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by Helgadottir, Anna, MD, PhD and Gretarsdottir, Solveig, PhD and Thorleifsson, Gudmar, PhD and Holm, Hilma, MD and Patel, Riyaz S., MD and Gudnason, Thorarinn, MD, PhD and Jones, Gregory T., PhD and van Rij, Andre M., MD and Eapen, Danny J., MD and Baas, Annette F., PhD and Tregouet, David-Alexandre, PhD and Morange, Pierre-Emmanuel, MD and Emmerich, Joseph, MD, PhD and Lindblad, Bengt, MD, PhD and Gottsäter, Anders, MD, PhD and Kiemeny, Lambertus A., PhD and Lindholt, Jes S., MD, PhD and Sakalihasan, Natzi, MD, PhD and Ferrell, Robert E., PhD and Carey, David J., PhD and Elmore, James R., MD and Tsao, Philip S., PhD and Grarup, Niels, MD, PhD and Jørgensen, Torben, MD, DMSci and Witte, Daniel R., MD, PhD and Hansen, Torben, MD, PhD and Pedersen, Oluf, MD, DMSci and Pola, Roberto, MD, PhD and Gaetani, Eleonora, MD and Magnadottir, Hulda B., MD and Wijmenga, Cisca, PhD and Tromp, Gerard, PhD and Ronkainen, Antti, MD, PhD and Ruigrok, Ynte M., MD and Blankensteijn, Jan D and Mueller, Thomas, MD and Wells, Philip S., MD and Corral, Javier, PhD and Soria, Jose Manuel, PhD and Souto, Juan Carlos, MD, PhD and Peden, John F., PhD and Jalilzadeh, Shapour, MD, PhD and Mayosi, Bongani M., DPhil and Keavney, Bernard, MD and Strawbridge, Rona J., PhD and Sabater-Lleal, Maria, PhD and Gertow, Karl, PhD and Baldassarre, Damiano, PhD and Nyyssönen, Kristiina, PhD and Rauramaa, Rainer, MD, PhD and Smit, Andries J., MD, PhD and Mannarino, Elmo, MD and Giral, Philippe, MD and Tremoli, Elena, PhD and de Faire, Ulf, MD, PhD and Humphries, Steve E., PhD and Hamsten, Anders, MD, PhD and Haraldsdottir, Vilhelmina, MD and Olafsson, Isleifur, MD, PhD and Magnusson, Magnus K., MD and Samani, Nilesh J., MD and Levey, Allan I., MD, PhD and Markus, Hugh S., MD and Kostulas, Konstantinos, MD, PhD and Dichgans, Martin, MD and Berger, Klaus, MD and Kuhlenbäumer, Gregor, MD and Ringelstein, E. Bernd, MD and Stoll, Monika, PhD and Seedorf, Udo, PhD and Rothwell, Peter M., MD, PhD and Powell, Janet T., MD and Kuivaniemi, Helena, MD, PhD and Onundarson, Pall T., MD and Valdimarsson, Einar, MD and Matthiasson, Stefan E., MD, PhD and Gudbjartsson, Daniel F., PhD and Thorgeirsson, Guðmundur, MD, PhD and Quyyumi, Arshed A., MD and Watkins, Hugh, MD, PhD and Farrall, Martin, MD and Thorsteinsdottir, Unnur, PhD and Stefansson, Kari, MD, PhD and Lund University and Vascular Diseases - Clinical Research and Vaskulära sjukdomar - kliniska studier and Lunds universitet
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2012, Volume 60, Issue 8, pp. 722 - 729
Objectives The purpose of this study is investigate the effects of variants in the apolipoprotein(a) gene ( LPA ) on vascular diseases with different... 
