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Science, ISSN 0036-8075, 6/2010, Volume 328, Issue 5986, pp. 1689 - 1693
Elevated leukocyte cell numbers (leukocytosis), and monocytes in particular, promote atherosclerosis; however, how they become increased is poorly understood.... 
Myeloid cells | Leukocytosis | Transgenic animals | HDL lipoproteins | REPORTS | Atherosclerosis | Transgenes | Macrophages | Lesions | Cholesterols | Progenitor cells | CHOLESTEROL | MULTIDISCIPLINARY SCIENCES | MACROPHAGE ABCA1 | LIPID RAFTS | GENE-EXPRESSION | ATHEROSCLEROSIS | MICE | ACCUMULATION | ABCG1 | HIGH-DENSITY-LIPOPROTEIN | APOLIPOPROTEIN-A-I | Cell Proliferation | Lipoproteins - genetics | Lipoproteins, HDL - metabolism | Apolipoprotein A-I - genetics | Leukocytosis - metabolism | ATP-Binding Cassette Transporters - genetics | Atherosclerosis - therapy | Leukocytosis - therapy | Myeloproliferative Disorders - metabolism | Bone Marrow Transplantation | Leukocytosis - physiopathology | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Hematopoietic Stem Cells - physiology | Mice, Inbred DBA | ATP Binding Cassette Transporter 1 | Multipotent Stem Cells - physiology | ATP Binding Cassette Transporter, Subfamily G, Member 1 | Myeloproliferative Disorders - therapy | Signal Transduction | Atherosclerosis - physiopathology | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Receptors, Interleukin-3 - metabolism | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | Atherosclerosis - metabolism | Macrophages - metabolism | Phenotype | Animals | Myeloid Progenitor Cells - physiology | Myeloproliferative Disorders - physiopathology | Mice | Hypercholesterolemia - metabolism | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Cell proliferation | High density lipoproteins | Physiological aspects | Development and progression | Research | Health aspects | Hematopoietic stem cells | Adenosine triphosphate
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2007, Volume 117, Issue 12, pp. 3900 - 3908
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2012, Volume 122, Issue 4, pp. 1262 - 1270
Individuals with type 2 diabetes have an increased risk of atherosclerosis. One factor underlying this is dyslipidemia, which in hyperinsulinemic subjects with... 
NONHUMAN-PRIMATES | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | TARGET GENES | ACTIVATION | PLASMA-CHOLESTEROL | DIABETIC DYSLIPIDEMIA | INSULIN-RESISTANCE | LIVER | TRANSPLANT RECIPIENTS | UP-REGULATION | Liver Transplantation | Insulin - physiology | Multiprotein Complexes | Serine Endopeptidases - physiology | Hepatocyte Nuclear Factor 4 - physiology | Mechanistic Target of Rapamycin Complex 1 | RNA Interference | Insulin Resistance - physiology | Receptor, Insulin - genetics | Serine Endopeptidases - genetics | Hyperinsulinism - genetics | Proprotein Convertases | Postoperative Complications | Hyperinsulinism - metabolism | Proteins - physiology | Receptors, LDL - genetics | Serine Endopeptidases - deficiency | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Proto-Oncogene Proteins c-akt - physiology | Receptor, Insulin - physiology | Receptor, Insulin - antagonists & inhibitors | Sirolimus - pharmacology | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Receptors, LDL - biosynthesis | Mice, Obese | Mice | TOR Serine-Threonine Kinases | Hepatocyte Nuclear Factor 1-alpha - physiology | Proteins - antagonists & inhibitors | Proprotein Convertase 9 | Measurement | Liver | Physiological aspects | Low density lipoprotein receptors | Cellular signal transduction | Research | Properties | Insulin | Health aspects
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 03/2004, Volume 113, Issue 5, pp. 764 - 773
  Accelerated atherosclerosis is a major cause of morbidity and death in insulin-resistant states such as obesity and the metabolic syndrome, but the... 
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2010, Volume 285, Issue 35, pp. 26861 - 26868
Journal Article
Circulation, ISSN 0009-7322, 10/2008, Volume 118, Issue 18, pp. 1837 - 1847
Background-Two macrophage ABC transporters, ABCA1 and ABCG1, have a major role in promoting cholesterol efflux from macrophages. Peritoneal macrophages... 
Lipoproteins | ABC transporters | Inflammation | Cholesterol | Atherosclerosis | atherosclerosis | CARDIAC & CARDIOVASCULAR SYSTEMS | INDUCED APOPTOSIS | CELLULAR CHOLESTEROL | NECROSIS-FACTOR-ALPHA | ABCG1(-/-) BONE-MARROW | HIGH-DENSITY-LIPOPROTEIN | APOLIPOPROTEIN-E | LIPID-ACCUMULATION | EFFLUX | inflammation | ABCA1-DEFICIENT MACROPHAGES | cholesterol | PERIPHERAL VASCULAR DISEASE | MICE | lipoproteins | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Lipoproteins - genetics | Membrane Microdomains - immunology | Signal Transduction - immunology | ATP-Binding Cassette Transporters - genetics | Mice, Mutant Strains | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Mice, Inbred DBA | ATP Binding Cassette Transporter 1 | Macrophages - immunology | Receptors, LDL - genetics | Atherosclerosis - immunology | Atherosclerosis - physiopathology | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Neutrophils - immunology | Receptors, LDL - metabolism | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Cholesterol - metabolism | Toll-Like Receptor 3 - metabolism | Toll-Like Receptor 4 - metabolism | Atherosclerosis - metabolism | Macrophages - metabolism | Animals | Lipopolysaccharides - pharmacology | Ligands | Macrophages - drug effects | Mice | ATP-Binding Cassette Transporters - immunology | Lipoproteins - immunology | Physiological aspects | Research | Macrophages | Gene expression | Toll-receptors
Journal Article
The Journal of Clinical Investigation, ISSN 0021-9738, 04/2009, Volume 119, Issue 4, pp. 1029 - 1041
Type 2 diabetes is associated with accelerated atherogenesis, which may result from a combination of factors, including dyslipidemia characterized by increased... 
