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Human Gene Therapy, ISSN 1043-0342, 05/2019, Volume 30, Issue 5, pp. 535 - 543
Clustered regularly interspaced short palindromic repeats (CRISPR) editing is being considered as a potential gene repair therapy to treat Duchenne muscular... 
Review | MEDICINE, RESEARCH & EXPERIMENTAL | CRISPR | GENE-REPLACEMENT | TOLERANCE | MUSCLE | dystrophin | editing | DELIVERY | THERAPY | INJECTION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | AAV | IMMUNE-RESPONSES | MOUSE MODEL | GENETICS & HEREDITY | DMD | MICE | dog | EXPRESSION | Therapy | Intravenous administration | Muscles | Editing | Viruses | Mammals | Muscular dystrophy | Restoration | Rodents | Duchenne's muscular dystrophy | Scaling | Dystrophy | Dystrophin
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2015, Volume 23, pp. S160 - S161
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 01/2012, Volume 112, Issue 2, pp. 332 - 332
Journal Article
Muscle & nerve, ISSN 0148-639X, 12/2012, Volume 46, Issue 6, pp. 948 - 950
Journal Article
Journal of Pathology, ISSN 0022-3417, 01/2011, Volume 223, Issue 1, pp. 88 - 98
The mechanism of force reduction is not completely understood in Duchenne muscular dystrophy (DMD), a dystrophin-deficient lethal disease. Nitric oxide... 
mdx | ryanodine receptor 1 | nitrosative stress | nitrotyrosination | Duchenne muscular dystrophy | nNOS | S-nitrosylation | dystrophin | δ-sarcoglycan | mdx4cv
Journal Article
PLoS Currents, ISSN 2157-3999, 2015, Volume 7
The mdx mouse is the most frequently used animal model for Duchenne muscular dystrophy (DMD), a fatal muscle disease caused by the loss of dystrophin. Mdx mice... 
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2011, Volume 709, pp. 75 - 89
The primary function of skeletal muscle is to generate force. Muscle force production is compromised in various forms of acquired and/or inherited muscle... 
Genetic Therapy | Animals | Muscle Contraction | Mice | Muscular Diseases - pathology | Muscle, Skeletal - physiology | Muscle Strength | Muscular Diseases - therapy | Muscle Fibers, Skeletal - physiology | Disease Models, Animal | Index Medicus | Tetanic force | Eccentric contraction | Twitch force | Grip strength | Treadmill | Gene therapy | Skeletal muscle
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2019, Volume 1937, pp. 281 - 294
Many diseases affect multiple tissues and/or organ systems, or affect tissues that are broadly distributed. For these diseases, an effective gene therapy will... 
Adult dogs | Neonatal mice | AAV | Adult mice | Neonatal dogs | DMD | Systemic delivery | Index Medicus
Journal Article
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, ISSN 1939-5116, 03/2018, Volume 10, Issue 2, p. e1514
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2015, Volume 23, pp. S159 - S160
Journal Article
American Journal of Physiology, ISSN 0363-6135, 09/2011, Volume 301, Issue 3, p. H773
To study ... signaling in the endothelium of murine feed arteries, we determined the in vitro stability of endothelial cell (EC) tubes freshly isolated from... 
Signal transduction | Calcium | Morphology | Rodents | Veins & arteries
Journal Article
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