Cardiovascular | Internal Medicine | atherosclerosis | genetic | association | thrombosis | lipoprotein(a) | INTIMA-MEDIA THICKNESS | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | METAANALYSIS | MYOCARDIAL-INFARCTION | VASCULAR-DISEASE | WOMEN | PERIPHERAL ARTERIAL-DISEASE | ISCHEMIC-STROKE | SEVERITY | Severity of Illness Index | Myocardial Infarction - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Apolipoproteins A - genetics | Angiography | Carotid Intima-Media Thickness | Intracranial Aneurysm - genetics | Atherosclerosis - genetics | Humans | Risk Factors | Brain Ischemia - genetics | African Americans - genetics | Linear Models | Logistic Models | Aortic Aneurysm, Abdominal - genetics | Stroke - genetics | Venous Thromboembolism - genetics | Peripheral Arterial Disease - genetics | Age of Onset | Coronary Artery Disease - genetics | Polymorphism, Single Nucleotide | Odds Ratio | Medical colleges | Neurosciences | Stock options | Genes | Aneurysms | Coronary heart disease | Biometry | Lipoprotein A | Anopheles | Atherosclerosis | Medical genetics | Genetic research | Genetic aspects | Diabetes | Thromboembolism | Cardiology | Public health | Dementia | Stroke | Medical imaging | Values | Cardiovascular disease | Apolipoproteins | Thrombosis | Studies | Confidence intervals | Coronary vessels | Blood pressure | Drug therapy | Age | Methods | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin
Journal Article
by Holmes, Michael V., MSc and Simon, Tabassome, MD, PhD and Exeter, Holly J., PhD and Folkersen, Lasse, PhD and Asselbergs, Folkert W., MD, PhD and Guardiola, Montse, PhD and Cooper, Jackie A., MSc and Palmen, Jutta, MSc and Hubacek, Jaroslav A., DSc, PhD and Carruthers, Kathryn F., MPhil and Horne, Benjamin D., PhD, MPH and Brunisholz, Kimberly D., MST and Mega, Jessica L., MD, MPH and van Iperen, Erik P.A., MSc and Li, Mingyao, PhD and Leusink, Maarten, MSc and Trompet, Stella, PhD and Verschuren, Jeffrey J.W., MD, MSc and Hovingh, G. Kees, MD, PhD and Dehghan, Abbas, MD, PhD and Nelson, Christopher P., PhD and Kotti, Salma, PharmD, PhD and Danchin, Nicolas, MD, PhD and Scholz, Markus, PhD and Haase, Christiane L., PhD and Rothenbacher, Dietrich, MD and Swerdlow, Daniel I., MBBS, PhD and Kuchenbaecker, Karoline B., Dipl Psych, MSc and Staines-Urias, Eleonora, MD, MSc and Goel, Anuj, MSc and van 't Hooft, Ferdinand, MD, PhD and Gertow, Karl, PhD and de Faire, Ulf, MD, PhD and Panayiotou, Andrie G., PhD and Tremoli, Elena, PhD and Baldassarre, Damiano, PhD and Veglia, Fabrizio, PhD and Holdt, Lesca M., MD, PhD and Beutner, Frank, MD, PhD and Gansevoort, Ron T., MD, PhD and Navis, Gerjan J., MD, PhD and Mateo Leach, Irene, PhD and Breitling, Lutz P., MD and Brenner, Hermann, MD, MPH and Thiery, Joachim, MD, MBA and Dallmeier, Dhayana, MD and Franco-Cereceda, Anders, MD, PhD and Boer, Jolanda M.A., PhD and Stephens, Jeffrey W., PhD and Hofker, Marten H., PhD and Tedgui, Alain, PhD and Hofman, Albert, MD, PhD and Uitterlinden, André G., PhD and Adamkova, Vera, MD, PhD and Pitha, Jan, MD, PhD and Onland-Moret, N. Charlotte, PhD and Cramer, Maarten J., MD, PhD and Nathoe, Hendrik M., MD, PhD and Spiering, Wilko, MD, PhD and Klungel, Olaf H., PharmD, PhD and Kumari, Meena, PhD and Whincup, Peter H and Morrow, David A., MD and Braund, Peter S., MSc and Hall, Alistair S., PhD and Olsson, Anders G., MD, PhD and Doevendans, Pieter A., MD, PhD and Trip, Mieke D., MD, PhD and Tobin, Martin D., PhD and Hamsten, Anders, PhD and Watkins, Hugh, PhD and Koenig, Wolfgang, MD and Nicolaides, Andrew N., PhD and Teupser, Daniel, MD, PhD and Day, Ian N.M and Carlquist, John F., PhD and Gaunt, Tom R., PhD and Ford, Ian, PhD and Sattar, Naveed and Tsimikas, Sotirios, MD and Schwartz, Gregory G., MD PhD and Lawlor, Debbie A., PhD and Morris, Richard W., PhD and Sandhu, Manjinder S., PhD and Poledne, Rudolf, PhD and Maitland-van der Zee, Anke H., PhD and Khaw, Kay-Tee, MBBChir and Keating, Brendan J., PhD and van der Harst, Pim, MD, PhD and Price, Jackie F., MD and Mehta, Shamir R., MD, MSc and Yusuf, Salim, MBBS, DPhil and Witteman, Jaqueline C.M., PhD and Franco, Oscar H., MD, PhD and Jukema, J. Wouter, MD, PhD and de Knijff, Peter, PhD and Tybjaerg-Hansen, Anne, MD, DMSc and Rader, Daniel J., MD and Farrall, Martin, MD, PhD and Samani, Nilesh J., MD and ...
