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1. Full Text Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes
by Xu, T and Brandmaier, S and Messias, A.C and Herder, C and isma, H.H.M and Demirkan, A and Yu, Z and Ried, J.S and Haller, T and Heier, M and Campillos, M and Fobo, G and Stark, R and Holzapfel, C and Adam, J and Chi, S and Rotter, M and Panni, T and Quante, A.S and He, Y and Prehn, C and Roemisch-Margl, W and Kastenmüller, G and Willemsen, G and Pool, R and Kasa, K and Willems van Dijk, K and Hankemeier, T and Meisinger, C and Thorand, B and Ruepp, A and Hrabé de Angelis, M and Li, Y and Wichmann, H.-E and Stratmann, B and Strauch, K and Metspalu, A and Gieger, C and Suhre, K and Adamski, J and Illig, T and Rathmann, W and Roden, M and Peters, A and van Duijn, C.M and Boomsma, D.I and Meitinger, T and Wang-Sattler, R
Diabetes care, ISSN 0149-5992, 2015, Volume 38, Issue 10, pp. 1858 - 1867
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Hypoglycemic Agents - therapeutic use | Metabolomics | Metformin - therapeutic use | Cross-Sectional Studies | Fatty Acid Desaturases - metabolism | Genomics | Humans | Middle Aged | Risk Factors | Diabetes Mellitus, Type 2 - prevention & control | Genotype | Male | Diabetes Mellitus, Type 2 - blood | Fasting - blood | Lipid Metabolism - drug effects | Cholesterol, LDL - metabolism | Female | Aged | Diabetic Angiopathies - prevention & control | Diabetes Mellitus, Type 2 - drug therapy | Type 2 diabetes | Prevention | Care and treatment | Cholesterol, LDL | Influence | Dosage and administration | Metformin | Cardiovascular diseases | Disease prevention | Metabolites | Cardiovascular disease | Pharmacology | Diabetes | Low density lipoprotein | Risk factors | Index Medicus
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2. Full Text Next-generation capillary electrophoresis–mass spectrometry approaches in metabolomics
by Zhang, Wei and Hankemeier, Thomas and Ramautar, Rawi
Current opinion in biotechnology, ISSN 0958-1669, 2016, Volume 43, pp. 1 - 7
Internal Medicine | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Biochemical Research Methods | Science & Technology | Metabolome | Animals | Electrophoresis, Capillary - methods | Spectrometry, Mass, Electrospray Ionization - methods | Metabolomics - methods | Humans | Mass spectrometry | Electrophoresis | Metabolites | Analysis | Index Medicus
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3. Full Text Numerical Representations of Metabolic Systems
by Smilde, Age K and Hankemeier, Thomas
Analytical chemistry (Washington), ISSN 0003-2700, 10/2020, Volume 92, Issue 20, pp. 13614 - 13621
Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology | Analytical chemistry | Metabolomics | Questions | Proteomics | Index Medicus
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4. Full Text Interstitial Flow Recapitulates Gemcitabine Chemoresistance in A 3D Microfluidic Pancreatic Ductal Adenocarcinoma Model by Induction of Multidrug Resistance Proteins
by Kramer, Bart and de Haan, Luuk and Vermeer, Marjolein and Olivier, Thomas and Hankemeier, Thomas and Vulto, Paul and Joore, Jos and Lanz, Henriette L
International journal of molecular sciences, ISSN 1422-0067, 09/2019, Volume 20, Issue 18, p. 4647
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Microfluidic Analytical Techniques | Pancreatic Neoplasms - metabolism | Intestine, Small - pathology | Humans | Pancreatic Neoplasms - pathology | Carcinoma, Pancreatic Ductal - metabolism | Deoxycytidine - pharmacology | Lab-On-A-Chip Devices | Neoplasm Proteins - metabolism | Carcinoma, Pancreatic Ductal - pathology | ATP Binding Cassette Transporter, Subfamily B - metabolism | Models, Biological | Cell Line, Tumor | Intestine, Small - metabolism | Deoxycytidine - analogs & derivatives | Drug Resistance, Neoplasm - drug effects | Adenocarcinoma | Cell culture | Gemcitabine | Image processing | Multidrug resistance | Cytology | Chemoresistance | Fluorescence | Breast cancer | Metastasis | Gene expression | Cancer therapies | Metastases | Chemotherapy | Light beams | Bleaching | Pancreatic cancer | Morphology | Viability | Three dimensional models | Microfluidics | Tumors | Index Medicus | chemoresistance | modeling | interstitial flow | gemcitabine | cancer | microfluidics | pancreatic ductal adenocarcinoma
