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by Savage, Jeanne E and Jansen, Philip R and Stringer, Sven and Watanabe, Kyoko and Bryois, Julien and de Leeuw, Christiaan A and Nagel, Mats and Awasthi, Swapnil and Barr, Peter B and Coleman, Jonathan R I and Grasby, Katrina L and Hammerschlag, Anke R and Kaminski, Jakob A and Karlsson, Robert and Krapohl, Eva and Lam, Max and Nygaard, Marianne and Reynolds, Chana A and Trampush, Joey W and Young, Hannah and Zabaneh, Delilah and Hägg, Sara and Hansell, Narelle K and Karlsson, Ida K and Linnarsson, Sten and Montgomery, Grant W and Muñoz-Manchado, Ana B and Quinlan, Erin B and Schumann, Gunter and Skene, Nathan G and Webb, Bradley T and White, Tonya and Arking, Dan E and Avramopoulos, Dimitrios and Bilder, Robert M and Bitsios, Panos and Burdick, Katherine E and Cannon, Tyrone D and Chiba-Falek, Ornit and Christoforou, Anea and Cirulli, Elizabeth T and Congdon, Eliza and Corvin, Aiden and Davies, Gail and Deary, Ian J and DeRosse, Pamela and Dickinson, Dwight and Djurovic, Srdjan and Donohoe, Gary and Conley, Emily bant and Eriksson, Johan G and Espeseth, Thomas and Freimer, Nelson A and Giakoumaki, Stella and Giegling, Ina and Gill, Michael and Glahn, David C and Hariri, Ahmad R and Hatzimanolis, Alex and Keller, Matthew C and Knowles, Emma and Koltai, Deborah and Konte, Bettina and Lahti, Jari and Le Hellard, Stephanie and Lencz, Todd and Liewald, David C and London, Edythe and Lundervold, Astri J and Malhotra, Anil K and Melle, Ingrid and Morris, Derek and Need, Anna C and Ollier, William and Palotie, Aarno and Payton, Antony and Pendleton, Neil and Polack, Russell A and Räikkönen, Katri and Reinvang, Ivar and Roussos, Panos and Rujescu, Dan and Sabb, Fred W and Scult, Matthew A and Smeland, Olav B and Smyrnis, Nikolaos and Starr, John M and Steen, Vidar M and Stefanis, Nikos C and Straub, Richard E and Sundet, Kjetil and Tiemeier, Henning and Voineskos, Aristotle N and Weinberger, Daniel R and Widen, Elisabeth and Yu, Jin and Abecasis, Goncalo and Aneassen, Ole A and Breen, Gerome and Christiansen, Lene and ...
Nature Genetics, ISSN 1061-4036, 07/2018, Volume 50, Issue 7, pp. 912 - 919
Intelligence is highly heritable1 and a major determinant of human health and well-being2. Recent genome-wide meta-analyses have identified 24 genomic loci... 
Genetics | GENERAL COGNITIVE FUNCTION | CONSORTIUM | TEST BATTERIES | GWAS | ANNOTATION | GENETICS & HEREDITY | RISK | LOCI | EDUCATIONAL-ATTAINMENT | TRAITS | HERITABILITY | Brain | Chromatin | Neurosciences | Intelligence | Synaptogenesis | Mental disorders | Genomics | Genes | Cognitive ability | Schizophrenia | Association analysis | Nervous system | Identification | Mapping | Genomes | Genetic effects | Annotations | Coding | Genetic analysis | Neostriatum | Alzheimer's disease | Bioinformatics | Neurodegenerative diseases | Neurons | Attention deficit hyperactivity disorder | Causation | Gene expression | Spiny neurons | Loci | Educational attainment | Meta-analysis | Quantitative trait loci | Neurological diseases | Studies | Pyramidal cells | Gene loci | Gene mapping | Alzheimers disease | Hippocampus | Medical and Health Sciences | Medicin och hälsovetenskap | Alzheimer disease | Article | nervous system development | genetic association | gene location | schizophrenia | Klinisk medicin | pleiotropy | gene mapping | genetic correlation | priority journal | human | Neurologi | corpus striatum | hippocampus | synapse | chromatin | heredity | genetic variability | intelligence | pyramidal nerve cell | gene locus | Mendelian randomization analysis | Clinical Medicine | Neurology | expression quantitative trait locus | medium spiny neuron | genome-wide association study | attention deficit disorder | exon | conserved sequence | gene expression
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0116696
Inflammation and maternal or fetal infections have been suggested as risk factors for schizophrenia (SZ) and bipolar disorder (BP). It is likely that such... 
