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Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 25, pp. 10672 - 10684
Journal Article
1975, 1. ed. en español. --, Sección de obras de historia, ISBN 8437500303, 300 p. --
Book
Journal of Biological Chemistry, ISSN 0021-9258, 07/2012, Volume 287, Issue 30, pp. 25086 - 25097
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2017, Volume 292, Issue 25, pp. 10672 - 10684
Cardiolipin (CL) is a dimeric phospholipid with critical roles in mitochondrial bioenergetics and signaling. Recently, inhibition of the release of oxidized... 
lipid oxidation | Signal Transduction | cardiolipin | lipid signaling | lipid metabolism | mass spectrometry (MS)
Journal Article
Neurology, ISSN 0028-3878, 04/2012, Volume 78, Issue 14, pp. 1038 - 1042
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2009, Volume 284, Issue 51, pp. 35632 - 35644
Genetic ablation of calcium-independent phospholipase A 2 γ (iPLA 2 γ) results in profound alterations in hippocampal phospholipid metabolism and mitochondrial... 
Metabolism and Bioenergetics
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2012, Volume 287, Issue 35, pp. 29837 - 29850
Background: The composition and regulation of the mitochondrial permeability transition pore (mPTP) are incompletely understood. Results: Calcium-induced mPTP... 
Cytochrome c | Reactive Oxygen Species (ROS) | Bioenergetics | Oxidative Stress | Fatty Acid | Acyl-CoA | Mitochondrial Swelling | Mitochondrial Permeability Transition | Calcium-independent PLA2gamma
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, ISSN 0363-6143, 04/2011, Volume 300, Issue 4, pp. C872 - C879
Sharma J, Turk J, Mancuso DJ, Sims HF, Gross RW, McHowat J. Activation of group VI phospholipase A(2) isoforms in cardiac endothelial cells. Am J Physiol Cell... 
ARACHIDONIC-ACID RELEASE | endothelium | PHYSIOLOGY | LIPID-METABOLISM | prostacyclin | GENETIC ABLATION | MECHANISM-BASED DISCRIMINATION | platelet-activating factor | CONTAINS | CELL BIOLOGY | INHIBITION | EXPRESS | ENZYMES | NITRIC-OXIDE | RECEPTORS | Heart | Physiological aspects | Phospholipases | Health aspects | Endothelium
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 04/2013, Volume 18, Issue 4, pp. 521 - 521
Recently, several genome-wide association studies (GWASs) have led to the discovery of nine new loci of genetic susceptibility in Alzheimer's disease (AD).... 
Life Sciences | Genetics | Santé publique et épidémiologie | Human genetics | Corrigendum
Journal Article
by Molina, Jean-Michel and Squires, Kathleen and Sax, Paul E and Cahn, Pedro and Lombaard, Johan and DeJesus, Edwin and Lai, Ming-Tain and Rodgers, Anthony and Lupinacci, Lisa and Kumar, Sushma and Sklar, Peter and Hanna, George J and Hwang, Carey and Martin, Elizabeth Anne and Hagins, Debbie P and Osiyemi, Olayemi O and Prelutsky, David James and Ramgopal, Moti N and Scarsella, Anthony John and Dretler, Robin and DeJesus, Edwin and Bettacchi, Christopher J and Sims, James and Clay, Patrick G and Bellos, Nicholaos C and Thompson, Melanie A and Montero, Jose and McDonald, Cheryl K and Creticos, Catherine and Shamblaw, David and Mogyoros, Miguel and Terrelonge, Antonio E and Valdes, Martin and Tashima, Karen T and Robbins, William J and Felizarta, Franco Antonio and Elion, Richard A and Slim, Jihad and Win, Sandra S and Lalla-Reddy, Sujata N and Ruane, Peter Jerome and Mills, Anthony and Cade, Jerry L and Dietz, Craig A and Rubin, David Scott and Mayer, Cynthia and Rondon, Juan Carlos and Cook, Paul P and Daar, Eric and Kumar, Princy N and Swindells, Susan and Castro, Jose Guillermo and Melendez-Rivera, Ivan and Morales-Ramirez, Javier O and Santiago, Lizette and Santana-Bagur, Jorge L and Martins, Marcelo and Cahn, Pedro Enrique and Lopardo, Gustavo D and Porteiro, Norma and Bloch, Mark Theo and Baker, David Alfred and Roth, Norman and Moore, Richard James and Finlayson, Robert James and McMahon, James and Rieger, Armin and Zoufaly, Alexander and Hartl, Sylvia and Zangerle, Robert and Smaill, Fiona and Walmsley, Sharon L and Conway, Brian and Rachlis, Anita and Smith, Graham H.R and Perez, Carlos and Afani, Alejandro and Campos, Maria Isabel and Chahin, Carolina Eugenia and Wolff Reyes, Marcelo and Gerstoft, Jan and Weis, Nina and Laursen, Alex Lund and Molina, Jean-Michel and Yazdanpanah, Yazdan and Cotte, Laurent and Raffi, Francois and Morlat, Philippe and Girard, Pierre-Marie and Katlama, Christine and Rockstroh, Juergen K and Arasteh, Keikawus and Esser, Stefan and Stoehr, Albrecht and Stellbrink, Hans-Juergen and Stoll, Matthias and Schuermann, Dirk and Faetkenheuer, Gerd and Bogner, Johannes and Lutz, Thomas and ... and DRIVE-FORWARD trial group and DRIVE-FORWARD Trial Grp
The Lancet HIV, ISSN 2352-3018, 01/2020, Volume 7, Issue 1, pp. e16 - e26
Doravirine is a novel, non-nucleoside reverse transcriptase inhibitor that has shown non-inferior efficacy to ritonavir-boosted darunavir, with a superior... 
