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International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 11/2018, Volume 102, Issue 3, pp. e182 - e182
Journal Article
by McKay, J.D and Hung, R.J and Han, Y and Zong, X and Carreras-Torres, R and Christiani, D.C and Caporaso, N and Johansson, M and Li, Y and Byun, J.Y and Dunning, A and Pooley, K.A and Qian, D.C and Liu, G and Bojesen, S.E and Wu, X and Marchand, L. le and Albanes, D and Bickeböller, H and Alich, M.C and Bush, W.S and Tardon, A and Rennert, G and Teare, M.D and Field, J.K and Kiemeney, L.A and Lazarus, P and Haugen, A and Schabath, M.B and Anew, A.S and Shen, H and Hong, Y.C and Yuan, J.M and Bertazzi, P.A and Pesatori, A.C and Ye, Y and Diao, N and Su, L and Zhang, R and Brhane, Y and Leighl, N and Johansen, J.S and Mellemgaard, A and Saliba, W and Haiman, C.A and Wilkens, L.R and Fernandez-Somoano, A and Fernandez-Tardon, G and Heijden, H.F.M. van der and Kim, J.H and Hu, Z and Davies, M and Brunnström, H and Manjer, J and Melander, O and Muller, D and Overvad, K and Trichopoulou, A and Tumino, R and Doherty, J.A and Barnett, M.P and Chen, C and Goodman, G.E and Cox, A and Taylor, F and Woll, P.J and Brüske, I and Wichmann, H.E and Manz, J and Muley, T.R and Risch, A and Rosenberger, A and Grankvist, K and Shepherd, F.A and Tsao, M.S and Haura, E.B and Bolca, C and Holcatova, I and Janout, V and Kontic, M and Lissowska, J and Mukeria, A and Ognjanovic, S and Orlowski, T.M and Scelo, G and Swiatkowska, B and Zaridze, D and Bakke, P and Skaug, V and Zienolddiny, S and Duell, E.J and Butler, L.M and Koh, W.P and Gao, Y.T and Houlston, R.S and McLaughlin, J and Stevens, V.L and Joubert, P and Lamontagne, M and Nickle, D.C and ... and SpiroMeta Consortium and Medicinska fakulteten and Institutionen för medicinsk biovetenskap and Institutionen för strålningsvetenskaper and Umeå universitet
Nature Genetics, ISSN 1061-4036, 2017, Volume 49, Issue 7, pp. 1126 - 1132
Journal Article
Oncogene, ISSN 0950-9232, 06/2016, Volume 35, Issue 24, pp. 3209 - 3216
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 09/2019, Volume 105, Issue 1, pp. S36 - S36
Journal Article
Oncogene, ISSN 0950-9232, 01/2013, Volume 32, Issue 2, pp. 151 - 159
Serine/threonine kinase IKBKE is a newly identified oncogene; however, its regulation remains elusive. Here, we provide evidence that IKBKE is a downstream... 
lung cancer | chemosensitivity | tobacco carcinogen | IKBKE | STAT3 | IKK-EPSILON | BIOCHEMISTRY & MOLECULAR BIOLOGY | NICOTINIC RECEPTOR | TUMOR-SUPPRESSOR CYLD | CELL BIOLOGY | BREAST-CANCER | PULMONARY NEUROENDOCRINE CELLS | B KINASE-EPSILON | EPITHELIAL-CELLS | ONCOLOGY | IN-VIVO | GENETICS & HEREDITY | GENE-EXPRESSION | SRC ONCOPROTEIN | Ketones - pharmacology | Lung Neoplasms - genetics | Promoter Regions, Genetic | Cell Proliferation | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Cell Survival | Humans | Lung Neoplasms - metabolism | RNA, Messenger - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | I-kappa B Kinase - genetics | RNA, Messenger - metabolism | Nicotine - pharmacology | Tobacco | I-kappa B Kinase - metabolism | RNA Interference | Nitrosamines - pharmacology | RNA, Small Interfering | STAT3 Transcription Factor - antagonists & inhibitors | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Smoking | Immune response | Physiological aspects | Drug metabolism | Diagnosis | Research | Lung cancer, Non-small cell | Tobacco products | Health aspects | Risk factors | Oncology | Carcinogens | Kinases | Lung cancer | Cell survival | Transcription | Chemoresistance | Stat3 protein | Nitrosamines | Non-small cell lung carcinoma | Data processing | ketones | Carcinogenesis | Promoters | Chemotherapy | Protein-serine/threonine kinase | Cigarette smoke | Oncogenes | Nicotine | Index Medicus
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 12/2017, Volume 13, Issue 12, pp. 1222 - 1231
Targeted drugs are effective when they directly inhibit strong disease drivers, but only a small fraction of diseases feature defined actionable drivers.... 
