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1. Full Text Progress in Understanding Atopic Dermatitis
by Hanifin, Jon M
Journal of Investigative Dermatology, ISSN 0022-202X, 12/2018, Volume 138, Issue 12, pp. e93 - e95
CELLS | SKIN MICROBIOME | INFLAMMATION | RISK | EPIDERMAL BARRIER | COLONIZATION | DERMATOLOGY
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2. Adult-Onset Atopic Dermatitis: Fact or Fancy?
by Hanifin, JM
DERMATOLOGIC CLINICS, ISSN 0733-8635, 07/2017, Volume 35, Issue 3, pp. 299 - 299
Atopic dermatitis therapy can be a challenge in many cases. Persistence into adulthood often reflects the more severe cases and such patients have the added... 
Systemic therapy | Topical therapy | Atopic dermatitis | Eczema | PREVALENCE | HAND ECZEMA | DERMATOLOGY | Dermatitis, Atopic - diagnosis | Diagnosis, Differential | Dermatitis, Atopic - drug therapy | Humans | Age of Onset | Adult | Secondary Prevention | Administration, Cutaneous | Adrenal Cortex Hormones - therapeutic use
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3. Full Text New drugs for atopic dermatitis may provide clues to basic mechanisms of itch and inflammation
by Hanifin, Jon M., MD
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2016
Dermatology
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4. Full Text Adult eczema prevalence and associations with asthma and other health and demographic factors: A US population–based study
by Silverberg, Jonathan I., MD, PhD, MPH and Hanifin, Jon M., MD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 132, Issue 5, pp. 1132 - 1138
Background Little is known about the epidemiology of eczema in adults. The goal of this study was to determine the prevalence of and associations with adult... 
Allergy and Immunology | race | ethnicity | atopic dermatitis | asthma | rhinoconjunctivitis | dermatitis | atopic disease | birthplace | Eczema | Hispanic | socioeconomic status | hay fever | age | UNITED-STATES | RISK-FACTORS | CHILDHOOD ECZEMA | IMMUNOLOGY | ATOPIC-DERMATITIS | ALLERGY | JAPANESE ADULTS | DISEASE | COHORT | BIRTH | YOUNG-CHILDREN | United States - epidemiology | Eczema - complications | Prevalence | Humans | Middle Aged | Risk Factors | Hypersensitivity, Immediate - complications | Young Adult | Eczema - epidemiology | Asthma - complications | Adolescent | Aged, 80 and over | Hypersensitivity, Immediate - epidemiology | Adult | Aged | Population Surveillance | Asthma - epidemiology | Adults | Prevalence studies (Epidemiology) | Asthma | Health insurance | Family income | Households | Health care policy | Data processing | Statistical methods | Secondary schools | Hay fever | Educational attainment | Ethnicity | Education | Population | Age
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5. Food Allergy in Infants With Atopic Dermatitis: Limitations of Food-Specific IgE Measurements
by Spergel, Jonathan M and Boguniewicz, Mark and Schneider, Lynda and Hanifin, Jon M and Paller, Amy S and Eichenfield, Lawrence F
Pediatrics, ISSN 0031-4005, 12/2015, Volume 136, Issue 6, pp. e1530 - e1530
Children with atopic dermatitis (AD) have a higher risk for development of food allergies. The objective of this study was to examine incidence of food allergy... 
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6. Full Text Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention
by Simpson, Eric L., MD, MCR and Chalmers, Joanne R., PhD and Hanifin, Jon M., MD and Thomas, Kim S., PhD and Cork, Michael J., PhD, FRCP and McLean, W.H. Irwin, FRSE, FMedSci and Brown, Sara J., MRCP, MD and Chen, Zunqiu, MS and Chen, Yiyi, PhD and Williams, Hywel C., DSc, FMedSci
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 4, pp. 818 - 823
Background Atopic dermatitis (atopic eczema) is a chronic inflammatory skin disease that has reached epidemic proportions in children worldwide and is... 
