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1. Full Text The effects of rasagiline on cognitive deficits in Parkinson's disease patients without dementia: A randomized, double-blind, placebo-controlled, multicenter study
: Letters: New Observations
by Hanagasi, Hasmet A
Movement Disorders, ISSN 0885-3185, 06/2015, Volume 30, Issue 7, pp. 1009 - 1009
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2. Full Text The effects of rasagiline on cognitive deficits in Parkinson's disease patients without dementia: A randomized, double‐blind, placebo‐controlled, multicenter study
by Hanagasi, Hasmet A
Movement Disorders, ISSN 0885-3185, 06/2015, Volume 30, Issue 7, pp. 1009 - 1009
CLINICAL NEUROLOGY | Neuroprotective Agents - therapeutic use | Parkinson Disease - complications | Double-Blind Method | Cognition Disorders - etiology | Humans | Parkinson Disease - drug therapy | Cognition Disorders - drug therapy | Indans - therapeutic use | Parkinson's disease | Pharmaceutical industry | Analysis | Dementia
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3. Full Text Dementia in Parkinson ' s d isease
by Hanagasi, Hasmet A and Tufekcioglu, Zeynep and Emre, Murat
Journal of the Neurological Sciences, ISSN 0022-510X, 2016
Abstract Dementia can occur in a substantial number of patients with Parkinson ' s disease with a point prevalence close to 30%. The cognitive profile is... 
Neurology
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4. Full Text Analysis of Mutations in AARS2 in a Series of CSF1R-Negative Patients With Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia
by Lynch, David S and Zhang, Wei Jia and Lakshmanan, Rahul and Kinsella, Justin A and Uzun, Günes Altiokka and Karbay, Merih and Tüfekçioglu, Zeynep and Hanagasi, Hasmet and Burke, Georgina and Foulds, Nicola and Hammans, Simon R and Bhattacharjee, Anupam and Wilson, Heather and Adams, Matthew and Walker, Mark and Nicoll, James A. R and Chataway, Jeremy and Fox, Nick and Davagnanam, Indran and Phadke, Rahul and Houlden, Henry
JAMA Neurology, ISSN 2168-6149, 12/2016, Volume 73, Issue 12, pp. 1433 - 1439
IMPORTANCE: Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a frequent cause of adult-onset leukodystrophy known to be... 
HEREDITARY DIFFUSE LEUKOENCEPHALOPATHY | CSF1R GENE | LEUKODYSTROPHY | INVOLVEMENT | BRAIN-STEM | SPECTRUM | CLINICAL NEUROLOGY | Leukoencephalopathies - genetics | Humans | Leukoencephalopathies - diagnostic imaging | Male | Leukoencephalopathies - physiopathology | Sequence Analysis, DNA | Exome | Young Adult | Magnetic Resonance Imaging | Alanine-tRNA Ligase - genetics | Pedigree | Adolescent | Microglia - pathology | Adult | Female | Mutation
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5. Full Text Dementia in Parkinson's disease
by Hanagasi, Hasmet A and Tufekcioglu, Zeynep and Emre, Murat
Journal of the Neurological Sciences, ISSN 0022-510X, 03/2017, Volume 374, pp. 26 - 31
Dementia can occur in a substantial number of patients with Parkinson's disease with a point prevalence close to 30%. The cognitive profile is characterized by... 
Parkinson's disease | Dementia with Lewy Bodies | Cholinesterase inhibitors | Dementia | RISK | ALPHA-SYNUCLEIN | MILD COGNITIVE IMPAIRMENT | MENTAL DYSFUNCTION | NEUROSCIENCES | CLINICAL NEUROLOGY | SOCIETY TASK-FORCE | COHORT | WHITE-MATTER HYPERINTENSITIES | SYDNEY MULTICENTER | DIAGNOSTIC-CRITERIA | LEWY BODIES | Parkinson Disease - complications | Dementia - pathology | Dementia - complications | Dementia - drug therapy | Humans | Parkinson Disease - epidemiology | Dementia - epidemiology | Cholinesterase Inhibitors - therapeutic use | Alzheimer's disease | Delusions | Delusional disorder
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6. Full Text Vitamin D Receptor Gene Haplotype Is Associated with Late-Onset Alzheimer's Disease
by Gezen-Ak, Duygu and Dursun, Erdinç and Bilgiç, Basar and Hanagasi, Hasmet and Ertan, Turan and Gürvit, Hakan and Emre, Murat and Eker, Engin and Ulutin, Turgut and Uysal, Ömer and Yilmazer, Selma
The Tohoku Journal of Experimental Medicine, ISSN 0040-8727, 2012, Volume 228, Issue 3, pp. 189 - 196
Vitamin D3 is a neurosteroid that mediates its effects via the vitamin D receptor (VDR). The VDR gene is located on chromosome 12q13 and consists of 9 exons.... 
