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1. Full Text Media and the health care system
by Haraldsson, Magnus
Laeknabladid, ISSN 0023-7213, 11/2018, Volume 104, Issue 11, pp. 487 - 487
Mass Media | Delivery of Health Care | Humans | Iceland | Index Medicus
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2. Full Text CNVs conferring risk of autism or schizophrenia affect cognition in controls
by Stefansson, Hreinn and Meyer-Lindenberg, Andreas and Steinberg, Stacy and Magnusdottir, Brynja and Morgen, Katrin and Arnarsdottir, Sunna and Bjornsdottir, Gyda and Walters, G. Bragi and Jonsdottir, Gudrun A and Doyle, Orla M and Tost, Heike and Grimm, Oliver and Kristjansdottir, Solveig and Snorrason, Heimir and Davidsdottir, Solveig R and Gudmundsson, Larus J and Jonsson, Gudbjorn F and Stefansdottir, Berglind and Helgadottir, Isafold and Haraldsson, Magnus and Jonsdottir, Birna and Thygesen, Johan H and Schwarz, Adam J and Didriksen, Michael and Stensbøl, Tine B and Brammer, Michael and Kapur, Shitij and Halldorsson, Jonas G and Hreidarsson, Stefan and Saemundsen, Evald and Sigurdsson, Engilbert and Stefansson, Kari
Nature, ISSN 0028-0836, 2014, Volume 505, Issue 7483, pp. 361 - 366
In a small fraction of patients with schizophrenia or autism, alleles of copy-number variants (CNVs) in their genomes are probably the strongest factors... 
METAANALYSIS | RELATIVES | PSYCHOSIS | MULTIDISCIPLINARY SCIENCES | RECURRENT MICRODELETIONS | SPATIAL WORKING-MEMORY | 16P11.2 | GLOBAL ASSESSMENT | DEFICITS | 15Q11.2 | Brain - anatomy & histology | Humans | Middle Aged | Male | Brain - abnormalities | Case-Control Studies | Iceland | Brain - metabolism | Young Adult | Fertility - genetics | Schizophrenia - genetics | Cognition - physiology | Adult | Female | Autistic Disorder - genetics | Chromosome Deletion | Genetic Predisposition to Disease | Chromosomes, Human - genetics | DNA Copy Number Variations - genetics | Chromosomes, Human, Pair 15 - genetics | Dyslexia - genetics | Neuropsychological Tests | Magnetic Resonance Imaging | Phenotype | Adolescent | Heterozygote | Learning Disorders - genetics | Aged | Autism | Copy number variations | Physiological aspects | Schizophrenia | Dyslexia | Genetic aspects | Cognition | Research | Population | Cognition & reasoning | Disease | Memory | Index Medicus
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3. Full Text Large recurrent microdeletions associated with schizophrenia
by Stefansson, Hreinn and Rujescu, Dan and Cichon, Sven and Pietiläinen, Olli P. H and Ingason, Anes and Steinberg, Stacy and Fossdal, Ragnheidur and Sigurdsson, Engilbert and Sigmundsson, Thordur and Buizer-Voskamp, Jacobine E and Hansen, Thomas and Jakobsen, Klaus D and Muglia, Pieranea and Francks, Clyde and Matthews, Paul M and Gylfason, Arnaldur and Halldorsson, Bjarni V and Gudbjartsson, Daniel and Thorgeirsson, Thorgeir E and Sigurdsson, Asgeir and Jonasdottir, Adalbjorg and Jonasdottir, Aslaug and Bjornsson, Asgeir and Mattiasdottir, Sigurborg and Blondal, Thorarinn and Haraldsson, Magnus and Magnusdottir, Brynja B and Giegling, Ina and Möller, Hans-Jürgen and Hartmann, Annette and Shianna, Kevin V and Ge, Dongliang and Need, Anna C and Crombie, Caroline and Fraser, Gillian and Walker, Nicholas and Lonnqvist, Jouko and Suvisaari, Jaana and Tuulio-Henriksson, Annamarie and Paunio, Tiina and Toulopoulou, Timi and Bramon, Elvira and Di Forti, Marta and Murray, Robin and Ruggeri, Mirella and Vassos, Evangelos and Tosato, Sarah and Walshe, Muriel and Li, Tao and Vasilescu, Catalina and Mühleisen, Thomas W and Wang, August G and Ullum, Henrik and Djurovic, Srdjan and Melle, Ingrid and Olesen, Jes and Kiemeney, Lambertus A and Franke, Barbara and Sabatti, Chiara and Freimer, Nelson B and Gulcher, Jeffrey R and Thorsteinsdottir, Unnur and Kong, Augustine and Aneassen, Ole A and Ophoff, Roel A and Georgi, Alexander and Rietschel, Marcella and Werge, Thomas and Petursson, Hannes and Goldstein, David B and Nöthen, Markus M and Peltonen, Leena and Collier, David A and St Clair, David and Stefansson, Kari and Kahn, René S and Linszen, Don H and van Os, Jim and Wiersma, Durk and Bruggeman, Richard and Cahn, Wiepke and de Haan, Lieuwe and Krabbendam, Lydia and Myin-Germeys, Inez and GROUP
