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1. Full Text Synthesis of (R)-Boc-2-methylproline via a Memory of Chirality Cyclization. Application to the Synthesis of Veliparib, a Poly(ADP-ribose) Polymerase Inhibitor
by Kolaczkowski, L and Barkalow, J and Barnes, DM and Haight, A and Pritts, W and Schellinger, A
JOURNAL OF ORGANIC CHEMISTRY, ISSN 0022-3263, 04/2019, Volume 84, Issue 8, pp. 4837 - 4845
(R)-Boc-2-methylproline (3a) was synthesized in good yield with excellent stereochemical control from alanine benzyl ester hydrochloride 11. The process, which... 
ASYMMETRIC-SYNTHESIS | ABT-888 | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | N-ALKYLATION | DERIVATIVES | DISCOVERY
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2. Full Text Efficacy and safety of a monthly buprenorphine depot injection for opioid use disorder: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
by Haight, Barbara R and Learned, Susan M and Laffont, Celine M and Fudala, Paul J and Zhao, Yue and Garofalo, Amanda S and Greenwald, Mark K and Nadipelli, Vijay R and Ling, Walter and Heidbreder, Christian and Andersen, James L and Bailey, Genie L and Bartley, Scott Robert and Biunno, Michael J and Boyett, Brent and Carr, Jesse M and Cifuentes, Eduardo and Duarte-Sckell, Sandra Daniela and Dueno, Otto R and Harrison, Boyde J and Hassman, David R and Hoffman, Kent Steven and Isacesu, Valentin and Ishaque, Saleem and Kakar, Rishi and Kampman, Kyle and Knapp, Richard D and Konis, George and Kunovac, Jelena and Kwentus, Joseph A and Levinson, Lawrence S and Malhotra, Shishuka and Mehra, Vishaal and Mofsen, Ricky Stuart and Peyton, Marvin Lane and Pujari, Gita G and Ranjan, Rakesh and Rutrick, Daniel and Seal, Gregory and Segal, Scott Daniel and Shiwach, Rajinder and Thomas, Haydn Mikel and Ventre, Peter Paul and Vijapura, Amit K and Walling, David P and Wiest, Katharina L and RB-US-13-0001 Study Investigators
The Lancet, ISSN 0140-6736, 02/2019, Volume 393, Issue 10173, pp. 778 - 790
RBP-6000, referred to as BUP-XR (extended-release buprenorphine), is a subcutaneously injected, monthly buprenorphine treatment for opioid use disorder. BUP-XR... 
GLOBAL BURDEN | SUPPORT | MEDICINE, GENERAL & INTERNAL | SUSTAINED-RELEASE FORMULATION | CLINICAL-TRIAL | RBP-6000 | DISEASE | PREVENTION | ADDICTION | DEPENDENCE | Clinical trials | Drug abuse | Usage | Product development | Buprenorphine | Analysis | Headache | Substance abuse treatment | Mental disorders | Opioids | Counseling | Patient safety | Safety | Product safety | Constipation | Drug dosages | Urine | Dosing | Signs and symptoms | Effectiveness | Narcotics | Abuse | Nausea | Injection | Patients | Injections | Naloxone | Adults
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3. Full Text ENDF/B-VII.0: Next Generation Evaluated Nuclear Data Library for Nuclear Science and Technology
by Chadwick, M.B and Obložinský, P and Herman, M and Greene, N.M and McKnight, R.D and Smith, D.L and Young, P.G and MacFarlane, R.E and Hale, G.M and Frankle, S.C and Kahler, A.C and Kawano, T and Little, R.C and Madland, D.G and Moller, P and Mosteller, R.D and Page, P.R and Talou, P and Trellue, H and White, M.C and Wilson, W.B and Arcilla, R and Dunford, C.L and Mughabghab, S.F and Pritychenko, B and Rochman, D and Sonzogni, A.A and Lubitz, C.R and Trumbull, T.H and Weinman, J.P and Brown, D.A and Cullen, D.E and Heinrichs, D.P and McNabb, D.P and Derrien, H and Dunn, M.E and Larson, N.M and Leal, L.C and Carlson, A.D and Block, R.C and Briggs, J.B and Cheng, E.T and Huria, H.C and Zerkle, M.L and Kozier, K.S and Courcelle, A and Pronyaev, V and van der Marck, S.C
Nuclear Data Sheets, ISSN 0090-3752, 2006, Volume 107, Issue 12, pp. 2931 - 3060
We describe the next generation general purpose Evaluated Nuclear Data File, ENDF/B-VII.0, of recommended nuclear data for advanced nuclear science and... 
