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science & technology (15) 15
animals (12) 12
humans (12) 12
life sciences & biomedicine (10) 10
mice (7) 7
molecular structure (7) 7
cancer (6) 6
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ligands (4) 4
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plasmodium falciparum - drug effects (4) 4
radiology, nuclear medicine & medical imaging (4) 4
amines - chemistry (3) 3
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atp-binding cassette, sub-family b, member 1 - metabolism (3) 3
dose-response relationship, drug (3) 3
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imaging (3) 3
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spect (3) 3
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biological transport (2) 2
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blood-brain barrier (2) 2
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cell line (2) 2
cell survival - drug effects (2) 2
chemistry, medicinal (2) 2
chemotherapy (2) 2
chloroquine - pharmacology (2) 2
crystallography, x-ray (2) 2
drug resistance (2) 2
fluorescence (2) 2
gallium radioisotopes - chemistry (2) 2
guanine - analogs & derivatives (2) 2
hela cells (2) 2
isotopes (2) 2
luminescence (2) 2
medicine (2) 2
metalloprobes (2) 2
microscopy, fluorescence - methods (2) 2
molecular imaging - methods (2) 2
multidisciplinary sciences (2) 2
nanoparticles (2) 2
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p-glycoprotein (2) 2
parasitic sensitivity tests (2) 2
peptides (2) 2
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zinc - chemistry (2) 2
abcb1 expression (1) 1
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alzheimer’s disease (1) 1
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1. Full Text The neurofibromatosis type 1 tumor suppressor controls cell growth by regulating signal transducer and activator of transcription-3 activity in vitro and in vivo
by Banerjee, Sutapa and Byrd, Jonathan N and Gianino, Scott M and Harpstrite, Scott E and Rodriguez, Fausto J and Tuskan, Robert G and Reilly, Karlyne M and Piwnica-Worms, David R and Gutmann, David H
Cancer research (Chicago, Ill.), ISSN 0008-5472, 02/2010, Volume 70, Issue 4, pp. 1356 - 1366
Life Sciences & Biomedicine | Oncology | Science & Technology | Neurology | Tumors of the nervous system. Phacomatoses | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Antineoplastic agents | Tumors | Triterpenes - pharmacology | Humans | Male | Intracellular Signaling Peptides and Proteins - metabolism | STAT3 Transcription Factor - physiology | Genes, Tumor Suppressor - physiology | Chromones - pharmacology | Protein-Serine-Threonine Kinases - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Animals, Newborn | Neurofibromin 1 - physiology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Mice, Transgenic | Signal Transduction - genetics | Gene Expression Regulation - drug effects | Xenograft Model Antitumor Assays | Animals | Signal Transduction - drug effects | Mice, Nude | Cell Proliferation - drug effects | Mice | TOR Serine-Threonine Kinases | STAT3 Transcription Factor - antagonists & inhibitors | Neurofibromin 1 - genetics | Index Medicus
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2. Full Text Interrogation of multidrug resistance (MDR1) P-glycoprotein (ABCB1) expression in human pancreatic carcinoma cells: correlation of 99mTc-Sestamibi uptake with western blot analysis
by Harpstrite, Scott E and Gu, Hannah and Natarajan, Radhika and Sharma, Vijay
Nuclear medicine communications, ISSN 0143-3636, 10/2014, Volume 35, Issue 10, pp. 1067 - 1070
pancreatic carcinoma | imaging | ABCB1 expression | Pancreatic Neoplasms - metabolism | Radiopharmaceuticals - pharmacokinetics | ATP Binding Cassette Transporter, Sub-Family B - biosynthesis | Humans | Radionuclide Imaging | Cell Line, Tumor | Technetium Tc 99m Sestamibi - pharmacokinetics | Blotting, Western | Pancreatic Neoplasms - diagnostic imaging
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3. Full Text (67/68)Galmydar: A metalloprobe for monitoring breast cancer resistance protein (BCRP)-mediated functional transport activity