Nature, ISSN 0028-0836, 2008, Volume 455, Issue 7210, pp. 232 - 236
Reduced fecundity, associated with severe mental disorders, places negative selection pressure on risk alleles and may explain, in part, why common variants... 
AMPLIFICATION | GENOMIC DISORDERS | MULTIDISCIPLINARY SCIENCES | GENES | FRAGILE-X-SYNDROME | PHENOTYPE | DEFICIT | LINKAGE ANALYSIS | CHROMOSOMES | DELETION | IMPAIRMENT | Gene Dosage - genetics | Genetic Predisposition to Disease - genetics | Europe | Humans | Genotype | Chromosomes, Human, Pair 15 - genetics | Loss of Heterozygosity | Genome, Human - genetics | Psychotic Disorders - genetics | Schizophrenia - genetics | China | Polymorphism, Single Nucleotide - genetics | Models, Genetic | Chromosomes, Human, Pair 1 - genetics | Sequence Deletion - genetics | Schizophrenia | Genetic aspects | Chromosome deletion | Research | Disease | Patients | Mental retardation | Risk assessment | Fluorescence in situ hybridization | Index Medicus
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4. Full Text Common variants conferring risk of schizophrenia
by Stefansson, Hreinn and Ophoff, Roel A and Steinberg, Stacy and Aneassen, Ole A and Cichon, Sven and Rujescu, Dan and Werge, Thomas and Pietiläinen, Olli P. H and Mors, Ole and Mortensen, Preben B and Sigurdsson, Engilbert and Gustafsson, Omar and Nyegaard, Mette and Tuulio-Henriksson, Annamari and Ingason, Anes and Hansen, Thomas and Suvisaari, Jaana and Lonnqvist, Jouko and Paunio, Tiina and Børglum, Anders D and Hartmann, Annette and Fink-Jensen, Anders and Nordentoft, Merete and Hougaard, David and Norgaard-Pedersen, Bent and Böttcher, Yvonne and Olesen, Jes and Breuer, René and Möller, Hans-Jürgen and Giegling, Ina and Rasmussen, Henrik B and Timm, Sally and Mattheisen, Manuel and Bitter, István and Réthelyi, János M and Magnusdottir, Brynja B and Sigmundsson, Thordur and Olason, Pall and Masson, Gisli and Gulcher, Jeffrey R and Haraldsson, Magnus and Fossdal, Ragnheidur and Thorgeirsson, Thorgeir E and Thorsteinsdottir, Unnur and Ruggeri, Mirella and Tosato, Sarah and Franke, Barbara and Strengman, Eric and Kiemeney, Lambertus A and Melle, Ingrid and Djurovic, Srdjan and Abramova, Lilia and Kaleda, Vasily and Sanjuan, Julio and de Frutos, Rosa and Bramon, Elvira and Vassos, Evangelos and Fraser, Gillian and Ettinger, Ulrich and Picchioni, Marco and Walker, Nicholas and Toulopoulou, Timi and Need, Anna C and Ge, Dongliang and Yoon, Joeng Lim and Shianna, Kevin V and Freimer, Nelson B and Cantor, Rita M and Murray, Robin and Kong, Augustine and Golimbet, Vera and Carracedo, Angel and Arango, Celso and Costas, Javier and Jönsson, Erik G and Terenius, Lars and Agartz, Ingrid and Petursson, Hannes and Nöthen, Markus M and Rietschel, Marcella and Matthews, Paul M and Muglia, Pieranea and Peltonen, Leena and St Clair, David and Goldstein, David B and Stefansson, Kari and Collier, David A and Kahn, René S and Linszen, Don H and van Os, Jim and Wiersma, Durk and Bruggeman, Richard and Cahn, Wiepke and de Haan, Lieuwe and Krabbendam, Lydia and Myin-Germeys, Inez and GROUP and Genetic Risk and Outcome in Psychosis (GROUP)
Nature, ISSN 0028-0836, 2009, Volume 460, Issue 7256, pp. 744 - 747
Schizophrenia is a complex disorder, caused by both genetic and environmental factors and their interactions. Research on pathogenesis has traditionally... 