PRECOMPOUND DECAY MODEL | CONTINUUM ANGULAR-DISTRIBUTIONS | ENERGY-DEPENDENCE | DELAYED NEUTRON FRACTION | MULTISTEP-COMPOUND | PHYSICS, NUCLEAR | PHOTONEUTRON CROSS-SECTIONS | EMISSION PROBABILITIES | PHOTONUCLEAR PHYSICS | RADIATION TRANSPORT | STATISTICAL-MODEL | Nuclear nonproliferation | Libraries | Databases | Uranium | Nuclear physics
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4. Full Text Association of 3 Different Antihypertensive Medications With Hip and Pelvic Fracture Risk in Older Adults: Secondary Analysis of a Randomized Clinical Trial
by Puttnam, Rachel and Davis, Barry R and Pressel, Sara L and Whelton, Paul K and Cushman, William C and Louis, Gail T and Margolis, Karen L and Oparil, Suzanne and Williamson, Jeffrey and Ghosh, Alokananda and Einhorn, Paula T and Barzilay, Joshua I and Antihypertensive Lipid-Lowering Tr and Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) Collaborative Research Group and for the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) Collaborative Research Group
JAMA Internal Medicine, ISSN 2168-6106, 01/2017, Volume 177, Issue 1, pp. 67 - 76
IMPORTANCE: On the basis of observational studies, the use of thiazide diuretics for the treatment of hypertension is associated with reduced fracture risk... 
BLOCKERS | LIPID-LOWERING TREATMENT | MEDICINE, GENERAL & INTERNAL | BONE-MINERAL DENSITY | THIAZIDE DIURETICS | HEART-ATTACK TRIAL | ALLHAT | COHORT | HEALTH | BLOOD-PRESSURE | OSTEOPOROSIS | Chlorthalidone - therapeutic use | United States - epidemiology | Follow-Up Studies | Risk Assessment | Humans | Risk Factors | Male | Hip Fractures - epidemiology | Antihypertensive Agents - therapeutic use | Amlodipine - therapeutic use | Pelvic Bones - injuries | Lisinopril - therapeutic use | Hip Fractures - prevention & control | Intention to Treat Analysis | Female | Aged
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5. Full Text Evaluation of complex and dynamic safety tasks in human learning using the ACT-R and SOAR skill acquisition theories
by Oyewole, Samuel A and Farde, Amey M and Haight, Joel M and Okareh, Oladapo T
Computers in Human Behavior, ISSN 0747-5632, 2011, Volume 27, Issue 5, pp. 1984 - 1995
► Human-centered analytical approach to learning dynamic and complex tasks. ► This research compares the task times of the model as well as the subjects. ►... 
Declarative knowledge | Skill acquisition | SOAR | ACT-R | Procedural knowledge | Cognitive psychology | COGNITIVE SKILL | ATTENTION | COMPILATION | MODEL | PSYCHOLOGY, EXPERIMENTAL | PSYCHOLOGY, MULTIDISCIPLINARY | GENERAL INTELLIGENCE | ARCHITECTURE | SELECTION | Human | Learning | Dynamic tests | Tasks | Computer simulation | Dynamics | Circuit boards | Mathematical models
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6. Full Text Transplantation Outcomes for Severe Combined Immunodeficiency, 2000–2009
by Pai, Sung-Yun and Logan, Brent R and Griffith, Linda M and Buckley, Rebecca H and Parrott, Roberta E and Dvorak, Christopher C and Kapoor, Neena and Hanson, Imelda C and Filipovich, Alexandra H and Jyonouchi, Soma and Sullivan, Kathleen E and Small, Trudy N and Burroughs, Lauri and Skoda-Smith, Suzanne and Haight, Ann E and Grizzle, Audrey and Pulsipher, Michael A and Chan, Ka Wah and Fuleihan, Ramsay L and Haddad, Elie and Loechelt, Brett and Aquino, Victor M and Gillio, Alfred and Davis, Jeffrey and Knutsen, Alan and Smith, Angela R and Moore, Theodore B and Schroeder, Marlis L and Goldman, Frederick D and Connelly, James A and Porteus, Matthew H and Xiang, Qun and Shearer, William T and Fleisher, Thomas A and Kohn, Donald B and Puck, Jennifer M and Notarangelo, Luigi D and Cowan, Morton J and O'Reilly, Richard J
The New England Journal of Medicine, ISSN 0028-4793, 07/2014, Volume 371, Issue 5, pp. 434 - 446
An analysis of outcomes from 2000 through 2009 at 25 centers treating children with severe combined immunodeficiency (SCID) showed that early transplantation... 