Gene Expression | Apolipoproteins B/blood | Lipoproteins, VLDL/blood | Signal Transduction | Humans | Mice, Inbred C57BL | RNA, Small Interfering/genetics | Receptors, LDL/deficiency | Male | Mice, Transgenic | Glycogen Synthase Kinase 3/metabolism | Proto-Oncogene Proteins c-akt/genetics | Mice, Knockout | Animals | Receptor, Insulin/deficiency | Mice, Mutant Strains | Liver/metabolism | Insulin/metabolism | Mice, Obese | Mice | Lipids/blood | Atherosclerosis/blood | Lipogenesis | RECEPTOR-DEFICIENT MICE | MEDICINE, RESEARCH & EXPERIMENTAL | LIPID-METABOLISM | DIABETIC DYSLIPIDEMIA | LIPOPROTEIN SYNTHESIS | LDL RECEPTOR | TRANSCRIPTION FACTOR FOXO1 | FREE FATTY-ACIDS | APOLIPOPROTEIN-B SECRETION | RESISTANCE | ADIPOSE-TISSUE | RNA, Small Interfering - genetics | Apolipoproteins B - metabolism | Atherosclerosis - genetics | Receptor, Insulin - deficiency | Apolipoproteins B - blood | Proto-Oncogene Proteins c-akt - genetics | Atherosclerosis - etiology | Receptor, Insulin - genetics | Lipids - blood | Receptors, LDL - deficiency | Proto-Oncogene Proteins c-akt - metabolism | Receptors, LDL - genetics | Liver - metabolism | Glycogen Synthase Kinase 3 - metabolism | Atherosclerosis - metabolism | Atherosclerosis - blood | Insulin - metabolism | Lipoproteins, VLDL - blood | Lipoproteins, VLDL - metabolism | Receptor, Insulin - metabolism | Physiological aspects | Research | Insulin | Low density lipoproteins | Risk factors | Atherosclerosis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2006, Volume 103, Issue 9, pp. 3112 - 3117
Journal Article
Journal of Management in Engineering, ISSN 0742-597X, 11/2017, Volume 33, Issue 6, p. 5017005
AbstractThis study proposes a quantitative measurement method for the value of building information modeling (BIM) implementation during the construction phase... 
Case Studies | Quantitative measurement | Contract budget (CB) | BIM issue | Issue analysis | Building information modeling (BIM) value | ENGINEERING, CIVIL | ENGINEERING, INDUSTRIAL
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2009, Volume 119, Issue 4, pp. 886 - 898
ER stress occurs in macrophage-rich areas of advanced atherosclerotic lesions and contributes to macrophage apoptosis and subsequent plaque necrosis.... 
MEDICINE, RESEARCH & EXPERIMENTAL | KINASE INHIBITION | UNFOLDED PROTEIN RESPONSE | AKT ACTIVATION | ER STRESS | GENE-EXPRESSION | P38 MAPK | LOW-DENSITY LIPOPROTEIN | ENDOPLASMIC-RETICULUM STRESS | MOLECULAR-MECHANISMS | CELL-DEATH
Journal Article
Diabetes, ISSN 0012-1797, 11/2008, Volume 57, Issue 11, pp. 2967 - 2976
Forkhead Transcription Factors (FoxOs) Promote Apoptosis of Insulin-Resistant Macrophages During Cholesterol-Induced Endoplasmic Reticulum Stress Takafumi... 
ADVANCED ATHEROSCLEROTIC LESIONS | OXIDATIVE STRESS | ACTIVATION | PROTEIN | FACTOR FKHR | ENDOCRINOLOGY & METABOLISM | THERAPEUTIC IMPLICATIONS | RECEPTOR | SMOOTH-MUSCLE-CELLS | DEFICIENT MICE | NF-KAPPA-B | Apoptosis - drug effects | Endoplasmic Reticulum - metabolism | Forkhead Transcription Factors - physiology | Green Fluorescent Proteins - genetics | Macrophages, Peritoneal - cytology | Recombinant Fusion Proteins - metabolism | Transfection | Chromatin Immunoprecipitation | Forkhead Transcription Factors - metabolism | Receptor, Insulin - genetics | Adenoviridae - genetics | Stress, Physiological - drug effects | Macrophages, Peritoneal - drug effects | Green Fluorescent Proteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Receptor, Insulin - physiology | Forkhead Transcription Factors - genetics | Mice, Knockout | Animals | Transcription Factor RelA - metabolism | Fluorescent Antibody Technique | Insulin Resistance - genetics | Cholesterol - pharmacology | Recombinant Fusion Proteins - genetics | Forkhead Box Protein O1 | Mice | Apoptosis - physiology | Forkhead Box Protein O3 | Macrophages, Peritoneal - metabolism | Type 2 diabetes | Complications and side effects | Atherosclerosis | Genetic aspects | DNA binding proteins | Macrophages | Health aspects | Endoplasmic reticulum | Risk factors | Signal Transduction
Journal Article