NEUROGRANIN | POPULATION | DISEASES | MENTAL-RETARDATION | GENE | MEMORY | MULTIDISCIPLINARY SCIENCES | 1Q21.1 | SCAN | DELETIONS | GENOME-WIDE ASSOCIATION | Neurogranin - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Transcription Factor 4 | Major Histocompatibility Complex - genetics | Humans | Genotype | Chromosomes, Human, Pair 11 - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Chromosomes, Human, Pair 6 - genetics | Genome, Human - genetics | Schizophrenia - immunology | Schizophrenia - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors | Genetic Markers - genetics | Polymorphism, Single Nucleotide - genetics | Chromosomes, Human, Pair 18 - genetics | Major histocompatibility complex | Schizophrenia | Development and progression | Genetic aspects | Research | Single nucleotide polymorphisms | Health aspects | Risk factors | Celiac disease | Genetics | Disease | Autoimmune diseases | Mass spectrometry | Index Medicus
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5. Full Text Intravenous Use of Prescription Psychostimulants; A Comparison of the Pattern and Subjective Experience between Different Methylphenidate Preparations, Amphetamine and Cocaine
by Bjarnadottir, Gudrun D and Magnusson, Andres and Rafnar, Bjarni O and Sigurdsson, Engilbert and Steingrimsson, Steinn and Johannsson, Magnus and Bragadottir, Helena and Haraldsson, H. Magnus and Sahlgrenska akademin and Centre for Ethics, Law, and Mental Health and Göteborgs universitet and Gothenburg University and Centrum för etik, juridik och mental hälsa and Sahlgrenska Academy
European Addiction Research, ISSN 1022-6877, 08/2016, Volume 22, Issue 5, pp. 259 - 267
Background/Aims: Methylphenidate (MPH) has been the most commonly used intravenous (i.v.) substance in Iceland in recent years. In Iceland, MPH is available in... 
