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American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 2016, Volume 193, Issue 12, pp. 1410 - 1420
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 06/2016, Volume 193, Issue 12, pp. 1410 - 1420
Rationale: Altered pulmonary hemodynamics and fluid flow-induced high shear stress (HSS) are characteristic hallmarks in the pathogenesis of pulmonary arterial... 
Journal Article
European Respiratory Journal, ISSN 0903-1936, 2017, Volume 50, Issue 2, pp. 1700806 - 1700806
Lung resection is a standard treatment in patients with clinical stages I and II and selected patients with stage IIIA nonsmall cell lung cancer [1]. Major... 
PNEUMONECTOMY | RESPIRATORY SYSTEM | Vascular Remodeling | Humans | Drug Therapy | Male | Lung Neoplasms - therapy | Pneumonectomy | Radiotherapy | Rats, Sprague-Dawley | Pulmonary Circulation | Carcinoma, Non-Small-Cell Lung - therapy | Animals | Adult | Female | Aged | Lung - blood supply | Lung - surgery | Comparative studies | Pulmonary arteries | Heart diseases | Lung cancer | Pulmonary artery
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2015, Volume 65, Issue 7, pp. 668 - 680
Abstract Background Endothelial cell (EC) dysfunction plays a central role in the pathogenesis of pulmonary arterial hypertension (PAH), promoting... 
Cardiovascular | Internal Medicine | β-blocker | nebivolol | inflammation | endothelial dysfunction | pulmonary hypertension | CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | beta-blocker | RATS | CROSS-TALK | THERAPY | SMOOTH-MUSCLE HYPERPLASIA | ARTERIAL-HYPERTENSION | ANIMAL-MODELS | BLOCKADE | PROGRESSION | Ethanolamines - pharmacology | Benzopyrans - therapeutic use | Cell Proliferation | Rats, Wistar | Metoprolol - pharmacology | Humans | Monocrotaline | Adrenergic beta-1 Receptor Antagonists - pharmacology | Hypertension, Pulmonary - physiopathology | Endothelium, Vascular - drug effects | Male | Adrenergic beta-1 Receptor Antagonists - therapeutic use | Hypertension, Pulmonary - drug therapy | Cell Culture Techniques | Vascular Remodeling - drug effects | Benzopyrans - pharmacology | Disease Models, Animal | Nebivolol | Endothelium, Vascular - physiopathology | Rats | Metoprolol - therapeutic use | Pulmonary Artery - physiopathology | Pulmonary Artery - drug effects | Animals | Myocytes, Smooth Muscle | Cell Communication - drug effects | Endothelium, Vascular - pathology | Ethanolamines - therapeutic use | Hypertension, Pulmonary - pathology | Pulmonary Artery - pathology | Endothelial Cells - drug effects | Heart | Sects | Pulmonary hypertension | Endothelium | Studies | Cell growth | Pulmonary arteries | Mortality | Smooth muscle | Veins & arteries | Life Sciences
Journal Article
Journal Article
by Angliss, Robyn P and Ferguson, Megan C and Appel, Cara L and Brown, Jeremy and Bortot, Claire and Bean, William T and Moriarty, Katie M and Matthews, Sean M and Green, David S and Anderson, Stacy and King, Evan and Yaeger, J Scott and Arismendi, Ivan and Arismendi, Ivan and Gregory, Stan and Wildman, Randy and Ashkenas, Linda and Anderson, David and Shuster, Laurie and Evenson, Joseph R and Huggins, Jessica L and Calambokidis, John and Ashton, Don and Mcbain, Scott and Railsback, Steve and Ashton, Don and Bury, R. Bruce and Bury, Gwen W and Baker, C. Scott and Sremba, Angie and Pallin, Logan and Atkinson, Shannon and Rogan, Andy and Kerr, Iain and Bettaso, Jamie B and Garwood, Justin M and Bourque, Ryan M and West, Christopher J and Bingham, Daniel M and Sepulveda, Adam and Painter, Sally and Bredeweg, Evan M and Garcia, Tiffany S and Morzillo, Anita T and Schumaker, Nathan and Buchanan, Joseph B and Bury, R. Bruce and Bury, Gwen W and Ashton, Don T and Bettaso, James and Germano, David J and Slavens, Frank and Slavens, Kate and Bury, Gwen W and Bury, Gwendolynn W and Ilharreguy, Arianna and Arismendi, Ivan and Bury, R. Bruce and Calambokidis, John and Flynn, Kiirsten and Steiger, Gretchen and Dobson, Elana and Malleson, Mark and Gisborne, Brian and Berta, Susan and Calambokidis, John and Perez, Alie and Camp, Meghan and Shipley, Lisa A and Varner, Johanna and Chestnut, Tara and Chestnut, Tara and Connors, Patrice K and Light, Jessica E and Tanis, Brian P and Drew, Joshua A and Anderson, Chris N and Perry, Anali M and Henning, Charon E and Casillas, Mary and Hinde, Katie and Clair, C. Toby St and Routledge, Kyle and Palmer, Charlie and Martinez-Nunez, Felix and Cousins, Christopher and Garcia, Tiffany and Bredeweg, Evan and Levi, Taal and Allen, Jennifer and Dodds, Jeanne and Ernest, Kristina and Escajeda, Erica and Stafford, Kate and Woodgate, Rebecca and Laidre, Kristin and Froschauer, Ann and Hogan, Bronwyn and Dickerson, Kimberly and Smith-Castro, Jennifer and ...
Northwestern Naturalist, ISSN 1051-1733, 07/2019, Volume 100, Issue 2, p. 132
Journal Article
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 11/2017, Volume 57, Issue 5, pp. 603 - 614
Although p38 mitogen-activated protein kinase (MAPK) is known to have a role in ischemic heart disease and many other diseases, its contribution to the... 
P38 MAPK | SMADs | MRTF-A | Right ventricle | Pulmonary hypertension | CARDIAC-FUNCTION | FIBROSIS | MYOCARDIAL-INFARCTION | PULMONARY ARTERIAL-HYPERTENSION | pulmonary hypertension | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | HYPOXIA | p38 MAPK | FAILURE | CELL BIOLOGY | right ventricle | RESPIRATORY SYSTEM | IN-VIVO | MYOFIBROBLAST TRANSDIFFERENTIATION | TRANSCRIPTION FACTOR | Heart - physiopathology | Mice, Inbred C57BL | Hypertension, Pulmonary - metabolism | Hypertrophy, Right Ventricular - enzymology | MAP Kinase Signaling System | Collagen - metabolism | Hypertrophy, Right Ventricular - physiopathology | Animals | Cell Transdifferentiation - physiology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mice | p38 Mitogen-Activated Protein Kinases - metabolism | Ventricular Function, Right - physiology | Fibroblasts - metabolism | Immunohistochemistry | Heart | Phosphorylation | Transcription factors | Heart attacks | Cardiomyopathy | Pathogenesis | Cardiovascular disease | Smad3 protein | Kinases | Western blotting | Proteins | Signal transduction | Ischemia | Smad2 protein | Fibroblasts | Heart diseases | Growth factors | Echocardiography | Deactivation | Pulmonary arteries | MAP kinase | Histology | siRNA | Patients | Pressure | Coronary artery disease | Nuclear transport | Pulmonary artery | Studies | Banding | Protein kinase | Collagen | Fibrosis | Hypoxia | Ventricle | Immunofluorescence | Hypertrophy | Veins & arteries
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2018, Volume 19, Issue 9, p. 2585
Journal Article