Allergy and Immunology | eczema | emollients | skin barrier | Atopic dermatitis | prevention | SUNFLOWER SEED OIL | FILAGGRIN | IMMUNOLOGY | CARE | CHILDREN | CREAM | ALLERGY | INFANTS | PETROLATUM | HEALTH | EXPOSURE | Emollients - administration & dosage | Emollients - immunology | Follow-Up Studies | United States | Humans | Infant | Risk | Treatment Outcome | United Kingdom | Dermatitis, Atopic - prevention & control | Feasibility Studies | Incidence | Dermatitis, Atopic - immunology | Emollients - adverse effects | Infant, Newborn | Skin - drug effects | Skin - pathology | Skin - immunology | Prevention | Dermatology | Formulae, receipts, prescriptions | Dermatologic agents | Skin | Medicine, Preventive | Public health | Preventive health services | Food allergies | Laboratories | Eczema | Mutation | Dermatitis | Allergies | Children & youth | Atopic Dermatitis and Skin Disease
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7. Full Text Obituary of Georg Rajka: March 10, 1925–March 16, 2013
by Thestrup-Pedersen, Kristian, MD, PhD and Hanifin, Jon M., MD
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2013, Volume 69, Issue 5, pp. e279 - e279
Dermatology | DERMATOLOGY
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8. Full Text Commentary: New drugs for atopic dermatitis may provide clues to basic mechanisms of itch and inflammation
by Hanifin, Jon M
Journal of the American Academy of Dermatology, ISSN 0190-9622, 09/2016, Volume 75, Issue 3, pp. 504 - 505
pruritus | atopic dermatitis | phosphodiesterase | inflammation | immune responses | VITRO | INHIBITION | DISEASE | HISTAMINE-RELEASE | CYCLIC-AMP-PHOSPHODIESTERASE | DERMATOLOGY | Phosphodiesterase Inhibitors - therapeutic use | Drug Administration Schedule | Phosphodiesterase Inhibitors - adverse effects | Humans | Male | Treatment Outcome | Clinical Trials as Topic | Dermatitis, Atopic - physiopathology | Forecasting | Dose-Response Relationship, Drug | Pruritus - physiopathology | Dermatitis, Atopic - drug therapy | Inflammation - drug therapy | Pruritus - drug therapy | Dermatitis, Atopic - immunology | Female | Inflammation - physiopathology | Drug therapy | Atopic dermatitis
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9. Full Text Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report
by Boyce, Joshua A., MD and Assa'ad, Amal, MD and Burks, A. Wesley, MD and Jones, Stacie M., MD and Sampson, Hugh A., MD and Wood, Robert A., MD and Plaut, Marshall, MD and Cooper, Susan F., MSc and Fenton, Matthew J., PhD and Arshad, S. Hasan, MBBS, MRCP, DM, FRCP and Bahna, Sami L., MD, DrPH and Beck, Lisa A., MD and Byrd-Bredbenner, Carol, PhD, RD, FADA and Camargo, Carlos A., MD, DrPH and Eichenfield, Lawrence, MD and Furuta, Glenn T., MD and Hanifin, Jon M., MD and Jones, Carol, RN, AE-C and Kraft, Monica, MD and Levy, Bruce D., MD and Lieberman, Phil, MD and Luccioli, Stefano, MD and McCall, Kathleen M., BSN, RN and Schneider, Lynda C., MD and Simon, Ronald A., MD and Simons, F. Estelle R., MD and Teach, Stephen J., MD, MPH and Yawn, Barbara P., MD, MPH, MSc and Schwaninger, Julie M., MSc and NIAID-Sponsored Expert Panel
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 126, Issue 6, pp. 1105 - 1118
  First-line and adjuvant treatment for food-induced anaphylaxis1114 6.3.2. Despite the risk of severe allergic reactions and even death, there is no current... 
Allergy and Immunology | ALLERGY | IMMUNOLOGY | Food Hypersensitivity - therapy | United States | Humans | National Institute of Allergy and Infectious Diseases (U.S.) | Expert Testimony | Food Hypersensitivity - diagnosis | Food Hypersensitivity - physiopathology | Allergens | Food allergy | Medical colleges | Care and treatment | Safety and security measures | Emergency medicine | Practice guidelines (Medicine) | Respiratory agents | Asthma | Government finance | Diagnosis | Children | Arctic peoples | Health aspects | Monoglycerides | Food | Food allergies | Disease | Oxygen therapy | Comorbidity | Family medical history | Epidemiology | Patients | Allergies | Tropical diseases | Proteins | Medicine | Disease prevention | Celiac disease | Drug therapy | Drug dosages
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10. Full Text Anti–Interleukin-31 Receptor A Antibody for Atopic Dermatitis
by Ruzicka, Thomas and Hanifin, Jon M and Furue, Masutaka and Pulka, Grazyna and Mlynarczyk, Izabela and Wollenberg, Andreas and Galus, Ryszard and Etoh, Takafumi and Mihara, Ryosuke and Yoshida, Hiroki and Stewart, Jonathan and Kabashima, Kenji and XCIMA Study Grp and XCIMA Study Group
The New England Journal of Medicine, ISSN 0028-4793, 03/2017, Volume 376, Issue 9, pp. 826 - 835
In a phase 2, placebo-controlled trial, nemolizumab, an antibody against interleukin-31 receptor A, reduced pruritus in patients with moderate-to-severe atopic... 
