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science & technology (34) 34
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1. Full Text Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus
by Frimodt-Moller, Niels and Taboureau, Olivier and Christensen, Bjarke and De Maria, Leonardo and Kjærulff, Søren and Kristensen, Hans-Henrik and Lehrer, Robert I and Mygind, Per H and Zasloff, Michael and Christensen, Bjørn E and Raventós, Dorotea and Sørensen, Marianne V and Fischer, Rikke L and Ludvigsen, Svend and Yaver, Debbie and Hansen, Mogens T and Schnorr, Kirk M and Elvig-Jørgensen, Signe G and Sönksen, Carsten P and Buskov, Steen
Nature, ISSN 0028-0836, 10/2005, Volume 437, Issue 7061, pp. 975 - 980
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | Pharmacognosy. Homeopathy. Health food | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Pneumococcal Infections - drug therapy | Amino Acid Sequence | Gram-Positive Bacteria - physiology | Peptides | Gram-Positive Bacteria - drug effects | Humans | DNA, Complementary - genetics | Molecular Sequence Data | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Defensins - chemistry | Fungi - chemistry | Recombinant Proteins - pharmacology | Fungi - genetics | Recombinant Proteins - isolation & purification | Anti-Bacterial Agents - therapeutic use | Animals | Anti-Bacterial Agents - chemistry | Cloning, Molecular | Pneumococcal Infections - microbiology | Anti-Bacterial Agents - pharmacology | Mice | Disease Models, Animal | Fungi | Antibiotics | Index Medicus
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2. Full Text The emerging roles of YAP and TAZ in cancer
by Moroishi, Toshiro and Hansen, Carsten Gram and Guan, Kun-Liang
Nature reviews. Cancer, ISSN 1474-175X, 01/2015, Volume 15, Issue 2, pp. 73 - 79
Life Sciences & Biomedicine | Oncology | Science & Technology | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Cytoskeletal Proteins - genetics | Humans | Protein-Serine-Threonine Kinases - genetics | GTP-Binding Protein alpha Subunits - genetics | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | Neoplasms - genetics | Wnt Signaling Pathway - genetics | Cell Transformation, Neoplastic - genetics | GTP-Binding Protein alpha Subunits, Gq-G11 | Adaptor Proteins, Signal Transducing - genetics | MicroRNAs - genetics | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Apoptosis | Physiological aspects | Cellular proteins | Development and progression | Research | Cancer | Index Medicus
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3. Full Text Disease and the Hippo Pathway: Cellular and Molecular Mechanisms
by Hansen, Carsten Gram
2019, ISBN 3039217771
STRIPAK | skin cancer | n/a | Lats2 | transcription | myofibroblast | epigenetic | Hippo | cancer immunity | TAZ | TAZ (transcriptional co-activator with PDZ-binding motif) | adaptive immunity | fibroblasts | innate immunity | LATS | MST (mammalian STE20-like protein kinase) | phosphorylation | stem cells | wound healing | signal transduction | angiogenesis | LATS1/2 | EMT | protein-protein interactions | structure biology | hippo pathway | autoimmunity | Mps one binder | YAP/TAZ | GPCR | fibrosis | MST1/2 | YAP (yes-associated protein) | YAP | protein kinase | LATS (large tumor suppressor kinase) | peripheral nerve sheath tumor | signal cross-talk | stem cell | skin development | STK38 | tumorigenesis | NDR | schwannoma | G protein-coupled receptor | anti-cancer therapy | feedback loops | vascular mimicry | castration resistance | chromatin | Hippo signalling | ECM | MST | prostate cancer | TEAD | cancer | zebrafish
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4. Full Text Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway
by Mo, Jung-Soon and Meng, Zhipeng and Kim, Young Chul and Park, Hyun Woo and Hansen, Carsten Gram and Kim, Soohyun and Lim, Dae-Sik and Guan, Kun-Liang
Nature cell biology, ISSN 1465-7392, 04/2015, Volume 17, Issue 4, pp. 500 - 510
