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American Journal of Physiology, ISSN 0363-6135, 11/2018, Volume 315, Issue 5, p. H1353
The prevalence of obesity is increasing worldwide. Obesity-related metabolic disorders are at the center stage to the development of heart disease, stroke,... 
Obesity | Stroke | Cytokines | Developmental stages | Diabetes mellitus | Cardiovascular disease | Inflammation | Diabetes mellitus (non-insulin dependent) | Heart diseases | Coronary artery disease | Metabolic disorders | Cancer
Journal Article
American journal of physiology. Heart and circulatory physiology, ISSN 0363-6135, 09/2019, Volume 317, Issue 4, pp. H790 - H792
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 04/2019, Volume 234, Issue 4, pp. 3910 - 3920
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 10/2018, Volume 315, Issue 5, pp. H1353 - H1355
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 12/2018, Volume 104, Issue 6, pp. 1173 - 1186
Inflammation‐limiting nonsteroidal pain relievers magnify myocardial infarction (MI) incidences and increase re‐admission events in heart failure (HF)... 
leukocytes | inflammation | resolution of inflammation | myocardial infarction | CHRONIC HEART-FAILURE | CYCLOOXYGENASE-2 | FATTY-ACIDS | IMMUNOLOGY | ASPIRIN | ATORVASTATIN | CELL BIOLOGY | OBESITY | THERAPY | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | DISEASE | HEMATOLOGY
Journal Article
Metabolism, ISSN 0026-0495, 07/2019, Volume 96, pp. 22 - 32
After myocardial infarction (MI), delayed progression or reversal of cardiac remodeling is a prime target to limit advanced chronic heart failure (HF).... 
Heart failure | Leukocytes | Metabolites | Resolution of inflammation | Lipid mediators | Metabolic signaling | MYOCARDIAL-INFARCTION | ACIDS | MECHANISMS | OBESITY | INFLAMMATION | DISEASE | DYSREGULATION | ENDOCRINOLOGY & METABOLISM | INFECTION | DYSFUNCTION | MEDIATORS | Membrane lipids | Enzymes | Ischemia | Analysis | Sphingolipids | Biogenic amines | Heart attack
Journal Article
Biotechnology Advances, ISSN 0734-9750, 07/2018, Volume 36, Issue 4, p. 935
Fatty acid drug discovery (FADD) is defined as the identification of novel, specialized bioactive mediators that are derived from fatty acids and have precise... 
Target recognition | Neutrophils | Organs | Homeostasis | Lipids | Inflammation | Pharmacology | Metabolism | Fatty acids | Biological activity | Receptors | Biomolecules | Transformations | Drug therapy | Injuries
Journal Article
American Journal of Physiology, ISSN 0363-6135, 02/2018, Volume 314, Issue 2, p. H255
Heart failure (HF) secondary to myocardial infarction (MI) is linked to kidney complications that comprise cellular, structural, functional, and survival... 
Myocardial infarction | Heart | Networks | Remodeling | Rodents | Bioindicators | Heart diseases | Function analysis | Heart failure | Spleen | Echocardiography | Cell survival | Kidneys | Complications | Inflammation | Histology | Functional analysis | Pathology | Collagen | Myocardium | Biomarkers | Mice | Infarction | Kidney diseases | Ventricle | Cellular structure | Structure-function relationships
Journal Article
American Journal of Physiology, ISSN 0363-6135, 11/2018, Volume 315, Issue 5, p. H1091
Doxorubicin (DOX) is a widely used drug for cancer treatment as a chemotherapeutic agent. However, the cellular and integrative mechanism of DOX-induced... 
Heart | Toxicity | Homeostasis | Prostaglandin E2 | Red pulp | Macrophages | Doxorubicin | Contraction | Pulp | Chronic exposure | Prostaglandin endoperoxide synthase | Tissue | Spleen | Cytokines | Organs | Inflammation | Cachexia | Prescription drugs | Chemotherapy | Liquid oxygen | Myocardium | Mice | Ventricle | Lipoxygenase | Chemokines | Cancer | Apoptosis
Journal Article
American Journal of Physiology, ISSN 0363-6135, 09/2018, Volume 315, Issue 3, p. H522
The generation of big data has enabled systems-level dissections into the mechanisms of cardiovascular pathology. Integration of genetic, proteomic, and... 
Heart | Myocardial infarction | Data points | Integration | Heart attacks | Redundancy | Community participation | Cardiovascular disease | Cardiovascular pathology | Data bases | Massive data points | Community involvement | Databases | Data management | Rodents | Quality control | Mice | Infarction | Quality assessment | Ventricle | Laboratory animals
Journal Article
American Journal of Physiology, ISSN 0363-6135, 07/2017, Volume 313, Issue 1, p. H89
The metabolic transformation of fatty acids to form oxylipids using 12/15-lipoxygenase (LOX) can promote either resolving or nonresolving inflammation.... 
Leucocytes | Heart attacks | Collagen | Coronary artery | Lipids | Kinetics | Macrophages | Fatty acids
Journal Article
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue Suppl_1 Suppl 1, pp. A12625 - A12625
IntroductionAfter myocardial infarction (MI) self-healing is prominent in mice but not in humans. MI-induced innate inflammatory and resolving response is... 
Journal Article
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue Suppl_1 Suppl 1, pp. A16952 - A16952
Introduction12/15lipoxygenase (12/15LOX) metabolites and cyclooxygenase-2(COX-2)-derived prostaglandin E2 (PGE2) are key mediators of the inflammatory response... 
Journal Article
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue Suppl_1 Suppl 1, pp. A19012 - A19012
IntroductionThe lipid metabolizing enzyme 12/15lipoxygenase (12/15LOX) induces pro-inflammatory responses that may increase cardiovascular and renal... 
Journal Article
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