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by Fuchsberger, Christian and Flannick, Jason and Teslovich, Tanya M and Mahajan, Anubha and Agarwala, Vineeta and Gaulton, Kyle J and Ma, Clement and Fontanillas, Pierre and Moutsianas, Loukas and McCarthy, Davis J and Rivas, Manuel A and Perry, John R. B and Sim, Xueling and Blackwell, Thomas W and Robertson, Neil R and Rayner, N. William and Cingolani, Pablo and Locke, Adam E and Fernandez Tajes, Juan and Highland, Heather M and Dupuis, Josee and Chines, Peter S and Lindgren, Cecilia M and Hartl, Christopher and Jackson, Anne U and Chen, Han and Huyghe, Jeroen R and van de Bunt, Martijn and Pearson, Richard D and Kumar, Ashish and Müller-Nurasyid, Martina and Grarup, Niels and Stringham, Heather M and Gamazon, Eric R and Lee, Jaehoon and Chen, Yuhui and Scott, Robert A and Below, Jennifer E and Chen, Peng and Huang, Jinyan and Go, Min Jin and Stitzel, Michael L and Pasko, Dorota and Parker, Stephen C. J and Varga, Tibor V and Green, Todd and Beer, Nicola L and Day-Williams, Aaron G and Ferreira, Teresa and Fingerlin, Tasha and Horikoshi, Momoko and Hu, Cheng and Huh, Iksoo and Ikram, Mohammad Kamran and Kim, Bong-Jo and Kim, Yongkang and Kim, Young Jin and Kwon, Min-Seok and Lee, Juyoung and Lee, Selyeong and Lin, Keng-Han and Maxwell, Taylor J and Nagai, Yoshihiko and Wang, Xu and Welch, Ryan P and Yoon, Joon and Zhang, Weihua and Barzilai, Nir and Voight, Benjamin F and Han, Bok-Ghee and Jenkinson, Christopher P and Kuulasmaa, Teemu and Kuusisto, Johanna and Manning, Alisa and Ng, Maggie C. Y and Palmer, Nicholette D and Balkau, Beverley and Stancáková, Alena and Abboud, Hanna E and Boeing, Heiner and Gieaitis, Vilmantas and Prabhakaran, Dorairaj and Gottesman, Omri and Scott, James and Carey, Jason and Kwan, Phoenix and Grant, George and Smith, Joshua D and Neale, Benjamin M and Purcell, Shaun and Butterworth, Adam S and Howson, Joanna M. M and Lee, Heung Man and Lu, Yingchang and Kwak, Soo-Heon and Zhao, Wei and Danesh, John and Lam, Vincent K. L and Park, Kyong Soo and Saleheen, Danish and ... and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2016, Volume 536, Issue 7614, pp. 41 - +
Journal Article
Cultural studies, ISSN 0950-2386, 01/2001, Volume 15, Issue 1, pp. 161 - 172
Journal Article
by Hale, A
Cultural Studies, ISSN 0950-2386, 01/2001, Volume 15, Issue 1, pp. 161 - 172
Constructs a framework for inquiry about the role of the servant class in the works of Lady Augusta Gregory and Jessie Redmon Fauset. Irish writer Lady... 
Journal Article
Nature, ISSN 0028-0836, 11/2017, Volume 551, Issue 7681, pp. 457 - +
Journal Article
by Knijnenburg, Theo A and Wang, Linghua and Zimmermann, Michael T and Chambwe, Nyasha and Gao, Galen F and Cherniack, Andrew D and Fan, Huihui and Shen, Hui and Way, Gregory P and Greene, Casey S and Liu, Yuexin and Akbani, Rehan and Feng, Bin and Donehower, Lawrence A and Miller, Chase and Shen, Yang and Karimi, Mostafa and Chen, Haoran and Kim, Pora and Jia, Peilin and Shinbrot, Eve and Zhang, Shaojun and Liu, Jianfang and Hu, Hai and Bailey, Matthew H and Yau, Christina and Wolf, Denise and Zhao, Zhongming and Weinstein, John N and Li, Lei and Ding, Li and Mills, Gordon B and Laird, Peter W and Wheeler, David A and Shmulevich, Ilya and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Zhining and Yang, Liming and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Chudamani, Sudha and Liu, Jia and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Zhang, Hailei and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Liu, Yuexin and Miller, Michael and Reynolds, Sheila and Shmulevich, Ilya and Thorsson, Vesteinn and Zhang, Wei and Akbani, Rehan and Broom, Bradley M and Hegde, Apurva M and Ju, Zhenlin and Kanchi, Rupa S and Korkut, Anil and Li, Jun and Liang, Han and Ling, Shiyun and Liu, Wenbin and Lu, Yiling and Mills, Gordon B and Ng, Kwok-Shing and Rao, Arvind and Ryan, Michael and Wang, Jing and Weinstein, John N and Zhang, Jiexin and Abeshouse, Adam and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 1, pp. 239 - 254.e6
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 05/2016, Volume 23, Issue 6, pp. 520 - 577
In the late 1980s, reports emerged describing experimental antibacterial quinolones having significant potency against eukaryotic Type II topoisomerases (topo... 
Topo IV | Quinolone | Paul Ehrlich | Etoposide | G quadruplex | Selectivity | Antibacterial | Cytotoxic | Doxorubicin | Topo II | Vosaroxin | Gyrase | Antitumor | Topoisomerase | Quarfloxin | Fluoroquinolone | Magic bullet | Anticancer | selectivity | vosaroxin | antitumor | topo IV | antibacterial | CELL-CYCLE ARREST | RESISTANT STAPHYLOCOCCUS-AUREUS | anticancer | 7-SUBSTITUTED 1,4-DIHYDRO-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS | gyrase | EXPLOITING MECHANISTIC DIFFERENCES | quarfloxin | PHARMACOLOGY & PHARMACY | doxorubicin | topo II | cytotoxic | TELOMERIC G-QUADRUPLEXES | CHEMISTRY, MEDICINAL | fluoroquinolone | BIOCHEMISTRY & MOLECULAR BIOLOGY | SIDE-EFFECT RELATIONSHIPS | ACUTE MYELOID-LEUKEMIA | magic bullet | MAMMALIAN TOPOISOMERASE-II | topoisomerase | etoposide | ANTIBODY-BASED THERAPIES | DRUG-INTERACTION DOMAINS | Neoplasms - metabolism | DNA Topoisomerases, Type II - metabolism | Antibiotics, Antineoplastic - pharmacology | Humans | Models, Molecular | Drug Discovery - methods | Quinolones - pharmacology | Topoisomerase II Inhibitors - pharmacology | Topoisomerase II Inhibitors - therapeutic use | Neoplasms - drug therapy | Anti-Bacterial Agents - therapeutic use | Animals | Quinolones - chemistry | Antibiotics, Antineoplastic - chemistry | Antibiotics, Antineoplastic - therapeutic use | Signal Transduction - drug effects | Topoisomerase II Inhibitors - chemistry | Anti-Bacterial Agents - chemistry | Quinolones - therapeutic use | Anti-Bacterial Agents - pharmacology
Journal Article
The Journal of Physiology, ISSN 0022-3751, 08/2011, Volume 589, Issue 16, pp. 3983 - 3994
Journal Article
Cell, ISSN 0092-8674, 07/2012, Volume 150, Issue 2, pp. 251 - 263
Journal Article