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1. Hepatitis delta virus
by Handa, H and Yamaguchi, Yuki
2006, 1. Aufl., Medical intelligence unit., ISBN 9780387322308, vii, 94
Currently not available, will follow before Dec 30. 
Delta-associated agent | Delta infection | Other branches of medicine | Medical Microbiology | Molecular Medicine | Biomedicine | Virology
Book
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2. Full Text Angina and Future Cardiovascular Events in Stable Patients With Coronary Artery Disease: Insights From the Reduction of Atherothrombosis for Continued Health (REACH) Registry
by Eisen, Alon and Bhatt, Deepak L and Steg, P. Gabriel and Eagle, Kim A and Goto, Shinya and Guo, Jianping and Smith, Sidney C and Ohman, E. Magnus and Scirica, Benjamin M and REACH Registry Investigators and the REACH Registry Investigators
Journal of the American Heart Association, ISSN 2047-9980, 10/2016, Volume 5, Issue 10, p. n/a
Background-The extent to which angina is associated with future cardiovascular events in patients with coronary artery disease has long been debated. Methods... 
cardiovascular events | coronary artery disease | angina | Cardiovascular events | Coronary artery disease | Angina | CARDIAC & CARDIOVASCULAR SYSTEMS | OUTPATIENTS | MYOCARDIAL-ISCHEMIA | RISK | SYMPTOMS | RATES | HEART-DISEASE | SOUL | PECTORIS | CLARIFY REGISTRY | CLINICAL-OUTCOMES | United States - epidemiology | Myocardial Infarction - epidemiology | Prognosis | Humans | Middle Aged | Proportional Hazards Models | Hospitalization - statistics & numerical data | Male | Case-Control Studies | Myocardial Revascularization - utilization | Angina, Stable - epidemiology | Cardiovascular Diseases - mortality | Female | Registries | Stroke - epidemiology | Aged | Coronary Artery Disease - epidemiology | Odds Ratio | Heart Failure - epidemiology | Index Medicus
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3. Full Text 29th World Congress of Endourology & SWL WCE 2011 Scientific Program & Abstracts
by Chris J, Allender and Jenna L, Bowen and Widatella, Awadalla and Iason, Kyriazis and Nikolaos, Tsopanoglou and Panagiotis, Kallidonis and Odysseas, Andrikopoulos and Despoina, Liourdi and Helen, Papadaki and Konstantina, Geronatsiou and Nicolas, Haseke and Sebastian, Walther and Christan, Gratzke and Christain G, Stief and Ronald, Sroka and Ephrem O, Olweny and Stephen, Faddegon and Stacey, McLeroy and Raul, Fernandez and Bruce E, Gnade and Heather E, Beardsley and Margaret S, Pearle and Jeffrey A, Cadeddu and Jeffrey A, Cadeddu and Tatsuo, Igarashi and Takuro, Ishii and Satoki, Zenbutsu and Yukio, Naya and Nuzhath, Khan and Deirdre, Anderson and Jonathan, Watkiss and Ben, Challacombe and Mohammed Shamim, Khan and Prokar, Dasgupta and Declan, Cahill and Nuzhath, Khan and Deirdre, Anderson and Faria, Khan and Jonathan, Watkiss and Ben, Challacombe and Mohammed Shamim, Khan and Prokar, Dasgupta and Declan, Cahill and Nieroshan, Rajarubendra and Ping Han, Chia and Aasheen, Munshey and Shomik, Sengupta and Damien, Bolton and Oneel, Patel and Lin, Xiao and Joseph, Ischia and Graham, Baldwin and Arthur, Schulkes and Payal, Kapur and Yung K, Tan and Samuel K, Park and Mehrad, Adibi and Sara L, Best and Jeffrey A, Cadeddu and Daniel M, de Bruin and Dirk J, Faber and Ton G, van Leeuwen and Jean J, de la Rosette and Pilar, Laguna and Shubha, De and Leah, Grossman and Niels, Johnsen and Greg, Mitchell and Ted, Klein and Benjamin, Lee and Panagiotis, Kitrou and Dimitrios, Karnabatidis and Christina, Kalogeropoulou and Athanasios, Tsamandas and Theofanis, Vrettos and Ioannis, Georgiopoulos and Aarond D, Benson and Bradley F, Schwartz and Kristina L, Penniston and Lauren, Iwicki and Ibrahim, Saeed and Thomas D, Crenshaw and Stephen Y, Nakada and Vivek, Joshi and Sushil, Karia and Sudhir, Sheth and Jitendra, Amlani and Sunil, Moteria and Mohammad Reza, Darabi mahboub and Eugene, Fuchs and Michael, Conlin and Hassan, Razvi and John D, Denstedt and Linda, Nott and Ad, Hendrikx and Michael, Luke and S.K, Pal and Jean, de la Rosette and Sunil, M and Maria Chiara, Sighinolfi and ...