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 62, Issue 21, pp. 1966 - 1976
Objectives This study sought to investigate the role of secretory phospholipase A2 (sPLA2 )-IIA in cardiovascular disease. Background Higher circulating levels... 
Cardiovascular | Internal Medicine | drug development | epidemiology | genetics | cardiovascular diseases | Mendelian randomization | Studies | Cardiovascular disease | Heart attacks | Drug therapy | Mortality | Cholesterol
Journal Article
Journal Article
Diabetes Care, ISSN 0149-5992, 10/2003, Volume 26, Issue 10, pp. 2770 - 2776
Journal Article
by Swerdlow, Daniel I, Dr and Preiss, David, Dr and Kuchenbaecker, Karoline B, MSc and Holmes, Michael V, PhD and Engmann, Jorgen E L, MSc and Shah, Tina, PhD and Sofat, Reecha, MD and Stender, Stefan, MD and Johnson, Paul C D, PhD and Scott, Robert A, PhD and Leusink, Maarten, MSc and Verweij, Niek, MD and Sharp, Stephen J, MSc and Guo, Yiran, PhD and Giambartolomei, Claudia, MSc and Chung, Christina, MSc and Peasey, Anne, PhD and Amuzu, Antoinette, MSc and Li, KaWah, MSc and Palmen, Jutta, MSc and Howard, Philip, MSc and Cooper, Jackie A, MSc and Drenos, Fotios, PhD and Li, Yun R, BSc and Lowe, Gordon, Prof and Gallacher, John, PhD and Stewart, Marlene C W, PhD and Tzoulaki, Ioanna, PhD and Buxbaum, Sarah G, PhD and van der A, Daphne L, PhD and Forouhi, Nita G, MRCP and Onland-Moret, N Charlotte, PhD and van der Schouw, Yvonne T, Prof and Schnabel, Renate B, MD and Hubacek, Jaroslav A, PhD and Kubinova, Ruzena, MD and Baceviciene, Migle, MD and Tamosiunas, Abdonas, Prof and Pajak, Andrzej, Prof and Topor-Madry, Romanvan, MD and Stepaniak, Urszula, PhD and Malyutina, Sofia, Prof and Baldassarre, Damiano, PhD and Sennblad, Bengt, PhD and Tremoli, Elena, Prof and de Faire, Ulf, Prof and Veglia, Fabrizio, PhD and Ford, Ian, Prof and Jukema, J Wouter, Prof and Westendorp, Rudi G J, Prof and de Borst, Gert Jan, MD and de Jong, Pim A, MD and Algra, Ale, Prof and Spiering, Wilko, MD and der Zee, Anke H Maitland-van, PhD and Klungel, Olaf H, PharmD and de Boer, Anthonius, Prof and Doevendans, Pieter A, Prof and Eaton, Charles B, Prof and Robinson, Jennifer G, Prof and Duggan, David, PhD and Kjekshus, John, Prof and Downs, John R, MD and Gotto, Antonio M, MD and Keech, Anthony C, MD and Marchioli, Roberto, MD and Tognoni, Gianni, MD and Sever, Peter S, Prof and Poulter, Neil R, Prof and Waters, David D, MD and Pedersen, Terje R, MD and Amarenco, Pierre, MD and Nakamura, Haruo, MD and McMurray, John J V, Prof and Lewsey, James D, PhD and Chasman, Daniel I, PhD and Ridker, Paul M, MD and Maggioni, Aldo P, Prof and Tavazzi, Luigi, Prof and Ray, Kausik K, Prof and Seshasai, Sreenivasa Rao Kondapally, MD and Manson, JoAnn E, Prof and Price, Jackie F, MD and Whincup, Peter H, Prof and Morris, Richard W, Prof and Lawlor, Debbie A, Prof and Smith, George Davey, Prof and Ben-Shlomo, Yoav, Prof and Schreiner, Pamela J, Prof and Fornage, Myriam, Prof and Siscovick, David S, Prof and Cushman, Mary, MD and Kumari, Meena, PhD and Wareham, Nick J, Prof and Verschuren, W M Monique, PhD and Redline, Susan, Prof and Patel, Sanjay R, MD and Whittaker, John C, Prof and Hamsten, Anders, Prof and Delaney, Joseph A, PhD and ... and MAGIC Consortium and InterAct Consortium and DIAGRAM Consortium
The Lancet, ISSN 0140-6736, 01/2015, Volume 385, Issue 9965, pp. 351 - 361
Journal Article
Diabetes Care, ISSN 0149-5992, 02/2009, Volume 32, Issue 2, p. 317
Peripheral Sensory Neuropathy Associates With Micro- or Macroangiopathy Results from a population-based study of type 2 diabetic patients in Sweden Lars... 
