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1. Full Text DNA methylation-based classification of central nervous system tumours
by Capper, David and Jones, David T. W and Sill, Martin and Hovestadt, Volker and Schrimpf, Daniel and Sturm, Dominik and Koelsche, Christian and Sahm, Felix and Chavez, Lukas and Reuss, David E and Kratz, Annekathrin and Wefers, Annika K and Huang, Kristin and Pajtler, Kristian W and Schweizer, Leonille and Stichel, Damian and Olar, Aiana and Engel, Nils W and Lindenberg, Kerstin and Harter, Patrick N and Braczynski, Anne K and Plate, Karl H and Dohmen, Hildegard and Garvalov, Boyan K and Coras, Roland and Hölsken, Annett and Hewer, Ekkehard and Bewerunge-Hudler, Melanie and Schick, Matthias and Fischer, Roger and Beschorner, Rudi and Schittenhelm, Jens and Staszewski, Ori and Wani, Khalida and Varlet, Pascale and Pages, Melanie and Temming, Petra and Lohmann, Dietmar and Selt, Florian and Witt, Henik and Milde, Till and Witt, Olaf and Aronica, Eleonora and Giangaspero, Felice and Rushing, Elisabeth and Scheurlen, Wolfram and Geisenberger, Christoph and Roiguez, Fausto J and Becker, Albert and Preusser, Matthias and Haberler, Christine and Bjerkvig, Rolf and Cryan, Jane and Farrell, Michael and Deckert, Martina and Hench, J. rgen and Frank, Stephan and Serrano, Jonathan and Kannan, Kasthuri and Tsirigos, Aristotelis and Brück, Wolfgang and Hofer, Silvia and Brehmer, Stefanie and Seiz-Rosenhagen, Marcel and Hänggi, Daniel and Hans, Volkmar and Rozsnoki, Stephanie and Hansford, Jordan R and Kohlhof, Patricia and Kristensen, Bjarne W and Lechner, Matt and Lopes, Beatriz and Mawrin, Christian and Ketter, Ralf and Kulozik, Aneas and Khatib, Ziad and Heppner, Frank and Koch, Arend and Jouvet, Anne and Keohane, Catherine and Mühleisen, Helmut and Mueller, Wolf and Pohl, Ute and Prinz, Marco and Benner, Axel and Zapatka, Marc and Gottardo, Nicholas G and ever, Pablo Hernáiz and Kramm, Christof M and Müller, Hermann L and Rutkowski, Stefan and von Hoff, Katja and Frühwald, Michael C and Gnekow, Astrid and Fleischhack, Guun and Tippelt, Stephan and Calaminus, Gabriele and Monoranu, Camelia-Maria and Perry, Arie and Jones, Chris and ...
Nature (London), ISSN 0028-0836, 2018, Volume 555, Issue 7697, pp. 469 - 474
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Central Nervous System Neoplasms - classification | Reproducibility of Results | Central Nervous System Neoplasms - genetics | Humans | Middle Aged | Child, Preschool | Infant | Male | Unsupervised Machine Learning | Young Adult | Central Nervous System Neoplasms - pathology | DNA Methylation | Adolescent | Aged, 80 and over | Adult | Female | Aged | Central Nervous System Neoplasms - diagnosis | Child | Cohort Studies | Genetic aspects | Nucleotide sequencing | Diagnosis | Methylation | Observations | Methods | DNA sequencing | Tumors | Cancer | Analysis | DNA | Machine learning | Central nervous system | Classifiers | Brain cancer | Standardization | Clinical trials | Probability | Data processing | Nervous system | Genomes | Gene expression | Generalized linear models | Learning algorithms | Classification | Diagnostic software | DNA methylation | Diagnostic systems | Bioinformatics | Deoxyribonucleic acid--DNA | Index Medicus
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2. Full Text The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury
by Enzmann, Gaby and Enzmann, Gaby and Mysiorek, Caroline and Mysiorek, Caroline and Gorina, Roser and Gorina, Roser and Cheng, Yu-Jung and Cheng, Yu-Jung and Ghavampour, Sharang and Ghavampour, Sharang and Hannocks, Melanie-Jane and Hannocks, Melanie-Jane and Prinz, Vincent and Prinz, Vincent and Dirnagl, Ulrich and Dirnagl, Ulrich and Endres, Matthias and Endres, Matthias and Prinz, Marco and Prinz, Marco and Beschorner, Rudi and Beschorner, Rudi and Harter, Patrick N and Harter, Patrick N and Mittelbronn, Michel and Mittelbronn, Michel and Engelhardt, Britta and Engelhardt, Britta and Sorokin, Lydia and Sorokin, Lydia
