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Journal of Molecular Biology, ISSN 0022-2836, 2019
Ribosomes are central to the life of a cell, as they translate the genetic code into the amino acid language of proteins. Moreover, ribosomal abundance within... 
ribosome | degradation | autophagy | ubiquitin
Journal Article
Nature, ISSN 0028-0836, 03/2018, Volume 555, Issue 7697, pp. 449 - 451
Low-complexity protein aggregates are a hallmark of neurodegeneration. High-resolution snapshots of the structure of one such aggregate offer an unprecedented... 
C9ORF72 | MULTIDISCIPLINARY SCIENCES | DIPEPTIDE REPEAT | Proteins | Gene mutations | Physiological aspects | Nervous system | Genetic aspects | Degeneration | Health aspects | Risk factors | Nervous system diseases | Nucleotides | Glycine | Disease | Microscopy | Neurodegeneration | Neurons | Amyotrophic lateral sclerosis | Mutation | Stalling
Journal Article
Molecular Cell, ISSN 1097-2765, 06/2019, Volume 74, Issue 5, pp. 891 - 908.e10
Cells respond to nutrient stress by trafficking cytosolic contents to lysosomes for degradation via macroautophagy. The endoplasmic reticulum (ER) serves as an... 
TEX264 | ER-phagy | selective autophagy | Proteins | Medical colleges | Analysis | Cells
Journal Article
Nature cell biology, ISSN 1465-7392, 2/2018, Volume 20, Issue 2, pp. 135 - 143
Ribosomes are abundant cellular machines 1 , 2 regulated by assembly, supernumerary subunit turnover, and nascent chain quality control mechanisms 1 – 5 .... 
Journal Article
Nature, ISSN 0028-0836, 06/2014, Volume 510, Issue 7505, p. 347
Journal Article
Nature, ISSN 0028-0836, 06/2014, Volume 510, Issue 7505, p. 347
  Although a mitophagy signalling pathway comprised of two enzymes, PINK1 and parkin, has been identified, it is not clear what factors inhibit the pathway. In... 
Proteins | Enzymes | Mitochondria | Dopamine | Parkinsons disease | Cells | Defects
Journal Article
Nature, ISSN 0028-0836, 06/2014, Volume 510, Issue 7505, p. 347
Journal Article
Nature, ISSN 0028-0836, 06/2014, Volume 510, Issue 7505, p. 347
Journal Article
Nature, ISSN 0028-0836, 06/2014, Volume 510, Issue 7505, p. 347
Journal Article
Nature, ISSN 0028-0836, 06/2014, Volume 510, Issue 7505, pp. 347 - 348
Journal Article
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 05/2009, Volume 10, Issue 5, pp. 319 - 331
Journal Article
Molecular Cell, ISSN 1097-2765, 12/2007, Volume 28, Issue 5, pp. 739 - 745
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2014, Volume 53, Issue 2, pp. 165 - 166
In this issue, describe how microtubules and the RAN GTPase/importin-β system collaborate to control timing of HURP action and its turnover via the anaphase... 
COMPLEX | MICROTUBULES | KINETOCHORE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUSAP | HURP | CHROMOSOMES | CELL BIOLOGY | Humans | Spindle Apparatus - metabolism | Microtubules - physiology | Cells
Journal Article
Molecular Cell, ISSN 1097-2765, 2011, Volume 44, Issue 2, pp. 325 - 340
Despite the diverse biological pathways known to be regulated by ubiquitylation, global identification of substrates that are targeted for ubiquitylation has... 
CELLS | PHOSPHORYLATION | ACETYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TARGETS | NEDD8 | CHAINS | IDENTIFICATION | PROTEINS | REVEALS | CELL BIOLOGY | Glycylglycine - genetics | Lysine - genetics | Ubiquitination | HCT116 Cells | Humans | Cells, Cultured | Proteomics | Ubiquitin - metabolism | Cullin Proteins - metabolism | Proteome - metabolism | Ubiquitin | Monoclonal antibodies | Trypsin | Ligases | Lysine | Analysis
Journal Article
Molecular Cell, ISSN 1097-2765, 05/2015, Volume 58, Issue 4, pp. 660 - 676
Journal Article