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5. Full Text Microfluidic 3D cell culture: from tools to tissue models
by van Duinen, Vincent and Trietsch, Sebastiaan J and Joore, Jos and Vulto, Paul and Hankemeier, Thomas
Current opinion in biotechnology, ISSN 0958-1669, 2015, Volume 35, pp. 118 - 126
Internal Medicine | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Biochemical Research Methods | Science & Technology | Microfluidic Analytical Techniques | Animals | Biomimetics | Tissue Culture Techniques | Coculture Techniques | Humans | Cell Culture Techniques - methods | Microfluidics - methods | Neoplasms | Microfluidics | Index Medicus
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6. Full Text Profiling nucleotides in low numbers of mammalian cells by sheathless CE–MS in positive ion mode: Circumventing corona discharge
by Zhang, Wei and Guled, Faisa and Hankemeier, Thomas and Ramautar, Rawi
Electrophoresis, ISSN 0173-0835, 03/2020, Volume 41, Issue 5-6, pp. 360 - 369
mass spectrometry | HepG2 cells | nucleotides | corona discharge circumvention | sheathless interface | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Phosphates | Ammonium acetate | Profiling | Adenine | Amino acids | Ions | Nucleotides | Mammals | Positive ions | Discharge | Biological materials | Electrolytic cells | Negative ions | Nicotinamide | Emitters | Index Medicus
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7. Full Text Automated microfluidic cell culture of stem cell derived dopaminergic neurons
by Kane, Khalid I. W and Moreno, Edinson Lucumi and Hachi, Siham and Walter, Moriz and Jarazo, Javier and Oliveira, Miguel A. P and Hankemeier, Thomas and Vulto, Paul and Schwamborn, Jens C and Thoma, Martin and Fleming, Ronan M. T
Scientific reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1796 - 1796
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell culture | Automation | Dopamine | Mesencephalon | Neurodegenerative diseases | Neurons | Stem cells | Quality control | Electrophysiology | Calcium imaging | Dopamine receptors | Index Medicus
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8. Full Text Feasibility of ultra-performance liquid chromatography–ion mobility–time-of-flight mass spectrometry in analyzing oxysterols
by Kylli, Petri and Hankemeier, Thomas and Kostiainen, Risto
Journal of Chromatography A, ISSN 0021-9673, 03/2017, Volume 1487, pp. 147 - 152
Fibroblast cell samples | Derivatization | Liquid-chromatography-ion-mobility-mass-spectrometry,oxysterol | Oxysterol isomers | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Oxysterols - analysis | Spectrometry, Mass, Electrospray Ionization | Humans | Mass Spectrometry | Chromatography, Liquid | Isomerism | Fibroblasts - chemistry | Isocyanates | Liquid chromatography | Mass spectrometry | Analysis
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9. Full Text Mass appeal: metabolite identification in mass spectrometry-focused untargeted metabolomics
by Dunn, Warwick B and Erban, Alexander and Weber, Ralf J.M and Creek, Darren J and Brown, Marie and Breitling, Rainer and Hankemeier, Thomas and Goodacre, Royston and Neumann, Steffen and Kopka, Joachim and Viant, Mark R
Metabolomics, ISSN 1573-3882, 2013, Volume 9, Issue 1, pp. S44 - S66
Ultra performance liquid chromatography | Gas chromatography | Metabolomics | Metabolite identification | Capillary electrophoresis | Liquid chromatography | DIMS | Mass spectrometry | Structure elucidation | Biochemistry, general | Biomedicine general | Cell Biology | Life Sciences | Molecular Medicine | Developmental Biology | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Plant physiology | Metabolites
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10. Full Text On-line coupling of two-phase microelectroextraction to capillary electrophoresis – Mass spectrometry for metabolomics analyses
by Oedit, Amar and Hankemeier, Thomas and Lindenburg, Peter W
Microchemical journal, ISSN 0026-265X, 03/2021, Volume 162
Electromembrane extraction | Metabolomics | Capillary electrophoresis | Bioanalysis | Single-drop microextraction | Electroextraction
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