MEDICINE, GENERAL & INTERNAL | DISEASES | BONE-MARROW-TRANSPLANTATION | SOYBEAN AGGLUTININ | EXPERIENCE | STEM-CELL TRANSPLANTATION | RECONSTITUTION | CHILDHOOD | LYMPHOCYTES | CHILDREN | Graft vs Host Disease - epidemiology | Humans | Severe Combined Immunodeficiency - mortality | Severe Combined Immunodeficiency - therapy | Infant | Male | Survival Rate | Treatment Outcome | Severe Combined Immunodeficiency - immunology | Hematopoietic Stem Cell Transplantation - mortality | Incidence | Retreatment | CD3 Complex - blood | Hematopoietic Stem Cell Transplantation - adverse effects | Immunoglobulin A - blood | Lymphocyte Count | Female | T-Lymphocytes - immunology | Retrospective Studies | Transplantation Conditioning | Siblings | Transplantation of organs, tissues, etc | Research | Health aspects | Patient outcomes | Reorganization and restructuring | Immunodeficiency | Cell proliferation | Cell survival | Severe combined immunodeficiency | Transplants & implants | Hypersensitivity | Infections | Infants | Lymphocytes T | Transplantation | CD3 antigen | Immunoglobulin A | Hemopoiesis | CD4 antigen | Infectious diseases | Donors | Stem cells | Bone marrow | Children | Immune system
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7. Measurement and resonance analysis of the Np-237 neutron capture cross section
by Guerrero, C and Cano-Ott, D and Mendoza, E and Abbondanno, U and Aerts, G and Alvarez-Velarde, F and Andriamonje, S and Andrzejewski, J and Assimakopoulos, P and Audouin, L and Badurek, G and Baumann, P and Becvar, F and Belloni, F and Berthoumieux, E and Calvino, F and Calviani, M and Capote, R and Carrapico, C and de Albornoz, AC and Cennini, P and Chepel, V and Chiaveri, E and Colonna, N and Cortes, G and Couture, A and Cox, J and Dahlfors, M and David, S and Dillmann, I and Dolfini, R and Domingo-Pardo, C and Dridi, W and Duran, I and Eleftheriadis, C and Embid-Segura, M and Ferrant, L and Ferrari, A and Ferreira-Marques, R and Fitzpatrick, L and Frais-Koelbl, H and Fujii, K and Furman, W and Goncalves, I and Gonzalez-Romero, E and Goverdovski, A and Gramegna, F and Griesmayer, E and Gunsing, F and Haas, B and Haight, R and Heil, M and Herrera-Martinez, A and Igashira, M and Isaev, S and Jericha, E and Kappeler, F and Kadi, Y and Karadimos, D and Karamanis, D and Ketlerov, V and Kerveno, M and Koehler, P and Konovalov, V and Kossionides, E and Krticka, M and Lampoudis, C and Leeb, H and Lindote, A and Lopes, I and Lossito, R and Lozano, M and Lukic, S and Marganiec, J and Marques, L and Marrone, S and Martinez, T and Massimi, C and Mastinu, P and Mengoni, A and Milazzo, PM and Moreau, C and Mosconi, M and Neves, F and Oberhummer, H and O'Brien, S and Oshima, M and Pancin, J and Papachristodoulou, C and Papadopoulos, C and Paradela, C and Patronis, N and Pavlik, A and Pavlopoulos, P and Perrot, L and Pigni, MT and Plag, R and Plompen, A and Plukis, A and Poch, A and ... and N TOF Collaboration
PHYSICAL REVIEW C, ISSN 2469-9985, 04/2012, Volume 85, Issue 4
The neutron capture cross section of Np-237 was measured between 0.7 and 500 eV at the CERN n_TOF facility using the 4 pi BaF2 Total Absorption Calorimeter.... 
