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1. Full Text Extreme influenza epidemics and out-of-hospital cardiac arrest
by Onozuka, Daisuke and Hagihara, Akihito
International Journal of Cardiology, ISSN 0167-5273, 07/2018, Volume 263, pp. 158 - 162
There is compelling evidence for an association between influenza epidemics and major adverse cardiovascular events. However, the role of extreme influenza... 
Statistical analysis | Epidemiology | Influenza | Sudden death | Cardiac arrest | Japan - epidemiology | Out-of-Hospital Cardiac Arrest - epidemiology | Humans | Middle Aged | Risk Factors | Influenza, Human - epidemiology | Male | Out-of-Hospital Cardiac Arrest - diagnosis | Epidemics - prevention & control | Female | Influenza, Human - diagnosis | Registries | Aged | Epidemics | Analysis | Index Medicus
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2. Full Text Prehospital Epinephrine Use and Survival Among Patients With Out-of-Hospital Cardiac Arrest
by Hagihara, Akihito and Hasegawa, Manabu and Abe, Takeru and Nagata, Takashi and Wakata, Yoshifumi and Miyazaki, Shogo
JAMA, ISSN 0098-7484, 03/2012, Volume 307, Issue 11, pp. 1161 - 1168
CONTEXT Epinephrine is widely used in cardiopulmonary resuscitation for out-of-hospital cardiac arrest (OHCA). However, the effectiveness of epinephrine use... 
RECOMMENDED GUIDELINES | MEDICINE, GENERAL & INTERNAL | LIFE-SUPPORT | EUROPEAN-RESUSCITATION-COUNCIL | TASK-FORCE | UTSTEIN-STYLE | HEALTH-CARE-PROFESSIONALS | CHEST-COMPRESSION | STROKE-FOUNDATION | AMERICAN-HEART-ASSOCIATION | CARDIOPULMONARY-RESUSCITATION | Japan - epidemiology | Prospective Studies | Humans | Middle Aged | Male | Out-of-Hospital Cardiac Arrest - mortality | Out-of-Hospital Cardiac Arrest - drug therapy | Cardiopulmonary Resuscitation | Epinephrine - adverse effects | Epinephrine - therapeutic use | Registries - statistics & numerical data | Survival Analysis | Aged, 80 and over | Female | Aged | Adrenergic beta-Agonists - therapeutic use | Infusions, Intravenous | Emergency Medical Services | Adrenergic beta-Agonists - adverse effects | Blood Circulation | Epinephrine | Drugs | Dose-response relationship (Biochemistry) | Cardiac arrest | Dosage and administration | Product/Service Evaluations | Drug therapy | Prescription drugs | Heart attacks | Cardiopulmonary resuscitation--CPR | Mortality | Index Medicus | Abridged Index Medicus
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3. Full Text Out-of-Hospital Cardiac Arrests During the Japanese Professional Baseball Championship Series
by Onozuka, Daisuke and Hagihara, Akihito
The American Journal of Cardiology, ISSN 0002-9149, 06/2018, Volume 121, Issue 12, pp. 1471 - 1476
Because the Japan Professional Baseball Championship Series (Japan Series) is a stressful sports event, it is possible that watching Japan Series matches may... 
WORLD-CUP | CARDIAC & CARDIOVASCULAR SYSTEMS | ENDOTHELIAL DYSFUNCTION | ACUTE MYOCARDIAL-INFARCTION | CARDIOVASCULAR MORTALITY | HORMONE CRH | RISK | EUROPEAN FOOTBALL CHAMPIONSHIP | TYPE-2 DIABETES-MELLITUS | VENTRICULAR ARRHYTHMIA | POTENTIAL LINK | Japan - epidemiology | Out-of-Hospital Cardiac Arrest - epidemiology | Humans | Middle Aged | Male | Stress, Psychological - psychology | Out-of-Hospital Cardiac Arrest - psychology | Incidence | Young Adult | Regression Analysis | Adolescent | Sex Distribution | Adult | Female | Registries | Aged | Baseball - psychology | Heart | Elderly people | Sensitivity analysis | Statistical analysis | Health risks | Risk | Regression analysis | Confidence intervals | Regression models | Baseball | Surveillance | Influenza | Humidity | Poisson density functions | Behavior | Trends | Professional baseball | Cardiovascular diseases | Heart diseases | Elderly | Age | Geriatrics | Index Medicus | Abridged Index Medicus
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4. Full Text Out-of-hospital cardiac arrest risk attributable to temperature in Japan
by Onozuka, Daisuke and Hagihara, Akihito
Scientific Reports, ISSN 2045-2322, 01/2017, Volume 7, Issue 1, pp. 39538 - 39538
Several studies have estimated the associations between extreme temperatures and mortality and morbidity; however, few have investigated the attributable... 