Research Report | ADHD | POPULATION | ORAL METHYLPHENIDATE | HUMAN BRAIN | MEDICATIONS | PSYCHIATRY | Intravenous use | DOPAMINE TRANSPORTERS | HUMANS | SUBSTANCE ABUSE | Injection rate | PHARMACOKINETICS | Euphoria | ABUSE | STIMULANTS | Methylphenidate | Psychostimulants | Iceland - epidemiology | Methylphenidate - administration & dosage | Cross-Sectional Studies | Humans | Amphetamine - administration & dosage | Male | Amphetamine - adverse effects | Methylphenidate - adverse effects | Delayed-Action Preparations - administration & dosage | Young Adult | Cocaine - administration & dosage | Administration, Intravenous | Central Nervous System Stimulants - adverse effects | Delayed-Action Preparations - adverse effects | Prescription Drug Misuse - psychology | Euphoria - drug effects | Drug Compounding | Adult | Female | Cocaine - adverse effects | Prescription Drug Misuse - adverse effects | Central Nervous System Stimulants - administration & dosage | Psychotropic drugs | Amphetamines | Drug abuse | Substance abuse treatment | Cocaine | Stimulants | Index Medicus | stimulants | abuse | dopamine transporters | oral methylphenidate | Klinisk medicin | Substance Abuse | population | Clinical Medicine | human brain | adhd | medications | pharmacokinetics | humans | Psychiatry
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6. Full Text Truncating mutations in RBM12 are associated with psychosis
by Steinberg, Stacy and Gudmundsdottir, Steinunn and Sveinbjornsson, Gardar and Suvisaari, Jaana and Paunio, Tiina and Torniainen-Holm, Minna and Frigge, Michael L and Jonsdottir, Gudrun A and Huttenlocher, Johanna and Arnarsdottir, Sunna and Ingimarsson, Oddur and Haraldsson, Magnus and Tyrfingsson, Thorarinn and Thorgeirsson, Thorgeir E and Kong, Augustine and Norddahl, Gudmundur L and Gudbjartsson, Daniel F and Sigurdsson, Engilbert and Stefansson, Hreinn and Stefansson, Kari
Nature Genetics, ISSN 1061-4036, 08/2017, Volume 49, Issue 8, pp. 1251 - 1254
Thus far, a handful of highly penetrant mutations conferring risk of psychosis have been discovered. Here we used whole-genome sequencing and long-range... 
CRITERIA | AUTISM | RARE | VARIANTS | DATABASE | FAMILIES | GENETICS & HEREDITY | HUMAN-DISEASES | SCHIZOPHRENIA | IDENTIFICATION | BURDEN | RNA-Binding Proteins - genetics | Psychotic Disorders - genetics | Humans | Family Health | Female | Male | Codon, Nonsense | Genome, Human | Sequence Analysis, DNA | Iceland | Physiological aspects | Genetic aspects | Research | Psychoses | Gene mutations | Risk factors | Psychosis | Studies | Mental disorders | Nonsense mutation | Schizophrenia | Bipolar disorder | Mutation | Ribonucleic acid--RNA | Siblings | Phasing | Index Medicus
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7. Full Text Assessment of turbulent viscous stress using ICOSA 4D Flow MRI for prediction of hemodynamic blood damage
by Ha, Hojin and Lantz, Jonas and Haraldsson, Henrik and Casas, Belen and Ziegler, Magnus and Karlsson, Matts and Saloner, David and Dyverfeldt, Petter and Ebbers, Tino and Avdelningen för kardiovaskulär medicin and Medicinska fakulteten and Region Östergötland and Mekanisk värmeteori och strömningslära and Linköpings universitet and Fysiologiska kliniken US and Tekniska fakulteten and Institutionen för ekonomisk och industriell utveckling and Institutionen för medicin och hälsa and Hjärt- och Medicincentrum and Centrum för medicinsk bildvetenskap och visualisering, CMIV
Scientific Reports, ISSN 2045-2322, 12/2016, Volume 6, Issue 1, pp. 39773 - 39773
Flow-induced blood damage plays an important role in determining the hemodynamic impact of abnormal blood flow, but quantifying of these effects, which are... 
VELOCITY | REYNOLDS SHEAR-STRESS | CELL DAMAGE | KINETIC-ENERGY | HEMOLYSIS | MULTIDISCIPLINARY SCIENCES | AORTIC-STENOSIS | MECHANICAL HEART-VALVE | SIMULATION | PHASE-CONTRAST MRI | STANDARD | Magnetic Resonance Angiography | Shear Strength | Constriction, Pathologic | Models, Cardiovascular | Humans | Blood Flow Velocity | Turbulence | Magnetic resonance imaging | Data processing | Shear stresses | Mechanical stimuli | Velocity | Blood flow | Index Medicus | Fluid Mechanics and Acoustics | Teknik och teknologier | Engineering and Technology | Mechanical Engineering | Strömningsmekanik och akustik | Maskinteknik
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8. Full Text TCT-107 Ticagelor is not superior to clopidogrel in patients with acute coronary syndrome – A report from SCAAR
by Redfors, Björn and Volz, Sebastian and Angeras, Oscar and Haraldsson, Inger and Ioanes, Dan and Odenstedt, Jacob and Petursson, Petur and Robertsson, Lotta and Stewart, Jason and Wahlin, Magnus and Albertsson, Per and Råmunddal, Truls and Omerovic, Elmir
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 68, Issue 18, pp. B43 - B43
  The following variables were used for adjustment of risk estimates: age; gender; hypertension; hyperlipidemia; smoking status; diabetes; calendar year;... 
