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Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 1, pp. 75 - 87
Summary Background Poly(ADP-ribose) polymerase (PARP) inhibitors have activity in ovarian carcinomas with homologous recombination deficiency. Along with BRCA1... 
Hematology, Oncology and Palliative Medicine | POLY(ADP-RIBOSE) POLYMERASE | OLAPARIB | ONCOLOGY | HOMOLOGOUS RECOMBINATION DEFICIENCY | MUTANT-CELLS | DNA-REPAIR | CANCER | HETEROZYGOSITY | TUMORS | BREAST | GENOMIC LOSS | Prognosis | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Ovarian Neoplasms - pathology | Salvage Therapy | Neoplasm Recurrence, Local - drug therapy | Germ-Line Mutation - genetics | Neoplasm Recurrence, Local - pathology | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Peritoneal Neoplasms - drug therapy | Fallopian Tube Neoplasms - genetics | Female | Antineoplastic Agents - pharmacology | Poly(ADP-ribose) Polymerases - chemistry | Ovarian Neoplasms - drug therapy | Platinum - pharmacology | Fallopian Tube Neoplasms - drug therapy | Peritoneal Neoplasms - pathology | Neoplasms, Glandular and Epithelial - pathology | Fallopian Tube Neoplasms - pathology | Survival Rate | Poly(ADP-ribose) Polymerase Inhibitors - therapeutic use | BRCA1 Protein - genetics | International Agencies | Peritoneal Neoplasms - genetics | Neoplasms, Glandular and Epithelial - drug therapy | Carcinoma, Ovarian Epithelial | Indoles - therapeutic use | Neoplasm Recurrence, Local - genetics | Aged | Neoplasm Staging | BRCA2 Protein - genetics | Drug Resistance, Neoplasm - drug effects | Sugars | Monosaccharides | Ovarian cancer | Analysis | Carcinoma | Cancer
Journal Article
by Coleman, Robert L and Coleman, R L and Oza, Amit M and Oza, A M and Lorusso, D and Lorusso, Domenica and Aghajanian, C and Aghajanian, Carol and Oaknin, A and Oaknin, Ana and Dean, A and Dean, Andrew and Colombo, N and Colombo, Nicoletta and Weberpals, Johanne I and Weberpals, J I and Clamp, Andrew and Clamp, A and Scambia, Giovanni and Scambia, G and Leary, A and Leary, Alexandra and Holloway, Robert W and Holloway, R W and Gancedo, M Amenedo and Gancedo, Margarita Amenedo and Fong, Peter C and Fong, P C and Goh, Jeffrey C and Goh, J C and O'Malley, David M and O'Malley, D M and Armstrong, Deborah K and Armstrong, D K and Garcia-Donas, Jesus and Garcia-Donas, J and Swisher, E M and Swisher, Elizabeth M and Floquet, A and Floquet, Anne and Konecny, Gottfried E and Konecny, G E and McNeish, I A and McNeish, Iain A and Scott, C L and Scott, Clare L and Cameron, Terri and Maloney, Lara and Isaacson, Jeff and Goble, Sandra and Grace, Caroline and Harding, Thomas C and Raponi, Mitch and Sun, James and Lin, Kevin K and Giordano, Heidi and Ledermann, J A and Ledermann, Jonathan A and Buck, M and Friedlander, M L and Harnett, P and Kichenadasse, G and Denys, H and Dirix, L and Vergote, I and Elit, L and Ghatage, P and Plante, M and Provencher, D and Welch, S and Gladieff, L and Joly, F and Lortholary, A and Lotz, J and Medioni, J and Tredan, O and You, B and El-Balat, A and Hänle, C and Krabisch, P and Neunhöffer, T and Pölcher, M and Wimberger, P and Amit, A and Kovel, S and Leviov, M and Safra, T and Shapira-Frommer, R and Stemmer, S and Bologna, A and Pignata, S and Sabbatini, R F and Tamberi, S and Zamagni, C and O'Donnell, A and Herraez, A Casado and Guerra, E M and Palacio, I and Romero, I and Sanchez, A and ... and ARIEL3 Investigators and ARIEL3 investigators
The Lancet, ISSN 0140-6736, 10/2017, Volume 390, Issue 10106, pp. 1949 - 1961
Rucaparib, a poly(ADP-ribose) polymerase inhibitor, has anticancer activity in recurrent ovarian carcinoma harbouring a mutation or high percentage of... 
MEDICINE, GENERAL & INTERNAL | MULTICENTER | SOLID TUMORS | BEVACIZUMAB | OPEN-LABEL | CANCER | HETEROZYGOSITY | EPITHELIAL OVARIAN | CHEMOTHERAPY | Double-Blind Method | Follow-Up Studies | Risk Assessment | Humans | Middle Aged | Ovarian Neoplasms - pathology | Neoplasm Recurrence, Local - drug therapy | Survival Rate | Treatment Outcome | Ovarian Neoplasms - mortality | Neoplasm Recurrence, Local - mortality | Indoles - administration & dosage | Poly(ADP-ribose) Polymerase Inhibitors - administration & dosage | Neoplasm Recurrence, Local - pathology | Disease-Free Survival | Maintenance Chemotherapy - methods | Internationality | Ovarian Neoplasms - therapy | Female | Aged | Molecular Targeted Therapy - methods | Clinical trials | Care and treatment | Carcinoma | Drug therapy | Ovarian cancer | Cancer | Analysis | Chemotherapy | Ovarian carcinoma | Platinum | Biomarkers | Mutation | Cancer therapies | Tumors | Homologous recombination | Central nervous system | Poly(ADP-ribose) | Homology | Genomes | Fallopian tube | ADP | Anticancer properties | Metastases | Homologous recombination repair | Randomization | Pain | Motivation | Ribose | Hemoglobin | Alanine | Anemia | Poly(ADP-ribose) polymerase | Breast cancer | Patients | Survival | Heterozygosity | Abdomen | Polymerase | Inhibitors | Point mutation | Loss of heterozygosity | Antitumor activity | Aspartate aminotransferase | Peritoneum
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 69, Issue 2, pp. 176 - 185
Abstract Background Cangrelor, an intravenous, reversible P2Y12 antagonist, is approved for use in patients undergoing percutaneous coronary intervention... 
