAL DEMENTIA | AMYOTROPHIC-LATERAL-SCLEROSIS | DYSFUNCTION | CARRIERS | GENOME-WIDE ASSOCIATION | POLYGENIC RISK | IMPAIRMENT | Frontotemporal Dementia - genetics | Frontotemporal Dementia - physiopathology | Alzheimer Disease - physiopathology | Genome-Wide Association Study | Amyotrophic Lateral Sclerosis - physiopathology | Genetic Association Studies | Risk Assessment | Amyotrophic Lateral Sclerosis - genetics | Humans | Middle Aged | Amyotrophic Lateral Sclerosis - psychology | United Kingdom | Cognition | Frontotemporal Dementia - psychology | Mental Status and Dementia Tests | Multifactorial Inheritance | Forced Expiratory Volume | Adult | Physical Fitness | Aged | Alzheimer Disease - genetics | Peak Expiratory Flow Rate | Muscle Strength | Alzheimer Disease - psychology | Analysis | Outcome and process assessment (Health Care) | Nervous system | Degeneration | Genetic aspects | Research | Risk factors | Research parks | Memory | Genomics | Cognitive ability | Disorders | Schizophrenia | Risk | Epidemiology | Consortia | Dementia disorders | Aging | Genetics | Alzheimer's disease | Age | Neurodegenerative diseases | Motor neurone disease | Health | Health risks | Amyotrophic lateral sclerosis | Medicine | Neurology | Cognition & reasoning | Mutation | Frontotemporal dementia | Alzheimers disease | Cognitive tasks | Psychiatry | Dementia
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 363 - 12
Evidence suggests that lifestyle factors, e.g. physical activity, moderate the manifestation of genetic susceptibility to obesity. The present study uses UK... 
MORTALITY | WOMEN | OBESITY | METAANALYSIS | MANIFESTATION | MULTIDISCIPLINARY SCIENCES | RISK | ALCOHOL-CONSUMPTION | MENTAL-HEALTH | CORONARY-HEART-DISEASE | PERSONALITY-TRAITS | Neurosis | Body mass index | Obesity | Adipose tissue | Physical activity | Quality control | Alcohol | Lifestyles | Regression analysis | Health risk assessment | Hip
Journal Article
Nature Communications, ISSN 2041-1723, 12/2016, Volume 7, Issue 1, p. 13629
Quantifying the microstructural properties of the human brain's connections is necessary for understanding normal ageing and disease. Here we examine brain... 
LIFE-SPAN | INTEGRITY | TRACTOGRAPHY | NEURITE ORIENTATION DISPERSION | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | DIFFUSION MRI | NODDI | MODEL | MICROSTRUCTURE | AGE | Brain - diagnostic imaging | Humans | Middle Aged | Male | United Kingdom | Magnetic Resonance Imaging | White Matter - diagnostic imaging | Biological Specimen Banks | Sex Factors | Aging | Adult | Female | Aged
Journal Article
TWIN RESEARCH AND HUMAN GENETICS, ISSN 1832-4274, 06/2019, Volume 22, Issue 3, pp. 131 - 139
Journal Article
European Neuropsychopharmacology, ISSN 0924-977X, 10/2019, Volume 29, pp. S186 - S187
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 1 - 7
Causes of the association between cognitive ability and health remain unknown, but may reflect a shared genetic aetiology. This study examines the causal... 
INTELLIGENCE | MULTIDISCIPLINARY SCIENCES | MIDLIFE | EDUCATIONAL-ATTAINMENT | HEIGHT | ASSOCIATION | CHILDHOOD | CORONARY-ARTERY-DISEASE | BLOOD-PRESSURE | AGE | DECLINE | Diabetes mellitus | Coronary vessels | Coronary artery | Cognitive ability | Cardiovascular disease | Blood pressure | Diabetes | Heart diseases | Educational attainment
Journal Article