C-REACTIVE PROTEIN | ANTIBODIES | IMMUNE-RESPONSE | KINASE SGK1 | RISK LOCI | TOXOPLASMA-GONDII INFECTION | MULTIDISCIPLINARY SCIENCES | ONSET SCHIZOPHRENIA | MILITARY PERSONNEL | PSYCHIATRIC-DISORDERS | AGENTS | Toxoplasma - immunology | Antibodies, Viral - metabolism | Humans | Parents | Male | Schizophrenia - complications | Toxoplasma - physiology | Virus Diseases - complications | Case-Control Studies | Schizophrenia - parasitology | Genetic Variation | Inflammation - complications | Schizophrenia - genetics | Toxoplasmosis - complications | Female | Bipolar Disorder - parasitology | Genetic Predisposition to Disease | Genome-Wide Association Study | Bipolar Disorder - complications | C-Reactive Protein - genetics | Bipolar Disorder - genetics | Schizophrenia - virology | Polymorphism, Single Nucleotide | Antibodies, Protozoan - metabolism | Bipolar Disorder - virology | Medical research | C-reactive protein | Genomics | Bipolar disorder | Genomes | Inflammation | Infection | Analysis | Medicine, Experimental | Cytomegalovirus infections | Genetic aspects | Single nucleotide polymorphisms | Health aspects | IgG antibody | Mental disorders | Immunoglobulin G | Herpes simplex | Schizophrenia | Viruses | Infections | Single-nucleotide polymorphism | Immunity | Epidemiology | Risk factors | Proteins | Psychosis | Body mass index | Gliadin | Genotypes | Public health | Antigens | Permutations | Cytomegalovirus | Immunoglobulins | Fetuses | Health risks | Chromosome 6 | Genetic diversity | Risk analysis | Gene expression | Environmental effects | Medicine | Studies | Genetic variance | Body mass | Body size | Herpes viruses | Histocompatibility antigen HLA | Psychiatry | Smoking
Journal Article
by Culverhouse, R C and Saccone, N L and Horton, A C and Ma, Y and Anstey, K J and Banaschewski, T and Burmeister, M and Cohen-Woods, S and Etain, B and Fisher, H L and Goldman, N and Guillaume, S and Horwood, J and Juhasz, G and Lester, K J and Mandelli, L and Middeldorp, C M and Olié, E and Villafuerte, S and Air, T M and Araya, R and Bowes, L and Burns, R and Byrne, E M and Coffey, C and Coventry, W L and Gawronski, K A B and Glei, D and Hatzimanolis, A and Hottenga, J-J and Jaussent, I and Jawahar, C and Jennen-Steinmetz, C and Kramer, J R and Lajnef, M and Little, K and Zu Schwabedissen, H M and Nauck, M and Nederhof, E and Petschner, P and Peyrot, W J and Schwahn, C and Sinnamon, G and Stacey, D and Tian, Y and Toben, C and Van der Auwera, S and Wainwright, N and Wang, J-C and Willemsen, G and Anderson, I M and Arolt, V and Åslund, C and Bagdy, G and Baune, B T and Bellivier, F and Boomsma, D I and Courtet, P and Dannlowski, U and de Geus, E J C and Deakin, J F W and Easteal, S and Eley, T and Fergusson, D M and Goate, A M and Gonda, X and Grabe, H J and Holzman, C and Johnson, E O and Kennedy, M and Laucht, M and Martin, N G and Munafò, M R and Nilsson, K W and Oldehinkel, A J and Olsson, C A and Ormel, J and Otte, C and Patton, G C and Penninx, B W J H and Ritchie, K and Sarchiapone, M and Scheid, J M and Serretti, A and Smit, J H and Stefanis, N C and Surtees, P G and Völzke, H and Weinstein, M and Whooley, M and Nurnberger, J I and Breslau, N and Bierut, L J and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Centrum för klinisk forskning, Västerås
Molecular Psychiatry, ISSN 1359-4184, 2018, Volume 23, Issue 1, pp. 133 - 142
The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is associated with increased risk of depression, but only in individuals... 