Cardiovascular | Internal Medicine | coronary artery disease | bleeding | antiplatelet therapy | outcomes | CARDIAC & CARDIOVASCULAR SYSTEMS | PRIMARY PCI | BIVALIRUDIN | IMPAIRED BIOAVAILABILITY | CHAMPION PHOENIX | CLOPIDOGREL | PLATELET INHIBITION | BLOOD-TRANSFUSION | ELEVATION MYOCARDIAL-INFARCTION | INSIGHTS | Prospective Studies | Ticlopidine - therapeutic use | Humans | Middle Aged | Male | Aspirin - adverse effects | Ticlopidine - adverse effects | Female | Aspirin - therapeutic use | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Double-Blind Method | Angioplasty, Balloon, Coronary - methods | Myocardial Ischemia - prevention & control | Treatment Outcome | Adenosine Monophosphate - therapeutic use | Ticlopidine - analogs & derivatives | Adenosine Monophosphate - adverse effects | Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors | Adenosine Monophosphate - analogs & derivatives | Clopidogrel | Aged | Hemorrhage - chemically induced | Infusions, Intravenous | Cohort Studies | Transluminal angioplasty | Continuing medical education | Cardiac patients | Medical care | Research institutes | Cardiology | Quality management | Heart attacks | Mortality | Thrombosis | Patients | Studies | Consortia | Ischemia | Coronary vessels | Bailouts | Intubation | Acute coronary syndromes | Stents | Drug dosages | Veins & arteries
Journal Article
Lancet Oncology, ISSN 1470-2045, 2012, Volume 13, Issue 5, pp. 509 - 517
Journal Article
Lancet Neurology, The, ISSN 1474-4422, 2017, Volume 16, Issue 9, pp. 701 - 711
Journal Article
by Guo, Shengwen and Lai, Chunren and Wu, Congling and Cen, Guiyin and Hariharan, A and Vijayakumari, Anupa A and Aarabi, Mohammad Hadi and Aballi, John and Nour, Abd Elazeim Abd Alla Mohamed and Abdelaziz, Mohammed and Abdolalizadeh, AmirHussein and Abdollahi, Mahsa and Abdul Aziz, Siti Aishah and Salam, Amritha Abdul and Abdulaziz, Nidhal and Abdulkadir, Ahmed and Abdullah, Sachal and Abdullah, Osama and Abrigo, Jill and Adachi, Noriaki and Adamson, Christopher and Adduru, Viraj and Adel, Tameem and Aderghal, Karim and Ades-Aron, Benjamin and Adeyosoye, Michael and Adlard, Paul and Srinivasa, Ag and Aganj, Iman and Agarwal, Ayush and Agarwal, Anupam and Agarwal, Anchit and Aguero, Cinthya and Aguiar, Pablo and Ahdidan, Jamila and Ahmad, Fayyaz and Ahmad, Rziwan and Ahmadi, Hessam and Ahmed, Nisar and Sid, Farid Ahmed and Ai, Edward and Ai, Qing and Aicha, Benyahia and Aitharaju, Sai and Aiyer, Aditya and Akkus, Zeynettin and Akodad, Sanae and Akramifard, Hamid and Aksman, Leon and Aktas, Said and Al-Janabi, Omar and Al-Nuaimi, Ali and AlAila, BahaaEddin and Alakwaa, Fadhl and Alam, Saruar and Alam, Fakhre and Alam Zaidi, Syed Farhan and Alan, Wiener and Alansari, Mukhtar and Alareqi, Ebrahim and Alberdi, Ane and Albsoul, Mohammad and Alderson, Thomas and Aleem, Hassan and Alex, Aishwarya and Alexander, Jacob and Alexopoulos, Panagiotis and Alfoldi, Jessica and Ali, Ayesha and Ali, Imdad and Alimoradian, Shirin and Aljabar, Paul and Aljabbouli, Hasan and Aljovic, Almir and Allen, Genevera and Alliende, Luz Maria and Almaguel, Frankis and Almgren, Hannes and Montes, Carmen Alonso and Alowaisheq, Tasneem and Alryalat, Saif Aldeen and Alsado, Majd and Alsaedi, Abdalrahman and Alshehri, Haifa and Altaf, Tooba and Altendahl, Marie and Altmann, Ane and Alvand, Ashkan and Filho, Manoel Alves and Alzubi, Raid and Amaral, Robert and Ambatipudi, Mythri and Amernath, Remya and Amlien, Inge and Amoroso, Nicola and Amri, Hakima and Anastasiou, Athanasios and Anbarasi, Jani and Anbarjafari, Gholamreza and Anderson, Wes and ... and Alzheimer's Dis Neuroimaging and Alzheimer's Disease Neuroimaging Initiative and The Alzheimer's Disease Neuroimaging Initiative
Frontiers in aging neuroscience, ISSN 1663-4365, 2017, Volume 9, Issue MAY, pp. 146 - 146
Journal Article