Journal of Endourology, ISSN 0892-7790, 11/2011, Volume 25, Issue S1, pp. P1 - A373
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4. Real-time analysis of biomolecular interactions
: applications of BIACORE
by Handa, H. 1946- (Hiroshi) and Nagata, Kazuhiro, 1947
2000, ISBN 9784431702894, x, 256
Physical biochemistry | Biomolecules | Chemical kinetics
Book
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5. Full Text Looking for Niche Research
: From Telomerase to Non-coding RNA
by Handa, Hiroshi
The Kitakanto Medical Journal, ISSN 1343-2826, 05/2019, Volume 69, Issue 2, pp. 159 - 160
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6. Full Text Identification of a Primary Target of Thalidomide Teratogenicity
by Takumi Ito and Hideki Ando and Yoshimasa Imamura and Yuki Yamaguchi and Hiroshi Handa and Takayuki Suzuki and Toshihiko Ogura and Kentaro Hotta
Science, ISSN 0036-8075, 3/2010, Volume 327, Issue 5971, pp. 1345 - 1350
Half a century ago, thalidomide was widely prescribed to pregnant women as a sedative but was found to be teratogenic, causing multiple birth defects. Today,... 
Receptors | Messenger RNA | Delta cells | Ubiquitins | Substrate specificity | Teratogenicity | HeLa cells | Pectorals | Cellular immunity | Embryos | Research Article | MULTIPLE-MYELOMA | CELLS | LIMB DEFECTS | ORIGIN | ZEBRAFISH | UBIQUITIN LIGASE | PATHWAY | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | OUTGROWTH | EXPRESSION | Teratogens - toxicity | Thalidomide - metabolism | Peptide Hydrolases - genetics | Forelimb - embryology | Humans | Fibroblast Growth Factors - genetics | Ubiquitin-Protein Ligases - antagonists & inhibitors | Zebrafish - embryology | Embryo, Nonmammalian - drug effects | DNA-Binding Proteins - metabolism | Fibroblast Growth Factors - metabolism | Ubiquitination | Forelimb - abnormalities | Gene Expression Regulation, Developmental | Cullin Proteins - metabolism | Peptide Hydrolases - metabolism | Zebrafish Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Mutant Proteins - metabolism | Chick Embryo | Thalidomide - toxicity | Zebrafish - genetics | Animals | Carrier Proteins - metabolism | HeLa Cells | Zebrafish Proteins - genetics | Embryonic Development - drug effects | Teratogens - metabolism | Dosage and administration | Research | Teratogenic agents | Thalidomide | Protein binding | Pharmacology | Birth defects | Developmental biology | DNA damage | Binding sites | Index Medicus
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7. Sōgō enshū wāku nōto
: atarashii jidai no gakushūron "sōgō enshū" e no michishirube
by Okuyama, Akihiro, 1933 and Handa, Hiroshi, 1935
2000, ISBN 4924339768, 262
Teachers | Training of
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8. Full Text Correction to: Thalidomide maintenance therapy in Japanese myeloma patients: a multicenter, phase II clinical trial (COMET study)
by Murakami, Hirokazu and Kasamatsu, Tetsuhiro and Murakami, Jun and Kiguchi, Toru and Kanematsu, Takeshi and Ogawa, Daisuke and Takamatsu, Hiroyuki and Handa, Hiroshi and Ozaki, Shuji and Miki, Hirokazu and Takahashi, Takeshi and Takeo, Takaaki and Yamauchi, Tatsuya and Morishita, Takanobu and Kosugi, Hiroshi and Shimizu, Kazuyuki
International Journal of Hematology, ISSN 0925-5710, 7/2019, Volume 110, Issue 1, pp. 125 - 126
The authors would like to correct the errors in the publication of the original article. The correction details are given below. 