by Sivapackiam, Jothilingam and Harpstrite, Scott E and Prior, Julie L and Mattingly, Stephen and Sharma, Vijay
Nuclear medicine and biology, ISSN 0969-8051, 03/2016, Volume 43, Issue 3, pp. 191 - 197
Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Optical Imaging | Radioactive Tracers | ATP Binding Cassette Transporter, Subfamily G, Member 2 - metabolism | Humans | Fluorescent Dyes - metabolism | Coordination Complexes - metabolism | Male | Tomography, X-Ray Computed | Positron-Emission Tomography | Neoplasm Proteins - metabolism | Animals | Biological Transport | Organometallic Compounds - metabolism | HEK293 Cells | Gallium Radioisotopes | Mice | Index Medicus
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4. Full Text 67/68Galmydar: A metalloprobe for monitoring breast cancer resistance protein (BCRP)-mediated functional transport activity
by Sivapackiam, Jothilingam and Harpstrite, Scott E and Prior, Julie L and Mattingly, Stephen and Sharma, Vijay
Nuclear medicine and biology, ISSN 0969-8051, 03/2016, Volume 43, Issue 3, pp. 191 - 197
BCRP | Gallium | Metalloprobe
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5. Full Text 67Ga-metalloprobes: monitoring the impact of geometrical isomers on accumulation profiles in rat cardiomyoblasts and human breast carcinoma cellsElectronic supplementary information (ESI) available: Experimental method. CCDC 1496192. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6md00474a
by Sivapackiam, Jothilingam and Harpstrite, Scott E and Rath, Nigam P and Sharma, Vijay
ISSN 2040-2503, 1/2017, Volume 8, Issue 1, pp. 158 - 161
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6. Full Text Metalloprobes: Fluorescence imaging of multidrug resistance -mediated functional transport activity in cellulo
by Sundaram, G.S.M and Sharma, Monica and Kaganov, Daniel and Cho, Junsang and Harpstrite, Scott E and Sharma, Vijay
Journal of inorganic biochemistry, ISSN 0162-0134, 06/2016, Volume 159, p. 159
Fluorescence | Cytokinins | Drug resistance in microorganisms | Torture | Ethylenediamines
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7. Full Text sup.67/68Galmydar: A metalloprobe for monitoring breast cancer resistance protein -mediated functional transport activity
by Sivapackiam, Jothilingam and Harpstrite, Scott E and Prior, Julie L and Mattingly, Stephen and Sharma, Vijay
Nuclear medicine and biology, ISSN 0969-8051, 03/2016, Volume 43, Issue 3, p. 191
Chemotherapy | Breast cancer | Cancer
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8. Full Text Utilizing the Multiradionuclide Resolving Power of SPECT and Dual Radiolabeled Single Molecules to Assess Treatment Response of Tumors
by Xu, Baogang and Shokeen, Monica and Sudlow, Gail P and Harpstrite, Scott E and Liang, Kexian and Cheney, Philip P and Edwards, W Barry and Sharma, Vijay and Laforest, Richard and Akers, Walter J and Achilefu, Samuel
Molecular imaging and biology, ISSN 1536-1632, 10/2015, Volume 17, Issue 5, pp. 671 - 679
Radionuclide | Cleavable peptide | Medicine & Public Health | Caspase | Programmed cell death | Imaging / Radiology | SPECT | Cancer | Apoptosis | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Tomography, Emission-Computed, Single-Photon - methods | Radiopharmaceuticals - chemistry | Radiopharmaceuticals - pharmacokinetics | Apoptosis - drug effects | Humans | Molecular Imaging - methods | Antineoplastic Agents - therapeutic use | Neoplasms - diagnostic imaging | Neoplasms - drug therapy | Hydrolysis | Tissue Distribution | Animals | Caspase 3 | Cell Line, Tumor | Female | Antineoplastic Agents - pharmacology | Mice | Mice, Inbred BALB C | Neoplasms - pathology | Chemotherapy | Peptides | SPECT imaging | Genetic engineering | Drug therapy | Tumors | Index Medicus
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9. Full Text F4-01-01: PLASMA TEST FOR AMYLOID RISK SCREENING: THE C2 N SPONSORED PARIS ADD-ON STUDY TO IDEAS
by Yarasheski, Kevin E and West, Tim and Verghese, Philip B and Hu, Yan and Kirmess, Kris and Meyer, Matthew and Smith, Erin and Harpstrite, Scott and Holubasch, Mary and Knapik, Stephanie and Harlan, Antoinette and Fogelman, Ilana and Braunstein, Joel B