VISUAL ANALOG SCALE | ACTIGRAPHY | MEDICINE, GENERAL & INTERNAL | ITCH | ECZEMA | SUICIDAL IDEATION | PRURITUS | INTERLEUKIN-31 RECEPTOR | SKIN | T-CELLS | IL-31 | Antibodies, Monoclonal, Humanized - adverse effects | Receptors, Interleukin - immunology | Humans | Middle Aged | Male | Receptors, Interleukin - antagonists & inhibitors | Antibodies, Monoclonal, Humanized - administration & dosage | Dermatitis, Atopic - drug therapy | Pruritus - drug therapy | Intention to Treat Analysis | Adult | Female | Edema - chemically induced | Usage | Care and treatment | Interleukins | Atopic dermatitis | Diagnosis | Pruritus | Patients | Health aspects | Immunoglobulins | Cytokines | Body weight | Eczema | Clinical trials | Surface area | Drug therapy | Dermatitis
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11. Full Text Tight junction defects in patients with atopic dermatitis
by De Benedetto, Anna, MD and Rafaels, Nicholas M., MS and McGirt, Laura Y., MD and Ivanov, Andrei I., PhD and Georas, Steve N., MD and Cheadle, Chris, PhD and Berger, Alan E., PhD and Zhang, Kunzhong, PhD and Vidyasagar, Sadasivan, MD, PhD and Yoshida, Takeshi, PhD and Boguniewicz, Mark, MD and Hata, Tissa, MD and Schneider, Lynda C., MD and Hanifin, Jon M., MD and Gallo, Richard L., MD and Novak, Natalija, MD and Weidinger, Stephan, MD and Beaty, Terri H., PhD and Leung, Donald Y.M., MD, PhD and Barnes, Kathleen C., PhD and Beck, Lisa A., MD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 127, Issue 3, pp. 773 - 786.e7
Background Atopic dermatitis (AD) is characterized by dry skin and a hyperactive immune response to allergens, 2 cardinal features that are caused in part by... 
Allergy and Immunology | Atopic dermatitis | claudin-1 | tight junctions | EPIDERMAL BARRIER FUNCTION | WATER-LOSS | IMMUNOLOGY | CLAUDIN EXPRESSION | LANGERHANS CELLS | ALLERGY | GENE-EXPRESSION | INTESTINAL BARRIER | SKIN | PERMEABILITY BARRIER | PROTEINS | SINGLE-NUCLEOTIDE POLYMORPHISMS | Immunohistochemistry | Dermatitis, Atopic - genetics | Dermatitis, Atopic - epidemiology | Membrane Proteins - genetics | Humans | Cells, Cultured | Gene Expression Regulation | Male | Dermatitis, Atopic - pathology | Gene Expression Profiling | Claudin-1 | Tight Junctions - immunology | Age of Onset | Dermatitis, Atopic - immunology | Polymerase Chain Reaction | Adult | Female | Membrane Proteins - metabolism | Polymorphism, Single Nucleotide | Phosphates | Allergens | Medical colleges | Care and treatment | RNA | Radiation | Fluorescein | Permeability | Sugars | Monosaccharides | Proteins | Studies | Antigens | Psoriasis | Disease | Skin diseases | Dermatitis | Defects
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12. Full Text Guidelines of care for the management of atopic dermatitis
by Sidbury, Robert, MD and Davis, Dawn M., MD and Cohen, David E., MD and Cordoro, Kelly M., MD and Berger, Timothy G., MD and Bergman, James N., MD and Chamlin, Sarah L., MD, MSCI and Cooper, Kevin D., MD and Feldman, Steven R., MD, PhD and Hanifin, Jon M., MD and Krol, Alfons, MD and Margolis, David J., MD, PhD and Paller, Amy S., MD and Schwarzenberger, Kathryn, MD and Silverman, Robert A., MD and Simpson, Eric L., MD and Tom, Wynnis L., MD and Williams, Hywel C., DSc and Elmets, Craig A., MD and Block, Julie, BA and Harrod, Christopher G., MS and Begolka, Wendy Smith, MBS and Eichenfield, Lawrence F., MD
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2014, Volume 71, Issue 2, pp. 327 - 349
Atopic dermatitis is a chronic, pruritic inflammatory dermatosis that affects up to 25% of children and 2% to 3% of adults. This guideline addresses important... 
