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Nature Communications, ISSN 2041-1723, 02/2015, Volume 6, Issue 1, p. 6282
RIPK3 and its substrate MLKL are essential for necroptosis, a lytic cell death proposed to cause inflammation via the release of intracellular molecules.... 
RHEUMATOID-ARTHRITIS | NECROPTOSIS | MULTIDISCIPLINARY SCIENCES | DOMAIN-LIKE PROTEIN | MIXED LINEAGE KINASE | PROGRAMMED NECROSIS | DEPENDENT APOPTOSIS | CASPASE-8 | TNF-ALPHA | NF-KAPPA-B | INNATE IMMUNITY
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4976 - 13
Intrinsic apoptosis is critical to prevent tumor formation and is engaged by many anti-cancer agents to eliminate tumor cells. BAX and BAK, the two essential... 
BCL-2 | ACTIVATION | MULTIDISCIPLINARY SCIENCES | MITOCHONDRIA | INHIBITOR | PROTEINS | ANION CHANNEL 2 | BCL-X(L) | BH3 DOMAIN | CELL-DEATH | REQUIREMENT | CRISPR | Bax protein | Tumor cells | Genomes | Anticancer properties | Mitochondria | Clonal deletion | Cell death | Deletion | Ion channels | Tumors | Apoptosis | Cancer
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 2018, Volume 26, Issue 5, pp. 877 - 889
RIPK1 is an essential downstream component of many pattern recognition and death receptors. RIPK1 can promote the activation of caspase-8 induced apoptosis and... 
NECROSIS-FACTOR RECEPTOR | ACTIVATION | HOMEOSTASIS | NECROPTOSIS | INHIBITION | PHOSPHORYLATION | INFLAMMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CASPASE-8 | FADD | CELL-DEATH | CELL BIOLOGY | Tumor necrosis factor receptors | Neonates | Splenomegaly | Caspase | c-FLIP protein | Lethality | Pattern recognition | Thymus | FADD protein | Caspase-8 | Clonal deletion | Intestine | Cell death | Death receptors | Apoptosis
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 07/2017, Volume 20, Issue 3, pp. 668 - 682
Journal Article
Journal Article
Cell, ISSN 0092-8674, 05/2014, Volume 157, Issue 5, pp. 1175 - 1188
Journal Article
Sexually Transmitted Infections, ISSN 1368-4973, 07/2017, Volume 93, Issue Suppl 2, p. A22
IntroductionRapid Point-Of-Care Tests (POCTs) for Chlamydia trachomatis (CT) may reduce onward transmission and reproductive sexual health (RSH) sequelae by... 
Chlamydia
Journal Article
by Sawcer, Stephen and Hellenthal, Garrett and Pirinen, Matti and Spencer, Chris C.A and Patsopoulos, Nikolaos A and Moutsianas, Loukas and Dilthey, Alexander and Su, Zhan and Freeman, Colin and Hunt, Sarah E and Edkins, Sarah and Gray, Emma and Booth, David R and Potter, Simon C and Goris, An and Band, Gavin and Oturai, Annette Bang and Strange, Amy and Saarela, Janna and Bellenguez, Céline and Fontaine, Bertrand and Gillman, Matthew and Hemmer, Bernhard and Gwilliam, Rhian and Zipp, Frauke and Jayakumar, Alagurevathi and Martin, Roland and Leslie, Stephen and Hawkins, Stanley and Giannoulatou, Eleni and D'Alfonso, Sandra and Blackburn, Hannah and Boneschi, Filippo Martinelli and Liddle, Jennifer and Harbo, Hanne F and Perez, Marc L and Spurkland, Anne and Waller, Matthew J and Mycko, Marcin P and Ricketts, Michelle and Comabella, Manuel and Hammond, Naomi and Kockum, Ingrid and McCann, Owen T and Ban, Maria and Whittaker, Pamela and Kemppinen, Anu and Weston, Paul and Hawkins, Clive and Widaa, Sara and Zajicek, John and Dronov, Serge and Robertson, Neil and Bumpstead, Suzannah J and Barcellos, Lisa F and Ravindrarajah, Rathi and Abraham, Roby and Alfredsson, Lars and Ardlie, Kristin and Aubin, Cristin and Baker, Amie and Baker, Katharine and Baranzini, Sergio E and Bergamaschi, Laura and Bergamaschi, Roberto and Bernstein, Allan and Berthele, Achim and Boggild, Mike and Bradfield, Jonathan P and Brassat, David and Broadley, Simon A and Buck, Dorothea and Butzkueven, Helmut and Capra, Ruggero and Carroll, William M and Cavalla, Paola and Celius, Elisabeth G and Cepok, Sabine and Chiavacci, Rosetta and Clerget-Darpoux, Françoise and Clysters, Katleen and Comi, Giancarlo and Cossburn, Mark and Cournu-Rebeix, Isabelle and Cox, Mathew B and Cozen, Wendy and Cree, Bruce A.C and Cross, Anne H and Cusi, Daniele and Daly, Mark J and Davis, Emma and De Bakker, Paul I.W and Debouverie, Marc and D'Hooghe, Marie Beatrice and Dixon, Katherine and Dobosi, Rita and Dubois, Bénédicte and Ellinghaus, David and Elovaara, Irina and Esposito, Federica and ... and Wellcome Trust Case Control Consor and Int Multiple Sclerosis Genetics Co and Wellcome Trust Case Control Consortium 2 and International Multiple Sclerosis Genetics Consortium and The International Multiple Sclerosis Genetics Consortium & The Wellcome Trust Case Control Consortium 2 and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Molekylär medicin and Uppsala universitet and Institutionen för medicinska vetenskaper
Nature, ISSN 0028-0836, 08/2011, Volume 476, Issue 7359, pp. 214 - 219
Journal Article