REVERSE-TRANSCRIPTASE INHIBITOR | INFECTIOUS DISEASES | EFFICACY | SAFETY | VIROLOGICAL FAILURE | EFAVIRENZ | HIV-1-INFECTED PATIENTS | INFECTION | DOLUTEGRAVIR | RILPIVIRINE | IMMUNOLOGY | ETRAVIRINE
Journal Article
by Escott-Price, Valentina and Bellenguez, Céline and Wang, Li-San and Choi, Seung-Hoan and Harold, Denise and Jones, Lesley and Gerrish, Amy and Holmans, Peter and Vedernikov, Alexey and Richards, Alexander and DeStefano, Anita L and Lambert, Jean-Charles and Ibrahim-Verbaas, Carla A and Naj, Adam C and Sims, Rebecca and Jun, Gyungah and Bis, Joshua C and Beecham, Gary W and Grenier-Boley, Benjamin and Russo, Giancarlo and Thornton-Wells, Tricia A and Denning, Nicola and Smith, Albert V and Chouraki, Vincent and Thomas, Charlene and Ikram, M. Arfan and Zelenika, Diana and Vardarajan, Badri N and Kamatani, Yoichiro and Lin, Chiao-Feng and Schmidt, Helena and Kunkle, Brian and Dunstan, Melanie L and Vronskaya, Maria and Johnson, Andrew D and Ruiz, Agustin and Bihoreau, Marie-Thérèse and Reitz, Christiane and Pasquier, Florence and Hollingworth, Paul and Hanon, Olivier and Fitzpatrick, Annette L and Buxbaum, Joseph D and Campion, Dominique and Crane, Paul K and Baldwin, Clinton and Becker, Tim and Gudnason, Vilmundur and Cruchaga, Carlos and Craig, David and Amin, Najaf and Berr, Claudine and Lopez, Oscar L and De Jager, Philip Lawrence and Deramecourt, Vincent and Johnston, Janet A and Evans, Denis and Lovestone, Simon and Letenneur, Luc and Hernández, Isabel and Rubinsztein, David C and Eiriksdottir, Gudny and Goate, Alison M and Sleegers, Kristel and Fiévet, Nathalie and Huentelman, Matthew J and Gill, Michael and Brown, Kristelle and Kamboh, M. Ilyas and Keller, Lina and Barberger-Gateau, Pascale and McGuinness, Bernadette and Larson, Eric B and Myers, Amanda J and Dufouil, Carole and Todd, Stephen and Wallon, David and Love, Seth and Rogaeva, Ekaterina and Gallacher, John and St George-Hyslop, Peter and Clarimon, Jordi and Lleo, Alberto and Bayer, Anthony and Tsuang, Debby W and Yu, Lei and Tsolaki, Magda and Bossù, Paola and Spalletta, Gianfranco and Proitsi, Petra and Collinge, John and Sorbi, Sandro and Sanchez Garcia, Florentino and Fox, Nick C and Hardy, John and Naranjo, Maria Candida Deniz and Bosco, Paolo and Clarke, Robert and Brayne, Carol and Galimberti, Daniela and ...
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 6, p. e94661
Background: Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified,... 
Disease susceptibility--Genetic aspects | Pathology | Genetics | Genomics--Data processing | Alzheimer's disease--Genetic aspects | Medical sciences
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2007, Volume 282, Issue 48, pp. 34611 - 34622
Previously, we identified a novel calcium-independent phospholipase, designated calcium-independent phospholipase A 2 γ (iPLA 2 γ ), which possesses dual... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2010, Volume 285, Issue 47, pp. 36495 - 36510
Phospholipases are critical enzyme mediators participating in many aspects of cellular function through modulating the generation of lipid 2nd messengers,... 
Adipose Tissue Metabolism | Skeletal Muscle Metabolism | Bioenergetics | Metabolic Syndrome | Respirometry | Lipidomics | Diabetes
Journal Article
Circulation, ISSN 0009-7322, 03/1999, Volume 99, Issue 10, pp. 1337 - 1343
Background-Genetic defects are being increasingly recognized in the etiology of primary cardiomyopathy (CM). Very-long-chain acyl-CoA dehydrogenase (VLCAD)... 
Genetics | Death, sudden | Metabolism | Cardiomyopathy | Fatty acids | CARDIAC & CARDIOVASCULAR SYSTEMS | fatty acids | death, sudden | ACID OXIDATION DISORDERS | DILATED CARDIOMYOPATHY | IDENTIFICATION | genetics | LIVER | MUTATION | DISEASE | PERIPHERAL VASCULAR DISEASE | metabolism | cardiomyopathy | HEMATOLOGY
Journal Article