PHYSICS, NUCLEAR | PARAMETERS | SIMULATION | FACILITY N-TOF
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8. Full Text Trajectory Analysis for Collisions Involving Bicycles and Automobiles
by Haight, W. R. “Rusty”, author
SAE technical paper series, Volume 900368.
Determining the impact velocity of a striking vehicle in a bicycle-involved collision is arguably the most difficult part of preparing an analysis or... 
Impact tests | Injuries | Crash research
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9. Full Text Outcomes of Measurable Residual Disease in Pediatric Acute Myeloid Leukemia before and after Hematopoietic Stem Cell Transplant: Validation of Difference from Normal Flow Cytometry with Chimerism Studies and Wilms Tumor 1 Gene Expression
by Jacobsohn, David A and Loken, Michael R and Fei, Mingwei and Adams, Alexia and Adams, Roberta H and Brodersen, Lisa Eidenschink and Logan, Brent R and Ahn, Kwang Woo and Shaw, Bronwen E and Kletzel, Morris and Olszewski, Marie and Khan, Sana and Meshinchi, Soheil and Keating, Amy and Harris, Andrew and Teira, Pierre and Duerst, Reggie E and Margossian, Steven P and Martin, Paul L and Petrovic, Aleksandra and Dvorak, Christopher C and Nemecek, Eneida R and Boyer, Michael W and Chen, Allen R and Davis, Jeffrey H and Shenoy, Shalini and Savasan, Sureyya and Hudspeth, Michelle P and Lewis, Victor A and Kheradpour, Albert and Kasow, Kimberly A and Gillio, Alfred P and Haight, Ann E and Bhatia, Monica and Bambach, Barbara J and Haines, Hilary L and Quigg, Troy C and Greiner, Robert J and Talano, Julie-An M and Delgado, David C and Cheerva, Alexandra and Gowda, Madhu and Ahuja, Sanjay and Ozkaynak, Mehmet and Mitchell, David and Schultz, Kirk R and Fry, Terry J and Loeb, David M and Pulsipher, Michael A
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 10/2018, Volume 24, Issue 10, pp. 2040 - 2046
We enrolled 150 patients in a prospective multicenter study of children with acute myeloid leukemia undergoing hematopoietic stem cell transplantation (HSCT)... 
Stem cell transplantation | Laboratory hematology | Measurable residual disease | Cytogenetics and molecular genetics | AML | TARGET | IMMUNOLOGY | CHILDREN | TRANSPLANTATION | THERAPY | WT1 | RELAPSE RISK | HEMATOLOGY | TOOL | Pediatrics | Analysis | Stem cells | Genetic research | Transplantation | Nephroblastoma | Gene expression | Hematopoietic stem cells | Tumors
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10. Full Text Cigarette smoking and gray matter brain volumes in middle age adults: the CARDIA Brain MRI sub-study
by Elbejjani, Martine and Auer, Reto and Jacobs, David R and Haight, Thaddeus and Davatzikos, Christos and Goff, David C and Bryan, R. Nick and Launer, Lenore J
Translational Psychiatry, ISSN 2158-3188, 12/2019, Volume 9, Issue 1, pp. 78 - 10
Cigarette smoking has been associated with dementia and dementia-related brain changes, notably gray matter (GM) volume atrophy. These associations are thought... 