Acta neuropathologica, ISSN 0001-6322, 3/2013, Volume 125, Issue 3, pp. 395 - 412
Human | Pathology | Neurosciences | Medicine & Public Health | Mouse | Migration | Neurovascular unit | Polymorphonuclear granulocyte | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Blood Vessels - pathology | Humans | Blood-Brain Barrier - physiopathology | Male | Infarction, Middle Cerebral Artery - immunology | Antigens, CD - metabolism | Blood Vessels - physiopathology | Antigens, Ly - metabolism | Granulocytes - pathology | Disease Models, Animal | Endothelium - pathology | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation - physiology | Functional Laterality | Infarction, Middle Cerebral Artery - pathology | Cell Adhesion Molecules - metabolism | Blood-Brain Barrier - pathology | Glucose - deficiency | Oxygen - administration & dosage | Animals | Models, Biological | Brain - pathology | Hypoxia | Mice | Glucose metabolism | Permeability | Glucose | Ischemia | Proteases | Dextrose | Index Medicus | Neuroimaging | Brain | Cerebral infarction | Stroke | Leukocyte migration | Central nervous system | Parenchyma | Confocal microscopy | Basement membranes | Platelet aggregation | Macrophages | Endothelial cells | Cell adhesion molecules | Reperfusion | Cerebral blood flow | Leukocytes (granulocytic) | Brain injury | Life Sciences | Original Paper
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3. Full Text Mid-Gestation lethality of Atxn2l-Ablated Mice
by Key, Jana and Harter, Patrick N and Sen, Nesli-Ece and Gradhand, Elise and Auburger, Georg and Gispert, Suzana
International journal of molecular sciences, ISSN 1422-0067, 07/2020, Volume 21, Issue 14, p. 5124
Animal models | Phosphorylation | Transcription | Toxicity | Exons | Heterozygotes | Amino acids | Lipids | Lethality | Gestation | Glucose | Proteins | Embryogenesis | Developmental stages | Ataxin | Neurodegeneration | Cell cycle | Aging | Biocompatibility | Giant cells | Degeneration | Growth factors | Phenotypes | Starvation | Neurodegenerative diseases | Weight loss | Amyotrophic lateral sclerosis | Histology | Roles | Ribonucleic acid--RNA | Metabolism | Ablation | Cholesterol | Mutants | Homozygotes | Depletion | Placenta | Life span | Lamination | Surveillance | Apoptosis | Index Medicus | poly(A)-tail | Spinocerebellar ataxia type 2 | tauopathy | RNA chaperone | fronto-temporal lobar dementia | SCA2
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4. Full Text Genetic heterogeneity of primary lesion and metastasis in small intestine neuroendocrine tumors
by Walter, Dirk and Harter, Patrick N and Battke, Florian and Winkelmann, Ria and Schneider, Markus and Holzer, Katharina and Koch, Christine and Bojunga, Jörg and Zeuzem, Stefan and Hansmann, Martin Leo and Peveling-Oberhag, Jan and Waidmann, Oliver
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 3811 - 9
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Copy number | Liver | Genomes | Metastasis | Paraffin | Patients | Small intestine | Metastases | DNA methylation | Mutation | DNA sequencing | CpG islands | Neuroendocrine tumors | Tumors
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5. Full Text Bevacizumab for patients with recurrent multifocal glioblastomas
by Burger, Michael C and Breuer, Stella and Cieplik, Hans C and Harter, Patrick N and Franz, Kea and Bähr, Oliver and Steinbach, Joachim P
International journal of molecular sciences, ISSN 1661-6596, 11/2017, Volume 18, Issue 11, p. 2469