Alzheimer's & dementia, ISSN 1552-5260, 07/2019, Volume 15, pp. P1216 - P1216
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10. Full Text Metalloprobes: Fluorescence imaging of multidrug resistance (MDR1) P-Glycoprotein (Pgp)-mediated functional transport activity in cellulo
by Sundaram, G.S.M and Sharma, Monica and Kaganov, Daniel and Cho, Junsang and Harpstrite, Scott E and Sharma, Vijay
Journal of inorganic biochemistry, ISSN 0162-0134, 06/2016, Volume 159, pp. 159 - 164
Biochemistry & Molecular Biology | Physical Sciences | Chemistry, Inorganic & Nuclear | Chemistry | Life Sciences & Biomedicine | Science & Technology | Fluorescent Dyes - chemistry | Gallium - pharmacology | Gallium - chemistry | Microscopy, Fluorescence - methods | Biological Transport, Active - physiology | Humans | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Cell Line, Tumor | Fluorescent Dyes - pharmacology | Zinc - pharmacology | Zinc - chemistry | Index Medicus
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11. Synthesis, characterization, and antimalarial activity of novel Schiff-base-phenol and naphthalene-amine ligands
by Harpstrite, Scott E and Collins, Silvia D and Oksman, Ana and Goldberg, Daniel E and Sharma, Vijay
Medicinal chemistry (Shp-sariqah, United Arab Emirates), ISSN 1573-4064, 2008, Volume 4, Issue 4, pp. 392 - 395
Antimalarials | P. falciparum | Naphthalene-amine | Schiff-base phenol | Chloroquine-resistance | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Amines - chemistry | Naphthalenes - chemistry | Phenol - chemical synthesis | Amines - chemical synthesis | Phenol - pharmacology | Plasmodium falciparum - drug effects | Antimalarials - pharmacology | Animals | Schiff Bases - chemistry | Antimalarials - chemistry | Phenol - chemistry | Ligands | Molecular Structure | Amines - pharmacology | Antimalarials - chemical synthesis
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12. Full Text A Generator-produced gallium-68 radiopharmaceutical for PET imaging of myocardial perfusion
by Sharma, Vijay and Sivapackiam, Jothilingam and Harpstrite, Scott E and Prior, Julie L and Gu, Hannah and Rath, Nigam P and Piwnica-Worms, David
PloS one, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, pp. e109361 - e109361
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Line | Radiopharmaceuticals - chemistry | Radiopharmaceuticals - pharmacokinetics | Ethylenediamines - chemistry | Humans | Ethylenediamines - pharmacokinetics | Organometallic Compounds - pharmacokinetics | Rats | Male | Gallium Radioisotopes - chemistry | Positron-Emission Tomography - methods | Radiopharmaceuticals - chemical synthesis | Rats, Sprague-Dawley | Ethylenediamines - chemical synthesis | Myocardial Perfusion Imaging - methods | Animals | MCF-7 Cells | Organometallic Compounds - chemical synthesis | Organometallic Compounds - chemistry | Radionuclide Generators | Mice | Gallium | Medical imaging | Ethanol | Supply chains | Positron emission | Radioisotopes | Technetium isotopes | Generators | Technetium | Molybdenum | Medicine | Lipophilic | Onsite | Blood-brain barrier | Perfusion | Imaging | Radiochemistry | Tomography | Germanium | Isotopes | Worms | Cancer | Pharmaceuticals | Index Medicus
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13. Full Text A New Nucleoside Analogue with Potent Activity against Mutant sr39 Herpes Simplex Virus-1 (HSV-1) Thymidine Kinase (TK)
by Sundaram, G. S. M and Harpstrite, Scott E and Kao, Jeff Lung-Fa and Collins, Silvia D and Sharma, Vijay
Organic letters, ISSN 1523-7060, 07/2012, Volume 14, Issue 14, pp. 3568 - 3571
Nucleosides - chemical synthesis | Guanine - analogs & derivatives | Humans | Antiviral Agents - metabolism | Viral Proteins - metabolism | Guanine - metabolism | Acyclovir - chemistry | Antiviral Agents - chemistry | Guanine - pharmacology | Nucleosides - pharmacology | Guanine - chemistry | Molecular Structure | Radiopharmaceuticals | Binding Sites | Herpesvirus 1, Human - chemistry | Antiviral Agents - pharmacology | Nucleosides - chemistry | Herpesvirus 1, Human - metabolism | Thymidine Kinase - chemistry | Viral Proteins - chemistry | Acyclovir - pharmacology | Viral Proteins - genetics | Positron-Emission Tomography - methods | Herpesvirus 1, Human - drug effects | Herpesvirus 1, Human - enzymology | Thymidine Kinase - metabolism | Cell Line, Tumor | HeLa Cells | Index Medicus