neurodegeneration | vitamin D receptor | haplotype | Alzheimer's disease | vitamin D | Vitamin D | Neurodegeneration | Haplotype | Vitamin D receptor | MEDICINE, RESEARCH & EXPERIMENTAL | NERVOUS-SYSTEM | PERFORMANCE | D DEFICIENCY | RISK | POLYMORPHISM | PREVALENCE | MEDICINE, GENERAL & INTERNAL | 1,25-DIHYDROXYVITAMIN D-3 RECEPTORS | AMYLOID-BETA | BRAIN | Genetic Association Studies | Humans | Genotype | DNA Primers - genetics | Receptors, Calcitriol - genetics | Case-Control Studies | Haplotypes - genetics | Polymorphism, Restriction Fragment Length | Polymerase Chain Reaction | Aged, 80 and over | Polymorphism, Single Nucleotide - genetics | Aged | Alzheimer Disease - genetics
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7. Full Text A patient with early-onset Alzheimer's disease with a novel PSEN1 p.Leu424Pro mutation
by Guven, Gamze and Erginel-Unaltuna, Nihan and Samanci, Bedia and Gulec, Cagri and Hanagasi, Hasmet and Bilgic, Basar
Neurobiology of aging, ISSN 0197-4580, 06/2019
"Presenilin 1" (PSEN1) gene mutations are the major known genetic cause of early-onset Alzheimer's disease. Herein, we report a novel heterozygous PSEN1... 
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8. Full Text A new F‐box protein 7 gene mutation causing typical Parkinson's disease
by Lohmann, Ebba and Coquel, Anne‐Sophie and Honoré, Aurélie and Gurvit, Hakan and Hanagasi, Hasmet and Emre, Murat and Leutenegger, Anne L and Drouet, Valérie and Sahbatou, Mourad and Guven, Gamze and Erginel‐Unaltuna, Nihan and Deleuze, Jean‐Francois and Lesage, Suzanne and Brice, Alexis
Movement Disorders, ISSN 0885-3185, 07/2015, Volume 30, Issue 8, pp. 1130 - 1133
Background Recessive mutations in the F‐box protein 7 gene (FBXO7; PARK15) have been identified as a cause of the parkinsonian‐pyramidal syndrome. Here, we... 
phenotype | Parkinson disease | FBXO7 gene | Turkey | autosomal‐recessive | autosomal-recessive | WHITE-MATTER LESIONS | FBXO7 | CLINICAL NEUROLOGY | Pedigree | Humans | Middle Aged | Aged, 80 and over | Female | Male | Consanguinity | Mutation | Parkinson Disease - genetics | Parkinson Disease - physiopathology | F-Box Proteins - genetics | Sleep | Parkinson's disease | Gene mutations | Analysis | Genes | Depression, Mental | Genetic research | Genetic aspects | Nucleotide sequencing | DNA sequencing
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9. Full Text Association between selected cholesterol-related gene polymorphisms and Alzheimer’s disease in a Turkish cohort
by Guven, Gamze and Vurgun, Eren and Bilgic, Basar and Hanagasi, Hasmet and Gurvit, Hakan and Ozer, Ebru and Lohmann, Ebba and Erginel-Unaltuna, Nihan
Molecular Biology Reports, ISSN 0301-4851, 4/2019, Volume 46, Issue 2, pp. 1701 - 1707
Numerous genetic evidence has pointed out that variations in cholesterol-related genes may be associated with an Alzheimer’s disease (AD) risk. We aimed to... 
