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PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, pp. e0198389 - e0198389
Background Niclosamide, an FDA-approved anti-helminthic drug, has activity in preclinical models of castration-resistant prostate cancer (CRPC). Potential... 
CELLS | RECEPTOR SPLICE VARIANTS | INHIBITION | MULTIDISCIPLINARY SCIENCES | ANDROGEN-RECEPTOR | CLINICAL-TRIALS | THERAPY RESISTANCE | KAPPA-B PATHWAY | INCREASED SURVIVAL | PROGRESSION | ABIRATERONE | Phenylthiohydantoin - adverse effects | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Niclosamide - pharmacokinetics | Male | Prostatic Neoplasms, Castration-Resistant - drug therapy | Prostatic Neoplasms, Castration-Resistant - metabolism | Phenylthiohydantoin - analogs & derivatives | Prostatic Neoplasms, Castration-Resistant - pathology | Dose-Response Relationship, Drug | Phenylthiohydantoin - administration & dosage | Maximum Tolerated Dose | Neoplasm Metastasis | Niclosamide - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged, 80 and over | Aged | Cell Proliferation - drug effects | Niclosamide - adverse effects | Drug Resistance, Neoplasm - drug effects | Phenylthiohydantoin - pharmacokinetics | Anthelmintics | Dosage and administration | Drug therapy, Combination | Drug therapy | Prostate cancer | Methods | Testing | Slopes | Alternative splicing | Wnt protein | Toxicity | Niclosamide | Oncology | Biology | Metastasis | Drug resistance | Metastases | Castration | Vomiting | Safety | Drug dosages | Medical research | Tumor cells | Diarrhea | Nausea | Pharmacology | Bioavailability | Patients | Augmented reality | Constraining | Medicine | Androgens | Ligands | Colitis | Mutation | Pharmacokinetics | Prostate | Cancer | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 2018, Volume 13, Issue 8, p. e0202709
[This corrects the article DOI: 10.1371/journal.pone.0198389.]. 
Niclosamide | Castration | Prostate cancer | Prostate | Cancer
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 2114 - 2114
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 2324 - 2324
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 1, pp. 288 - 304
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2009, Volume 15, Issue 24, pp. 7634 - 7641
Purpose: Inhibition of insulin-like growth factor (IGF) signaling using the human IGF-I receptor monoclonal antibody A12 is most effective at inducing... 
androgen | A12 | IGF-IR | TSC-22 | castrate-resistant prostate cancer | EPITHELIAL-CELLS | ONCOLOGY | CELL LINE | DOWN-REGULATION | TUMOR-SUPPRESSOR | DIFFERENTIATION | IDENTIFICATION | EXPRESSION | SALIVARY-GLAND CANCER | T-ANTIGEN
Journal Article
Neoplasia (New York, N.Y.), ISSN 1522-8002, 9/2013, Volume 15, Issue 9, pp. 1009 - 1017
Androgen deprivation therapy remains the primary treatment modality for patients with metastatic prostate cancer but is uniformly marked by progression to... 
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 05/2013, Volume 98, Issue 5, pp. E820 - E828
Context: Prostate cancer patients at increased risk for relapse after prostatectomy were treated in a neoadjuvant study with androgen deprivation therapy (ADT)... 
TARGETED THERAPY | FACTOR RECEPTOR ANTIBODY | GLUCOSE-HOMEOSTASIS | HORMONE-THERAPY | EFFICACY | BIOCHEMICAL RECURRENCE | ENDOCRINOLOGY & METABOLISM | RESISTANCE | PHASE-II | RADICAL PROSTATECTOMY | DOCETAXEL | Receptor, IGF Type 1 - metabolism | United States - epidemiology | Anilides - therapeutic use | Receptor, IGF Type 1 - antagonists & inhibitors | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Antibodies, Monoclonal - therapeutic use | Male | Risk | Antineoplastic Agents - therapeutic use | Secondary Prevention | Antineoplastic Agents - administration & dosage | Insulin - blood | Nitriles - administration & dosage | Neoadjuvant Therapy | Prostatic Neoplasms - prevention & control | Goserelin - therapeutic use | Prostatic Neoplasms - drug therapy | Somatomedins - analysis | Body Mass Index | Goserelin - administration & dosage | Tosyl Compounds - administration & dosage | Prostatic Neoplasms - surgery | Obesity - complications | Insulin Resistance | Adenocarcinoma - drug therapy | Adenocarcinoma - complications | Adenocarcinoma - prevention & control | Anilides - administration & dosage | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Tosyl Compounds - therapeutic use | Androgen Antagonists - therapeutic use | Insulin-Like Growth Factor Binding Protein 1 - blood | Prostatectomy | Prostatic Neoplasms - complications | Androgen Antagonists - administration & dosage | Adenocarcinoma - surgery | Cohort Studies | Nitriles - therapeutic use | 100 | 500 | Hot Topics in Translational Endocrinology
Journal Article
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. 631 - 631
Journal Article
Endocrinology, ISSN 0013-7227, 1995, Volume 136, Issue 8, pp. 3669 - 3672
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 12/2009, Volume 15, Issue 24, pp. 7634 - 7641
Journal Article
ENDOCRINOLOGY, ISSN 0013-7227, 08/1995, Volume 136, Issue 8, pp. 3669 - 3672
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 12/2009, Volume 15, Issue 24, pp. 7634 - 7641
PURPOSE: Inhibition of insulin-like growth factor (IGF) signaling using the human IGF-I receptor monoclonal antibody A12 is most effective at inducing... 
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/1997, Volume 239, Issue 1, pp. 6 - 10
Journal Article
Journal Article
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