Medicine & Public Health | Hematology | Oncology | Medicine, Experimental | Medical research | Product development | Thalidomide | Clinical trials | Myeloma
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9. Full Text Multiple Myeloma: from Diagnosis to the Up-to-date Treatment. Topics: I. Epidemiology and Prognostic Change of Multiple Myeloma
by Handa, Hiroshi
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, ISSN 0021-5384, 07/2016, Volume 105, Issue 7, pp. 1202 - 1208
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10. Full Text Multiple Myeloma: from Diagnosis to the Up-to-date Treatment. Topics: I. Epidemiology and Prognostic Change of Multiple Myeloma
by Handa, Hiroshi
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, ISSN 0021-5384, 07/2016, Volume 105, Issue 7, pp. 1202 - 1208
Multiple Myeloma - epidemiology | Age Distribution | Prognosis | Multiple Myeloma - diagnosis | Humans | Middle Aged | Child, Preschool | Infant | Male | Young Adult | Adolescent | Aged, 80 and over | Adult | Female | Aged | Child | Infant, Newborn | Cohort Studies | Index Medicus
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11. Full Text Signs of biological activities of 28,000-year-old mammoth nuclei in mouse oocytes visualized by live-cell imaging
by Yamagata, Kazuo and Nagai, Kouhei and Miyamoto, Hiroshi and Anzai, Masayuki and Kato, Hiromi and Miyamoto, Kei and Kurosaka, Satoshi and Azuma, Rika and Kolodeznikov, Igor I and Protopopov, Albert V and Plotnikov, Valerii V and Kobayashi, Hisato and Kawahara-Miki, Ryouka and Kono, Tomohiro and Uchida, Masao and Shibata, Yasuyuki and Handa, Tetsuya and Kimura, Hiroshi and Hosoi, Yoshihiko and Mitani, Tasuku and Matsumoto, Kazuya and Iritani, Akira
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 4050 - 12
The 28,000-year-old remains of a woolly mammoth, named 'Yuka', were found in Siberian permafrost. Here we recovered the less-damaged nucleus-like structures... 
LONG-TERM | READ ALIGNMENT | GENOME SEQUENCE | MULTIDISCIPLINARY SCIENCES | DEAMIDATION | REVEAL | WOOLLY MAMMOTH | Nuclear transfer | Permafrost | Nuclei | DNA damage | Oocytes
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12. Full Text Exhaled breath analysis for lung cancer detection using ion mobility spectrometry
by Ha, Hiroshi and Usuba, Ayano and Maddula, Sasidhar and Baumbach, Jörg Ingo and Mineshita, Masamichi and Miyazawa, Teruomi
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, pp. e114555 - e114555
Background: Conventional methods for lung cancer detection including computed tomography (CT) and bronchoscopy are expensive and invasive. Thus, there is still... 
BIOMARKERS | CONDENSATE | DIAGNOSIS | PROFILES | ARRAY | MULTIDISCIPLINARY SCIENCES | AIR | CANINE SCENT DETECTION | MUTATIONS | VOLATILE ORGANIC-COMPOUNDS | Lung Neoplasms - genetics | Receptor, Epidermal Growth Factor - genetics | Alkanes - analysis | Humans | Middle Aged | Volatile Organic Compounds - analysis | Male | Adenocarcinoma - diagnosis | Spectrum Analysis - methods | Adult | Female | Adenocarcinoma - genetics | Aged | Decision Trees | Mutation | Lung Neoplasms - diagnosis | Breath Tests - methods | Smoking | Volatile organic compounds | Squamous cell carcinoma | Algorithms | Lung cancer | Spectrum analysis | Diagnosis | Cancer | Adenocarcinoma | Bronchoscopy | Spectroscopy | Dodecane | Epidermal growth factor receptors | Invasiveness | Lung | Ionic mobility | Mobility | Patients | Spectrometry | Sensitivity | Epidermal growth factor | Computed tomography | Biopsy | Volatile organic compounds--VOCs | Organic compounds | Index Medicus | VOCs
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13. Full Text Systematic changes to the apparent diffusion tensor of in vivo rat brain measured with an oscillating-gradient spin-echo sequence
by Kershaw, Jeff and Leuze, Christoph and Aoki, Ichio and Obata, Takayuki and Kanno, Iwao and Ito, Hiroshi and Yamaguchi, Yuki and Handa, Hiroshi
NeuroImage, ISSN 1053-8119, 04/2013, Volume 70, pp. 10 - 20
As the oscillating gradient spin-echo sequence has shown promise as a means to probe tissue microstructure, it was applied here to diffusion-tensor imaging of... 
Restricted diffusion | In vivo rat brain | Oscillating-gradient spin-echo | Apparent diffusion tensor | Tissue microstructure | Effective diffusion-time | WHITE-MATTER | NEUROSCIENCES | NEUROIMAGING | TIME-DEPENDENT DIFFUSION | NMR | WATER DIFFUSION | COEFFICIENT | SPECTROSCOPY | LARGE B-VALUES | POROUS-MEDIA | PROBE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Diffusion Tensor Imaging - methods | Animals | Brain - anatomy & histology | Anisotropy | Rats | Male | Brain - physiology | Rats, Sprague-Dawley | Brain | Studies | Hypotheses | Brain research | Diffusion | Experiments | Rodents | Index Medicus
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14. Full Text I. Epidemiology and Prognostic Change of Multiple Myeloma
by Handa, Hiroshi
Nihon Naika Gakkai Zasshi, ISSN 0021-5384, 2016, Volume 105, Issue 7, pp. 1202 - 1208
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15. Full Text Another action of a thalidomide derivative
by Ito, Takumi and Handa, Hiroshi
Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7559, pp. 167 - 168
As well as being effective against myeloma, lenalidomide can treat2 a type of myelodysplastic syndrome (MDS) - a disorder of blood stem cells (haematopoietic... 