Life Sciences | Alzheimer’s disease | Animal Biochemistry | Risk | Animal Anatomy / Morphology / Histology | Cholesterol metabolism | Polymorphism | Linkage disequilibrium | Genes | Gene polymorphism | Cholesterol | Polymerase chain reaction | Genotype & phenotype | Genotyping | Apolipoprotein E | Alleles | Lipoprotein (low density) receptors | Alzheimer's disease | Age
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10. Full Text Using Exome Sequencing to Reveal Mutations in TREM2 Presenting as a Frontotemporal Dementia–like Syndrome Without Bone Involvement
by Guerreiro, Rita João and Lohmann, Ebba and Brás, José Miguel and Gibbs, Jesse Raphael and Rohrer, Jonathan D and Gurunlian, Nicole and Dursun, Burcu and Bilgic, Basar and Hanagasi, Hasmet and Gurvit, Hakan and Emre, Murat and Singleton, Andrew and Hardy, John
JAMA Neurology, ISSN 2168-6149, 01/2013, Volume 70, Issue 1, pp. 78 - 84
OBJECTIVE To identify new genes and risk factors associated with frontotemporal dementia (FTD). Several genes and loci have been associated with different... 
NASU-HAKOLA-DISEASE | COMPLEX | CYSTS | PARKINSON DISEASE | ALS | TAU | VPS35 | DIAGNOSTIC-CRITERIA | HEXANUCLEOTIDE REPEAT | C9ORF72 | CLINICAL NEUROLOGY | Frontotemporal Dementia - genetics | Frontotemporal Dementia - physiopathology | Exome - genetics | Humans | Risk Factors | Adult | Male | Mutation - genetics | Receptors, Immunologic - genetics | Syndrome | Frontotemporal Dementia - pathology | Membrane Glycoproteins - genetics
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11. Full Text Mutation frequency of the major frontotemporal dementia genes, MAPT, GRN and C9ORF72 in a Turkish cohort of dementia patients
by Guven, Gamze and Lohmann, Ebba and Bras, Jose and Gibbs, J. Raphael and Gurvit, Hakan and Bilgic, Basar and Hanagasi, Hasmet and Rizzu, Patrizia and Heutink, Peter and Emre, Murat and Erginel-Unaltuna, Nihan and Just, Walter and Hardy, John and Singleton, Andrew and Guerreiro, Rita
PLoS ONE, ISSN 1932-6203, 09/2016, Volume 11, Issue 9, p. e0162592
'Microtubule-associated protein tau' (MAPT), 'granulin' (GRN) and 'chromosome 9 open reading frame72' (C9ORF72) genemutations are the major known genetic... 
HEXANUCLEOTIDE REPEAT EXPANSION | DIAGNOSIS | LOBAR DEGENERATION | RECOMMENDATIONS | TAU-MUTATIONS | MULTIDISCIPLINARY SCIENCES | NULL MUTATIONS | GUIDELINES | DISEASE | PROGRANULIN | ASSOCIATION | Frontotemporal Dementia - genetics | Blotting, Southern | Progranulins | Humans | Intercellular Signaling Peptides and Proteins - genetics | Male | Exome | Proteins - genetics | Turkey | tau Proteins - genetics | Pedigree | Polymerase Chain Reaction | Female | C9orf72 Protein | Mutation | Cohort Studies | RNA | Gene mutations | Genes | Genetic aspects | Nucleotide sequencing | Protein binding | DNA sequencing | Neurosciences | Disease | Laboratories | Nervous system | Proteins | FUS protein | Clonal deletion | Neurodegeneration | Deletion | Dementia disorders | Aging | Genetics | Chromosomes | Deoxyribonucleic acid--DNA | Sequences | Amyotrophic lateral sclerosis | Ribonucleic acid--RNA | Patients | Medicine | Granulin | Neurology | RNA-binding protein | Brain research | Gene frequency | Chromosome 9 | Frontotemporal dementia | Dementia | Deoxyribonucleic acid | Ribonucleic acid | DNA
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12. Full Text Silent neurological involvement in biopsy-defined coeliac patients
by Bilgic, Basar and Aygun, Demet and Arslan, Ali Bilgin and Bayram, Ali and Akyuz, Filiz and Sencer, Serra and Hanagasi, Hasmet A
Neurological Sciences, ISSN 1590-1874, 12/2013, Volume 34, Issue 12, pp. 2199 - 2204
Coeliac disease (CD) is an autoimmune disease of small intestine associated with sensitivity to gluten. The clinical manifestations are often of... 