SAMPLE | COHORT PROFILE | CHILDHOOD MALTREATMENT | ENVIRONMENT INTERACTION | POLYMORPHISM 5-HTTLPR | DISORDER | RISK | MAJOR DEPRESSION | SEROTONIN TRANSPORTER GENE | LIFE EVENTS | Journal Article | PSYCHIATRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | Stress, Psychological - genetics | Genetic Predisposition to Disease | Serotonin Plasma Membrane Transport Proteins - genetics | Humans | Life Change Events | Cooperative Behavior | Depression - psychology | Genotype | Depression - genetics | Gene-Environment Interaction | Stress, Psychological - complications | Genetic aspects | Research | Depression, Mental | Risk factors | Data analysis | Statistical analysis | Serotonin | Data processing | Mental depression | Subgroups | Strong interactions (field theory) | Consortia | Genotype & phenotype | Hypotheses | Serotonin transporter | Alleles | Children | Transporter | Genotypes | Life Sciences | Neurologi | Basic Medicine | Biological Sciences | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | Hälsovetenskaper | Klinisk medicin | Clinical Medicine | Neurology | Occupational Health and Environmental Health | Naturvetenskap | Biokemi och molekylärbiologi | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Arbetsmedicin och miljömedicin | Psykiatri | Biochemistry and Molecular Biology | Natural Sciences | Psychiatry | Health Sciences | Neurovetenskaper
Journal Article
by Davies, Gail and Lam, M and Harris, Sarah and Trampush, J.W and Luciano, Michelle and Hill, W.D and Hagenaars, Saskia and Ritchie, S.J and Marioni, Riccardo and Fawns-Ritchie, C and Liewald, D.C.M and Okely, J.A and Ahola-Olli, A.V and Barnes, C.L.K and Bertram, Lars and Bis, Joshua and Burdick, K.E and Christoforou, Anea and Derosse, P and Djurovic, Srdjan and Espeseth, Thomas and Giakoumaki, S and Giddaluru, Sudheer and Gustavson, D.E and Hayward, Caroline and Hofer, Edith and Ikram, Arfan and Karlsson, Robert and Knowles, E and Lahti, Jari and Leber, Isabelle and Li, S and Mather, R and Melle, Ingrid and Morris, D and Oldmeadow, Christopher and Palviainen, T and Payton, Antony and Pazoki, Raha and Petrovic, Katja and Reynolds, C and Sargurupremraj, M and Scholz, Markus and Smith, Jennifer A and Smith, Albert and Terzikhan, Natalie and Thalamuthu, Anbupalam and Trompet, Stella and Lee, Sven and Ware, Erin B and Windham, B Gwen and Wright, M.J and Yang, J and Yu, J and Ames, David and Amin, Najaf and Amouyel, Philippe and Aneassen, Ole and Armstrong, Nicola J and Assareh, A.A and Attia, John and Attix, D and Avramopoulos, D and Bennett, David and Böhmer, Marcel and Boyle, P.A and Brodaty, Henry and Campbell, Harry and Cannon, T.D and Cirulli, E.T and Congdon, E and Conley, E.D and Corley, J and Cox, Simon R and Dale, Anders and Dehghan, Abbas and Dick, D and Dickinson, D and Hagen, Knut and Evangelou, Evangelos and Faul, Jessica D and Ford, Ian and Freimer, N.A and Gao, H and Giegling, Ina and Gillespie, N.A and Gordon, Scott D and Gottesman, Rebecca and Griswold, Michael and Gudnason, V and Harris, Tamara and Hartmann, Annette M and Hatzimanolis, A and Heiss, Gerardo and Holliday, Elizabeth and Joshi, Peter and Kähönen, Mika and Kardia, S.L.R and Karlsson, I and Kleineidam, L and ...
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2098 - 16
textabstractGeneral cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine... 
COMMON VARIANTS | METAANALYSIS | REACTION-TIME | PROCESSING SPEED | MULTIDISCIPLINARY SCIENCES | INTELLIGENCE DIFFERENCES | SCHIZOPHRENIA | DCDC2 | DISCOVERY | GENOME-WIDE ASSOCIATION | REVEALS | Multifactorial Inheritance - genetics | Genetic Predisposition to Disease | Humans | Middle Aged | Genetic Loci - genetics | Neurodegenerative Diseases - genetics | Neurodevelopmental Disorders - genetics | Reaction Time - genetics | Young Adult | Mental Disorders - genetics | Adolescent | Aged, 80 and over | Cognition - physiology | Polymorphism, Single Nucleotide - genetics | Adult | Aged | Hypertension | Brain | Cognitive ability | Genomes | Gene expression | Neurodevelopmental disorders | Loci | Consortia | Illnesses | Mathematical analysis | Reaction time | Heritability | Gene loci | Polygenic inheritance | brain cortex | Medical and Health Sciences | Medicin och hälsovetenskap | major clinical study | osteoarthritis | Article | heart infarction | Klinisk medicin | lung cancer | identification method | longevity | grip strength | angina pectoris | genetic correlation | human | major depression | Neurologi | cognition | data set | aged | brain | gene locus | Clinical Medicine | Neurology | genome | vision | genetic analysis | controlled study | response time | adolescent | nervous system disorder | adult | hypertension | gene expression
Journal Article
Current Allergy and Asthma Reports, ISSN 1529-7322, 2/2018, Volume 18, Issue 2, pp. 1 - 18
Journal Article
Cell Reports, ISSN 2211-1247, 11/2017, Volume 21, Issue 9, pp. 2597 - 2613
Journal Article
Cell, ISSN 0092-8674, 11/2019, Volume 179, Issue 6, pp. 1424 - 1435.e8
The increasing proportion of variance in human complex traits explained by polygenic scores, along with progress in preimplantation genetic diagnosis, suggests... 
quantitative genetics | polygenic scores | embryo screening | complex traits | embryo selection | pre-implantation genetic testing | cognitive ability | height | HUMAN HEIGHT | IN-VITRO | RISK PREDICTION | GENETIC DIAGNOSIS | PERFORMANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMMON | LIVE-BIRTH | SELECTION | COMPLEX TRAITS | GENOME-WIDE ASSOCIATION | CELL BIOLOGY
Journal Article