Dermatology | interferon gamma | oral antihistamines | oral steroids | photochemotherapy | cyclosporin A | atopic dermatitis | azathioprine | methotrexate | mycophenolate mofetil | phototherapy | systemic therapy | oral antimicrobials | ULTRAVIOLET-B PHOTOTHERAPY | EXTRACORPOREAL PHOTOCHEMOTHERAPY | UVB PHOTOTHERAPY | RANDOMIZED CONTROLLED-TRIAL | DERMATOLOGY | PSORALEN PHOTOCHEMOTHERAPY | DOUBLE-BLIND | THIOPURINE METHYLTRANSFERASE | STAPHYLOCOCCUS-AUREUS | LONG-TERM TREATMENT | MYCOPHENOLATE-MOFETIL | Medical colleges | Antihistamines | Hospitals | Atopic dermatitis | Practice guidelines (Medicine) | Anti-infective agents | Phototherapy
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13. Full Text Evolving Concepts of Pathogenesis in Atopic Dermatitis and Other Eczemas
by Hanifin, Jon M
Journal of Investigative Dermatology, ISSN 0022-202X, 02/2009, Volume 129, Issue 2, pp. 320 - 322
The eczemas represent a common and diverse group of inflammatory skin diseases whose definitions and pathogenic mechanisms have often been confused and... 
HUMAN EPITHELIAL-CELLS | ICHTHYOSIS VULGARIS | FILAGGRIN MUTATIONS | PROLIFERATION | SKIN | EXPRESSION | T-CELLS | IN-SITU | EXPOSURE | THYMIC STROMAL LYMPHOPOIETIN | DERMATOLOGY | Signal Transduction - immunology | Animals | Dermatitis, Atopic - etiology | Eczema - immunology | Humans | Dermatitis, Atopic - immunology | Eczema - etiology | Keratinocytes - immunology
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14. Full Text A reassuring rejoinder against malignant influences of topical calcineurin use in children
by Hanifin, Jon M
JAMA Dermatology, ISSN 2168-6068, 06/2015, Volume 151, Issue 6, pp. 587 - 588
BOX | PREVALENCE | INHIBITORS | DERMATOLOGY | Dermatitis, Atopic - drug therapy | Neoplasms - etiology | Humans | Female | Immunosuppressive Agents - adverse effects | Male | Tacrolimus - analogs & derivatives
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15. Full Text A Randomized, Multi-Center, NIH/NIAID Funded Study To Assess The Immunogenicity Of Fluzone® Intradermal and Intramuscular Vaccines In Atopic Dermatitis
by Leung, Donald Y.M., MD, PhD, FAAAAI and Beck, Lisa A., MD, FAAAAI and Hanifin, Jon M., Dr and Schneider, Lynda C., Dr and Paller, Amy, Dr and David, Gloria, Dr and Monti, Katherine, Ms and Jepson, Brett, Mr and Weinberg, Adriana, Dr
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 133, Issue 2, pp. AB72 - AB72
Allergy and Immunology
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16. Full Text Nemolizumab in patients with moderate-to-severe atopic dermatitis: Randomized, phase II, long-term extension study
by Kabashima, Kenji and Furue, Masutaka and Hanifin, Jon M and Pulka, Grazyna and Wollenberg, Andreas and Galus, Ryszard and Etoh, Takafumi and Mihara, Ryosuke and Nakano, Miwa and Ruzicka, Thomas
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 10/2018, Volume 142, Issue 4, pp. 1121 - 1130.e7
Nemolizumab, an anti–IL-31 receptor A mAb, improved pruritus, dermatitis, and sleep in adults with moderate-to-severe atopic dermatitis that was inadequately... 
pruritus | atopic dermatitis | Monoclonal antibody | IL-31 receptor | nemolizumab | IL-31 | PLACEBO | MANAGEMENT | ECZEMA | GUIDELINES | NATIONAL-HEALTH | RECEPTOR | IMMUNOLOGY | INTERLEUKIN-31 | SKIN BARRIER | CARE | ALLERGY | Viral antibodies | Antibodies | Care and treatment | Pruritus | Atopic dermatitis | Analysis | Edema | FDA approval | Dermatitis | Patients | Asthma | Histamine | Randomization | Sleep | Eczema | Monoclonal antibodies | Population | Skin diseases | Skin | Adults | Safety | Drug dosages
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