Neurology | Neurological involvement | White-matter | Medicine & Public Health | Cortical atrophy | Volumetry | Neurosurgery | Coeliac disease | Psychiatry | Neuroradiology | DIAGNOSIS | BRAIN ATROPHY | TRANSGLUTAMINASE | ABNORMALITIES | CEREBELLAR SYNDROME | NEUROSCIENCES | CLINICAL NEUROLOGY | GLUTEN ATAXIA | CHILDREN | WHITE-MATTER LESIONS | DISEASE | RATING-SCALE | Young Adult | Celiac Disease - pathology | Magnetic Resonance Imaging | Biopsy | Nerve Fibers, Myelinated - pathology | Humans | Middle Aged | Adolescent | Brain - pathology | Adult | Female | Male
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13. Full Text Peripheral GRN mRNA and Serum Progranulin Levels as a Potential Indicator for Both the Presence of Splice Site Mutations and Individuals at Risk for Frontotemporal Dementia
by Guven, Gamze and Bilgic, Başar and Tufekcioglu, Zeynep and Unaltuna, Nihan Erginel and Hanagasi, Hasmet and Gurvit, Hakan and Singleton, Andrew and Hardy, John and Emre, Murat and Gulec, Cagri and Bras, Jose and Guerreiro, Rita and Lohmann, Ebba
Journal of Alzheimer's Disease, ISSN 1387-2877, 2019, Volume 67, Issue 1, pp. 159 - 167
Progranulin (GRN) gene mutations are a major cause of frontotemporal dementia (FTD). Most mutations identified to date are null mutations, which are predicted... 
progranulin | frontotemporal dementia | serum | splice site mutation | ELISA | PLASMA | GENETIC-VARIABILITY | ALZHEIMER | CONTRIBUTES | CARRIERS | NEUROSCIENCES | FAMILY | Proteins | Dementia disorders | Biomarkers | Bioindicators | mRNA | Mutation | Frontotemporal dementia | Dementia | Haploinsufficiency
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14. Full Text Clinical variability in ataxia–telangiectasia
by Lohmann, Ebba and Krüger, Stefanie and Hauser, Ann-Kathrin and Hanagasi, Hasmet and Guven, Gamze and Erginel-Unaltuna, Nihan and Biskup, Saskia and Gasser, Thomas
Journal of Neurology, ISSN 0340-5354, 7/2015, Volume 262, Issue 7, pp. 1724 - 1727
Ataxia–telangiectasia (A-T) is an autosomal recessive inherited disease characterized by progressive childhood-onset cerebellar ataxia, oculomotor apraxia,... 
Neurology | Neurosciences | Phenotype | Turkey | Medicine & Public Health | ATM | Dystonia | Neuroradiology | CLINICAL NEUROLOGY | Exome - genetics | Base Sequence | Humans | Middle Aged | Adult | Ataxia Telangiectasia - genetics | Family Health | Female | Male | Ataxia Telangiectasia Mutated Proteins - genetics | Mutation - genetics | Complications and side effects | Patient outcomes | Ataxia telangiectasia | Development and progression | Research | Risk factors
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15. Full Text Prevalence of Parkinson's disease in Baskale, Turkey: a population based study
by Durmus, H and Gokalp, MA and Hanagasi, HA
NEUROLOGICAL SCIENCES, ISSN 1590-1874, 03/2015, Volume 36, Issue 3, pp. 411 - 413
Parkinson's disease (PD) is the second most common neurodegenerative disease, and its prevalence rate varies between 15 and 250/100.000. The data on the... 