VITAMIN-D | POPULATION | PUBLIC-ACCESS DEFIBRILLATION | CASE-CROSSOVER | MYOCARDIAL-INFARCTION | CAUSE-SPECIFIC MORTALITY | MULTIDISCIPLINARY SCIENCES | AMBIENT-TEMPERATURE | EXTREME TEMPERATURES | DEATH | HEAT WAVES | Heart | Temperature | Temperature effects | Cardiopulmonary resuscitation--CPR | Heart diseases | Morbidity | Index Medicus
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5. Full Text A comparison of medical litigation filed against obstetrics and gynecology, internal medicine, and surgery departments Ethics in Public Health, medical law, and health policy
by Hamasaki, Tomoko and Hagihara, Akihito
BMC Medical Ethics, 10/2015, Volume 16, Issue 1
Departments | Medical litigation | Obstetrics and gynecology | Duty to explain
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6. Full Text Within-summer variation in out-of-hospital cardiac arrest due to extremely long sunshine duration
by Onozuka, Daisuke|Hagihara, Akihito
International Journal of Cardiology, ISSN 0167-5273, 2016, Volume 231, pp. 120 - 124
Abstract Background Although several studies have reported the impacts of extremely high temperatures on cardiovascular diseases, no studies have examined... 
Cardiovascular | Environmental medicine | Sunshine | Statistical analysis | Epidemiology | Sudden death | Cardiac arrest | UNITED-STATES | VITAMIN-D | CARDIAC & CARDIOVASCULAR SYSTEMS | MORTALITY RISK | AMBIENT-TEMPERATURE | SEASONAL-VARIATION | Epidemiology Cardiac arrest | DEATH | SOUTHERN SWEDEN COHORT | SUN EXPOSURE | CARDIOVASCULAR-DISEASE | HEAT WAVES | Morbidity - trends | Japan - epidemiology | Risk Assessment - methods | Out-of-Hospital Cardiac Arrest - epidemiology | Follow-Up Studies | Humans | Middle Aged | Out-of-Hospital Cardiac Arrest - etiology | Young Adult | Sunlight - adverse effects | Time Factors | Adolescent | Aged, 80 and over | Adult | Aged | Retrospective Studies | Seasons | Weather | Medicine, Experimental | Medical research | Analysis | Index Medicus
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7. Full Text Age × Gender Interaction Effect on Resuscitation Outcomes in Patients With Out-of-Hospital Cardiac Arrest
by Hagihara, Akihito and Onozuka, Daisuke and Ono, Junko and Nagata, Takashi and Hasegawa, Manabu
The American Journal of Cardiology, ISSN 0002-9149, 08/2017, Volume 120, Issue 3, pp. 387 - 392
Although an interaction between gender and age has been shown to influence resuscitation outcomes in patients with out-of-hospital cardiac arrest (OHCA), this... 