Cardiovascular | Internal Medicine | Reports | Care and treatment | Cardiology | Coronary heart disease | Cardiac patients | Cardiovascular disease | Acute coronary syndromes | Health risk assessment | Stents | Thrombosis
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9. Full Text TCT-482 First generation drug-eluting stent is worse than contemporary bare metal stent after long-term follow-up: A report from SCAAR
by Volz, Sebastian and Dworeck, Christian and Angeras, Oscar and Haraldsson, Inger and Ioanes, Dan and Odenstedt, Jacob and Petursson, Petur and Robertsson, Lotta and Stewart, Jason and Wahlin, Magnus and Albertsson, Per and Råmunddal, Truls and Omerovic, Elmir
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 68, Issue 18, pp. B193 - B193
  To adjust for differences in patient's characteristics the following variables were used: age, gender, hypertension, hyperlipidemia, smoking status,... 
Cardiovascular | Internal Medicine | Reports | Cardiology | Statistics | Stent (Surgery) | Cardiovascular disease | Health risk assessment | Angina pectoris | Stents | Thrombosis
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10. Full Text Neutropenia and agranulocytosis during treatment of schizophrenia with clozapine versus other antipsychotics: An observational study in Iceland
by Ingimarsson, Oddur and MacCabe, James H and Haraldsson, Magnús and Jónsdóttir, Halldóra and Sigurdsson, Engilbert
BMC Psychiatry, ISSN 1471-244X, 12/2016, Volume 16, Issue 1, pp. 441 - 441
Background: Data on the haematological outcomes of patients who continue clozapine treatment following neutropenia are very rare as even mild neutropenia... 
Schizophrenia | Antipsychotics | Clozapine | Agranulocytosis | Neutropenia | PSYCHIATRY | RISK | DISCONTINUATION | Clozapine - therapeutic use | Agranulocytosis - chemically induced | Antipsychotic Agents - adverse effects | Humans | Middle Aged | Risk Factors | Hospitals, University | Male | Disease Progression | Iceland | Young Adult | Neutropenia - diagnosis | Antipsychotic Agents - therapeutic use | Adult | Female | Schizophrenia - drug therapy | Clozapine - adverse effects | Neutropenia - chemically induced | Electronic Health Records | Longitudinal Studies | Complications and side effects | Patient outcomes | Drug therapy | Risk factors | Granulocytopenia | Index Medicus
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11. Full Text Prognosis is similar for patients who undergo primary PCI during regular‐hours and off‐hours: A report from SCAAR
by Redfors, Björn and Dworeck, Christian and Angerås, Oskar and Haraldsson, Inger and Petursson, Petur and Odenstedt, Jacob and Ioanes, Dan and Völz, Sebastian and Hiller, Magnus and Fransson, Per and Stewart, Jason and Fryklund, Henrik and Albertsson, Per and Råmunddal, Truls and Omerovic, Elmir and Sahlgrenska akademin and Institute of Medicine, Department of Molecular and Clinical Medicine and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
Catheterization and Cardiovascular Interventions, ISSN 1522-1946, 06/2018, Volume 91, Issue 7, pp. 1240 - 1249
BackgroundTimely percutaneous coronary intervention (PCI) improves prognosis in ST-elevation myocardial infarction (STEMI). However, recent reports indicate... 