Journal Article
Diabetes Care, ISSN 0149-5992, 09/2003, Volume 26, Issue 9, p. 2575
Effect of Dalteparin on Healing of Chronic Foot Ulcers in Diabetic Patients With Peripheral Arterial Occlusive Disease A prospective, randomized, double-blind,... 
Journal Article
by Joshi, Peter and Esko, Tõnu and Mattsson, Hannele and Eklund, Niina and Gandin, Ilaria and Nutile, T and Jackson, Anne and Schurmann, Claudia and Smith, G.D and Zhang, Weihua and Okada, Yukinori and Stancáková, Alena and Faul, Jessica D and Zhao, Wei and Bartz, Traci M and Concas, M.P and Franceschini, Nora and Enroth, Stefan and Vitart, Veronique and Trompet, Stella and Guo, Xiuqing and Chasman, Daniel and O'Connel, Jeffrey R and Corre, Tanguy and Nongmaithem, Suraj S and Chen, Yuning and Mangino, Massimo and Ruggiero, D and Traglia, Michela and Farmaki, Aliki-Eleni and Kacprowski, Tim and Bjonnes, Anew and Spek, Ashley and Wu, Ying and Giri, Anil K and Yanek, Lisa and Wang, Lihua and Hofer, Edith and Rietveld, Niels and McLeod, Olga and Cornelis, Marilyn and Pattaro, Cristian and Verweij, Niek and Baumbach, Clemens and Abdellaoui, Abdel and Warren, Helen and Vuckovic, gana and Mei, Hao and Bouchard, Claude and Perry, John and Cappellani, Stefania and Mirza, Saira and Benton, Miles C and Broeckel, Ulrich and Medland, Sarah Elizabeth and Lind, Penelope and Malerba, Giovanni and ng, Alexander and Yengo, Loic and Bielak, Lawrence F and Zhi, Degui and Most, Peter and Shriner, Daniel and Mägi, Reedik and Hemani, G and Karaderi, Tugce and Wang, Zhaoming and Liu, Tian and Demuth, Ilja and Zhao, Jing Hua and Meng, Weihua and Lataniotis, Lazaros and Van Der Laan, Sander W and Bradfield, Jonathan and Wood, Anew and Bonnefond, Amélie and Ahluwalia, Tarunveer Singh and Hall, Leanne M and Salvi, Erika and Yazar, Seyhan and Carstensen, Lisbeth and De Haan, Hugoline G and Abney, Mark and Afzal, Uzma and Allison, Matthew and Amin, Najaf and Asselbergs, Folkert W and Bakker, Stephan and Barr, Graham and Baumeister, Sebastian and Benjamin, Daniel J and Bergmann, Sven and Boerwinkle, Eric and Bottinger, Erwin P and Campbell, Archie and Chakravarti, Aravinda and Chan, Yingleong and Chanock, Stephen and Chen, Constance and Chen, Y.-D. Ida and ... and BioBank Japan Project and The BioBank Japan Project and Science for Life Laboratory, SciLifeLab and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Medicinsk genetik och genomik and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
Nature: international weekly journal of science, ISSN 0028-0836, 07/2015, Volume 523, Issue 7561, pp. 459 - 462
textabstractHomozygosity has long been associated with rare, often devastating, Mendelian disorders, and Darwin was one of the first to recognize that... 
