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Methods in Enzymology, ISSN 0076-6879, 2016, Volume 570, pp. xxi - xxii
Journal Article
Trends in Immunology, ISSN 1471-4906, 06/2019, Volume 40, Issue 6, pp. 472 - 481
Recruitment of immune cells from the vasculature relies on the presentation of glycosaminoglycan-bound chemokines on the luminal side of vascular endothelial... 
glycocalyx | glycosaminoglycans | receptors | chemokines | Immunoglobulins | Glycosaminoglycans | Leukocytes | Grants | Endothelial cells | Cell adhesion & migration | Endothelium | White blood cells | Receptors | Ligands | Chemokines | Binding sites | Anomalies | Immune system
Journal Article
Cytokine, ISSN 1043-4666, 09/2018, Volume 109, pp. 1 - 1
Journal Article
Trends in Pharmacological Sciences, ISSN 0165-6147, 06/2018, Volume 39, Issue 6, pp. 547 - 559
Recent crystal structures of multiple G protein-coupled receptors (GPCRs) have revealed a highly conserved intracellular pocket that can be used to modulate... 
G protein-coupled receptors | intracellular binding site | antagonism | small molecules | allosteric modulation | ACTIVATION | C-TERMINUS | PROTEIN-COUPLED RECEPTOR | SMALL-MOLECULE | CRYSTAL-STRUCTURE | PHARMACOLOGY & PHARMACY | ALLOSTERIC MODULATION | CHEMOKINE RECEPTORS | AGONIST PEPDUCIN | IDENTIFICATION | ANTAGONIST BINDING-SITE | Protein binding
Journal Article
2016, First edition., Methods in Enzymology, ISBN 0128021713, Volume 570
Web Resource
03/2016, Methods in enzymology, ISBN 9780128021712, Volume 570, 676
Chemokines, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the... 
Chemokines
eBook
SCIENCE SIGNALING, ISSN 1945-0877, 09/2019, Volume 12, Issue 598, p. eaaw3657
Chemokines bind to membrane-spanning chemokine receptors, which signal through G proteins and promote cell migration. However, atypical chemokine receptor 3... 
ACTIVATION | FUNCTIONAL-ACTIVITY | INHIBITION | RECOGNITION | SMALL-MOLECULE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TYROSINE SULFATION | CXCR4 | GPCR | G-PROTEIN | EFFICIENT | CELL BIOLOGY
Journal Article
Methods in cell biology, ISSN 0091-679X, 2019, Volume 149, p. 259
The past decade has witnessed remarkable progress in the determination of G protein-coupled receptor (GPCR) structures, profoundly expanding our understanding... 
Cell Line | Animals | Magnetic Resonance Spectroscopy - methods | Receptors, G-Protein-Coupled - metabolism | Solutions | Receptors, CXCR - metabolism | Humans | Staining and Labeling | Carbon Isotopes - chemistry | Vitamin U - metabolism
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 08/2016, Volume 113, Issue 35, pp. 9928 - 9928
The atomic-level mechanisms by which G protein-coupled receptors (GPCRs) transmit extracellular ligand binding events through their transmembrane helices to... 
Journal Article
2009, 1st ed., Methods in enzymology, ISBN 9780123749086, Volume 460-461., 2 v.
The understanding of chemokines, the proteins that control the migration of cells, and their receptors, is critical to the study of causes and therapies for a... 
Chemokines
Book
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 12/2014, Volume 111, Issue 50, pp. E5363 - E5363
Chemokines and their receptors regulate cell migration during development, immune system function, and in inflammatory diseases, making them important... 
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 06/2017, Volume 46, Issue 6, pp. 1005 - 1017.e5
CCR5 is the primary chemokine receptor utilized by HIV to infect leukocytes, whereas CCR5 ligands inhibit infection by blocking CCR5 engagement with HIV gp120.... 
maraviroc | V3 loop | CCL5/RANTES | G protein-coupled receptor (GPCR) | Chemokine antagonist | CCR5-gp120 interaction | viral mimicry | membrane protein structure | two-site model | HIV entry inhibitor | CCR5 Receptor Antagonists - chemistry | CCR5 Receptor Antagonists - pharmacology | Triazoles - chemistry | Cyclohexanes - pharmacology | HIV Fusion Inhibitors - chemistry | Humans | Crystallography, X-Ray | Structure-Activity Relationship | Virus Internalization - drug effects | HIV Envelope Protein gp120 - metabolism | Spodoptera | Chemokine CCL5 - chemistry | HIV Infections - immunology | Molecular Mimicry | Receptors, CCR5 - metabolism | Sf9 Cells | HIV-1 - physiology | Cloning, Molecular | Cyclohexanes - chemistry | Chemokine CCL5 - metabolism | HIV Envelope Protein gp120 - chemistry | Models, Molecular | Triazoles - pharmacology | Animals | Protein Binding | Receptors, CCR5 - chemistry | HIV Infections - drug therapy | Protein Conformation | Hydrogen | Analysis | Pharmacy | Therapeutics | Drugstores | HIV (Viruses) | Drug approval | Homeopathy | Materia medica and therapeutics | G proteins | Membrane proteins | Similarity | Molecular structure | Infections | Leukocytes | Hydrogen bonding | Mimicry | Exploitation | Proteins | Hydrogen bonds | Design improvements | Human immunodeficiency virus--HIV | Plasticity | Chemical bonds | Modelling | Binding | CCR5 protein | Diseases | Molecular modelling | Inhibitors | Ligands | Determinants | Plastic properties | Molecular biology | Chemokines | Glycoprotein gp120 | Recognition | Cancer | BASIC BIOLOGICAL SCIENCES | 60 APPLIED LIFE SCIENCES | RANTES | CCL5
Journal Article