Swedish Coronary Angiography and Angioplasty Registry | percutaneous coronary intervention | coronary angiography | ST‐elevation myocardial infarction | ST-elevation myocardial infarction | HOSPITAL MORTALITY | CARDIAC & CARDIOVASCULAR SYSTEMS | ACUTE MYOCARDIAL-INFARCTION | TIME | OUTCOMES | ST-SEGMENT ELEVATION | PRIMARY ANGIOPLASTY | Percutaneous Coronary Intervention - mortality | Humans | Middle Aged | Male | Sweden | Time Factors | Health Services Accessibility | Aged, 80 and over | Female | Registries | Coronary Restenosis - etiology | Databases, Factual | Risk Assessment | Risk Factors | Treatment Outcome | After-Hours Care | Coronary Angiography | Outcome and Process Assessment (Health Care) | ST Elevation Myocardial Infarction - mortality | Shock, Cardiogenic - etiology | ST Elevation Myocardial Infarction - surgery | ST Elevation Myocardial Infarction - diagnostic imaging | Aged | Coronary Thrombosis - etiology | Percutaneous Coronary Intervention - adverse effects | Transluminal angioplasty | Shock | Medical research | Prognosis | Analysis | Cardiac patients | Medicine, Experimental | Risk factors | Myocardial infarction | Surgical implants | Statistical analysis | Angiography | Mortality | Health risks | Hazards | Regression analysis | Risk analysis | Patients | Thrombosis | Restenosis | Regression models | Statistical models | Working hours | Implants | Death | Infarction | Mathematical models | Thromboembolism | Cardiovascular diseases | Stents | Index Medicus | Kardiologi | Cardiac and Cardiovascular Systems
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12. Full Text Predicting the Effectiveness of Insulin Pump Therapy on Glycemic Control in Clinical Practice: A Retrospective Study of Patients with Type 1 Diabetes from 10 Outpatient Diabetes Clinics in Sweden over 5 Years
by Clements, Mark and Matuleviciene, Viktorija and Attvall, Stig and Ekelund, Magnus and Pivodic, Aldina and Dahlqvist, Sofia and Fahlén, Martin and Haraldsson, Börje and Lind, Marcus and Institute of Medicine, Department of Molecular and Clinical Medicine and Institute of Medicine and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Sahlgrenska akademin and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Institutionen för medicin
Diabetes Technology & Therapeutics, ISSN 1520-9156, 01/2015, Volume 17, Issue 1, pp. 21 - 28
Background: Multicenter long-term studies of predictors for the effectiveness of continuous subcutaneous insulin infusion (CSII) in clinical practice are... 
Original Articles | MULTIPLE DAILY INJECTIONS | INFUSION CSII | SEVERE HYPOGLYCEMIA | METAANALYSIS | BLOOD-GLUCOSE | ENDOCRINOLOGY & METABOLISM | COMPLICATIONS | QUALITY-OF-LIFE | MELLITUS | METABOLIC-CONTROL | ASSOCIATION | Body Mass Index | Glycated Hemoglobin A - analysis | Hypoglycemic Agents - therapeutic use | Humans | Middle Aged | Male | Treatment Outcome | Hyperglycemia - drug therapy | Diabetes Mellitus, Type 1 - drug therapy | Blood Glucose - drug effects | Sweden | Hyperglycemia - blood | Diabetes Mellitus, Type 1 - blood | Ambulatory Care Facilities | Adult | Female | Insulin Infusion Systems | Retrospective Studies | Insulin - therapeutic use | Usage | Type 1 diabetes | Patient outcomes | Insulin pumps | Dosage and administration | Drug therapy | Insulin | Ambulatory medical care | Methods | Confidence intervals | Body mass index | Clinical medicine | Diabetes | Hypoglycemia | Index Medicus | Allmän medicin | Family Medicine
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13. Full Text Loperamide abuse - constipation or heart attack?
by Gunnarsdottir, AK and Johannsson, M and Haraldsson, M and Bjarnadottir, GD
LAEKNABLADID, ISSN 0023-7213, 2018, Volume 104, Issue 12, pp. 543 - 547
Loperamide is a mu-opioid receptor agonist with antidiarrhoeal effects. It is considered to have a low abuse potential because of substantial first-pass... 
loperamide abuse | MEDICINE, GENERAL & INTERNAL | loperamide toxicity | loperamide misuse | loperamide
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