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Nature, ISSN 0028-0836, 03/2015, Volume 519, Issue 7541, pp. 57 - 62
Journal Article
Clinics in Colon and Rectal Surgery, ISSN 1531-0043, 05/2018, Volume 31, Issue 3, pp. 145 - 146
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2011, Volume 108, Issue 1, pp. 308 - 313
Journal Article
Journal Article
Clinics in Colon and Rectal Surgery, ISSN 1531-0043, 05/2018, Volume 31, Issue 3, pp. 147 - 152
Abstract Our understanding of the genetics of colorectal cancer has changed dramatically over recent years. Colorectal cancer can be classified in multiple... 
Review Article | hyper-mutated tumors | exome sequencing | colorectal cancer | intra-tumor heterogeneity | PATHWAYS | SURGERY | INSTABILITY | INTRATUMOR HETEROGENEITY | CLONAL EVOLUTION | PREVALENCE | COLON-CANCER | DNA | MUTATIONS | BLOCKADE | GASTROENTEROLOGY & HEPATOLOGY | PROGRESSION | Review
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e96023
Familial adenomatous polyposis (FAP) is often due to adenomatous polyposis coli (APC) gene germline mutations. Somatic APC defects are found in about 80% of... 
CANCER | MULTIDISCIPLINARY SCIENCES | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Antibiotics, Antineoplastic - pharmacology | Colonic Polyps - pathology | Epithelial Cells - drug effects | Humans | Colon - drug effects | Adenomatous Polyposis Coli - pathology | Intestinal Mucosa - drug effects | Intestinal Mucosa - cytology | Cell Differentiation | Wnt Signaling Pathway | Disease Models, Animal | Adenomatous Polyposis Coli Protein - genetics | SOX9 Transcription Factor - metabolism | Cell Line | Sirolimus - therapeutic use | Animals, Genetically Modified | Colon - pathology | Sirolimus - pharmacology | beta Catenin - metabolism | Disease Progression | Animals | Antibiotics, Antineoplastic - therapeutic use | Adenomatous Polyposis Coli - drug therapy | Colonic Polyps - drug therapy | Mice | Dysplasia | Care and treatment | Colorectal cancer | Development and progression | Rapamycin | Diagnosis | Drug therapy | Health aspects | TOR protein | Cell proliferation | Phosphorylation | Epithelial cells | Sox9 protein | Familial adenomatous polyposis | Tissue analysis | Kinases | Polyposis coli | Medical schools | Defects | Proteins | β-catenin | Endoscopes | Intestine | Quality | Rodents | Surgery | Animal tissues | Colon | Inhibition | Drug dosages | Adenomatous polyposis coli protein | Immunoglobulins | Goblet cells | Internal medicine | Gene expression | Epithelium | Insulin | Adenomatous polyposis coli | Mutation | Laboratory animals | Polyps | Tumors
Journal Article
Journal of Gastrointestinal Surgery, ISSN 1091-255X, 11/2019
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2018, Volume 24, Issue 9, pp. 2214 - 2224
Journal Article
Cell Metabolism, ISSN 1550-4131, 09/2016, Volume 24, Issue 3, pp. 447 - 461
Journal Article
Neoplasia, ISSN 1476-5586, 10/2019, Volume 21, Issue 10, pp. 1051 - 1062
Treatment of locally advanced rectal cancer includes chemotherapy, radiation, and surgery but patient responses to neoadjuvant treatment are variable. We have... 
SURVIVAL | ONCOLOGY | TRANSPORTERS | CHEMORADIATION | CHEMORADIOTHERAPY | MUTATIONS | TOTAL MESORECTAL EXCISION | CHEMOTHERAPY | REVEALS
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 45, pp. E9608 - E9617
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder and is a major risk factor for colorectal cancer (CRC). Hypoxia is a feature of IBD and... 
Inflammatory bowel disease | Mitochondrial iron | Hypoxia | STEAP4 | Colorectal cancer | hypoxia | colorectal cancer | MULTIDISCIPLINARY SCIENCES | IRON | mitochondrial iron | inflammatory bowel disease | DEFICIENCY | BOWEL-DISEASE | STAMP2 | COLITIS | EPITHELIUM | 6-TRANSMEMBRANE PROTEIN | PROGRESSION | CHELATION | Physiological aspects | Colon cancer | Methods | Proteomics | Biological Sciences | PNAS Plus
Journal Article
Surgery: Official Journal of the Society of University Surgeons, Central Surgical Association, and the American Association of Endocrine Surgeons, ISSN 0039-6060, 2016, Volume 160, Issue 5, pp. 1302 - 1308
Journal Article