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1.
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Pan-cancer analysis of intratumor heterogeneity as a prognostic determinant of survival
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 9, pp. 10051 - 10063
Heterogeneity | Evolution | Immune surveillance | Survival | Cancer | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Multivariate Analysis | Genetic Predisposition to Disease - genetics | Prognosis | Humans | Neoplasms - classification | Clone Cells - metabolism | Genetic Heterogeneity | Clone Cells - pathology | Neoplasms - genetics | Survival Analysis | Polymorphism, Single Nucleotide | Mutation | Neoplasms - pathology | Index Medicus
Journal Article
Journal of clinical oncology, ISSN 0732-183X, 12/2018, Volume 36, Issue 36, pp. 3591 - 3600
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Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer
Nature medicine, ISSN 1078-8956, 01/2013, Volume 19, Issue 1, pp. 50 - 56
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Kidney Neoplasms - genetics | Polycomb Repressive Complex 2 - genetics | Humans | Gene Expression Regulation, Neoplastic | Carcinoma, Renal Cell - genetics | Kidney Neoplasms - metabolism | Hypoxia-Inducible Factor 1 - metabolism | DNA Methylation | Neoplasm Metastasis | Base Sequence | Receptors, CXCR4 - genetics | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Carcinoma, Renal Cell - pathology | Transcription Factors - genetics | Mice, SCID | Sequence Analysis, DNA | Receptors, CXCR4 - metabolism | Transcription Factors - metabolism | Carcinoma, Renal Cell - metabolism | Animals | Carcinoma, Renal Cell - secondary | Cell Line, Tumor | Kidney Neoplasms - pathology | Mice, Inbred NOD | Mice | Histones - metabolism | Transcription factors | Kidney cancer | Development and progression | Tumor suppressor genes | Genetic aspects | Metastasis | Research | Health aspects | Cancer | Epigenetics | Signaling | Kidney diseases | Index Medicus
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Tumor mutational load predicts survival after immunotherapy across multiple cancer types
Nature genetics, ISSN 1061-4036, 02/2019, Volume 51, Issue 2, pp. 202 - 206
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Immunotherapy - methods | Neoplasms - therapy | Neoplasms - genetics | Antineoplastic Agents - immunology | Neoplasms - immunology | Humans | Tumor Burden - genetics | High-Throughput Nucleotide Sequencing - methods | Mutation - genetics | Tumor Burden - immunology | Usage | Research | Gene mutations | Immunotherapy | Oncology, Experimental | Cancer | Laboratories | Lung cancer | Melanoma | Histology | Metastasis | Gene expression | Cancer therapies | Patients | Survival | Metastases | Next-generation sequencing | Immune checkpoint | Biomarkers | Mutation | Tumors | Index Medicus
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Nature medicine, ISSN 1078-8956, 06/2017, Volume 23, Issue 6, pp. 703 - 713
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Prospective Studies | Genomics | Humans | Data Mining | Male | Sequence Analysis, DNA | Feasibility Studies | Neoplasm Metastasis - genetics | Neoplasms - genetics | Female | Biomarkers, Tumor - genetics | High-Throughput Nucleotide Sequencing | DNA, Neoplasm - genetics | Mutation | Neoplasms - pathology | Cohort Studies | Development and progression | Genetic aspects | Metastasis | Research | Gene mutations | Cancer | Index Medicus
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Cancer cell, ISSN 1535-6108, 12/2013, Volume 24, Issue 6, pp. 738 - 750
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | NF-E2-Related Factor 2 - physiology | Kidney Neoplasms - genetics | Sequestosome-1 Protein | Humans | Carcinoma, Renal Cell - genetics | Molecular Sequence Data | Gene Dosage | Chromosomes, Human, Pair 5 | Adaptor Proteins, Signal Transducing - physiology | NF-E2-Related Factor 2 - analysis | Animals | Base Sequence | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Mice | Medical colleges | Genes | Kidney cancer | Cancer | Index Medicus
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eLife, ISSN 2050-084X, 02/2016, Volume 5, Issue 2016
Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Mitochondrial DNA | Genetic aspects | Genetic variation | Health aspects | Cancer | Immune response | Kidneys | Copy number | Genomes | Gene expression | Estimates | Studies | Mitochondria | Urinary bladder | Mutation | Variation | Respiration | Deoxyribonucleic acid--DNA | Kidney transplantation | Tumors | Index Medicus
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The Journal of urology, ISSN 0022-5347, 2014, Volume 191, Issue 2, pp. 341 - 345
Urology | reoperation | carcinoma | neoplasm recurrence | BCG vaccine | urinary bladder | local | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Tumors of the urinary system | Urinary tract. Prostate gland | Infectious diseases | Bacterial diseases | Human bacterial diseases | Tuberculosis and atypical mycobacterial infections | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Multivariate Analysis | Reoperation | Neoplasm Recurrence, Local - prevention & control | Neoplasm Invasiveness | Humans | Middle Aged | Male | Urinary Bladder Neoplasms - drug therapy | Urinary Bladder Neoplasms - surgery | Disease Progression | Urinary Bladder Neoplasms - pathology | Female | Aged | Retrospective Studies | Administration, Intravesical | BCG Vaccine - therapeutic use | BCG Vaccine - administration & dosage | Care and treatment | Cancer patients | Relapse | Surgery | Development and progression | Bladder cancer | Diseases | Index Medicus | Abridged Index Medicus
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Cell reports (Cambridge), ISSN 2211-1247, 03/2017, Volume 18, Issue 12, pp. 2893 - 2906
kidney cancer | PBRM1 | ccRCC | mouse tumor model | genetics | STAT3 | VHL | HIF1 | MTOR | epigenetics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Kidney Neoplasms - genetics | Kidney - pathology | Humans | Gene Expression Regulation, Neoplastic | Carcinoma, Renal Cell - genetics | Hydronephrosis - genetics | Gene Expression Profiling | Kidney Neoplasms - metabolism | Kidney - metabolism | HMGB Proteins - deficiency | Hydronephrosis - pathology | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Gene Deletion | HMGB Proteins - metabolism | Integrases - metabolism | Transcription, Genetic | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | STAT3 Transcription Factor - metabolism | Signal Transduction | Carcinoma, Renal Cell - pathology | Oxidative Phosphorylation | Nuclear Proteins - metabolism | Down-Regulation - genetics | Mechanistic Target of Rapamycin Complex 1 - metabolism | Transcription Factors - metabolism | Carcinoma, Renal Cell - metabolism | Animals | Kidney Neoplasms - pathology | Mice | Index Medicus
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