INTELLIGENCE | HOMOZYGOSITY | MULTIDISCIPLINARY SCIENCES | ARCHITECTURE | GENETIC-VARIANTS | TRAITS | ASSOCIATION | BLOOD-PRESSURE | Studies | Cognition & reasoning | Disease | Genomics | Cognitive ability | Genomes | Educational attainment | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
by Holmes, Michael V and Simon, Tabassome and Exeter, Holly J and Folkersen, Lasse and Asselbergs, Folkert W and Guardiola, Montse and Cooper, Jackie A and Palmen, Jutta and Hubacek, Jaroslav A and Carruthers, Kathryn F and Horne, Benjamin D and Brunisholz, Kimberly D and Mega, Jessica L and Van Iperen, Erik P. A and Li, Mingyao and Leusink, Maarten and Trompet, Stella and Verschuren, Jeffrey J. W and Hovingh, G. Kees and Dehghan, Abbas and Nelson, Christopher P and Kotti, Salma and Danchin, Nicolas and Scholz, Markus and Haase, Christiane L and Rothenbacher, Dietrich and Swerdlow, Daniel I and Kuchenbaecker, Karoline B and Staines-Urias, Eleonora and Goel, Anuj and van 't Hooft, Ferdinand and Gertow, Karl and de Faire, Ulf and Panayiotou, Anie G and Tremoli, Elena and Baldassarre, Damiano and Veglia, Fabrizio and Holdt, Lesca M and Beutner, Frank and Gansevoort, Ron T and Navis, Gerjan J and Mateo Leach, Irene and Breitling, Lutz P and Brenner, Hermann and Thiery, Joachim and Dallmeier, Dhayana and Franco-Cereceda, Anders and Boer, Jolanda M. A and Stephens, Jeffrey W and Hofker, Marten H and Tedgui, Alain and Hofman, Albert and Uitterlinden, Ane G and Adamkova, Vera and Pitha, Jan and Onland-Moret, N. Charlotte and Cramer, Maarten J and Nathoe, Henik M and Spiering, Wilko and Klungel, Olaf H and Kumari, Meena and Whincup, Peter H and Morrow, David A and Braund, Peter S and Hall, Alistair S and Olsson, Anders G and Doevendans, Pieter A and Trip, Mieke D and Tobin, Martin D and Hamsten, Anders and Watkins, Hugh and Koenig, Wolfgang and Nicolaides, Anew N and Teupser, Daniel and Day, Ian N. M and Carlquist, John F and Gaunt, Tom R and Ford, Ian and Sattar, Naveed and Tsimikas, Sotirios and Schwartz, Gregory G and Lawlor, Debbie A and Morris, Richard W and Sandhu, Manjinder S and Poledne, Rudolf and Maitland-van der Zee, Anke H and Khaw, Kay-Tee and Keating, Brendan J and van der Harst, Pim and Price, Jackie F and Mehta, Shamir R and Yusuf, Salim and Witteman, Jaqueline C. M and Franco, Oscar H and Jukema, J. Wouter and de Knijff, Peter and Tybjaerg-Hansen, Anne and Rader, Daniel J and Farrall, Martin and Samani, Nilesh J and ... and Avdelningen för kardiovaskulär medicin and Endokrinmedicinska kliniken and Linköpings universitet and Institutionen för medicin och hälsa and Hjärt- och Medicincentrum and Östergötlands Läns Landsting and Hälsouniversitetet
Journal of the American College of Cardiology, ISSN 0735-1097, 11/2013, Volume 62, Issue 21, pp. 1966 - 1976
Objectives This study sought to investigate the role of secretory phospholipase A(2) (sPLA(2))-IIA in cardiovascular disease. Background Higher circulating... 
CARDIAC & CARDIOVASCULAR SYSTEMS | EVENTS | METAANALYSIS | drug development | RISK | cardiovascular diseases | Mendelian randomization | ACUTE CORONARY SYNDROME | epidemiology | genetics | ENZYMES | SERUM-LEVELS | INHIBITOR | HEALTHY-MEN | ASSOCIATION | TEKNIKVETENSKAP | Engineering and Technology | Teknik och teknologier | TECHNOLOGY
Journal Article
Circulation, ISSN 0009-7322, 09/1995, Volume 92, Issue 6, p. 1422
Glucose intolerance and hyperinsulinemia are common disturbances in nondiabetic men with premature coronary artery disease (CAD). To investigate the relation... 
Adrenergic beta-Antagonists - pharmacology | Coronary Angiography | Myocardial Infarction - blood | Proinsulin - blood | Glucose Tolerance Test | Humans | Insulin Resistance | Adult | Male | Insulin - blood | Coronary Artery Disease - blood
Journal Article