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Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7610, pp. 169 - 172
Ebola viruses (EBOVs) are responsible for repeated outbreaks of fatal infections, including the recent deadly epidemic in West Africa. There are currently no... 
SYSTEM | NIEMANN-PICK C1 | ENTRY | CHOLESTEROL | SMALL-MOLECULE INHIBITORS | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ANTIBODY | RECEPTOR | INFECTION | HIV-1 VIRION FUSION | Temperature | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Antiviral Agents - metabolism | Endosomes - metabolism | Protein Subunits - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Ebolavirus - drug effects | Ibuprofen - chemistry | Antiviral Agents - chemistry | Endosomes - drug effects | Viral Envelope Proteins - metabolism | Conserved Sequence | Marburgvirus - chemistry | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Binding Sites | Membrane Fusion - drug effects | Toremifene - metabolism | Toremifene - pharmacology | Cell Line | Antiviral Agents - pharmacology | Ibuprofen - pharmacology | Models, Molecular | Protein Structure, Quaternary - drug effects | Ibuprofen - metabolism | Virus Attachment - drug effects | Ebolavirus - chemistry | Viral Envelope Proteins - antagonists & inhibitors | Protein Stability - drug effects | Viral Envelope Proteins - chemistry | Hydrophobic and Hydrophilic Interactions | Protein Binding | Ligands | Protein Subunits - chemistry | Toremifene - chemistry | Ebola virus | Glycoproteins | Host-virus relationships | Observations | Health aspects | Drug interactions | Drug therapy | Binding sites | Viral infections | Crystal structure
Journal Article
Nature Immunology, ISSN 1529-2908, 05/2016, Volume 17, Issue 5, pp. 574 - 582
It has been proposed that the local segregation of kinases and the tyrosine phosphatase CD45 underpins T cell antigen receptor (TCR) triggering, but how such... 
DIMENSIONS | ACTIVATION | PROTEIN | RECOGNITION | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | ELECTRON-MICROSCOPY | RECEPTOR | IMMUNOLOGY | EXPRESSION | ANTIGEN | Protein Structure, Tertiary | Leukocyte Common Antigens - metabolism | Receptors, Antigen, T-Cell - metabolism | Jurkat Cells | Humans | Leukocyte Common Antigens - chemistry | Models, Molecular | Crystallography, X-Ray | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - immunology | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - metabolism | Microscopy, Electron | Leukocyte Common Antigens - immunology | Signal Transduction - immunology | Microscopy, Fluorescence - methods | T-Lymphocytes - metabolism | Time Factors | HEK293 Cells | ZAP-70 Protein-Tyrosine Kinase - immunology | ZAP-70 Protein-Tyrosine Kinase - metabolism | Receptors, Antigen, T-Cell - immunology | T-Lymphocytes - immunology | Cell receptors | Immune response | Cellular signal transduction | Genetic aspects | Properties | T cells | Health aspects | Biological Sciences | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) | Immunologi | Signal Transduction | T-Lymphocytes | ZAP-70 Protein-Tyrosine Kinase | Receptors, Antigen, T-Cell | Journal Article | Naturvetenskap | Immunology | Research Support, Non-U.S. Gov't | Biologi | Natural Sciences | Microscopy, Fluorescence | Leukocyte Common Antigens
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 04/2010, Volume 17, Issue 4, pp. 398 - 402
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 02/2011, Volume 18, Issue 2, pp. 198 - 204
Journal Article
Journal Article
Nature Methods, ISSN 1548-7091, 07/2017, Volume 14, Issue 8, pp. 805 - 810
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 08/2019, Volume 10, Issue 1, pp. 3691 - 12
Semaphorin ligands and their plexin receptors are one of the major cell guidance factors that trigger localised changes in the cytoskeleton. Binding of... 
REFINEMENT | SYSTEM | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | PLEXIN | RESOLUTION | OFF-TRACK | RECEPTOR | SECRETED SEMAPHORINS | EFFICIENT | Signaling | Receptors | Oligomerization | Insects | Semaphorins | Drosophila | Crosstalk | Cytoskeleton | Dimers | Tuning | Crystal structure
Journal Article