Japan - epidemiology | Cardiopulmonary Resuscitation - methods | Out-of-Hospital Cardiac Arrest - epidemiology | Age Distribution | Prospective Studies | Survival Rate - trends | Age Factors | Humans | Middle Aged | Male | Emergency Medical Services - statistics & numerical data | Incidence | Young Adult | Out-of-Hospital Cardiac Arrest - therapy | Adolescent | Sex Factors | Sex Distribution | Adult | Female | Registries | Aged | Heart | Automation | Statistical analysis | Populations | Mortality | Risk | Emergency medical care | Gender | Drug overdose | Survival | Patients | Cardiopulmonary resuscitation--CPR | Confidence intervals | Studies | Mens health | Testosterone | Hospitals | Heart diseases | Significance | Circulation | Age | Resuscitation | Index Medicus | Abridged Index Medicus
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8. Full Text Impact of the consumption tax rate increase on out-of-hospital cardiac arrest in Japan: an interrupted time series analysis
by Onozuka, Daisuke and Nishimura, Kunihiro and Hagihara, Akihito
BMJ Open, ISSN 2044-6055, 06/2019, Volume 9, Issue 6, pp. e026361 - e026361
ObjectivesThe Japanese government increased the consumption tax rate from 5% to 8% on 1 April 2014. The impact of this policy on the incidence of... 
Studies | Cardiovascular disease | Mortality | Tax rates
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9. Full Text Internet suicide searches and the incidence of suicide in young people in Japan
by Hagihara, Akihito and Miyazaki, Shogo and Abe, Takeru
European Archives of Psychiatry and Clinical Neuroscience, ISSN 0940-1334, 2/2012, Volume 262, Issue 1, pp. 39 - 46
Although several case reports have suggested a relationship between accessing Internet suicide sites and the incidence of suicide, the influence of the... 
Neurology | Neurosciences | Medicine & Public Health | Adolescent | Internet | Suicide | Psychiatry | CYBERSUICIDE | PSYCHIATRY | CLINICAL NEUROLOGY | Japan - epidemiology | Age Factors | Humans | Internet - statistics & numerical data | Male | Suicide - statistics & numerical data | Incidence | Suicide - trends | Young Adult | Suicide - psychology | Adult | Female | Retrospective Studies | Seasons | Hydrogen sulfide | Medical colleges | Analysis | Online searching | Youth | Internet/Web search services | Teenagers | Acupuncture | Database searching | Index Medicus
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10. Full Text Spatiotemporal variations of extreme low temperature for emergency transport: a nationwide observational study
by Onozuka, Daisuke and Hagihara, Akihito
International Journal of Biometeorology, ISSN 0020-7128, 06/2017, Volume 61, Issue 6, pp. 1081 - 1094
Although recent studies have investigated the effect of extreme heat on emergency transport, few have investigated the spatiotemporal variations of extreme low... 
Distributed lag non-linear model | Multivariate meta-analysis | Extreme low temperature | Emergency transport | MORTALITY | PHYSIOLOGY | WEATHER | CORONARY EVENTS | AMBIENT-TEMPERATURE | COLD TEMPERATURES | AMBULANCE CALLS | TEMPORAL VARIATION | ALL-CAUSE | HEAT | ENVIRONMENTAL SCIENCES | BIOPHYSICS | ROOM VISITS | METEOROLOGY & ATMOSPHERIC SCIENCES | Japan - epidemiology | Multivariate Analysis | Regression Analysis | Respiratory Tract Diseases - epidemiology | Humans | Cardiovascular Diseases - epidemiology | Risk | Emergency Medical Dispatch - statistics & numerical data | Nonlinear Dynamics | Cold Temperature - adverse effects | Morbidity | Respiratory tract diseases | Extreme weather | Analysis | Climatology | Temperature | Spatial discrimination | Extreme high temperatures | Environmental factors | Regression analysis | Studies | Heterogeneity | Temperature effects | Respiratory diseases | Ambulance services | Spatial heterogeneity | Emergency vehicles | Temporal variations | Transport | Cardiovascular diseases | Heart diseases | Extreme low temperatures | Low temperatures | Index Medicus
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11. Full Text Nationwide variation in the effects of temperature on infectious gastroenteritis incidence in Japan
by Onozuka, Daisuke and Hagihara, Akihito
Scientific Reports, ISSN 2045-2322, 08/2015, Volume 5, Issue 1, pp. 12932 - 12932
Although several studies have investigated the effects of temperature on the incidence of infectious gastrointestinal disease in a single city or region, few... 
