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index medicus (74) 74
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p53 (36) 36
cell biology (33) 33
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2016, ISBN 9782889199617
TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single amino acid change and are... 
mouse models | mutant p53 | dominant netagive | therapies | Oncogenic addiction | gain of function
eBook
Nature Medicine, ISSN 1078-8956, 08/2012, Volume 18, Issue 8, pp. 1239 - 1247
The inactivation of the p53 tumor suppressor pathway, which often occurs through mutations in TP53 (encoding tumor protein 53) is a common step in human... 
MEDICINE, RESEARCH & EXPERIMENTAL | N-RAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-SUPPRESSOR ACTIVITY | STAPLED P53 | BRAF | MALIGNANT-MELANOMA | P53 PATHWAY | CELL-DEATH | CELL BIOLOGY | BREAST-CANCER | METASTATIC MELANOMA | IN-VIVO | Up-Regulation | Proto-Oncogene Proteins c-mdm2 - genetics | Tumor Suppressor Protein p53 - antagonists & inhibitors | Apoptosis - drug effects | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Recombinant Fusion Proteins - physiology | Skin Neoplasms - chemistry | Male | Melanocytes - metabolism | Neoplasm Proteins - antagonists & inhibitors | Cell Line, Tumor - transplantation | Proto-Oncogene Proteins - biosynthesis | Tumor Suppressor Protein p53 - physiology | Cell-Penetrating Peptides - pharmacology | Nuclear Proteins - biosynthesis | Female | Antineoplastic Agents - pharmacology | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Cell Line, Tumor - metabolism | Melanoma - chemistry | Proto-Oncogene Proteins c-mdm2 - biosynthesis | Proto-Oncogene Proteins - antagonists & inhibitors | Tumor Stem Cell Assay | Membrane Proteins - genetics | Neoplasm Proteins - biosynthesis | Melanoma, Experimental - etiology | Mice, Inbred C57BL | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Melanoma - pathology | Melanoma - secondary | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Melanoma, Experimental - genetics | GTP Phosphohydrolases - genetics | Keratinocytes - metabolism | Mice, Nude | Nuclear Proteins - antagonists & inhibitors | Proto-Oncogene Proteins - physiology | Signal Transduction - physiology | Mice | Nuclear Proteins - physiology | Drug Resistance, Neoplasm - physiology | Drug Resistance, Neoplasm - drug effects | Care and treatment | Gene mutations | Melanoma | Diagnosis | Research | Gene expression | Identification and classification | Skin cancer | Proteins | Cell growth | Mutation | Cell cycle | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 03/2017, Volume 8, Issue 1, pp. 14844 - 14844
  TP53, a critical tumour suppressor gene, is mutated in over half of all cancers resulting in mutant-p53 protein accumulation and poor patient survival.... 
Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 06/2015, Volume 6, Issue 1, pp. 7389 - 7389
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2014, Volume 88, Issue 2, pp. 385 - 394
Journal Article
Frontiers in Oncology, ISSN 2234-943X, 07/2016, Volume 6, pp. 170 - 170
Journal Article
Gut, ISSN 0017-5749, 07/2015, Volume 64, Issue 10, pp. 1506 - 1516
Journal Article
Cell Cycle, ISSN 1538-4101, 2004, Volume 3, Issue 7, pp. 884 - 885
Mdm2 | Pin1 | p63 | p73 | Mdmx | p53
Journal Article
Human Mutation, ISSN 1059-7794, 06/2019, Volume 40, Issue 6, pp. 788 - 800
Germline pathogenic variants in the TP53 gene cause Li‐Fraumeni syndrome, a condition that predisposes individuals to a wide range of cancer types.... 
variant classification | Li‐Fraumeni syndrome | TP53 | quantitative | Li-Fraumeni syndrome | MUTATION CARRIERS | LI-FRAUMENI | SEQUENCE VARIANTS | CLASSIFICATION | RISK | BRCA1 | BREAST-CANCER | GENOMICS | P53 GENE | RECOMMENDATIONS | GENETICS & HEREDITY | Algorithms | Sarcoma | Tumor proteins | Analysis | Genes | Pathogenicity | Radiation therapy | AMP | p53 Protein
Journal Article
Journal Article