Dosage and administration | Thalidomide | Identification and classification | Drug interactions | Drugs | Proteins | Enzymes | Ligands | Mutation | Kinases | Blood diseases | Chromosomes | Apoptosis
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16. Aberrant micro RNA and epigenetic network are associated with progression from MGUS to multiple myeloma
by Handa, Hiroshi
[Rinshō ketsueki] The Japanese journal of clinical hematology, ISSN 0485-1439, 08/2015, Volume 56, Issue 8, pp. 981 - 988
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17. Aberrant micro RNA and epigenetic network are associated with progression from MGUS to multiple myeloma
by Handa, Hiroshi
[Rinsho ketsueki] The Japanese journal of clinical hematology, ISSN 0485-1439, 08/2015, Volume 56, Issue 8, p. 981
In recent years, attention has been drawn to aberrant epigenetics as well as coding gene mutations in cancers. DNA methylation, histone acetylation and... 
Multiple Myeloma - pathology | Monoclonal Gammopathy of Undetermined Significance - genetics | Monoclonal Gammopathy of Undetermined Significance - pathology | Cell Transformation, Neoplastic | Epigenesis, Genetic | Humans | Gene Expression Regulation, Neoplastic | Chromosomes, Human | MicroRNAs - genetics | Mutation | Disease Progression | Multiple Myeloma - genetics
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18. Full Text Identification of Dendrobium Species Used for Herbal Medicines Based on Ribosomal DNA Internal Transcribed Spacer Sequence
by Takamiya, Tomoko and Wongsawad, Pheravut and Tajima, Natsuko and Shioda, Nao and Lu, Jun Feng and Wen, Chi Luan and Wu, Jin Bin and Handa, Takashi and Iijima, Hiroshi and Kitanaka, Susumu and Yukawa, Tomohisa
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2011, Volume 34, Issue 5, pp. 779 - 782
Stems of genus Dendrobium (Orchidaceae) have been traditionally used as an herbal medicine (Dendrobii Herba) in Eastern Asia. Although demand for Dendrobium is... 
Orchidaceae | molecular identification | herbal medicine | Dendrobium | ribosomal DNA | internal transcribed spacer | Herbal medicine | Internal transcribed spacer | Molecular identification | Ribosomal DNA | MIGO | PHYLOGENY | MARKERS | OFFICINALE KIMURA | NOBILE | AUTHENTICATION | PHARMACOLOGY & PHARMACY | INSIGHTS | DNA, Ribosomal - drug effects | DNA Primers | Base Sequence | Herbal Medicine | Polymerase Chain Reaction | Dendrobium - chemistry | Index Medicus
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19. Full Text Thalidomide maintenance therapy in Japanese myeloma patients: a multicenter, phase II clinical trial (COMET study)
by Murakami, Hirokazu and Kasamatsu, Tetsuhiro and Murakami, Jun and Kiguchi, Toru and Kanematsu, Takeshi and Ogawa, Daisuke and Takamatsu, Hiroyuki and Handa, Hiroshi and Ozaki, Shuji and Miki, Hirokazu and Takahashi, Takeshi and Takeo, Takaaki and Yamauchi, Tatsuya and Morishita, Takanobu and Kosugi, Hiroshi and Shimizu, Kazuyuki
International Journal of Hematology, ISSN 0925-5710, 4/2019, Volume 109, Issue 4, pp. 409 - 417
A prospective, multicenter, phase II study was performed to assess the efficacy and safety of thalidomide maintenance therapy at different doses in Japanese... 
Medicine & Public Health | Hematology | Adverse events | Multiple myeloma | Oncology | Efficacy | Maintenance | Thalidomide | DIAGNOSED MULTIPLE-MYELOMA | SURVIVAL | DEXAMETHASONE | SINGLE | PREDNISONE | CONSOLIDATION THERAPY | LENALIDOMIDE | STEM-CELL TRANSPLANTATION | HEMATOLOGY | ELDERLY-PATIENTS | MELPHALAN | Thalidomide - adverse effects | Disease-Free Survival | Asian Continental Ancestry Group | Multiple Myeloma - drug therapy | Prospective Studies | Multiple Myeloma - mortality | Humans | Japan | Survival Rate | Maintenance Chemotherapy | Thalidomide - administration & dosage | Medicine, Experimental | Clinical trials | Medical research | Product development | Therapy | Patients | Index Medicus
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20. Science is one's originality and pride
by Handa, Hiroshi
Journal of Tokyo Medical University, ISSN 0040-8905, 07/2015, Volume 73, Issue 3, pp. 219 - 220
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