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Journal of the Indian Institute of Science, ISSN 0019-4964, 07/2018, Volume 98, Issue 3, pp. 325 - 339
Quadruplexes are four-stranded DNA or RNA structures formed from tandem repeats of guanine-rich sequences. They are present throughout the genome, namely at... 
Materials Science | Engineering, general | Physics, general | Chemistry/Food Science, general | Materials Science, general | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology
Journal Article
Nature (London), ISSN 1476-4687, 05/2017, Volume 546, Issue 7656, pp. 107 - 112
... B. van Klinken [9]; Edward X. Guo [4]; Christoph Buettner [1]; Shozeb Haider [10]; Zhuan Bian [2]; Li Sun [1]; Clifford J. Rosen [3]; Mone Zaidi (corresponding... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Obesity - drug therapy | Receptors, FSH - genetics | Adipose Tissue, White - metabolism | Diet, High-Fat - adverse effects | Follicle Stimulating Hormone, beta Subunit - antagonists & inhibitors | Male | Osteoporosis - drug therapy | Adipocytes - drug effects | Uncoupling Protein 1 - biosynthesis | Adipose Tissue - metabolism | Antibodies - immunology | Female | Receptors, FSH - metabolism | Adiposity - drug effects | Ovariectomy | Mitochondria - metabolism | Mitochondria - drug effects | Receptors, FSH - antagonists & inhibitors | Haploinsufficiency | Antibodies - pharmacology | Animals | Oxygen Consumption - drug effects | Adipocytes - metabolism | Obesity - prevention & control | Follicle Stimulating Hormone, beta Subunit - immunology | Adipose Tissue, Beige - drug effects | Mice | Thermogenesis - drug effects | Adipose Tissue - drug effects | Adipose Tissue, Beige - metabolism | Adipose Tissue, White - drug effects | Adipose tissues | Physiological aspects | Physiological research | Follicle-stimulating hormone | Thermogenesis | Research | Binding | Obesity | Immunoglobulins | Adipose tissue | Pituitary hormones | Body fat | Menopause | Blocking | Adipocytes | Hormones | Metabolism | Density | Osteoporosis | Mitochondria | Biomedical materials | Bone mass | Pituitary | Biocompatibility | Bone loss | Adipose tissue (brown) | Index Medicus
Journal Article
Biochemical Society transactions, ISSN 0300-5127, 2009, Volume 37, Issue 3, pp. 583 - 588
Journal Article
Nucleic acids research, ISSN 1362-4962, 08/2007, Volume 35, Issue 17, pp. 5799 - 5808
... of a G-quadruplex in the human c-kit promoter Alan K. Todd, Shozeb M. Haider, Gary N. Parkinson and Stephen Neidle* Cancer Research UK Biomolecular Structure Group... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Promoter Regions, Genetic | DNA - chemistry | Base Sequence | Computer Simulation | Genomics | Humans | Computational Biology | Models, Molecular | G-Quadruplexes | Proto-Oncogene Proteins c-kit - genetics | Circular Dichroism | Index Medicus | Structural Biology
Journal Article
Nucleic acids research, ISSN 1362-4962, 02/2013, Volume 41, Issue 4, pp. 2723 - 2735
The human telomeric DNA sequence with four repeats can fold into a parallel-stranded propeller-type topology. NMR structures solved under molecular crowding... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Telomere - chemistry | DNA - chemistry | Humans | Water - chemistry | G-Quadruplexes | Molecular Dynamics Simulation | Cluster Analysis | Potassium - chemistry | Index Medicus | Structural Biology
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 11/2018, Volume 140, Issue 45, pp. 15366 - 15374
Cells have evolved inherent mechanisms, like homologous recombination (HR), to repair damaged DNA. However, repairs at telomeres can lead to genomic... 
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Models, Molecular | Telomere - chemistry | DNA - chemistry | Nucleic Acid Conformation | Humans | Crystallization | Index Medicus
Journal Article
International journal of biological macromolecules, ISSN 0141-8130, 07/2018, Volume 114, pp. 479 - 490
The interactions of c-myc G-quadruplex with three carbazole derivatives were investigated by UV–Vis spectrophotometry, fluorescence, CD spectroscopy, and... 
Spectroscopy | Pu22 | Carbazole derivatives | Molecular modeling | c-myc G-quadruplex | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Polymer Science | Science & Technology | Fluorescence | Nucleotide sequencing | Triazoles | Analysis | DNA sequencing | Index Medicus
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 01/2016, Volume 1364, Issue 1, pp. 5 - 10
Congenital adrenal hyperplasia (CAH) owing to 21‐hydroxylase deficiency is caused by the autosomal recessive in‐heritance of mutations in the gene CYP21A2.... 
phenotype | Khattab, A., T. Yuen, S. Al‐Malki, M. Yau, D. Kazmi, L. Sun, M. Harbison, S. Haider, M. Zaidi & M.I. New. 2015. A rare CYP21A2 mutation in a congenital adrenal hyperplasia kindred displaying genotype–phenotype nonconcordance. In “MARROW,” ed. by M. Zaidi. Ann. N.Y. Acad. Sci. 1364: 5–10 | CYP21A2 | p.R366H | congenital adrenal hyperplasia | genotype | Genotype | Phenotype | Congenital adrenal hyperplasia | Khattab, A., T. Yuen, S. Al-Malki, M. Yau, D. Kazmi, L. Sun, M. Harbison, S. Haider, M. Zaidi & M.I. New. 2015. A rare CYP21A2 mutation in a congenital adrenal hyperplasia kindred displaying | P.R366H | Glucocorticoids - therapeutic use | Adrenal Hyperplasia, Congenital - drug therapy | Exons | Expert Systems | Humans | Steroid 21-Hydroxylase - metabolism | Male | Adrenal Hyperplasia, Congenital - genetics | DNA Mutational Analysis | Gene Deletion | Steroid 21-Hydroxylase - genetics | Steroid 21-Hydroxylase - chemistry | Adrenal Glands - drug effects | Drug Therapy, Combination | Aromatase Inhibitors - therapeutic use | Child | Siblings | Adrenal Hyperplasia, Congenital - metabolism | Computational Biology | Models, Molecular | Treatment Outcome | Point Mutation | Adrenal Glands - metabolism | Pedigree | Adrenal Glands - physiopathology | Adrenal Hyperplasia, Congenital - physiopathology | Heterozygote | Protein Conformation | Amino Acid Substitution | Genetic research | Genetic aspects | Genetic disorders | Adrenogenital syndrome | Cytochrome P-450 | Adrenal glands | Genotype & phenotype | Mutation | Index Medicus | Mutations | Genes | Impairment | Disorders | Deletion | Genetics | Mathematical models | Gene sequencing
Journal Article
Biochimica et biophysica acta. General subjects, ISSN 0304-4165, 05/2017, Volume 1861, Issue 5, pp. 1246 - 1263
Journal Article