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phosphorylation | Humans | Phosphoproteins - antagonists & inhibitors | Phosphoproteins - metabolism | DNA-Binding Proteins - metabolism | RNA Interference | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Cell Transformation, Neoplastic - genetics | HEK293 Cells | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Nuclear Proteins - metabolism | Phosphoproteins - genetics | Transcription Factors - genetics | Transcription Factors - metabolism | Animals | Energy Metabolism | Mice, Nude | Adaptor Proteins, Signal Transducing - genetics | Mice | RNA, Small Interfering | Enzyme Activation | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | 3T3 Cells | AMP-Activated Protein Kinases - genetics | Cytoplasm | Cell metabolism | Cellular proteins | Stress (Physiology) | Genetic aspects | Properties | Index Medicus
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5. Full Text YAP and TAZ: a nexus for Hippo signaling and beyond
by Hansen, Carsten Gram and Moroishi, Toshiro and Guan, Kun-Liang
Trends in cell biology, ISSN 0962-8924, 2015, Volume 25, Issue 9, pp. 499 - 513
Pathology | stem cells | Wnt | regeneration | primary cilia | extracellular matrix | Notch | Regeneration | Extracellular matrix | Primary cilia | Stem cells | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Adaptor Proteins, Signal Transducing - physiology | Transcription Factors - physiology | Animals | Signal Transduction | Protein-Serine-Threonine Kinases - physiology | Humans | Transcriptional Activation | Stress, Physiological | Intestines - metabolism | Phosphoproteins - physiology | Cells | Index Medicus
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6. Full Text Special Issue on "Disease and the Hippo Pathway"
by Hansen, Carsten Gram
Cells (Basel, Switzerland), ISSN 2073-4409, 10/2019, Volume 8, Issue 10, p. 1179
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus | n/a
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7. Full Text Deletion of cavin genes reveals tissue-specific mechanisms for morphogenesis of endothelial caveolae
by Hansen, Carsten Gram and Shvets, Elena and Howard, Gillian and Riento, Kirsi and Nichols, Benjamin James
Nature communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 1831 - 1831
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Molecular Weight | RNA-Binding Proteins | Lung - cytology | Morphogenesis | Endothelial Cells - ultrastructure | Multiprotein Complexes - metabolism | Cell Shape | Gene Deletion | Myocardium - metabolism | Protein Structure, Quaternary | Lung - ultrastructure | Lung - metabolism | Myocardium - ultrastructure | Caveolae - metabolism | Caveolin 1 - chemistry | Endothelial Cells - metabolism | Membrane Proteins - genetics | Mice, Inbred C57BL | Endothelium - growth & development | Organ Specificity | Mice, Knockout | Caveolin 1 - metabolism | Animals | Endothelium - metabolism | Endothelium - ultrastructure | Endothelial Cells - cytology | Mice | Index Medicus
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8. Full Text The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1
by Hansen, Carsten Gram and Ng, Yuen Lam Dora and Lam, Wai-Ling Macrina and Plouffe, Steven W and Guan, Kun-Liang
Cell research, ISSN 1001-0602, 12/2015, Volume 25, Issue 12, pp. 1299 - 1313
mTOR | LAT1/CD98 | SLC7A5 | YAP | amino acid | Hippo | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Proliferation | Signal Transduction | TOR Serine-Threonine Kinases - metabolism | Humans | Cells, Cultured | Intracellular Signaling Peptides and Proteins - metabolism | Phosphoproteins - genetics | Phosphoproteins - metabolism | Mechanistic Target of Rapamycin Complex 1 | Amino Acids - metabolism | Multiprotein Complexes - metabolism | Adaptor Proteins, Signal Transducing - genetics | HEK293 Cells | Adaptor Proteins, Signal Transducing - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Index Medicus | LAT1 | Original | CD98
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9. Full Text Dynamic caveolae exclude bulk membrane proteins and are required for sorting of excess glycosphingolipids
by Shvets, Elena and Bitsikas, Vassilis and Howard, Gillian and Hansen, Carsten Gram and Nichols, Benjamin J
Nature communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, pp. 6867 - 6867
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Membrane | Green Fluorescent Proteins | NIH 3T3 Cells | Membrane Proteins - genetics | Humans | Caveolin 1 - genetics | Gene Expression Regulation - physiology | Recombinant Proteins | Caveolin 1 - metabolism | Animals | Glycosphingolipids - metabolism | Membrane Proteins - metabolism | Mice | HeLa Cells | Genome | Luminescent Proteins | Photobleaching | Index Medicus
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