UNITED-STATES | MORTALITY | DIARRHEAL DISEASE | TIME-SERIES ANALYSIS | WEATHER VARIABILITY | MULTIDISCIPLINARY SCIENCES | NORWALK-LIKE VIRUSES | AMBIENT-TEMPERATURE | MOLECULAR EPIDEMIOLOGY | CLIMATE VARIABILITY | HEAT WAVES | Gastroenteritis - epidemiology | Japan - epidemiology | Multivariate Analysis | Temperature | Communicable Diseases - epidemiology | Humans | Risk | Nonlinear Dynamics | Incidence | Weather | Temperature effects | Gastroenteritis | Public health | Morbidity | Index Medicus
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12. Full Text Migraine-preventive prescription patterns by physician specialty in ambulatory care settings in the United States
by Takaki, Hiroko|Onozuka, Daisuke|Hagihara, Akihito
Preventive Medicine Reports, ISSN 2211-3355, 2018, Volume 9, pp. 62 - 67
Abstract Many adults with migraine who require preventive therapy are often not prescribed the proper medications. The most likely reason is that primary care... 
Internal Medicine | Primary care physician | Preventive medication | Migraine | The National Ambulatory Medical Care Survey
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13. Full Text Correction: Nabeshima, Y., et al. Analysis of Japanese Articles about Suicides Involving Charcoal Burning or Hydrogen Sulfide Gas. Int. J. Environ. Res. Public Health 2016, 13, 1013
by Nabeshima, Yoshihiro and Onozuka, Daisuke and Kitazono, Takanari and Hagihara, Akihito
International journal of environmental research and public health, ISSN 1660-4601, 12/2017, Volume 14, Issue 12, p. 1479
We wish to make the following three corrections to the published paper [...]. 
Hydrogen sulfide | Incineration | Mental health | Suicides & suicide attempts | Public health | Burning | Charcoal | n/a
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14. Acral lentiginous melanoma versus other melanoma: A single-center analysis in Japan
by Wada, Maiko and Ito, Takamichi and Tsuji, Gaku and Nakahara, Takeshi and Hagihara, Akihito and Furue, Masutaka and Uchi, Hiroshi
Journal of Dermatology, ISSN 0385-2407, 08/2017, Volume 44, Issue 8, pp. 932 - 938
We summarize herein our 14-year experience of conventional treatment outcomes before the era of molecular-targeted therapy and immunotherapy. Specifically, we... 
sentinel lymph node | acral lentiginous melanoma | prognostic factor | prognosis | outcome | SURVIVAL | DABRAFENIB | TRAMETINIB | BRAF | CANCER | DERMATOLOGY | METASTATIC MELANOMA | MEK INHIBITION | MUTATION | NIVOLUMAB | VEMURAFENIB | Japan - epidemiology | Immunotherapy - methods | Prognosis | Follow-Up Studies | Dacarbazine - therapeutic use | Humans | Middle Aged | Child, Preschool | Male | Antineoplastic Agents - therapeutic use | Dermatologic Surgical Procedures | Young Adult | Aged, 80 and over | Adult | Female | Retrospective Studies | Chemotherapy, Adjuvant | Child | Skin - pathology | Kaplan-Meier Estimate | Treatment Outcome | Lymphatic Metastasis | Melanoma - pathology | Disease-Free Survival | Adolescent | Aged | Sentinel Lymph Node Biopsy | Melanoma - therapy | Melanoma - mortality | Dacarbazine | Chemotherapy | Biopsy | Medical prognosis | Immunotherapy | Melanoma | Survival | Lymph nodes | Metastases
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15. Full Text The association of extreme temperatures and the incidence of tuberculosis in Japan
by Onozuka, Daisuke and Hagihara, Akihito
International Journal of Biometeorology, ISSN 0020-7128, 8/2015, Volume 59, Issue 8, pp. 1107 - 1114
Seasonal variation in the incidence of tuberculosis (TB) has been widely assumed. However, few studies have investigated the association between extreme... 
