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2013, ISBN 9780932216694, 104 pages
"Robert Davidson has been a pivotal figure in the Northwest Coast Native art renaissance since he erected the first totem pole in nearly a century in his... 
Davidson, Robert, 1946
Book
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2007, Volume 43, Issue 6, pp. 686 - 695
Abstract Protein kinase D (PKD) is activated downstream of protein kinase C (PKC) in many cell types, although little is known about the mechanisms that... 
Cardiovascular | PKD | PKC | cTnI | Adenovirus | Cardiac myocytes | PKA
Journal Article
Circulation Research, ISSN 0009-7330, 11/2004, Volume 95, Issue 11, pp. 1091 - 1099
Protein kinase D (PKD) is a serine kinase whose myocardial substrates are unknown. Yeast 2-hybrid screening of a human cardiac library, using the PKD catalytic... 
Cardiac troponin I | Calcium sensitivity | Protein phosphorylation | Protein kinase D | Contractile function | Crossbridge cycling kinetics | C FAMILY | contractile function | SARCOMERIC M-BAND | CARDIAC & CARDIOVASCULAR SYSTEMS | ATPASE ACTIVITY | RAT | MUSCLE | protein phosphorylation | cardiac troponin I | calcium sensitivity | POWER OUTPUT | protein kinase D | PERIPHERAL VASCULAR DISEASE | MOLECULAR-CLONING | crossbridge cycling kinetics | HEMATOLOGY | PHORBOL ESTERS | SIGNAL-TRANSDUCTION PATHWAY | MYOSIN-BINDING | Protein Kinase C - genetics | Phosphorylation | Connectin | Rats, Wistar | Humans | Middle Aged | Myocardial Contraction - physiology | DNA, Complementary - genetics | Molecular Sequence Data | Substrate Specificity | Male | Structure-Activity Relationship | Recombinant Fusion Proteins - metabolism | Protein Kinase C - metabolism | Troponin I - genetics | Myocardium - metabolism | Muscle Proteins - metabolism | Adult | Isometric Contraction | Calcium Signaling | Cyclic AMP-Dependent Protein Kinases - metabolism | Amino Acid Sequence | Actin Cytoskeleton - metabolism | Mutagenesis, Site-Directed | Rats | Protein Processing, Post-Translational - physiology | Phosphoserine - analysis | Two-Hybrid System Techniques | Animals | Carrier Proteins - metabolism | Myocytes, Cardiac - metabolism | Troponin I - chemistry | Troponin I - metabolism | Amino Acid Substitution
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2014, Volume 289, Issue 3, pp. 1282 - 1293
Journal Article
Biochemical Journal, ISSN 0264-6021, 02/2014, Volume 457, Issue 3, pp. 451 - 461
PKD (protein kinase D) is a serine/threonine kinase implicated in multiple cardiac roles, including the phosphorylation of the class II HDAC5 (histone... 
Histone deacetylase | Signal transduction | Four-and-a-half LIM (FHL) | Cardiac myocyte | Neurohormonal stimulation | Protein kinase | four-and-a-half LIM (FHL) | PRESSURE-OVERLOAD | HISTONE-DEACETYLASE KINASE | neurohormonal stimulation | signal transduction | BIOCHEMISTRY & MOLECULAR BIOLOGY | FHL2 | NUCLEAR EXPORT | CARDIOMYOCYTES | histone deacetylase | cardiac myocyte | protein kinase | TROPONIN-I | HYPERTROPHIC RESPONSE | GENE-EXPRESSION | METABOLIC ENZYMES | TRANSCRIPTION FACTOR | Protein Kinase C - genetics | Heart Ventricles - cytology | Phosphorylation | Transcription Factors - chemistry | LIM-Homeodomain Proteins - metabolism | Humans | Intracellular Signaling Peptides and Proteins - metabolism | LIM-Homeodomain Proteins - antagonists & inhibitors | LIM Domain Proteins - metabolism | Recombinant Fusion Proteins - metabolism | Isoenzymes - metabolism | Protein Kinase C - metabolism | Muscle Proteins - metabolism | Muscle Proteins - antagonists & inhibitors | Intracellular Signaling Peptides and Proteins - genetics | Peptide Fragments - genetics | LIM Domain Proteins - chemistry | Animals, Newborn | Peptide Fragments - metabolism | Myocytes, Cardiac - cytology | Endothelin-1 - metabolism | Isoenzymes - genetics | LIM-Homeodomain Proteins - chemistry | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | LIM Domain Proteins - antagonists & inhibitors | Cells, Cultured | Rats | Histone Deacetylases - metabolism | Transcription Factors - antagonists & inhibitors | Recombinant Fusion Proteins - chemistry | Transcription Factors - genetics | Muscle Proteins - genetics | Transcription Factors - metabolism | LIM-Homeodomain Proteins - genetics | Peptide Fragments - chemistry | Animals | Intracellular Signaling Peptides and Proteins - chemistry | Peptide Fragments - antagonists & inhibitors | MEF2 Transcription Factors - metabolism | Myocytes, Cardiac - metabolism | LIM Domain Proteins - genetics | Heart Ventricles - metabolism | Mice | Muscle Proteins - chemistry | Protein Processing, Post-Translational | Enzyme Activation | FHL, four-and-a-half LIM domains | PKD, protein kinase D | MEF2, myocyte enhancer factor 2 | MuRF, muscle RING finger | ARVM, adult rat ventricular myocyte | ERK, extracellular-signal-regulated kinase | caPKD, constitutively active catalytic domain of PKD | BPKDi, bipyridyl PKD inhibitor | CaMK, Ca2 | PE, phenylephrine | HDAC, histone deacetylase | calmodulin-dependent protein kinase | PKC, protein kinase C | cMyBP-C, cardiac myosin-binding protein C | IVK, in vitro kinase | TAC, transverse aortic constriction | CRM1, chromosome region maintenance 1 | pfu, plaque-forming unit | ET1, endothelin 1 | cTnI, inhibitory subunit of cardiac troponin | MOI, multiplicity of infection | NRVM, neonatal rat ventricular myocyte
Journal Article
Circulation Research, ISSN 0009-7330, 03/2007, Volume 100, Issue 6, pp. 864 - 873
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 11/1999, Volume 85, Issue 10, pp. 919 - 919
Increased sarcolemmal Na/H exchanger activity has been implicated as a mediator of the cardiac actions of angiotensin II. We studied the receptor subtypes and... 
Signal transduction | Na | Angiotensin | exchanger | Extracellular signal-regulated kinase | H | Myocyte
Journal Article
Biochemical Journal, ISSN 0264-6021, 11/2006, Volume 399, Issue 3, pp. 493 - 501
In cardiac myocytes, sustained (3 min) intracellular acidosis activates the ERK1/2 (extracellular-signal-regulated kinase 1/2) pathway and, through this... 
Extracellular-signal-regulated kinase (ERK) pathway | Ras | Raf | Cardiac myocyte | G-protein-coupled receptor (GPCR) | Acidosis | Protein kinase C (PKC) | NA+/H+ EXCHANGER ACTIVITY | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANGIOTENSIN-II | VENTRICULAR MYOCYTES | extracellular-signal-regulated kinase (ERK) pathway | H+ EXCHANGER | PLASMA-MEMBRANE | cardiac myocyte | RAF-1 KINASE | PROTEIN-COUPLED RECEPTOR | acidosis | protein kinase C (PKC) | DEPENDENT ACTIVATION | Cells, Cultured - drug effects | Isotonic Solutions - pharmacology | Cation Transport Proteins - antagonists & inhibitors | Signal Transduction | Proto-Oncogene Proteins p21(ras) - genetics | Recombinant Fusion Proteins - physiology | Rats | Guanidines - pharmacology | Proto-Oncogene Proteins p21(ras) - physiology | Enzyme Activation - drug effects | Sulfones - pharmacology | Cells, Cultured - enzymology | Myocytes, Cardiac - enzymology | Ammonium Chloride - pharmacology | Organophosphonates - pharmacology | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Acidosis - enzymology | Sodium-Hydrogen Exchanger 1 | Sodium-Hydrogen Exchangers - antagonists & inhibitors | Hydrogen-Ion Concentration | Mitogen-Activated Protein Kinase 1 - metabolism | MEK, MAPK | pHi, intracellular pH | ERK kinase | FPT III, farnesyl protein transferase inhibitor III | NHE, Na+ | ERK, extracellular-signal-regulated kinase | HRP, horseradish peroxidase | GPCR, G-protein-coupled receptor | H+ exchanger | p90RSK, 90 kDa ribosomal S6 kinase | NRVM, neonatal rat ventricular myocytes | ARVM, adult rat ventricular myocytes | mM199, modified M199 | EGFP, enhanced green fluorescent protein | I.U., international units | PKC, protein kinase C | GEF, guanine nucleotide-exchange factor | Lsc, RGS domain of p115 RhoGEF | BIM I, bisindolylmaleimide I | MAPK, mitogen-activated protein kinase | RGS, regulator of G-protein signalling
Journal Article
Circulation Research, ISSN 0009-7330, 02/2008, Volume 102, Issue 2, pp. 157 - 163
The protein kinase D (PKD) family is a recent addition to the calcium/calmodulin-dependent protein kinase group of serine/threonine kinases, within the protein... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2011, Volume 286, Issue 7, pp. 5300 - 5310
In myocardium, the 90-kDa ribosomal S6 kinase (RSK) is activated by diverse stimuli and regulates the sarcolemmal Na+/H+ exchanger through direct... 
Antibodies
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 12/2007, Volume 43, Issue 6, p. 686
Protein kinase D (PKD) is activated downstream of protein kinase C (PKC) in many cell types, although little is known about the mechanisms that regulate PKD in... 
Protein kinases
Journal Article