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Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 441 - 13
Developmental genes in metazoan genomes are surrounded by dense clusters of conserved noncoding elements (CNEs). CNEs exhibit unexplained extreme levels of... 
VERTEBRATE EVOLUTION | HUMAN GENOME | MULTIDISCIPLINARY SCIENCES | CHROMOSOME ORGANIZATION | ULTRACONSERVED ELEMENTS | KEY DEVELOPMENTAL GENES | HOX LOCI | CHROMATIN INTERACTIONS | REGULATORY ELEMENTS | ENHANCER-ADOPTION | MAMMALIAN GENOMES | Clusters | Genomes | Drosophila | Conservation | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2018, Volume 128, Issue 12, pp. 5620 - 5633
Journal Article
Philosophical Transactions: Biological Sciences, ISSN 0962-8436, 5/2015, Volume 370, Issue 1667, pp. 1 - 20150064
Journal Article
BMC Genomics, ISSN 1471-2164, 11/2015, Volume 16, Issue 1, pp. 963 - 963
Journal Article
Philosophical Transactions: Biological Sciences, ISSN 0962-8436, 12/2013, Volume 368, Issue 1632, pp. 1 - 12
Regions of several dozen to several hundred base pairs of extreme conservation have been found in non-coding regions in all metazoan genomes. The distribution... 
Vertebrates | Divergent evolution | Genomics | Genes | Humans | Evolution | Genetic loci | Genomes | Mammals | Genetic mutation
Journal Article
Journal Article
Development, ISSN 0950-1991, 05/2017, Volume 144, Issue 10, pp. e1.1 - e1.1
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 11092 - 13
During animal development, complex signals determine and organize a vast number of tissues using a very small number of signal transduction pathways. These... 
SEGMENT POLARITY GENE | SIGNALING PATHWAYS | STEM-CELLS | DROSOPHILA-MELANOGASTER | MULTIDISCIPLINARY SCIENCES | WINGLESS | PLANAR CELL POLARITY | CATENIN | MORPHOGEN GRADIENT | EXPRESSION | ARMADILLO | Gene silencing | Signal transduction | β-catenin | Wnt protein | Transduction | Cell size | Embryos
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 03/2019, Volume 26, Issue 12, pp. 3231 - 3245.e9
Regeneration of injured human heart muscle is limited and an unmet clinical need. There are no methods for the reproducible generation of clinical-quality stem... 
cardiovascular progenitors | laminin | regenerative cardiology | hESC-based cardiac muscle regeneration | PLURIPOTENT STEM-CELLS | HEART | TERM SELF-RENEWAL | REPAIR | REGENERATION | PURIFICATION | HUMAN FIBROBLASTS | CARDIOMYOCYTE DIFFERENTIATION | EXPRESSION | TRANSPLANTATION | CELL BIOLOGY
Journal Article
BMC genomics, 11/2015, Volume 16, p. 963
Precise quantitative and spatiotemporal control of gene expression is necessary to ensure proper cellular differentiation and the maintenance of homeostasis.... 
Computer Graphics | Animals | Thymocytes - metabolism | Humans | Molecular Sequence Annotation | K562 Cells | Databases, Genetic | Mice | Software | Genomics - methods | Chromatin - genetics
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 04/2018, Volume 77, Issue 4, pp. 596 - 601
Journal Article
RNA (New York, N.Y.), 09/2019
Differential gene isoform expression is a ubiquitous mechanism to enhance proteome diversity and maintain cell homeostasis. Mechanisms such as splicing that... 
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Journal Article