YOUNG-ADULTS | INDIVIDUALS | DEPRESSION | CINGULATE | METAANALYSIS | RISK-FACTOR | ALCOHOL | PSYCHIATRY | DRUG-ADDICTION | NICOTINE EXPOSURE | PROGRESSION | Alcohol | Middle age | Smoking | Dementia
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11. Full Text Neutron physics of the Re/Os clock. III. Resonance analyses and stellar (n, gamma) cross sections of Os-186,Os-187,Os-188
by Fujii, K and Mosconi, M and Mengoni, A and Domingo-Pardo, C and Kappeler, F and Abbondanno, U and Aerts, G and Alvarez-Pol, H and Alvarez-Velarde, F and Andriamonje, S and Andrzejewski, J and Assimakopoulos, P and Audouin, L and Badurek, G and Baumann, P and Becvar, F and Belloni, F and Berthoumieux, E and Bisterzo, S and Calviani, M and Calvino, F and Cano-Ott, D and Capote, R and de Albornoz, AC and Cennini, P and Chepel, V and Chiaveri, E and Colonna, N and Cortes, G and Couture, A and Cox, J and Dahlfors, M and David, S and Dillmann, I and Dolfini, R and Dridi, W and Duran, I and Eleftheriadis, C and Embid-Segura, M and Ferrant, L and Ferrari, A and Ferreira-Marques, R and Fitzpatrick, L and Frais-Koelbl, H and Furman, W and Gallino, R and Goncalves, I and Gonzalez-Romero, E and Goverdovski, A and Gramegna, F and Griesmayer, E and Guerrero, C and Gunsing, F and Haas, B and Haight, R and Heil, M and Herrera-Martinez, A and Igashira, M and Isaev, S and Jericha, E and Kadi, Y and Karamanis, D and Karadimos, D and Kerveno, M and Ketlerov, V and Koehler, P and Konovalov, V and Kossionides, E and Krticka, M and Lamboudis, C and Leeb, H and Lindote, A and Lopes, I and Lozano, M and Lukic, S and Marganiec, J and Marques, L and Marrone, S and Massimi, C and Mastinu, P and Milazzo, PM and Moreau, C and Neves, F and Oberhummer, H and Oshima, M and O'Brien, S and Pancin, J and Papachristodoulou, C and Papadopoulos, C and Paradela, C and Patronis, N and Pavlik, A and Pavlopoulos, P and Perrot, L and Plag, R and Plompen, A and Plukis, A and Poch, A and Praena, J and Pretel, C and ...
PHYSICAL REVIEW C, ISSN 0556-2813, 07/2010, Volume 82, Issue 1
Neutron resonance analyses have been performed for the capture cross sections of Os-186, Os-187, and Os-188 measured at the n_TOF facility at CERN. Resonance... 
OSMIUM ISOTOPES | COSMOCHRONOLOGY | METAL-POOR | RE-187-OS-187 SYSTEMATICS | CHEMICAL EVOLUTION | PHYSICS, NUCLEAR | NUCLEOSYNTHESIS | CAPTURE | GIANT BRANCH STARS | STATISTICAL-MODEL | AGE
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12. Full Text Associations of plasma clusterin and Alzheimer's disease-related MRI markers in adults at mid-life: The CARDIA Brain MRI sub-study
by Haight, T and Bryan, RN and Meirelles, O and Tracy, R and Fornage, M and Richard, M and Nasrallah, I and Yaffe, K and Jacobs, DR and Lewis, C and Schreiner, P and Sidney, S and Davatzikos, C and Launer, LJ
PLOS ONE, ISSN 1932-6203, 01/2018, Volume 13, Issue 1, p. e0190478
Background Clinical and epidemiological studies of older persons have implicated clusterin in Alzheimer's disease (AD) pathogenesis. In the context of... 
IDENTIFIES VARIANTS | METABOLIC SYNDROME | NEUROFIBRILLARY CHANGES | GRAY-MATTER LOSS | ATROPHY | IMAGES | MULTIDISCIPLINARY SCIENCES | RISK | MILD COGNITIVE IMPAIRMENT | PROGRESSION | GENOME-WIDE ASSOCIATION | Brain | Advertising executives | Magnetic resonance imaging | Analysis | Epidemiology | Alzheimer's disease | Enzyme-linked immunosorbent assay
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