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Frontiers in Microbiology, ISSN 1664-302X, 03/2018, Volume 9, p. 415
Journal Article
ISSN 1463-9076, 6/2019, Volume 21, Issue 23, pp. 1253 - 12539
The emergence of antibiotic-resistance is a major concern to global human health and identification of novel antibiotics is critical to mitigate the threat.... 
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 07/2019, Volume 374, pp. 32 - 40
associated disease (CDAD) is the leading infectious cause of antibiotic-associated diarrhea and colitis in the United States. Both the incidence and severity... 
OG253 | Mutacin | Bacteriocin | Lantibiotic | CDAD | Lanthipeptide | Nisin and Toxicokinetics
Journal Article
Physical Chemistry Chemical Physics : PCCP, ISSN 1463-9076, 01/2019, Volume 21, Issue 23, pp. 12530 - 12539
The emergence of antibiotic-resistance is a major concern to global human health and identification of novel antibiotics is critical to mitigate the threat.... 
Binding | Nisin | Water chemistry | Peptides | Gram-positive bacteria | Chains | Lipids | Antiinfectives and antibacterials | Antibiotics | Bacteria | Disruption | Porosity | Relocation | Pore formation
Journal Article
Pediatric Research, ISSN 0031-3998, 05/2009, Volume 65, Issue 5, pp. 91R - 97R
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 04/2019, Volume 63, Issue 4
Lantibiotics present an attractive scaffold for the development of novel antibiotics. We report here a novel lantibiotic for the treatment of Clostridium... 
Nisin | Antibiotic | Mutacin | Mutagenesis | Antibiotic resistance | Bacteriocin | Lantibiotic | Bioavailability | Lanthipeptide | Antimicrobial peptide | antibiotic | DRUG | TARGET | nisin | PREVENTION | MICROBIOLOGY | lanthipeptide | mutacin | mutagenesis | lantibiotic | IN-VITRO | antibiotic resistance | bioavailability | LIPID-II | PHARMACOLOGY & PHARMACY | antimicrobial peptide | bacteriocin | Index Medicus
Journal Article
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, ISSN 1463-9076, 06/2019, Volume 21, Issue 23, pp. 12530 - 12539
The emergence of antibiotic-resistance is a major concern to global human health and identification of novel antibiotics is critical to mitigate the threat.... 
NISIN | TARGET | LIPID-II | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | RESISTANCE | DYNAMICS | CHEMISTRY, PHYSICAL | CONDUCTION | CELL-WALL PRECURSOR | SIMULATIONS | BINDING | SINGLE-FILE WATER
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 7, p. e11714
The cytolethal distending toxin (CDT) of the oral pathogen Aggregatibacter actinomycetemcomitans induces cell cycle arrest and apoptosis in various cell types.... 
ACTINOBACILLUS-ACTINOMYCETEMCOMITANS | G ARREST | PROTEIN | INHIBITION | CYTOLETHAL DISTENDING TOXIN | PHOSPHORYLATION | DNA-DAMAGE | BIOLOGY | CYCLE ARREST | FIBROBLASTS | HUMAN T-CELLS | Caspase 9 - genetics | Caspase 9 - metabolism | Epithelial Cells - metabolism | Apoptosis - drug effects | Epithelial Cells - drug effects | Humans | Caspase 3 - metabolism | Apoptosis - genetics | DNA-Binding Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | DNA Breaks, Double-Stranded - drug effects | Tumor Suppressor Proteins - genetics | Caspase 3 - genetics | Cell Cycle Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Epithelial Cells - cytology | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Tumor Suppressor Proteins - metabolism | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Signal Transduction - genetics | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Aggregatibacter actinomycetemcomitans - chemistry | Blotting, Western | Signal Transduction - drug effects | Bacterial Toxins - pharmacology | Gingiva - cytology | Checkpoint Kinase 2 | RNA, Small Interfering | Infection | Cellular signal transduction | Health aspects | Protein kinases | Analysis | Apoptosis | Protein kinase C | Phosphorylation | Epithelial cells | DNA damage | Biology | Kinases | Phosphatase | Caspase-3 | Autophagy | Fragmentation | Proteins | Lymphocytes | DNA fragmentation | Cell cycle | Fibroblasts | Ataxia | Inhibition | Deoxyribonucleic acid--DNA | CHK2 protein | Keratinocytes | Caspase | Cell division | Pharmacology | siRNA | Dentistry | Biological activity | Protein kinase | Human performance | Caspase-9 | Cytolethal distending toxin | Hypoxia | Ataxia telangiectasia mutated protein | Transduction | Viability | Deoxyribonucleic acid | DNA
Journal Article
Journal Article