Environment, general | Animal Physiology | Climate change | Extreme temperatures | Environmental Health | Tuberculosis | Seasonality | Environment | Biophysics and Biological Physics | Plant Physiology | Meteorology | MYCOBACTERIUM-TUBERCULOSIS | UNITED-STATES | MORTALITY | PHYSIOLOGY | VITAMIN-D DEFICIENCY | ENVIRONMENTAL SCIENCES | BIOPHYSICS | MODELS | REACTIVATION | PULMONARY TUBERCULOSIS | INFECTION | METEOROLOGY & ATMOSPHERIC SCIENCES | INCUBATION PERIOD | Tuberculosis - epidemiology | Japan - epidemiology | Temperature | Humans | Middle Aged | Child, Preschool | Infant | Male | Incidence | Young Adult | Adolescent | Adult | Female | Aged | Nonlinear Dynamics | Child | Infant, Newborn | Greenhouse effect | Global temperature changes | Analysis | Biometeorology | Epidemiology | Index Medicus
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16. Full Text Chronic spontaneous urticaria: Implications of subcutaneous inflammatory cell infiltration in an intractable clinical course
by Itoh, Eriko, MD|Nakahara, Takeshi, MD, PhD|Murata, Maho, MD|Ito, Takamichi, MD|Onozuka, Daisuke, PhD|Furumura, Minao, MD, PhD|Hagihara, Akihito, DMSc, MPH|Furue, Masutaka, MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 1, pp. 363 - 366.e3
  [...]subcutaneous inflammatory cell infiltration is an integral part of the histopathological features of CSU and is potentially predictive of the failure of... 
Allergy and Immunology | ALLERGY | AUTOIMMUNITY | IMMUNOLOGY | Urticaria | Skin | Variables | Edema | Comorbidity | Biopsy | Rheumatoid arthritis | Neutrophils | Regression analysis | Autoimmune diseases | Multivariate analysis | Drug dosages | Age | Logistics | Index Medicus | Abridged Index Medicus
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17. Full Text Effects of advanced life support on patients who suffered cardiac arrest outside of hospital and were defibrillated
by Hagihara, Akihito and Onozuka, Daisuke and Nagata, Takashi and Hasegawa, Manabu
American Journal of Emergency Medicine, ISSN 0735-6757, 01/2018, Volume 36, Issue 1, pp. 73 - 78
The effects and relative benefits of advanced airway management and epinephrine on patients with out-of-hospital cardiac arrest (OHCA) who were defibrillated... 
Epinephrine | Heart arrest | Statistical analysis | Advanced airway management | Death | Sudden | Epidemiology | AUSTRALIAN-RESUSCITATION-COUNCIL | METAANALYSIS | PROPENSITY SCORE | STROKE-FOUNDATION | AMERICAN-HEART-ASSOCIATION | ENDOTRACHEAL INTUBATION | CARDIOPULMONARY-RESUSCITATION | EMERGENCY MEDICAL-SERVICES | TASK-FORCE | EMERGENCY MEDICINE | Japan - epidemiology | Prospective Studies | Humans | Middle Aged | Logistic Models | Male | Out-of-Hospital Cardiac Arrest - mortality | Survival Rate | Treatment Outcome | Advanced Cardiac Life Support - methods | Emergency Medical Services - statistics & numerical data | Out-of-Hospital Cardiac Arrest - therapy | Epinephrine - therapeutic use | Time Factors | Aged, 80 and over | Female | Registries | Aged | Airway Management - methods | Electric Countershock - methods | Heart | Emergency medical care | Cardiopulmonary resuscitation--CPR | Respiratory tract | Confidence intervals | Variables | Habitability | Airway management | Heart diseases | Drug dosages | Task forces | Automation | Adjustment | Feasibility studies | Fire stations | Management | Regression analysis | Patients | Survival | Hospitals | Councils | Neurological complications | Intubation | Index Medicus
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