ANAPLASTIC LYMPHOMA KINASE | LUNG-CANCER | FAK | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESISTANCE | MECHANISMS | FOCAL ADHESION KINASE | ANTITUMOR-ACTIVITY | INHIBITOR | IDENTIFICATION | DISCOVERY | Lung Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Structure-Activity Relationship | Polypharmacology | Sulfones - pharmacology | Pyrimidines - chemistry | Dose-Response Relationship, Drug | Protein Kinase Inhibitors - chemistry | RNA Interference | Microtubules - drug effects | Sulfones - chemistry | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Molecular Structure | Carcinoma, Non-Small-Cell Lung - pathology | Cell Survival - drug effects | Carcinoma, Non-Small-Cell Lung - metabolism | Pyrimidines - pharmacology | Antineoplastic Agents - chemistry | Receptor Protein-Tyrosine Kinases - metabolism | Proteomics | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Drug Screening Assays, Antitumor | Drugs | Target recognition | Taxol | RNA-mediated interference | Lung cancer | Pharmacology | Tumor cell lines | Drug development | Ribonucleic acid--RNA | Lymphoma | Ribosomal protein S6 kinase | Signaling | Inhibitors | Cell lines | Paclitaxel | Biomarkers | Focal adhesion kinase | Protein-tyrosine kinase | Cancer
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 08/2017, Volume 12, Issue 8, pp. S1540 - S1540
Journal Article
PLoS One, ISSN 1932-6203, 2017, Volume 12, Issue 6, p. e0177875
BACKGROUND: Assessing the relationship between lung cancer and metabolic conditions is challenging because of the confounding effect of tobacco. Mendelian... 
GENETIC-VARIATION | IDENTIFY | VARIANTS | MULTIDISCIPLINARY SCIENCES | BODY-MASS INDEX | LINK | ADIPOSITY | TRAITS | INSIGHTS | LIPIDS | Body Mass Index | Fasting | Obesity - complications | Humans | Lung Neoplasms - metabolism | Risk Factors | Insulin Resistance | Lung Neoplasms - pathology | Insulin - blood | Obesity - blood | Lung Neoplasms - complications | Likelihood Functions | Phenotype | Lipids - blood | Mendelian Randomization Analysis | Lung Neoplasms - blood | Polymorphism, Single Nucleotide | Care and treatment | Lung cancer | Development and progression | Genotype | Genetic aspects | Models | Health aspects | Mendel's law | Adenocarcinoma | Health care | Thoracic surgery | Laboratories | Identification methods | Oncology | Metabolic syndrome | Density | Epidemiology | Risk factors | Prevention | Body mass index | Randomization | Etiology | Risk assessment | Genetics | Standard deviation | Public health | Consumption | Obesity | Medical research | Squamous cell carcinoma | Sensitivity analysis | Small cell lung carcinoma | Health risks | Preventive medicine | Cigarettes | Risk analysis | Cigarette smoking | Insulin | Cholesterol | Tobacco | Sensitivity | Body mass | Lungs | Diabetes | Risk management | Smoking | Cancer | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 08/2017, Volume 12, Issue 8, pp. S1540 - S1540
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 11/2017, Volume 23, Issue 22, pp. 7084 - 7096
Purpose: Targeting MET in cancer is hampered by lack of diagnostics that accurately reflect high MET signaling and dependence. We hypothesized that assays... 
CELL LUNG-CANCER | AMPLIFICATION | ONCOLOGY | ADENOCARCINOMA | C-MET | RESISTANCE | CRIZOTINIB | MUTATIONS | 14 SKIPPING ALTERATIONS | EXPRESSION | EGFR | Cell culture | Alternative splicing | Lung cancer | Assaying | Grb2 protein | Amplification | Signaling | Gene amplification | Experimental design | Cell lines | Xenografts | MET protein | Solid tumors | Viability | Tumors | Cancer | crizotinib | proximity ligation | cMET
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2016, Volume 126, Issue 6, pp. 2267 - 2279
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13, pp. 3551 - 3563
Journal Article
Journal Article