Multifocal | Anti-angiogenic therapy | Infiltration | Glioblastoma | Invasive growth | Bevacizumab | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Bevacizumab - administration & dosage | Humans | Middle Aged | Neoplasm Recurrence, Local - drug therapy | Male | Neoplasm Recurrence, Local - pathology | Disease-Free Survival | Magnetic Resonance Imaging | Angiogenesis Inhibitors - administration & dosage | Glioblastoma - diagnostic imaging | Antibodies, Monoclonal, Humanized - administration & dosage | Neoplasm Recurrence, Local - diagnostic imaging | Glioblastoma - pathology | Adult | Camptothecin - administration & dosage | Female | Aged | Glioblastoma - drug therapy | Camptothecin - analogs & derivatives | Therapy | Nuclear magnetic resonance--NMR | Brain cancer | Patients | Survival | Cancer therapies | Irinotecan | Magnetic resonance imaging | Antiangiogenics | Medical prognosis | Lesions | Index Medicus | invasive growth | bevacizumab | anti-angiogenic therapy | glioblastoma | infiltration | multifocal
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6. Full Text Differential utilization of ketone bodies by neurons and glioma cell lines: A rationale for ketogenic diet as experimental glioma therapy
by Maurer, Gabriele D and Brucker, Daniel P and Bähr, Oliver and Harter, Patrick N and Hattingen, Elke and Walenta, Stefan and Mueller-Klieser, Wolfgang and Steinbach, Joachim P and Rieger, Johannes
BMC cancer, ISSN 1471-2407, 07/2011, Volume 11, Issue 1, pp. 315 - 315
Life Sciences & Biomedicine | Oncology | Science & Technology | NIH 3T3 Cells | Rats, Wistar | Humans | Ketone Bodies - metabolism | Immunoblotting | Neurons - cytology | Glioma - diet therapy | Glioma - metabolism | Hydroxybutyrate Dehydrogenase - genetics | Coenzyme A-Transferases - genetics | Glioma - pathology | Female | Neurons - metabolism | Animals, Newborn | Cell Survival - drug effects | Diet, Ketogenic | Cells, Cultured | Rats | Glucose - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Acetyl-CoA C-Acetyltransferase - genetics | Hydroxybutyrate Dehydrogenase - metabolism | Xenograft Model Antitumor Assays | Coenzyme A-Transferases - metabolism | Animals | Mice, Nude | 3-Hydroxybutyric Acid - metabolism | Cell Line, Tumor | Glucose - metabolism | Mice | 3-Hydroxybutyric Acid - pharmacology | Acetyl-CoA C-Acetyltransferase - metabolism | Index Medicus
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7. Full Text CAR-Engineered NK Cells for the Treatment of Glioblastoma: Turning Innate Effectors Into Precision Tools for Cancer Immunotherapy
by Burger, Michael C and Zhang, Congcong and Harter, Patrick N and Romanski, Annette and Strassheimer, Florian and Senft, Christian and Tonn, Torsten and Steinbach, Joachim P and Wels, Winfried S
Frontiers in immunology, ISSN 1664-3224, 11/2019, Volume 10, pp. 2683 - 2683
Life Sciences & Biomedicine | Immunology | Science & Technology | Care and treatment | Killer cells | Brain tumors | Immunotherapy | Development and progression | Drug therapy | Glioblastoma multiforme | Cancer | Index Medicus | natural killer cells | chimeric antigen receptor | adoptive cancer immunotherapy | glioblastoma | NK-92
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8. Full Text The Space Physics Environment Data Analysis System (SPEDAS)
by Angelopoulos, V and Cruce, P and Drozdov, A and Grimes, E W and Hatzigeorgiu, N and King, D A and Larson, D and Lewis, J W and McTiernan, J M and Roberts, D A and Russell, C L and Hori, T and Kasahara, Y and Kumamoto, A and Matsuoka, A and Miyashita, Y and Miyoshi, Y and Shinohara, I and Teramoto, M and Faden, J B and Halford, A J and McCarthy, M and Millan, R M and Sample, J G and Smith, D M and Woodger, L A and Masson, A and Narock, A A and Asamura, K and Chang, T F and Chiang, C.-Y and Kazama, Y and Keika, K and Matsuda, S and