Population based | Parkinson's disease | Prevalence | Turkey | RISK | NEUROSCIENCES | CLINICAL NEUROLOGY | Rural Population - statistics & numerical data | Turkey - epidemiology | Humans | Middle Aged | Aged, 80 and over | Parkinson Disease - epidemiology | Female | Male | Aged | Medicine, Experimental | Medical research | Prevalence studies (Epidemiology)
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16. Full Text SPORADIC FATAL INSOMNIA IN A YOUNG TURKISH MAN
by Yildirim, Zerrin and Tufekcioglu, Zeynep and Tatlidede, Asli Demirtas and Bilgiç, Başar and Hanagasi, Hasmet A and Gurvit, Hakan I
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P1468 - P1469
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17. Full Text CATATONIA AS CLINICAL PRESENTATION OF ANTI-N-METHYL-D-ASPARTATE (ANTI-NMDA) RECEPTOR ENCEPHALITIS
by Hanagasi, Hasmet A and Sezgin, Mine and Bilgiç, Başar and Seçkin, Merve and Tufekcioglu, Zeynep and Gurvit, Hakan I and Emre, Murat
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P1467 - P1468
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18. Full Text Olfactory function and olfactory bulb volume in Wilson’s disease
by Degirmenci, Nazan and Degirmenci, Nazan and Veyseller, Bayram and Veyseller, Bayram and Hanagasi, Hasmet and Hanagasi, Hasmet and Bilgic, Basar and Bilgic, Basar and Gurbuz, Defne and Gurbuz, Defne and Toprak, Ali and Toprak, Ali and Ozturan, Orhan and Ozturan, Orhan
European Archives of Oto-Rhino-Laryngology, ISSN 0937-4477, 1/2019, Volume 276, Issue 1, pp. 139 - 142
To evaluate the olfactory function and the olfactory bulb (OB) volume changes in Wilson’s Disease (WD) patients.A prospective, controlled, single-blinded study... 
Wilson’s disease | Olfactory dysfunction | Medicine & Public Health | Head and Neck Surgery | Olfaction | Olfactory bulb | Otorhinolaryngology | Neurosurgery
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19. Full Text Pain is common in Parkinson's disease
by Hanagasi, Hasmet A and Akat, Sinem and Gurvit, Hakan and Yazici, Jale and Emre, Murat
Clinical Neurology and Neurosurgery, ISSN 0303-8467, 2010, Volume 113, Issue 1, pp. 11 - 13
Abstarct Objective and background Patients with Parkinson's disease may present with severe or intractable pain, which can be more distressing than the motor... 
Neurology | Neurosurgery | Non-motor symptoms | Pain | Parkinson's disease | SURGERY | DIAGNOSIS | LEEDS ASSESSMENT | NEUROPATHIC SYMPTOMS | SCALE | CLINICAL NEUROLOGY | Parkinson Disease - complications | Prospective Studies | Pain - epidemiology | Levodopa - therapeutic use | Humans | Middle Aged | Anxiety - psychology | Male | Parkinson Disease - psychology | Antiparkinson Agents - therapeutic use | Pain - psychology | Psychiatric Status Rating Scales | Aged, 80 and over | Anxiety - complications | Depression - psychology | Pain - etiology | Adult | Depression - complications | Female | Aged | Pain Measurement
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20. Full Text Cognitive and anatomical correlates of anosognosia in amnestic mild cognitive impairment and early-stage Alzheimer's disease
by Senturk, Gulben and Bilgic, Basar and Arslan, Ali Bilgin and Bayram, Ali and Hanagasi, Hasmet and Gurvit, Hakan and Emre, Murat
International Psychogeriatrics, ISSN 1041-6102, 02/2017, Volume 29, Issue 2, pp. 293 - 302
Background: Anosognosia is a common feature in Alzheimer's disease (AD). The brain substrates of anosognosia are not fully understood, and less is known about... 
Alzheimer's disease | mild cognitive impairment | DEPRESSION | DEMENTIA | PSYCHIATRY | MEMORY DEFICITS | AWARENESS | PSYCHOLOGY, CLINICAL | PSYCHIATRIC-SYMPTOMS | PSYCHOLOGY | GERIATRICS & GERONTOLOGY | UNAWARENESS | FREQUENCY | SELF-APPRAISAL | GERONTOLOGY | ASSOCIATION | Agnosia - psychology | Alzheimer Disease - complications | Humans | Middle Aged | Cerebral Cortex - pathology | Memory, Episodic | Organ Size | Male | Cognition | Cerebral Cortex - diagnostic imaging | Neuropsychological Tests | Magnetic Resonance Imaging | Psychiatric Status Rating Scales | Turkey | Aged, 80 and over | Cognitive Dysfunction - psychology | Female | Aged | Cognitive Dysfunction - complications | Executive Function | Alzheimer Disease - psychology | Nuclear magnetic resonance--NMR | Alzheimers disease | Memory | Questionnaires | Cognitive ability
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