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animals (23) 23
male (23) 23
rats (22) 22
endocrinology & metabolism (17) 17
aldehyde reductase - antagonists & inhibitors (12) 12
humans (11) 11
cells, cultured (10) 10
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complications (7) 7
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peripheral-nerve (7) 7
casings or constructional details of electric apparatus (6) 6
diabetes (6) 6
electric techniques not otherwise provided for (6) 6
electricity (6) 6
manufacture of assemblages of electrical components (6) 6
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rats, sprague-dawley (6) 6
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basic electric elements (5) 5
blood-flow (5) 5
care and treatment (5) 5
diabetes mellitus, experimental - drug therapy (5) 5
diabetes mellitus, experimental - physiopathology (5) 5
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female (5) 5
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sorbitol - metabolism (5) 5
aldose reductase (4) 4
angiogenesis (4) 4
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blood glucose - metabolism (4) 4
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diabetic neuropathies - physiopathology (4) 4
diabetic retinopathy (4) 4
endothelial-cells (4) 4
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glucose - pharmacology (4) 4
insulin (4) 4
insulin-resistance (4) 4
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platelet aggregation - drug effects (4) 4
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articles (3) 3
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deoxyglucose - metabolism (3) 3
diabetes mellitus (3) 3
diabetes mellitus, experimental - complications (3) 3
diabetes mellitus, type 2 - physiopathology (3) 3
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dna - biosynthesis (3) 3
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enzyme inhibitors - therapeutic use (3) 3
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medicine, research & experimental (3) 3
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motor neurons - drug effects (3) 3
muscle, smooth, vascular - metabolism (3) 3
neural conduction - physiology (3) 3
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sucrose (3) 3
transplantation (3) 3
3-deoxyglucosone (2) 2
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Patent
European Journal of Pharmacology, ISSN 0014-2999, 1995, Volume 294, Issue 1, pp. 207 - 214
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 1996, Volume 45, Issue 3, pp. 361 - 366
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 11/1997, Volume 273, Issue 5, pp. 965 - 971
To investigate the role of increased polyol pathway activity and hemodynamic deficits in the pathogenesis of diabetic retinopathy in non-insulin-dependent... 
[5-(3- thienyl) tetrazol-1-yl] acetic acid monohydrate | Cilostazol | Platelet aggregation | Polyol pathway | Red blood cell 2,3-diphosphoglycerate | Otsuka Long-Evans Tokushima fatty rats | polyol pathway | CELLS | PHYSIOLOGY | ABNORMALITIES | red blood cell 2,3-diphosphoglycerate | TAT | AORTA | BLOOD-FLOW | PREVENTS | platelet aggregation | INSULIN | NEUROPATHY | NICERITROL | ENDOCRINOLOGY & METABOLISM | cilostazol | [5-(3-thienyl)tetrazol-1-yl]acetic acid monohydrate | Retina - drug effects | Retina - metabolism | Tetrazoles - pharmacology | Humans | Body Weight - drug effects | Male | Insulin - blood | Rats, Inbred Strains | Fructose - metabolism | Diabetic Retinopathy - physiopathology | Sorbitol - metabolism | Electroretinography - drug effects | Platelet Aggregation Inhibitors - pharmacology | Platelet Aggregation - drug effects | 2,3-Diphosphoglycerate - metabolism | Diabetes Mellitus, Experimental - physiopathology | Aldehyde Reductase - antagonists & inhibitors | Dietary Sucrose - pharmacology | Enzyme Inhibitors - pharmacology | Rats | Thiophenes - pharmacology | Blood Glucose - drug effects | Animals | Diabetes Mellitus, Type 2 - physiopathology | Anticoagulants - pharmacology | Triglycerides - blood | Blood Glucose - metabolism | Type 2 diabetes | Diabetic retinopathy | Care and treatment | Sucrose | Development and progression | Anticoagulants (Medicine) | Polyols | Retinal diseases | Aldose reductase | Physiological aspects | Diagnosis | Health aspects
Journal Article
Life Sciences, ISSN 0024-3205, 1997, Volume 60, Issue 21, pp. 1847 - 1857
In an animal model of human non-insulin dependent diabetes mellitus (NIDDM), Otsuka Long-Evans Tokushima Fatty (OLETF) rats were fed with sucrose for 8 weeks... 
nerve Wood flow | polyol pathway | aldose reductase inhibitor | diabetic neuropathy | motor nerve conduction velocity | sucrose | Otsuka Long-Evans Tokushima fatty rat | coefficient of variance of R-R interval | platelet aggregation | Motor nerve conduction velocity | Sucrose | Aldose reductase inhibitor | Diabetic neuropathy | Platelet aggregation | Polyol pathway | Nerve blood flow | Coefficient of variance of R-R interval | FILTRATION CHANGES | MEDICINE, RESEARCH & EXPERIMENTAL | NERVE-CONDUCTION-VELOCITY | PLATELET-AGGREGATION | MELLITUS | PIGMENT EPITHELIAL-CELLS | SCIATIC-NERVE | nerve blood flow | PERIPHERAL NEUROPATHY | PHARMACOLOGY & PHARMACY | RICH DIET | COMPLICATIONS | BLOOD | Sciatic Nerve - chemistry | Thiophenes - therapeutic use | Body Weight | Tetrazoles - pharmacology | Male | Insulin - blood | Sciatic Nerve - blood supply | Regional Blood Flow - drug effects | Lipids - blood | Platelet Aggregation Inhibitors - pharmacology | Platelet Aggregation - drug effects | Platelet Aggregation Inhibitors - therapeutic use | Diabetes Mellitus, Type 2 - complications | Diabetic Neuropathies - physiopathology | Disease Models, Animal | Sucrose - administration & dosage | Aldehyde Reductase - antagonists & inhibitors | Blood Glucose - analysis | Enzyme Inhibitors - pharmacology | Rats | Thiophenes - pharmacology | Diabetic Neuropathies - drug therapy | Enzyme Inhibitors - therapeutic use | Animals | Tetrazoles - therapeutic use | Diabetic Neuropathies - metabolism | Polymers - metabolism
Journal Article
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 03/1997, Volume 75, Issue 3, pp. 179 - 184
Journal Article
American journal of physiology. Endocrinology and metabolism, 11/1997, Volume 273, Issue 5, p. E965
To investigate the role of increased polyol pathway activity and hemodynamic deficits in the pathogenesis of diabetic retinopathy in non-insulin-dependent... 
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 1998, Volume 287, Issue 3, pp. 897 - 902
Journal Article
Life Sciences, ISSN 0024-3205, 1999, Volume 64, Issue 25, pp. 2317 - 2325
Journal Article
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