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14. Synthesis, characterization, and molecular structure of a novel zinc (II) complex: Assessment of impact of MDR1Pgp expression on its cytotoxic activity
by Harpstrite, Scott E and Prior, Julie L and Sivapackiam, Jothilingam and Collins, Silvia D and Rath, Nigam P and Sharma, Vijay
Medicinal chemistry (Shp-sariqah, United Arab Emirates), ISSN 1573-4064, 2010, Volume 6, Issue 4, pp. 191 - 199
P-glycoprotein | Blood-Brain Barrier (BBB) | Metalloprobes | Zinc(II) complex | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Cell Survival - drug effects | Antineoplastic Agents - chemical synthesis | Drug Resistance, Multiple - drug effects | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Models, Molecular | Crystallography, X-Ray | Structure-Activity Relationship | ATP-Binding Cassette, Sub-Family B, Member 1 - biosynthesis | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Antineoplastic Agents - chemistry | Zinc - chemistry | Dose-Response Relationship, Drug | Organometallic Compounds - chemical synthesis | Organometallic Compounds - chemistry | Antineoplastic Agents - pharmacology | Molecular Structure | Tumor Cells, Cultured | Organometallic Compounds - pharmacology | Drug Resistance, Neoplasm - drug effects
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15. Full Text Second-Generation Triple Reporter for Bioluminescence, Micro–Positron Emission Tomography, and Fluorescence Imaging
by Kesarwala, Aparna H and Prior, Julie L and Sun, Jinwu and Harpstrite, Scott E and Sharma, Vijay and Piwnica-Worms, David
Molecular imaging, ISSN 1535-3508, 10/2006, Volume 5, Issue 4, pp. 465 - 474
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Biochemical Research Methods | Science & Technology | Cell Line | Flow Cytometry - methods | Thymidine Kinase - genetics | Acyclovir - analogs & derivatives | Guanine - analogs & derivatives | Guanine - pharmacokinetics | Humans | Simplexvirus - genetics | Luminescence | Positron-Emission Tomography - methods | Simplexvirus - enzymology | Acyclovir - pharmacokinetics | Luminescent Agents | Animals | Transfection | Microscopy, Fluorescence - methods | Recombinant Fusion Proteins - pharmacokinetics | Recombinant Fusion Proteins - genetics | Luciferases, Firefly - genetics | Mice | HeLa Cells | Genes, Reporter | Index Medicus
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16. Full Text Synthesis, molecular structure, and validation of metalloprobes for assessment of MDR1 P-glycoprotein-mediated functional transportCCDC reference number 764605. For crystallographic data in CIF or other electronic format see DOI: 10.1039/c002361b
by Sivapackiam, Jothilingam and Harpstrite, Scott E and Prior, Julie L and Gu, Hannah and Rath, Nigam P and Sharma, Vijay
ISSN 1477-9226, 6/2010, Volume 39, Issue 25, pp. 5842 - 585
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17. Full Text Metalloprobes: Synthesis, characterization, and potency of a novel gallium(III) complex in human epidermal carcinoma cells
by Harpstrite, Scott E and Prior, Julie L and Rath, Nigam P and Sharma, Vijay
Journal of inorganic biochemistry, ISSN 0162-0134, 2007, Volume 101, Issue 10, pp. 1347 - 1353
MDR1 P-glycoprotein | Cytotoxicity | Metalloprobes | Gallium(III) complex | Biochemistry & Molecular Biology | Physical Sciences | Chemistry, Inorganic & Nuclear | Chemistry | Life Sciences & Biomedicine | Science & Technology | Molecular Probes | Skin Neoplasms - pathology | Gallium - pharmacology | Gallium - chemistry | Magnetic Resonance Spectroscopy | Metals - chemistry | Humans | Skin Neoplasms - chemistry | Cell Line, Tumor | Models, Molecular | ATP-Binding Cassette, Sub-Family B, Member 1 - physiology | Microbiological synthesis | Development and progression | Carcinoma | Chemical properties | Cancer | Index Medicus | gallium(III) complex | cytotoxicity
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