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Journal Article
Molecular Psychiatry, ISSN 1359-4184, 06/2015, Volume 20, Issue 6, pp. 703 - 717
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 04/2018, Volume 23, Issue 4, pp. 1051 - 1065
Rett syndrome (RTT) is an X-linked, neurodevelopmental disorder caused primarily by mutations in the methyl-CpG-binding protein 2 (MECP2) gene, which encodes a... 
RETT-SYNDROME | PSYCHIATRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BRAIN-DEVELOPMENT | MECP2 MUTATIONS | NEUROSCIENCES | PLURIPOTENT STEM-CELLS | RESPIRATORY-FUNCTION | NEURAL DEVELOPMENT | POSTMITOTIC NEURONS | MOUSE MODEL | CORTEX DEVELOPMENT | NEUROLOGICAL SYMPTOMS | RNA, Small Interfering - genetics | Brain - embryology | Humans | Methyl-CpG-Binding Protein 2 - metabolism | Male | MicroRNAs - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Methyl-CpG-Binding Protein 2 - genetics | MAP Kinase Signaling System | Brain - metabolism | Neurogenesis - genetics | Cell Differentiation - genetics | Female | Neurons - metabolism | Induced Pluripotent Stem Cells - cytology | Proto-Oncogene Proteins c-akt - metabolism | Induced Pluripotent Stem Cells - metabolism | Cell Line | Signal Transduction | Rett Syndrome - metabolism | Animals | Neurogenesis - physiology | Rett Syndrome - pathology | Mice | MicroRNAs - genetics | Rett Syndrome - genetics | Cellular signal transduction | Genetic aspects | MicroRNA | Research | Neurogenesis | Brain | Cell culture | Animal models | Mental disorders | Disorders | AKT protein | Neurodevelopmental disorders | Kinases | Proteins | Methyl-CpG binding protein | Organoids | CpG islands | MiRNA | Extracellular signal-regulated kinase | MAP kinase | Ribonucleic acid--RNA | Embryos | Autism | Signaling | MeCP2 protein | Rett syndrome | Neural stem cells | Mutation | Differentiation | Three dimensional models | Cell migration | Pluripotency
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e71323
Psychiatric diseases, including schizophrenia, bipolar disorder and major depression, are projected to lead global disease burden within the next decade.... 
HIPPOCAMPUS | MESSENGER-RNA | ACETYLATION | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | STRAIN DIFFERENCES | VALPROIC ACID | MICE | HISTONE DEACETYLASE INHIBITORS | LITHIUM | NUCLEUS-ACCUMBENS | Transcription, Genetic - drug effects | Male | Neurons - cytology | Promoter Regions, Genetic - drug effects | Promoter Regions, Genetic - genetics | Brain - metabolism | Mi-2 Nucleosome Remodeling and Deacetylase Complex - antagonists & inhibitors | Time Factors | Behavior, Animal - drug effects | Histone Deacetylase 1 - antagonists & inhibitors | Benzamides - pharmacology | Neurons - drug effects | Chromatin - drug effects | Benzamides - chemistry | Affect - drug effects | Brain - cytology | Reproducibility of Results | Histone Deacetylase 2 - antagonists & inhibitors | Lithium - pharmacology | Mice, Inbred C57BL | Histone Deacetylase Inhibitors - chemistry | Brain - drug effects | Gene Expression Regulation - drug effects | Acetylation - drug effects | Animals | Histone Deacetylase Inhibitors - pharmacology | Mice | Histones - metabolism | Chromatin - genetics | Epigenetic inheritance | Brain | Chromatin | Antidepressants | Genes | Depression, Mental | Schizophrenia | Gene expression | Drugs | Drug abuse | Histone deacetylase | Immunoprecipitation | Transcription | Mental disorders | Medical services | Disorders | Lithium | Bipolar disorder | Genomes | Mental depression | Compounds | Kinases | Benzamide | Psychotropic drugs | Plasticity (behavioral) | Rodents | Inhibition | Acetylation | HDAC2 protein | Locomotor activity | Binding | Cortex (prefrontal) | Hydroxamic acid | Pharmacology | Nucleus accumbens | Amphetamine | Mood | Inhibitors | Acids | In vivo methods and tests
Journal Article
Chemical science, ISSN 2041-6520, 01/2015, Volume 6, Issue 1, pp. 804 - 815
Aiming towards the development of novel nootropic therapeutics to address the cognitive impairment common to a range of brain disorders, we set out to develop... 
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 03/2017, Volume 22, Issue 3, pp. 417 - 429
Journal Article
Chemical Science, ISSN 2041-6520, 01/2015, Volume 6, Issue 1, pp. 804 - 815
Aiming towards the development of novel nootropic therapeutics to address the cognitive impairment common to a range of brain disorders, we set out to develop... 
MEMORY | ACETYLATION | MOUSE MODEL | NEURODEGENERATION | P25/CDK5 | DEFICITS | SYNAPTIC PLASTICITY | EXTINCTION | EXPRESSION | CHEMISTRY, MULTIDISCIPLINARY | BRAIN | Binding | Enzymes | Inhibitors | Disorders | Histones | Mice | Cognition | Inhibition
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 05/2015, Volume 20, Issue 5, p. 573
Bipolar disorder (BD) is a heritable neuropsychiatric disorder with largely unknown pathogenesis. Given their prominent role in brain function and disease, we... 
Neuroplasticity | Care and treatment | Usage | MicroRNA | Analysis | Bipolar disorder | Gene expression | Health aspects | Risk factors
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 08/2013, Volume 18, Issue 8, pp. 922 - 929
Journal Article